Research Group Identifies Potential Therapeutic Target for Lupus
Inhibiting IRE1α, a molecule activated by the endoplasmic reticulum in neutrophils, counters disease progression in lupus mice.
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Cancer Immunotherapy May Also Treat Certain Autoimmune Diseases
The new approach blocks the interaction between cancer cells and immune receptors, showing promise in mice.
Read moreStudy Reveals Details of Immune Defense Guidance System
At the beginning of an immune response, a molecule known to mobilize immune cells into the bloodstream, where they home in on infection sites, rapidly shifts position, a new study shows. Researchers say this indirectly amplifies the attack on foreign microbes or the body’s own tissues.
Read moreExpert Alert: Encephalitis prevention another reason to receive COVID-19 vaccine
Patients with COVID-19 are at risk for neurologic complications, including encephalitis, or inflammation of the brain.
“Encephalitis cases have been reported in patients with COVID-19, although on the whole it appears to be a relatively rare complication,” says Michel Toledano, M.D., a Mayo Clinic neurologist.
In the case of encephalitis caused by communicable diseases for which there is a vaccine available, getting vaccinated is the best way of preventing the disease.
Read moreSTUDY PINS DOWN NUMBER OF AMERICANS WITH MOST COMMON FORM OF LUPUS
Just over 200,000 Americans suffer from systemic lupus erythematosus, or SLE, a condition in which the body’s immune system mistakenly attacks its own healthy tissues, especially joints and skin, a new study shows.
Read moreNational Research Effort Discovers Relationship Between Inflammation, Metabolism and Scleroderma Scarring
Study finds NAD+ break down leads to multi organ scarring, providing now a previously undiscovered pathogenic role of the enzyme CD38 in disease scarring.
Read moreAARDA Announces Leadership Transition
The American Autoimmune Related Diseases Association announced that Randall Rutta, President and CEO, is leaving to join the National Health Council (NHC) as its CEO, effective February 12, 2021.
Read moreProtein Linked to Progressive Lung Scarring in Scleroderma Patients
Osteopontin is discovered as the culprit behind these patients’ main cause of death. However, a repurposed immunosuppressive drug may combat the pro-inflammatory protein.
Read moreStudy explores sleep apnea, autoimmune disease link
New research by University of Georgia scientists sheds light on why people with obstructive sleep apnea may have associated autoimmune disorders. The results could lead to better approaches to treatment and possibly new drug therapies.
Read morePhysicians issue warning about rare neurological condition, expected to appear this fall
Pediatricians Henry David, MD, and Madan Kumar, DO, of the University of Chicago Medicine Comer Children’s Hospital warn parents of young children to watch out for symptoms of acute flaccid myelitis (AFM), a rare neurological disorder linked to viral infections that can lead to permanent paralysis.
Read moreAmerican College of Rheumatology Secures $7M Grant to Address Gaps in Lupus Care and Treatment
The American College of Rheumatology (ACR) was recently awarded a $7M grant to reduce inequities in symptom recognition, care and disease management of systemic lupus erythematosus (lupus). The grant, which will be led by the ACR’s Collaborative Initiatives (COIN) department, begins on Sept. 30.
Read moreChildren Who Take Prescription Steroids at Increased Risk for Diabetes, High Blood Pressure, Blood Clots
Children who take oral steroids to treat asthma or autoimmune diseases have an increased risk of diabetes, high blood pressure, and blood clots, according to Rutgers researchers.
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Pregnant mother’s immunity tied to behavioral, emotional challenges for kids with autism
Children with autism born to mothers who had immune conditions during their pregnancy are more likely to have behavioral and emotional problems, a UC Davis Health study has found. Offspring sex may also interact with maternal immune conditions to influence outcomes, particularly in terms of a child’s cognition.
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AARDA MOURNS THE LOSS OF DR. NOEL R. ROSE, “THE FATHER OF AUTOIMMUNITY”
AARDA Tribute to Dr. Noel R. Rose, “The Father of Autoimmunity”
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Study: Enzyme Could Prove Effective in Treating Tumors and Inflammatory Diseases in Lung
Findings from a research study, led by scientists at Henry Ford, suggest an enzyme could play an important role in the treatment of cancer and autoimmune diseases in the airway.
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Dual role discovered for molecule involved in autoimmune eye disease
The inflammatory molecule interleukin-17A (IL-17A) triggers immune cells that in turn reduce IL-17A’s pro-inflammatory activity, according to a study by National Eye Institute (NEI) researchers.
Read moreDNA Misfolding in White Blood Cells Increases Risk for Type 1 Diabetes
Researchers found, in mice, that changes in DNA sequence can trigger the chromosomes to misfold in a way that puts one at a heightened risk for Type 1 diabetes. The study revealed that differences in DNA sequences dramatically changed how the DNA was folded inside the nucleus, ultimately affecting the regulation of genes linked to the development Type 1 diabetes.
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AARDA Partners with AutoimmuneMom
Detroit, MI (January 30, 2019) – The American Autoimmune Related Disease Association (AARDA) is thrilled to announce our new partnership with AutoimmuneMom. For the last seven+ years, AutoimmuneMom has created a digital community through the hard work and dedication of Katie Cleary. Now, AARDA will proudly host the content that has brought together people with autoimmune disease through stories of how autoimmune disease impacts motherhood and pregnancy, general autoimmune information, personal stories, and doctor recommendations. AutoimmuneMom will continue to maintain its social media presence, but all website content will be hosted on AARDA.org.
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Cedars-Sinai Receives $20M to Create Kao Autoimmunity Institute
Cedars-Sinai today announced a $20 million gift from Dr. and Mrs. Min H. Kao and the Kao Family Foundation to create the Kao Autoimmunity Institute to advance research and treatment of rheumatologic diseases. The gift also will establish the Scleroderma Program within the institute to provide interdisciplinary and integrated care for scleroderma patients and to support research, outreach, training and education to help those with the disease.
Read morePenn Researchers Uncover Dose of Medication More Likely to Put Patients with a Rare Autoimmune Disease into Complete Remission
Researchers from Penn compare a lymphoma-dose regimen of rituximab to a rheumatoid arthritis regimen for the treatment of pemphigus.
Read moreStudy: First Evidence of Immune Response Targeting Brain Cells in Autism
In a paper published in Annals of Neurology, a physician-scientist at Beth Israel Deaconess Medical Center (BIDMC), and colleagues report the presence of cellular features consistent with an immune response targeting specialized brain cells in more than two thirds of autistic brains analyzed postmortem. These cellular characteristics – not previously observed in autism – lend critical new insight into autism’s origins and could pave the way to improved diagnosis and treatment for people with this disorder.
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AUTOIMMUNE ASSOCIATION HOSTS TWO SIGNATURE EVENTS IN PITTSBURGH:
The American Autoimmune Related Diseases Association (AARDA) partners with AHN Autoimmunity Institute to present a free public forum on autoimmune disease and the inaugural Pittsburgh Autoimmune Walk.
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