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UrduNew research provides a better understanding of the mechanisms behind the development of amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, and points to a potential treatment strategy.
Tag: Alzheimer’s Disease
Does Estrogen Protect Against the Risk of Brain Shrinkage?
A new study found that people with higher cumulative estrogen exposure over their lifetime had greater brain volumes and fewer indicators of brain disease on their brain scans in midlife . The research is published in the November 3, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Cat’s Meow: Robotic Pet Boosts Mood, Behavior and Cognition in Adults with Dementia
Researchers tested the effectiveness of affordable, interactive robotic pet cats to improve mood, behavior and cognition in older adults with mild to moderate dementia.
Alzheimer’s Disease Among the Latinx Population: Preparing for a Growing Need in Care
Dr. Melissa Hladek and Jason Resendez join the Johns Hopkins School of Nursing’s On the Pulse podcast to discuss Alzheimer’s disease among the Latinx population.
Could a Novel Light Therapy Help People With Alzheimers?
Recently, the National Institutes of Health (NIH) awarded researchers at the Icahn School of Medicine at Mount Sinai a five-year grant to out whether exposing patients to a combination of light therapies will slow Alzheimer’s debilitating effects.
New research “sniffs out” how associative memories are formed
Has the scent of freshly baked chocolate chip cookies ever taken you back to afternoons at your grandmother’s house? Has an old song ever brought back memories of a first date? The ability to remember relationships between unrelated items (an odor and a location, a song and an event) is known as associative memory.
MIND Diet Linked to Better Cognitive Performance
Researchers at Rush University Medical Center have found that older adults may benefit from a specific diet called the MIND diet even when they develop these protein deposits, known as amyloid plaques and tangles.
Help ward off dementia, step by step
To mark Dementia Action Week and World Alzheimer’s Day, researchers at the University of South Australia are sharing their latest insights about dementia in a new podcast series, Re-imagining Ageing.
Rutgers expert available: World Alzheimer’s Day (9/22)
“Alzheimer’s disease is the only top 10 leading causes of death in the US without an effective treatment,” says William Hu, MD, PhD, FAAN. Dr. Hu is Associate Professor and Chief of Cognitive Neurology at Rutgers-RWJ Medical School and Rutgers Institute for Health, Health Care…
UF, UF Health announce gift and new $75 million initiative to expand Norman Fixel Institute
The University of Florida and UF Health on Tuesday, Sept. 14, announced an additional $25 million gift from the Lauren and Lee Fixel Family Foundation aimed at improving the lives of patients across the globe through the Norman Fixel Institute for Neurological Diseases at UF Health. The new investment will spur growth in the areas of national and international telemedicine, Alzheimer’s disease clinical research, mental health, traumatic brain injury and ALS and will help cultivate the next generation of expert researchers tackling these challenging diseases.
Time until dementia symptoms appear can be estimated via brain scan
Researchers at Washington University School of Medicine in St. Louis have developed an approach to estimating when a person with no cognitive symptoms will start showing signs of Alzheimer’s dementia based on data from brain scans and the person’s age.
Research reveals drug targets for memory enhancement
Bristol-led research has identified specific drug targets within the neural circuits that encode memories, paving the way for significant advances in the treatment of a broad spectrum of brain disorders.
UIC researchers find evidence of possible link between herpes simplex and neurogenerative diseases
A new study by researchers at University of Illinois Chicago suggests that when the protein optineurin, or OPTN, is present in cells it restricts the spread of HSV-1, the herpes simplex virus type 1.In a “first of its kind” study, researchers also found a potential direct connection between neurodegenerative diseases, such as Alzheimer’s disease, amyotrophic lateral sclerosis (ALS), glaucoma, and the herpesvirus.
As dementia’s toll on the U.S. rises, new study shows major gaps in who gets care that could help them remain at home
A new study provides stark statistics about a reality that 6 million Americans with dementia and their families live every day: one where people with dementia receive unpaid care from spouses and adult children, and where some rely on paid help. The study finds major disparities in potential family caregiver availability, and the chance that a person with dementia will move to a nursing home.
September is World Alzheimer’s Month & Healthy Aging Month
According to the Alzheimer’s Association, the number of Americans diagnosed with this disease is growing fast. An estimated 6.2 million Americans age 65 and older are living with Alzheimer’s dementia in 2021. By 2050, the number of people aged 65…
Mayo Clinic Conference on Brain Health and Dementia to welcome people living with dementia, caregivers and health care providers
The inaugural Mayo Clinic Conference on Brain Health and Dementia will be held virtually on Oct. 29 from 9:15 a.m. to 2:15 p.m. CDT with an optional workshop to follow. The event is a collaboration among Mayo Clinic, AARP and the Alzheimer’s Association.
Biomedical engineers show potential of new peptide for fighting Alzheimer’s disease and COVID-19
NYU Tandon professors Mary Cowman and Jin Ryoun Kim recently published a paper describing a novel peptide with broad therapeutic potential to combat chronic inflammation in multiple diseases.
Inflammatory Proteins Help Better Diagnose Progression of Alzheimer’s Disease
Testing for some inflammatory proteins associated with the nervous and immune systems will help diagnose the earlier onset and progression of Alzheimer’s disease, according to a Rutgers study.
New Study Provides Structural Insights into How Cholesterol in the Brain Regulates Ion Channels and Alters Their Function; Findings Could Facilitate the Development of Therapeutics for Neurological Diseases
UNDER EMBARGO UNTIL 11am EST on August 24: Cell Reports Senior Author: Paul A. Slesinger, PhD, Lillian and Henry M. Stratton Professor of Neuroscience and Director of the Center for Neurotechnology and Behavior, Icahn School of Medicine at Mount Sinai,…
Eyes Provide Peek at Alzheimer’s Disease Risk
Amyloid plaques found in the retinas of eyes may be an indicator of similar plaques in the brain, a hallmark of Alzheimer’s disease, and may provide a more visible biomarker for detecting disease risk.
Physical exercise modulates iron in Alzheimer’s disease
A recent experimental study shows how regular physical exercise modulates iron metabolism in both the brain and the muscles.
First of its kind study using multi-omics approach identifies large list of candidate genes associated with alcohol use disorder
New York, NY (Aug 20, 2021) – Researchers from the Icahn School of Medicine at Mount Sinai have published the first study of its kind in the field of addiction genetics using a multi-omics approach to provide a large list…
Flawed quality control in the brain
Proteins are the “tools” of our cells – they are essential to all vital tasks.
Stem cell treatment for dementia clears major hurdle
UCLA researchers have successfully grown restorative brain cells in large batches suitable for transplantation in patients. The therapy is designed to repair damage to the brain from white matter stroke, a “silent stroke” that can kick off years of cognitive deterioration and can accelerate Alzheimer’s disease. A new paper is published in the journal Stem Cell Research.
Stem cell treatment for dementia clears major hurdle
UCLA researchers have successfully grown restorative brain cells in large batches suitable for transplantation in patients. The therapy is designed to repair damage to the brain from white matter stroke, a “silent stroke” that can kick off years of cognitive deterioration and can accelerate Alzheimer’s disease. A new paper is published in the journal Stem Cell Research.
Do Some Diabetes Drugs Reduce the Risk of Alzheimer’s?
MINNEAPOLIS – People taking certain drugs to lower blood sugar for type 2 diabetes had less amyloid in the brain, a biomarker of Alzheimer’s disease, when compared to both people with type 2 diabetes not taking the drugs and people without diabetes. The new study, published in the August 11, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology, also found people taking these drugs, called dipeptidyl peptidase-4 inhibitors, showed slower cognitive decline than people in the other two groups.
Understanding Alzheimer’s Progression with Improvements to Imaging, Image Processing, Machine Learning
Because there is no ethical way to extract brain tissue from patients to look for clues about how amyloid plaques and protein aggregates proliferate, supplementary techniques are needed to better understand the progression of Alzheimer’s disease. During ACA’s 71st annual meeting, Abdullah Al Bashit, from Northeastern University, will discuss using computational techniques to help address these challenges. His work demonstrates how using small and wide-angle scattering along with state-of-the-art detection techniques will help probe the molecular structure and proliferation.
Fine particulate air pollution associated with higher risk of dementia
Using data from two large, long-running study projects in the Puget Sound region — one that began in the late 1970s measuring air pollution and another on risk factors for dementia that began in 1994 — University of Washington researchers identified a link between air pollution and dementia.
New grant to help advance Alzheimer’s disease research
A five-year, nearly $6 million grant from the National Institute on Aging will allow investigators with The University of Texas Health Science Center at Houston (UTHealth) School of Biomedical Informatics to use artificial intelligence (AI) to advance Alzheimer’s disease research.
Obesity and Cardiovascular Factors Combine to Cause Cognitive Decline in Latinos
Obesity is a major public health issue among Latinos, and a risk factor for Alzheimer’s disease. But in a new study, researchers at UC San Diego report that cardiometabolic abnormalities, such as hypertension, are more strongly associated with cognitive decline than obesity alone.
Global Dementia Cases Forecasted to Triple by 2050
Positive trends in global education access are expected to decrease dementia prevalence worldwide by 6.2 million cases by the year 2050.
65+ and Lonely? Don’t Talk to Your Doctor About Another Prescription
Lonely, older adults are nearly twice as likely to use opioids to ease pain and two-and-a-half times more likely to use sedatives and anti-anxiety medications, putting themselves at risk for drug dependency, impaired attention, falls and other accidents, and further cognitive impairment, according to a study by researchers at UC San Francisco.
Improving air quality reduces dementia risk, multiple studies suggest
DENVER, JULY 26, 2021 — Improving air quality may improve cognitive function and reduce dementia risk, according to several studies reported today at the Alzheimer’s Association International Conference® (AAIC®) 2021 in Denver and virtually. Previous reports have linked long-term air…
UNLV Alzheimer’s Researcher and Expert Panel Present First-Use Recommendations For Aducanumab
A group of six leading Alzheimer’s experts has convened to make the first recommendations for the appropriate use of aducanumab (Aduhelm, Biogen/Eisai), a newly approved treatment for early Alzheimer’s disease. The recommendations will help provide clinicians with greater clarity and…
Device cracks milk protein
‘Refolding’ molecules to support medical solutions
Neuroscientists posit that brain region is a key locus of learning
Small and seemingly specialized, the brain’s locus coeruleus (LC) region has been stereotyped for its outsized export of the arousal-stimulating neuromodulator norepinephrine. In a new paper and with a new grant from the National Institutes of Health, an MIT neuroscience…
Scientists Reverse Age-Related Memory Loss in Mice
Scientists at Cambridge and Leeds have successfully reversed age-related memory loss in mice and say their discovery could lead to the development of treatments to prevent memory loss in people as they age.
Scientists reverse age-related memory loss in mice
Scientists at Cambridge and Leeds have successfully reversed age-related memory loss in mice and say their discovery could lead to the development of treatments to prevent memory loss in people as they age. In a study published today in Molecular…
Evidence of sustained benefits of pimavanserin for dementia-related psychosis
Evidence of the sustained benefits of an investigational antipsychotic treatment for people with dementia-related psychosis has been published. Up to half of the 45 million people worldwide who are living with Alzheimer’s disease will experience psychotic episodes, a figure that…
Spinal Fluid Biomarkers Detect Neurodegeneration, Alzheimer’s Disease in Living Patients
New research reveals that the same framework of proteins and peptides that can detect Alzheimer’s disease in cerebrospinal fluid can also detect other forms of neurodegeneration, like frontotemporal degeneration.
Chemists Found an Effective Remedy For “Aged” Brain Diseases
Russian scientists have synthesized chemical compounds that can stop the degeneration of neurons in Alzheimer’s, Parkinson’s, and other severe brain pathologies.
Andrea Gilmore-Bykovskyi receives Rising Star Award in Health Services and Aging Research
Presented by the American Federation for Aging Research (AFAR)
Think About This: Keeping Your Brain Active May Delay Alzheimer’s Dementia 5 Years
Keeping your brain active in old age has always been a smart idea, but a new study suggests that reading, writing letters and playing card games or puzzles in later life may delay the onset of Alzheimer’s dementia by up to five years. The research is published in the July 14, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Metal-based molecules show promise against the build-up of Alzheimer’s peptides
In lab tests, Imperial researchers have created a metal-based molecule that inhibits the build-up of a peptide associated with Alzheimer’s disease. A peptide is a fragment of a protein, and one of the key hallmarks of Alzheimer’s disease is the…
Think about this: Keeping your brain active may delay Alzheimer’s dementia 5 years
MINNEAPOLIS – Keeping your brain active in old age has always been a smart idea, but a new study suggests that reading, writing letters and playing card games or puzzles in later life may delay the onset of Alzheimer’s dementia…
Researchers identify signaling molecule that may help prevent Alzheimer’s disease
Interleukin-3 may reprogram immune responses in the brain that cause cell death and lead to dementia.
Alzheimer’s Association Welcomes CMS Announcement of National Coverage Determination Analysis on Treatment for Alzheimer’s Disease
On behalf of all those living with Alzheimer’s disease, their caregivers, and their families, we appreciate the Centers for Medicare & Medicaid Services (CMS) thoughtful consideration on coverage considerations for monoclonal antibodies targeting amyloid for the treatment of Alzheimer’s disease, including aducanumab, which was recently approved by the Food and Drug Administration (FDA).
Recent study identifies 11 candidate genetic variants for Alzheimer’s disease
LEXINGTON, Ky. (July 13, 2021) — A recently published study co-authored by University of Kentucky Sanders-Brown Center on Aging researcher Justin Miller, Ph.D., identifies 11 rare candidate variants for Alzheimer’s disease. Researchers found 19 different families in Utah that suffered…
A Trojan horse could help get drugs past our brain’s tough border patrol
Sclerosis, Parkinson’s Disease, Alzheimer’s and epilepsy are but a few of the central nervous system disorders. They are also very difficult to treat, since the brain is protected by the blood-brain barrier. The blood-brain barrier works as a border wall…
Preferred life expectancy and its association with hypothetical adverse life scenarios
July 12, 2021– A new study sheds light on how the specter of dementia and chronic pain reduce people’s desire to live into older ages. Among Norwegians 60 years of age and older the desire to live into advanced ages…