news, journals and articles from all over the world.
Researchers at Harvard Medical School and at Brigham and Women’s Hospital are adapting an antibody-detection tool to study the aftermath of infections by the novel coronavirus that is causing the current global pandemic.
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The continuing epidemic of pre-term birth includes this stark reality: tiny, fragile babies are born with underdeveloped lungs and prone to lifelong respiratory infections and related chronic illnesses. Cincinnati Children’s researchers report in Immunology the discovery of a complex biological process could in the development of cost effective treatments to help babies develop lifelong pulmonary resistance to respiratory infections.
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Researchers have discovered that the brains of developing embryos provide signals to a nascent immune system that help it ward off infections and significantly improve the embryo’s ability to survive a bacterial challenge. Viable brainless frog embryos can survive for some time, but exhibit chaotic and ineffective responses.
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The results of the B Part of It study – the largest meningococcal B herd immunity study ever conducted – are published today in the New England Journal of Medicine.
Read more-Newborn mice derive protective antibodies from their mothers’ microbiota
-Antibodies derived from mothers’ microbiota ward off both localized and widespread systemic infections by the bacterium E. coli
-Study points to the role of maternal microbes in offspring protection and neonatal immunity
-Findings can inform development of microbe-based therapies against infectious diarrhea in infants
Study in mice shows the nervous system not only detects the presence of Salmonella in the gut but actively stops the organism from infecting the body
Nerves in the gut prevent Salmonella infection by shutting the cellular gates that allow bacteria to invade the intestine and spread beyond it
As a second line of defense, gut neurons help avert Salmonella invasion by maintaining the levels of key protective microbes in the gut
Findings reveal prominent role for nervous system in infection protection and regulation of immunity
News release about a new collaborative study led by Cleveland Clinic and University Hospitals finding that commonly used clinical indicators of immune status and inflammation can predict mortality in the general population.
Read moreStudy shows measles wipes out 20 to 50 percent of antibodies against an array of viruses and bacteria, depleting a child’s previous immunity
Measles-ravaged immune system must “relearn” how to protect the body against infections
Study details mechanism and scope of this measles-induced “immune amnesia”
Findings underscore importance of measles vaccination, suggesting those infected with measles may benefit from booster shots of all previous childhood vaccines
The study, conducted in mice, is the first to show that creatine uptake is critical to the anti-tumor activities of killer T cells, the foot soldiers of the immune system.
Read moreHarvard Medical School has selected the 2019 media fellows for the second of its two thematic tracks this year: Immunity and Inflammation: A friend, a foe (Nov. 4-8).
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The first comprehensive look at the immune system of the fetal gut shows that it is far more developed before birth, and could help develop new maternal vaccines and understand if we are predisposed to autoimmune diseases before birth.
Read moreBlocking the mineralocorticoid receptor (MR)—a protein that helps maintain normal levels of salt and water in the body—in immune cells may help reduce the risk of heart attack and stroke by improving blood vessel health. The study will be presented today at the American Physiological Society (APS) Aldosterone and ENaC in Health and Disease: The Kidney and Beyond Conference in Estes Park, Colo.
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