news, journals and articles from all over the world.
A novel mechanism has been identified that might explain why a rare mutation is associated with familial Alzheimer’s disease in a new study by investigators at the University of Chicago.
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How do different parts of the body communicate? Scientists at St. Jude are studying how signals sent from skeletal muscle affect the brain.
Read moreResearchers have discovered that a widely used nutritional supplement may significantly reduce the risk of fatal strokes caused by a rare genetic disorder. Additionally, the findings suggest that the supplement could be used to both block precipitation of and break up the formation of amyloid plaque deposits, a common feature found in serious forms of dementia.
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One of the keys to having a healthy brain at any age is having a healthy blood-brain barrier, a complex interface of blood vessels that run through the brain. Research shows the blood-brain barrier leaks as we age, and we lose cells called pericytes. But could this leak and the difficulties in recall be the early stages of Alzheimer’s disease?
Read moreScientists at the Case Western Reserve University School of Medicine have determined the structure of protein “fibrils” linked to Lou Gehrig’s disease and other neurodegenerative disorders—findings that provide clues to how toxic proteins clump and spread between nerve cells in the brain.
Read morePeople over 65 shouldn’t take three or more medicines that act on their brain and nervous system, experts strongly warn, because the drugs can interact and raise the risk of everything from falls to overdoses to memory issues.
But a new study finds that 1 in 7 people with dementia who live outside nursing homes are taking at least three of these drugs.
An analysis of adult human brain tissue reveals over 900 proteins tied to epilepsy. The brain disorder, estimated to afflict more than 3 million Americans, is mostly known for symptoms of hallucinations, dreamlike states, and uncontrolled, often disabling bodily seizures.
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March Science Snapshots from Berkeley Lab
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Researchers at UC San Diego School of Medicine and elsewhere have identified a new drug that could prevent AD by modulating, rather than inhibiting, a key enzyme involved in forming amyloid plaques.
Read moreArticle title: Increased cholinergic activity under conditions of low estrogen leads to adverse cardiac remodeling Authors: Vanessa P. Teixeira, Kiany
Read morePeople with enlarged fluid-filled spaces in the brain around small blood vessels may be more likely to develop cognitive problems and dementia over time than people without these enlarged spaces, according to a new study published in the January 27, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Read moreA report released today estimates that about 10,000 Washington, D.C. residents 65 and older are living with dementia, a general term for a range of memory loss disorders, including Alzheimer’s disease.
Read moreStudy by researchers at Rush University Medical Center finds adding more foods that are part of Western diet may reduce cognitive benefits of Mediterranean diet.
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On January 6, 2021, Hackensack Meridian Hackensack University Medical Center’s Neuroscience Institute held a ribbon-cutting for its new Center for Memory Loss and Brain Health. The center will offer integrated, high-quality screening, diagnostic and treatment services for adults living with cognitive or memory impairment caused by conditions such as various types of dementia including Alzheimer’s disease.
Read moreWhile rates of dementia for the U.S. population have been relatively stable or in decline since 2000, rates for Black
Read moreDo I have COVID-19 or is it something else? Bobby Tajudeen, MD, director of rhinology, sinus surgery and skull base surgery at Rush University Medical Center explains the differences between common smell loss and smell loss as a COVID-19 symptom and when to see a specialist.
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A new project led by the University of South Australia will develop a virtual assistant tool to support around two million dementia carers in the Asia Pacific.
Read moreAs COVID-19 cases increase across the nation, many caregivers are trying to navigate the holidays for relatives with dementia or Alzheimer’s disease. The Centers for Disease Control and Prevention suggests that people not travel to limit the potential spread of the coronavirus.
Mary Catherine Lundquist, program director of Care2Caregivers, a peer counseling helpline (800-424-2494) for caregivers of people with dementia and Alzheimer’s disease operated by Rutgers Behavioral Health Care, discusses how families can stay connected with their loved ones.
A new analysis assesses how emerging artificial intelligence technologies can help older adults preserve their autonomy, and addresses ethical concerns that have been raised about the use of AI in so-called “carebots.”
Read moreA new study led by researchers at the Johns Hopkins Bloomberg School of Public Health and the Federal Reserve Board of Governors found that Medicare beneficiaries who go on to be diagnosed with dementia are more likely to miss payments on bills as early as six years before a clinical diagnosis.
Read moreBiogen tried, and failed, to win FDA committee approval for its anti-amyloid Alzheimer’s drug. The Alzheimer’s Association supported the application but did not reveal significant monies received from the firm.
Read moreWomen who work in the paid labor force in early adulthood and middle age may have slower memory decline later in life than women who do not work for pay, according to a new study published in the November 4, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology. Researchers found an association between working for pay and slower memory decline regardless of a woman’s marital or parenthood status.
Read moreDuring the COVID-19 pandemic, the sickest patients at the University of Alabama at Birmingham Hospital have had their troubles eased, however briefly, thanks to an innovative musical project. Helping those patients recover — and keeping their spirits up amid the isolation the virus requires — is the motivation for the project, an effort between UAB health care staff and the Alabama Symphony Orchestra.
Read moreDementia and other cognitive disorders now appear to be risk factors for developing severe COVID-19, according to research from the University of Georgia.
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A new tool for analyzing tissue damage seen on MRI brain scans can detect with more than 70 percent accuracy early signs of cognitive decline, new research shows.
MCI911.com had added a new department, Research Radar, to focus exclusively on advancements to aid fighting MCI
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A metabolite produced following consumption of dietary soy may decrease a key risk factor for dementia – with the help of the right bacteria, according to a new discovery.
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Older people who report greater levels of social engagement have more robust gray matter in regions of the brain relevant in dementia, according to new research. The findings matter during the COVID-19 pandemic.
Read moreOlder adults with severe apathy, or lack of interest in usual activities, may have a greater chance of developing dementia than people with few symptoms of apathy, according to a study published in the October 14, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Read moreBattling the mild cognitive impairment stage of Alzheimer’s may disease may “nip it in the bud”.
Read moreMisplacing keys, forgetting the way to a doctor’s appointment, trouble recalling a neighbor’s name: Are these examples of typical aging? What’s the difference between Alzheimer’s disease and other forms of dementia? What’s actually happening to the brain, and how can you keep it healthy?
Read moreA $53.6 million grant from the National Institutes of Health will aid brain scientists, including a researcher from The University of Texas Health Science Center at Houston (UTHealth), in studying the role of incidental white matter lesions, or WMLs, in dementia among diverse people with cognitive complaints.
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Researchers at Case Western Reserve University School of Medicine seek to optimize emerging methods of diagnosing two common neurodegenerative diseases—dementia with Lewy bodies and Parkinson’s disease dementia—which affect 1.4 million in the United States
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Joe Verghese, M.B.B.S., M.S., an international leader in aging and cognition research at Albert Einstein College of Medicine and Montefiore Health System, has received two grants from the National Institutes of Health totaling $13.8 million to conduct studies on pre-dementia and Alzheimer’s disease.
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Testing a readily and rapidly available, discreet in-vehicle sensing system could provide the first step toward future widespread, low-cost early warnings of cognitive change in older drivers. The use of an advanced, multimodal approach involves the development of novel driving sensors and integration of data from a battery of cognitive function tests, eye tracking and driving behaviors and factors. These in-vehicle technologies could help detect abnormal driving behavior that may be attributed to cognitive impairment.
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Middle-aged adults who report symptoms of insomnia and are sleeping less than six hours a night may be at increased risk of cognitive impairment, according to a study by Penn State College of Medicine researchers.
Read moreWorldwide, a person is diagnosed with dementia every three seconds. Regular physical activity and limited sedentary behavior (i.e., time spent
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Even mild concussions cause severe and long-lasting impairments in the brain’s ability to clean itself, and this may seed it for Alzheimer’s, dementia and other neurodegenerative problems.
Read moreThe paper explains that current therapeutic approaches to the treatment of Alzheimer’s disease focus on the major pathological hallmarks of the disease which are amyloid plaques and neurofibrillary tangles. They are the requirements for a diagnosis of Alzheimer’s disease. However, the authors say there has been an explosion of genetic data suggesting the risk for sporadic Alzheimer’s disease is driven by several other factors including neuroinflammation, membrane turnover and storage, and lipid metabolism.
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Working with their colleagues at the University of Pennsylvania, researchers at the University of Kentucky have found that they can differentiate between subtypes of dementia inducing brain disease. “For the first time we created criteria that could differentiate between frontotemporal dementia (FTD) and a common Alzheimer’s ‘mimic’ called LATE disease,” explained Dr. Peter Nelson of the Sanders-Brown Center on Aging at the University of Kentucky.
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School-based dementia education could deliver much needed empathy and understanding for older generations as new research from the University of South Australia shows it can significantly improve dementia knowledge and awareness among younger generations.
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Nearly three-quarters of older adults with dementia have filled prescriptions for medicines that act on their brain and nervous system, but aren’t designed for dementia, a new study shows. That’s despite the special risks that such drugs carry for older adults — and the lack of evidence that they actually ease dementia-related behavior problems.
Read moreNew research suggests that education provides little to no protection against the onset of cognitive declines later in life. It can, however, boost the cognitive skills people develop earlier in life, pushing back the point at which age-related dementia begins to impact a person’s ability to care for themselves.
Read moreSome people who feel dizzy or lightheaded when they stand up may have an increased risk of developing dementia years later, according to a new study published in the August 12, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology. The condition, called orthostatic hypotension, occurs when people experience a sudden drop in blood pressure when they stand up.
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The COVID-19 pandemic brought many things to a screeching halt and continues to impact our daily lives. However, important research at the University of Kentucky’s Sanders-Brown Center on Aging (SBCoA) is continuing under extreme caution and deep dedication.
A monumental study in the field of dementia research is set to get underway in the coming weeks at UK.
Read moreIn a reversal of trends, American baby boomers scored lower on a test of cognitive functioning than did members of previous generations, according to a new nationwide study.
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Twenty-eight world-leading dementia experts added three new risk factors in the new report — excessive alcohol intake and head injury in mid-life and air pollution in later life. These are in addition to nine factors previously identified by the commission in 2017.
Read moreGum disease, especially the kind that is irreversible and causes tooth loss, may be associated with mild cognitive impairment and dementia 20 years later, according to a study published in the July 29, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology.
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Researchers at Washington University School of Medicine in St. Louis have developed a technique to detect minute amounts of a protein fragment linked to Alzheimer’s disease in the blood. The study, which will be published July 28 in the Journal of Experimental Medicine (JEM), shows that levels of p-tau-217 are elevated during the early stages of Alzheimer’s disease and could lead to a simple blood test capable of diagnosing the neurodegenerative disorder years before any symptoms begin to appear.
Read moreDozens of molecules may tangle up with rogue bundles of tau, a protein that normally gives nerve fibers structure, to cause brain cell damage that contributes to neurodegenerative diseases, a new study shows.
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