Mass Eye and Ear Receives $4 Million Gift to Accelerate Research on Genetic Links to Alzheimer’s Disease Resistance

Mass Eye and Ear has received a five-year, $4 Million gift from Good Ventures to spur Dr. Joseph F. Arboleda-Velásquez’s groundbreaking work into Alzheimer’s disease genetic resistance. This transformational gift will enable Dr. Arboleda-Velásquez to build upon the recent discovery of a genetic mutation that protected a woman who had a high familial risk for the condition and amyloid plaque deposits in her brain against early-onset Alzheimer’s.

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Gene ID’d as potential therapeutic target for dementia in Parkinson’s

Researchers at Washington University School of Medicine in St. Louis have discovered that the genetic variant APOE4 – long linked to dementia – spurs the spread of harmful clumps of Parkinson’s proteins through the brain. The findings suggest that therapies that target APOE might reduce the risk of dementia for people with Parkinson’s disease.

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