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UrduDietary lipids play an essential role in regulating the function of the gut microbiota and gastrointestinal tract, and these luminal interactions contribute to mediating host metabolism. Palmitic Acid Hydroxy Stearic Acids (PAHSAs) are a family of lipids with
antidiabetic and anti-inflammatory properties, but whether the gut microbiota contributes to their beneficial effects on host metabolism is unknown.
Tag: gut microbiota
Gut microbiota modulating intestinal stem cell differentiation
Proliferation and differentiation of intestinal stem cell (ISC) to replace damaged gut mucosal epithelial cells in inflammatory states is a critical step in ameliorating gut inflammation. However, when this disordered proliferation continue
Alcohol misuse can disrupt gut microbiota, causing inflammation that leads to organ damage
Alcohol researchers have long known that excessive drinking can cause damage to the liver, pancreas, heart, muscle, bone, and brain. However, only a subset of patients with alcohol use disorder (AUD) appear to develop organ damage. New research shows that alcohol-induced gut inflammation is the missing link between unhealthy drinking and organ damage among certain AUD patients.
Ingestible Microbiome Sampling Pill Technology Advances
Significant progress has been made in the development of a small device, about the size of a vitamin pill, that can be swallowed and passed through the gastrointestinal tract to sample and help identify the full inventory of microbiome bacteria in an individual.
Irregular sleep patterns associated with harmful gut bacteria
New research has found irregular sleep patterns are associated with harmful bacteria in your gut.
Deciphering the association between uterine microbiota and fertility in dairy cows
Reduced fertility prolongs the interval from calving to conception in dairy cows, resulting in significant economic losses to dairy farms.
Helping ‘good’ gut bacteria and clearing out the ‘bad’ — all in one treatment
Probiotics could be used as an effective treatment strategy for certain intestinal diseases, such as Crohn’s disease. Researchers reporting in ACS Central Science have developed a microgel delivery system for probiotics that keeps “good” bacteria safe while actively clearing out “bad” ones.
Brain-Belly Connection: Gut Health May Influence Likelihood of Developing Alzheimer’s
UNLV study pinpoints 10 bacterial groups associated with Alzheimer’s disease, provides new insights into the relationship between gut makeup and dementia.
A commensal-derived exopolysaccharide regulates ILC3-mediated diseases
Abstract Control ID Number: 472 The gut microbiota plays a fundamental role in controlling many facets of human physiology, with impacts on the immune system being chief among them. Although there have been increasing successes in identifying disease-regulating commensal bacteria,…
Diet has a bigger say on gut microbes than the intestinal defense molecules
Researchers at Umeå University, Sweden, have found that among the many factors that shape the intestinal microbiota composition, diet has a much stronger impact than defensins, which are intestinal defence molecules produced by the body.
A healthy microbiome may prevent deadly infections in critically ill people
Twenty to 50 per cent of all critically ill patients contract potentially deadly infections during their stay in the intensive care unit or in hospital after being in the ICU – markedly increasing the risk of death.
Babies’ gut microbiome not influenced by mothers’ vaginal microbiome composition
It has been a longstanding assumption that birth mode and associated exposure of newborns to their mothers’ vaginal microbiome during delivery greatly affects the development of babies’ gut microbiome.
Human body a breeding ground for antimicrobial resistance genes
The community of microbes living in and on our bodies may be acting as a reservoir for antibiotic resistance, according to new research from the Earlham Institute and Quadram Institute in Norwich.
Gut microbes can help diagnose gestational diabetes as early as the first trimester of pregnancy
A new Bar-Ilan University study has found that gestational diabetes can be diagnosed as early as the first trimester of pregnancy — months earlier than typically detected.
Microbiome disturbances reported as signature of chronic fatigue syndrome/myalgic encephalomyelitis
New research reveals differences in the gut microbiomes of people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) compared to those of healthy controls.
A novel, powerful tool to unveil the communication between gut microbes and the brain
In the past decade, researchers have begun to appreciate the importance of a two-way communication that occurs between microbes in the gastrointestinal tract and the brain, known as the gut–brain axis.
Gut Microbes Differ in Men with Prostate Cancer
Researchers have found a significant difference in the gut microbiota of men with prostate cancer, compared with those who have benign biopsies.
Artificial Intelligence Analyzes Gut Microbiota of Fish to Detect Waters Compromised by Climate Change
Article title: Gut microbiota of wild fish as reporters of compromised aquatic environments sleuthed through machine learning Authors: John W. Turner Jr., Xi Cheng, Nilanjana Saferin, Ji-Youn Yeo, Tao Yang Bina Joe From the authors: “Overall, this study represents the…
Gut bacteria can make blood pressure medication less effective
A new study from The University of Toledo College of Medicine and Life Sciences has shown gut bacteria can reduce the effectiveness of certain blood pressure drugs.
The path from pollutants in food to a heightened allergic response
Exposure to the heavy metal cadmium is known to irritate the stomach and lungs or cause kidney disease, but new research links another health issue to inadvertently ingesting low doses of the pollutant: high activation of the antibodies that cause an allergic response.
Gut microbiota influences the ability to lose weight
Gut microbiota influences the ability to lose weight in humans, according to new research. The findings were published this week in mSystems, an open-access journal of the American Society for Microbiology.
No Clear Evidence Low-Calorie Sweeteners Harm Gut Microbiome but More Studies Warranted
New paper explores links among the diet, gut microbiota and health status.
Stress Responder Protein Found to Protect against Metabolic, Gut Changes in Mice
New research in mice suggests a protein found predominately in white blood cells helps keep gastrointestinal bacteria in balance and may protect against metabolic disorders.
Inflammatory Protein Found to Protect against Metabolic, Gut Changes in Mice
Article title: Lipocalin 2 deficiency-induced gut microbiota dysbiosis evokes metabolic syndrome in aged mice Authors: Vishal Singh, Sarah Galla, Rachel M. Golonka, Andrew D. Patterson, Benoit Chassaing, Bina Joe, Matam Vijay-Kumar From the authors: “Overall, the current study demonstrates that…
Antibiotics in Early Life Slows Digestive Nerve Function, Alters Microbiome
Article title: Antibiotic exposure postweaning disrupts the neurochemistry and function of enteric neurons mediating colonic motor activity Authors: Lin Y. Hung, Pavitha Parathan, Prapaporn Boonma, Qinglong Wu, Yi Wang, Anthony Haag, Ruth Ann Luna, Joel C. Bornstein, Tor C. Savidge, Jaime…
A MOTHER’S BUGS
-Newborn mice derive protective antibodies from their mothers’ microbiota
-Antibodies derived from mothers’ microbiota ward off both localized and widespread systemic infections by the bacterium E. coli
-Study points to the role of maternal microbes in offspring protection and neonatal immunity
-Findings can inform development of microbe-based therapies against infectious diarrhea in infants