For the first time, researchers at the University of Minnesota Twin Cities showed that non-invasive brain stimulation can change a specific brain mechanism that is directly related to human behavior.
Tag: Alzheimer’s Disease
“Anti-Choke Mug” – Chula Innovation for Neuro Patients to Drink Water Confidently
Chula Medicine has designed an anti-choke mug with calculated angle, amount, and time of water flow from the mug to the patient’s lips hoping to reduce choking that may lead to lung infection, bring peace of mind to caregivers, and make it safer for patients who will have a better quality of life.
‘Curved’ Walking and a Depth Camera: New Tool Detects Early Cognitive Decline
Gait impairments often are prevalent in the early stages of cognitive decline. Researchers quantitatively compared straight walking and curved walking – a more natural yet complex activity – in healthy older adults and adults with mild cognitive impairment (MCI). A depth camera detected and tracked 25 joints of body movement and signals were processed to extract 50 gait markers. Intriguingly, curved walking illuminated notable disparities between the study groups.
Wrist Device That Monitors Activity Could Help Provide Early Warning of Alzheimer’s
Monitoring daily activity patterns using a wrist-worn device may detect early warning signs of Alzheimer’s disease, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health.
Doctor discusses a recent study about dementia.
Tresa Mcneal, MD, at Baylor Scott & White Health, discusses a recent study about dementia. What You Need to Know: Dementia affects thinking, memory and social ability. Stroke can cause dementia. Dementia risks increase for those who are sedentary. Reduce…
Study Detects Cognitive Changes in Older Drivers Using In-vehicle Sensors
Continuous, unobtrusive sensors and related monitoring devices are installed in older drivers’ vehicles to detect changes in highly complex activities over time. A driver facing camera, forward facing camera, and telematics unit provide video in real-time to enable researchers to analyze abnormal driving such as getting lost, reaction time and braking patterns as well as travel patterns such as miles driven, miles during the night and daytime, and driving in severe weather. Detecting changes in behavior could generate early warning signs of possible changes in cognition.
Neurons help flush waste out of brain during sleep
Researchers at Washington University School of Medicine in St. Louis have found that brain cell activity during sleep is responsible for propelling fluid into, through and out of the brain, cleaning it of debris.
AI Finds Key Signs That Predict Patient Survival Across Dementia Types
Researchers at the Icahn School of Medicine at Mount Sinai and others have harnessed the power of machine learning to identify key predictors of mortality in dementia patients. The study, published in the February 28 online issue of Communications Medicine, addresses critical challenges in dementia care by pinpointing patients at high risk of near-term death and uncovers the factors that drive this risk. Unlike previous studies that focused on diagnosing dementia, this research delves into predicting patient prognosis, shedding light on mortality risks and contributing factors in various kinds of dementia.
Yoga provides unique cognitive benefits to older women at risk of Alzheimer’s disease, study finds
A new UCLA Health study found Kundalini yoga provided several benefits to cognition and memory for older women at risk of developing Alzheimer’s disease including restoring neural pathways, preventing brain matter decline and reversing aging and inflammation-associated biomarkers – improvements not seen in a group who received standard memory training exercises.
Fixing rogue brain cells may hold key to preventing neurodegeneration
A team led by scientists at the Case Western Reserve University School of Medicine has identified a new therapeutic approach for combating neurodegenerative diseases.
Drug Repairs Systems That Drain Alzheimer’s-Causing Waste From Brain, Study Shows
Rutgers study led by undergrads and gap-year students breaks ground in the field of neuroscience and suggests experimental medication could treat dementia.
Dementia Researchers Share Recruitment Strategies for Pragmatic Clinical Trial
The Dementia Care (D-CARE) Study (2019-2023), which was conducted at four clinical trial sites in the U.S., compared three approaches in dementia care. Despite challenges during the COVID-19 pandemic, D-CARE successfully enrolled 2,176 racially/ethnically diverse persons with Alzheimer’s disease or related dementias and their caregivers.
UC Irvine-led research team creates novel rabies viral vectors for neural circuit mapping
Irvine, Calif., Feb. 14, 2024 — A research team led by the University of California, Irvine has created 20 new recombinant rabies viral vectors for neural circuit mapping that offer a range of significant advantages over existing tools, including the ability to detect microstructural changes in models of aging and Alzheimer’s disease brain neurons.
Protein Accumulation on Fat Droplets Implicated in Late-Onset Alzheimer’s Disease
In an effort five years in the making, UNC School of Medicine cell biologist Sarah Cohen, PhD, and Rockefeller University’s Ian Windham, PhD, describe the interplay between fats and proteins in brain cells and how their dysfunction contributes to the development of late-onset Alzheimer’s disease.
Better together: Beckman imaging facilities share $3M Alzheimer’s research grant
Beckman researchers and collaborators received $3 million from the U.S. National Institute on Aging to develop diagnostic tools and imaging agents for the early detection of Alzheimer’s disease.
Dr. Claudia Padilla discusses Alzheimer’s and a new treatment.
Claudia Padilla, MD, at Baylor Scott & White Health, discusses Alzheimer’s and a new treatment. What You Need to Know: Alzheimer’s disease is a type of dementia. The most common sign is short-term memory loss. New medication targets the protein…
RNA Scientist Receives Federal Funding to Commercialize Molecular Tool Against Alzheimer’s Disease
University at Albany scientist Scott Tenenbaum, founder of UAlbany spinoff company sxRNA Technologies, Inc. (sxRNA Tech), has received $500,000 from the National Institute on Aging, part of the National Institutes of Health, to study how aging brain cells shape the progression of Alzheimer’s disease, and advance RNA technology that could inform new therapeutics to prevent and treat Alzheimer’s and related dementias.
RUDN chemists suppress overactivity of enzymes that cause Alzheimer’s disease
RUDN University chemists have obtained new azaheterocyclic compounds that inhibit acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), regulators of the central nervous system.
Residents of Rural ‘Glades’ Take a ‘Leap of Faith’ to Combat Dementia
Compared to urban dwellers, racially/ethnically diverse older adults face up to an 80 percent greater risk of cognitive impairment in older age, and 2.5 times potentially preventable Alzheimer’s-related (ADRD) hospitalizations.
Re-energizing mitochondria to treat Alzheimer’s disease
Nerve cells in the brain demand an enormous amount of energy to survive and maintain their connections for communicating with other nerve cells.
Vaccines May Protect Against Alzheimer’s, But How? Asks Domenico Praticò, MD, FCPP
Commonly used vaccines may also protect against dementia, according to a recent paper published in the Journal of Alzheimer’s Disease [J. Alzheimer’s Disease 2023; 95(2): 703–718)]. The authors found that after receiving the tetanus/diphtheria vaccine and whooping cough (aka, pertussis)…
Hackensack Meridian Health Conducting Research on Alzheimer’s Disease Through Multiple Clinical Trials as Well as Providing Patients with Preventive Care
November is National Alzheimer’s Disease Month Hackensack Meridian Hackensack University Medical Center and the hospital’s Center for Memory Loss and Brain Health are conducting research for Alzheimer’s Disease through four clinical trials with the goal of addressing and improving the…
IU scientists part of NIH-funded national consortium focused on improving Alzheimer’s disease diagnoses
Researchers at Indiana University School of Medicine will play key roles in a national consortium led by Wake Forest University School of Medicine to study the use, interpretation and implementation of biomarkers to diagnose Alzheimer’s disease. The multi-institution effort is funded by a five-year, $9 million grant from the National Institute on Aging, part of the National Institutes of Health, that will establish the Alzheimer’s Diagnosis in Older Adults with Chronic Conditions (ADACC) Network.
New $81M NIH grant will help U.S. answer urgent need for better dementia care
Fueled by new five-year funding expected to total $81 million from the NIH’s National Institute on Aging, a multi-institution team will work to improve understanding of the health care workforce that cares for people with dementia, through surveys and other methods that will produce data for clinicians, researchers, policymakers and others to use.
Rutgers Receives $4.2 Million to Develop Center for Alzheimer’s and Dementia Research in Asian and Pacific Americans
The Resource Center for Alzheimer’s and Dementia Research in Asian and Pacific Americans will work to advance behavioral, social and economic research related to Alzheimer’s disease and other dementias especially in older Asian and Pacific Americans.
Researchers Connect Alzheimer’s-Associated Genetic Variants with Brain Cell Function
Led by scientists at UNC-Chapel Hill and UC-San Francisco, research reveals new non-coding genetic variants associated with Alzheimer’s disease functioning in microglia – brain cells already implicated in the progression of this often-fatal neurodegenerative condition.
World Alzheimer’s Month 2023: Shining a Light on Alzheimer’s – Domenico Praticò
Since 2012, September has been celebrated as World Alzheimer’s Month. Back then, and only eleven years ago, an average of 2 out of 3 people had little understanding of Alzheimer’s disease and associated dementias.
FAU Receives $1.3 Million Grant for Alzheimer’s Outreach in Broward County
The three-year, $1.3 million grant from the Administration for Community Living’s Alzheimer’s Disease Program Initiative will support a groundbreaking project designed to advance health equity and improve quality of life for individuals living with or at high risk for Alzheimer’s disease and related dementias and their family caregivers.
Cholesterol and Inflammation Demonstrate Alzheimer’s Link
A recent study shows that a protein called ABCA7 plays a functional role as a potential biological link between cholesterol and inflammation in Alzheimer’s disease. The new work was published online August 25 in the journal Cells.
FAU Receives $750,000 Philanthropic Grant for Alzheimer’s Disease
A $750,000 philanthropic grant from the Carl Angus DeSantis Foundation will help FAU develop partnerships and programs that will establish best practice for coordinated care and research for Alzheimer’s disease and related dementias.
Specialized T cells in the brain slow progression of Alzheimer’s disease
Scientists at St. Jude Children’s Research Hospital found that a subset of CD8+ T cells in the brain lessens the activation of microglia and limits disease pathology in a model of Alzheimer’s disease.
Blood biomarker shows “great promise” predicting progression to Alzheimer’s disease in at-risk population
Neuroscience researchers at Wayne State University published a review article that confirms the usefulness of neurofilament light (NfL) blood levels to predict the likelihood and rate of progression of neurodegeneration in Alzheimer’s disease.
FAU Lands $4.2 Million NIH Grant for Air Quality and Alzheimer’s Risks Study
Lake Okeechobee rural residents are subjected to repeated, intermittent exposures to air pollution during agricultural fires.
Neuroscientists create new resource to improve Alzheimer’s disease research models
A new study by Indiana University School of Medicine researchers uses more genetically diverse mouse models to study the accumulation and spread of abnormal tau protein deposits in the brain.
Intermittent Fasting Improves Alzheimer’s Pathology
New results from researchers at UC San Diego School of Medicine suggest that intermittent fasting could be an effective treatment approach for Alzheimer’s disease.
Several vaccines associated with reduced risk of Alzheimer’s disease in adults 65 and older
Prior vaccination against tetanus and diphtheria, with or without pertussis (Tdap/Td); herpes zoster (HZ), better known as shingles; and pneumococcus are all associated with a reduced risk for developing Alzheimer’s disease, according to new research from UTHealth Houston.
Stem Cell Therapy Rescues Symptoms of Alzheimer’s Disease
Promising preclinical results from UC San Diego show hematopoietic stem cell therapy was effective in rescuing memory loss, neuroinflammation and beta amyloid build-up in a mouse model of Alzheimer’s disease.
AI model isolates olive oil ingredients that may fight Alzheimer’s
A growing body of evidence suggests extra virgin olive oil can help prevent cognitive decline due to Alzheimer’s disease. In a new study, Yale School of Medicine researchers led by Natalie Neumann, MD, trained a machine learning algorithm on current…
FSU researcher finds potential new tool for early identification of dementia risk
By analyzing data from nearly 13,000 subjects who participated in a long-term aging study, Florida State University researchers found that an interviewer’s rating of a cognitively healthy person’s memory successfully predicted the likelihood of developing dementia over a 15-year period.
Minds & eyes: Study shows dementia more common in older adults with vision issues
A new study lends further weight to the idea that vision problems and dementia are linked. In a sample of nearly 3,000 older adults who took vision tests and cognitive tests during home visits, the risk of dementia was much higher among those with eyesight problems – including those who weren’t able to see well even when they were wearing their usual eyeglasses or contact lenses.
Enhanced light sensitivity may contribute to Alzheimer’s ‘sundowning,’ disease progression
New Alzheimer’s research from UVA Health suggests that enhanced light sensitivity may contribute to “sundowning” – the worsening of symptoms late in the day – and spur sleep disruptions thought to contribute to the disease’s progression.
AAN Issues Guidance on New Treatments for Early Alzheimer’s Disease
New therapies for early Alzheimer’s disease, monoclonal antibodies that remove amyloid-β plaques in the brain, are bringing hope to people whose lives have been affected by the disease. To help neurologists discuss these therapies with patients and caregivers, the American Academy of Neurology has developed an Emerging Issues in Neurology article, published online on July 26, 2023, in Neurology®, the medical journal of the American Academy of Neurology.
Older women at risk for Alzheimer’s disease may benefit from yoga
Kundalini yoga, a form of yoga that focuses on breathing, meditation, and mental visualization, appeared beneficial for older women who had risk factors for Alzheimer’s disease and concerns about episodes of memory decline, according to a UCLA Health study.
AI Study Uncovers Olive Oil’s Potential in Combating Alzheimer’s Disease
A recent study has used Artificial Intelligence (AI) to reveal the remarkable potential of extra virgin olive oil (EVOO) in the fight against Alzheimer’s disease (AD). Researchers combined AI technology, chemistry, and omics research to identify specific bioactive compounds in EVOO that show promising effects in treating and preventing AD.
New study reveals why defense against brain corrosion declines in people with Alzheimer’s disease
A new study by researchers at Case Western Reserve University revealed that the progression of Alzheimer’s disease (AD) can be slowed by suppressing a specific protein in the brain that causes corrosion.
Opting for Olive Oil Could Boost Brain Health
A new study suggests that incorporating olive oil into your diet could help reduce the risk of dying from dementia.
Majority of older adults with cognitive impairment still drive
The majority of older adults with cognitive impairment are still driving, despite concerns raised by caregivers and others, a study finds. Researchers say it’s best for caregivers to start conversations surrounding driving earlier while the care recipient is able to understand and actively participate in the discussion.
$200,000 award for proof dogs can sniff Alzheimer’s disease, says Dr. Leslie Norins of Alzheimer’s Germ Quest
Parkinson’s disease, another neurodegenerative process, produces in patients a unique smell, which trained dogs can detect. Alzheimer’s disease, the leading dementia, needs to be similarly studied. This $200,000 challenge award is posted to help stimulate this necessary research.
Dr. Liana Apostolova is available to comment on new results of a phase III clinical trial of Donanemab, an Alzheimer’s disease medication for patients with early symptoms of the disease.
Liana Apostolova, MD is the associate dean of Alzheimer’s disease research at Indiana University School of Medicine. Dr. Apostolova and others presented results of the phase 3 clinical trial of Donanemab at the Alzheimer’s Association International Conference. The study, also published…
NUTRITION 2023 Press Materials Available Now
Press materials are now available for NUTRITION 2023, the annual flagship meeting of the American Society for Nutrition (ASN).