Researchers are studying the brains of a subset of people with asymptomatic Alzheimer’s disease who, despite having amyloid plaque and tau buildup postmortem, experienced no diagnosable dementia symptoms while they were living.
Tag: Dementia
Community-Based Programs in Senior Centers May Lower Health Care Use and Costs for People with Dementia
Living with dementia in communities with senior centers providing access to adult day health and social services was associated with fewer hospitalizations and lower health care use and Medicare costs, according to researchers from Rutgers University-New Brunswick and the University of Massachusetts Boston.
Are Gender and Sexual Identity Linked to Brain Health?
LGBTQ+ people may be more likely to have negative brain health outcomes, including a higher risk of dementia and late-life depression, than people who are cisgender and straight, according to a study published in the September 25, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology. These results do not prove that sexual or gender diversity causes neurological diseases, they only show an association.
Some Diabetes Drugs Tied to Lower Risk of Dementia, Parkinson’s Disease
A class of drugs for diabetes may be associated with a lower risk of dementia and Parkinson’s disease, according to a study published in the September 18, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Researchers uncover shared cellular mechanisms across three major dementias
Researchers have for the first time identified degeneration-associated “molecular markers” – observable changes in cells and their gene-regulating networks – that are shared by several forms of dementia that affect different regions of the brain.
Addressing Alzheimer’s in American Indian communities
This $11 million IHS contract will create training for healthcare providers and support patients’ families in communities that have little access to such specialized care.
Registration open for 14th annual Markesbery Symposium on Aging and Dementia at the University of Kentucky
The 14th annual Markesbery Symposium on Aging and Dementia is set for Sept. 27-28. The symposium, hosted by UK’s Sanders-Brown Center on Aging, is named in honor and memory of the late William R. Markesbery, M.D., the founding director of Sanders-Brown.
In Parkinson’s, Dementia May Occur Less Often, or Later, than Thought
There’s some good news for people with Parkinson’s disease: The risk of developing dementia may be lower than previously thought, or dementia may occur later in the course of the disease than previously reported, according to a study published in the August 7, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Expert Available: Does Your Morning Java Protect Against Dementia?
A new study suggests drinking two or more cups of coffee per day was associated with a nearly 30% decreased risk of dementia over a 7-year period. Moderate tea drinking was also associated with a… …
Researchers Discover Cholesterol Drug’s Potential as Treatment for Alzheimer’s, Other Dementia
Researchers from the University of Arkansas for Medical Sciences (UAMS) have discovered that an FDA-approved cholesterol drug holds the potential to disrupt the progression of Alzheimer’s disease and other forms of dementia.
Sanders-Brown Center on Aging launches innovative Brain Health Activities program
The University of Kentucky’s Sanders-Brown Center on Aging has introduced a groundbreaking initiative, Brain Health Activities, aimed at supporting individuals with dementia and their caregivers.
New dementia prevention & care report: Two Univ. of Michigan experts available to comment
Two University of Michigan experts whose work is cited in a landmark new Lancet Commission report on dementia prevention and care are available to comment. They’re especially able to comment on the 14 risk factors that the commission says people…
AI boosts the power of EEGs, enabling neurologists to quickly, precisely pinpoint signs of dementia
Mayo Clinic scientists are using artificial intelligence (AI) and machine learning to analyze electroencephalogram (EEG) tests more quickly and precisely, enabling neurologists to find early signs of dementia among data that typically go unexamined.
Does Your Body Composition Affect Your Risk of Dementia or Parkinson’s?
People with high levels of body fat stored in their belly or arms may be more likely to develop diseases like Alzheimer’s and Parkinson’s than people with low levels of fat in these areas, according to a study published in the July 24, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
UCLA selected by Centers for Medicare & Medicaid Services to test Medicare dementia care model
UCLA has been selected by the Centers for Medicare & Medicaid Services (CMS) to participate in a new Medicare alternative payment model designed to support people living with dementia and their caregivers.
Racial disparities in dementia determined by social factors
A study conducted in four Latin American countries by researchers at Washington University School of Medicine in St. Louis reveals that racial disparities in brain health are due to social factors, with genetic ancestry playing no role.
Mount Sinai Health System Selected by Centers for Medicare & Medicaid Services to Test Medicare Dementia Care Model
The Mount Sinai Health System announced it had been selected by the Centers for Medicare & Medicaid Services (CMS) to participate in a new Medicare alternative payment model designed to support people living with dementia and their caregivers.
Advocate Health champions health equity through new, innovative dementia care model
Advocate Health has been selected by the Centers for Medicare and Medicaid Services (CMS) to participate in the Guiding an Improved Dementia Experience (GUIDE) Model. Following years of neurocognitive disorders research pioneered by Advocate Health’s academic core, Wake Forest University School of Medicine, patients across the health system’s footprint will now benefit from the GUIDE Model’s new standardized approach to care for patients with dementia and their caregivers.
Can Inflammation in Early Adulthood Affect Memory, Thinking in Middle Age?
Having higher levels of inflammation in your 20s and 30s may be linked to having memory and thinking problems at middle age, according to a study published in the July 3, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study looked at levels of C-reactive protein (CRP) in the blood.
Expert available: FDA approval of Alzheimer’s disease drug, donanemab
The FDA approved a new Alzheimer’s disease treatment today called donanemab (brand name Kisunla), after it was reviewed and recommended by an advisory panel earlier this year. Sanjeev Vaishnavi, MD, PhD, an assistant professor of neurology at Penn Medicine, is…
New research identifies biomarkers that link alcohol use disorder and Alzheimer disease
Researchers agree that alcohol use can produce global and regional tissue volume changes in the brain, and that excessive alcohol use is associated with dementia and cognitive decline. A new study has examined the relationship between Alzheimer disease – the most common type of dementia – and alcohol use disorder (AUD), discovering biomarkers that link the two.
‘Fit2Drive’ Transforms Assessing Older Drivers with Cognitive Decline
With the help of an evidence-based calculator called “Fit2Drive,” researchers have made it easy to administer and evaluate an in-office test to predict an older individual’s probability of passing an on-road driving test. Based upon brief, easily administered cognitive tests, Fit2Drive provides an objective estimation of the ability to drive for those with cognitive concerns. Results show that the Fit2Drive algorithm demonstrated a strong 91.5% predictive accuracy.
Activating molecular target reverses multiple hallmarks of aging
Researchers at The University of Texas MD Anderson Cancer Center have demonstrated that therapeutically restoring ‘youthful’ levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms of aging in preclinical models. If these findings are confirmed in clinical studies, there may be therapeutic implications for age-related diseases such as Alzheimer’s, Parkinson’s, heart disease and cancer.
Alzheimer’s Awareness Month: Virginia Tech researchers work toward better treatments
Alzheimer’s disease, a deadly brain disease than can cause loss of memory and mobility, affects millions of lives daily. June marks Alzheimer’s and Brain Awareness Month, and Virginia Tech researchers are engaged in research meant to advance treatment for Alzheimer’s disease and assist caregivers of loved ones with dementia.
Removal of Ovaries Before Menopause Associated With Reduced White Matter in Brain
Women who have their ovaries removed before menopause, particularly before the age of 40, have reduced white matter integrity in multiple regions of the brain later in life.
Common Prostate Drugs Tied to Lower Risk of Dementia with Lewy Bodies
Certain drugs used to treat urinary symptoms due to an enlarged prostate may be associated with a reduced risk of dementia with Lewy bodies, according to a study published in the June 19, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
NUS linguists make breakthrough discovery on detecting early linguistic signs of dementia by studying the natural speech of seniors
A study led by linguists from the NUS Faculty of Arts and Social Sciences has found that early linguistic signs of dementia can be detected through the study of the natural speech of senior Singaporeans. The novel study revealed that participants with memory-related mild cognitive impairment spoke less and used fewer, but more abstract, nouns that is consistent with the speech pattern of Alzheimer’s patients.
Vigorous Exercise May Preserve Cognition in High-Risk Patients With Hypertension
People with high blood pressure have a higher risk of cognitive impairment, including dementia, but a new study from researchers at Wake Forest University School of Medicine suggests that engaging in vigorous physical activity more than once a week can lower that risk.
5-Minute Test Leads to Better Care for People with Dementia in the Primary Care Setting
The underdiagnosis of dementia, especially among Black and Hispanic patients, is a long-standing challenge in medicine.
Healthcare tip sheet: Topics for June & July – Ochsner Health experts available
As you plan for upcoming healthcare coverage in June and July, Ochsner Health has medical experts on standby to the discuss the timely and relevant topics listed below. June: Early signs of dementia you need to know– Dementia is not…
Mount Sinai Experts Present Research at SLEEP 2024
Sleep medicine experts available for interview on breaking and trending news about obstructive sleep apnea, CPAP, and more
Eating More Ultra-processed Foods Tied to Cognitive Decline, Stroke
People who eat more ultra-processed foods like soft drinks, chips and cookies may have a higher risk of having memory and thinking problems and having a stroke than those who eat fewer processed foods, according to a new study published in the May 22, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study does not prove that eating ultra-processed foods causes memory and thinking problems and stroke. It only shows an association.
Scientists aim to stop harmful gut bacteria triggering Alzheimer’s
Australian scientists are exploring how harmful gut bacteria from a poor diet can access the brain and trigger early onset Alzheimer’s disease.
Uniformed Services University Contributes to Groundbreaking Global Study on Multiple System Atrophy
In a groundbreaking study published May 2, 2024 in Neuron, researchers have identified four new genetic risk factors for multiple system atrophy (MSA), shedding light on this poorly understood disorder.
FAU Researchers Receive $1M in FDOH Grants to Fight Alzheimer’s Disease
With this funding, FAU researchers will shed light on the biological functions of Alzheimer’s disease (AD) by taking advantage of synthetic chemistry strategies; provide an innovative online screening tool for older drivers with cognitive decline; and gain a deeper understanding of the role of brain cholesterol in AD.
Innovative Microscopy Demystifies Metabolism of Alzheimer’s
Using state-of-the-art microscopy techniques developed on campus, researchers at UC San Diego School of Medicine have shed new light on the underlying mechanisms driving Alzheimer’s disease.
Scientists identify cell vulnerability ‘fingerprint’ related to Parkinson’s, Lewy body dementia
A new study offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson’s disease and some dementias.
Study Reveals How Obesity Could Accelerate Aging in the Brain
A new study conducted in mice traces how obesity and a high-fat diet may accelerate aging in the blood vessels that supply blood to the brain. The work is being presented this week at the American Physiology Summit, the flagship annual meeting of the American Physiological Society.
Human brains are getting larger. That may be good news for dementia risk
A new study published in JAMA Neurology found human brains are getting bigger. The increased size may lead to a brain reserve, potentially reducing the risk of dementia.
New research at Case Western Reserve University aims to address racial disparities in cognitive decline
According to new research at Case Western Reserve University, connecting with friends is key to limiting social isolation—something researchers believe could also reduce Alzheimer’s, dementia
EXPERT INTERVIEW: Alzheimer’s Association report reveals new Alzheimer’s disease incidence, costs figures and dementia care barriers/challenges
EMBARGOED UNTIL 20 MARCH 2024 On March 20, the Alzheimer’s Association will release its 2024 Alzheimer’s Disease Facts and Figures report, which provides an in-depth look at the latest statistics and information on Alzheimer’s disease prevalence, incidence, mortality, caregiving, dementia care workforce,…
‘Curved’ Walking and a Depth Camera: New Tool Detects Early Cognitive Decline
Gait impairments often are prevalent in the early stages of cognitive decline. Researchers quantitatively compared straight walking and curved walking – a more natural yet complex activity – in healthy older adults and adults with mild cognitive impairment (MCI). A depth camera detected and tracked 25 joints of body movement and signals were processed to extract 50 gait markers. Intriguingly, curved walking illuminated notable disparities between the study groups.
Wrist Device That Monitors Activity Could Help Provide Early Warning of Alzheimer’s
Monitoring daily activity patterns using a wrist-worn device may detect early warning signs of Alzheimer’s disease, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health.
People with Essential Tremor May Have Increased Risk of Dementia
Dementia may be three times more common among people with essential tremor, a movement disorder that causes involuntary shaking, than the general population, according to research released today, March 6, 2024. The study will be presented at the American Academy of Neurology’s 76th Annual Meeting taking place April 13–18, 2024, in person in Denver and online.
Four University of Michigan research teams selected for virtual tournament of science
Four University of Michigan research teams have made the bracket of 64 teams for STAT Madness, a virtual tournament of science. They were picked for their groundbreaking work on brain cancer, heart transplant, dementia care and deadly fungal infections published in 2023.
Doctor discusses a recent study about dementia.
Tresa Mcneal, MD, at Baylor Scott & White Health, discusses a recent study about dementia. What You Need to Know: Dementia affects thinking, memory and social ability. Stroke can cause dementia. Dementia risks increase for those who are sedentary. Reduce…
Study Detects Cognitive Changes in Older Drivers Using In-vehicle Sensors
Continuous, unobtrusive sensors and related monitoring devices are installed in older drivers’ vehicles to detect changes in highly complex activities over time. A driver facing camera, forward facing camera, and telematics unit provide video in real-time to enable researchers to analyze abnormal driving such as getting lost, reaction time and braking patterns as well as travel patterns such as miles driven, miles during the night and daytime, and driving in severe weather. Detecting changes in behavior could generate early warning signs of possible changes in cognition.
Risk of hospital readmission after surgery is high for older Americans
A new Yale study finds an increased risk of hospital readmission for older Americans within 180 days of undergoing major surgery — a risk that is particularly acute for individuals who are frail or have dementia.
AI Finds Key Signs That Predict Patient Survival Across Dementia Types
Researchers at the Icahn School of Medicine at Mount Sinai and others have harnessed the power of machine learning to identify key predictors of mortality in dementia patients. The study, published in the February 28 online issue of Communications Medicine, addresses critical challenges in dementia care by pinpointing patients at high risk of near-term death and uncovers the factors that drive this risk. Unlike previous studies that focused on diagnosing dementia, this research delves into predicting patient prognosis, shedding light on mortality risks and contributing factors in various kinds of dementia.
Researchers make precious headway into a genetic form of Alzheimer’s disease
UC Santa Barbara researchers and collaborators in Colombia, Brazil and Germany are progressing toward an understanding of mechanisms that underlie Alzheimer’s disease, in particular an early-onset, genetic form that has afflicted generations of an extended family in Colombia.