It’s the global epidemic that affects two in every five adults, but as obesity continues to expand waistlines worldwide, researchers at the University of South Australia are warning that harmful body fat can also increase the risk of dementia and stroke.
A group of six leading Alzheimer’s experts has convened to make the first recommendations for the appropriate use of aducanumab (Aduhelm, Biogen/Eisai), a newly approved treatment for early Alzheimer’s disease. The recommendations will help provide clinicians with greater clarity and…
It’s a favourite first-order for the day, but while a quick coffee may perk us up, new research from the University of South Australia shows that too much could be dragging us down, especially when it comes to brain health.
Keeping your brain active in old age has always been a smart idea, but a new study suggests that reading, writing letters and playing card games or puzzles in later life may delay the onset of Alzheimer’s dementia by up to five years. The research is published in the July 14, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology.
The American Academy of Neurology (AAN), the world’s largest association of neurologists with more than 36,000 members, is issuing ethical guidance for neurologists and neuroscience professionals who care for people with Alzheimer’s disease and other dementias. The new position statement is published in the July 12, 2021 online issue of Neurology®, the medical journal of the American Academy of Neurology. This update to the 1996 AAN position statement was developed by the Ethics, Law, and Humanities Committee, a joint committee of the American Academy of Neurology, American Neurological Association and Child Neurology Society.
Hyperactive immune cells in the brain may play a role in the early development of the neurodegenerative disease Amyotrophic lateral sclerosis (ALS), and a form of dementia that strikes younger people, according to a study conducted by investigators from Cedars-Sinai and published in the journal Neuron.
Researchers have identified a new treatment candidate that appears to not only halt neurodegenerative symptoms in mouse models of dementia and Alzheimer’s disease, but also reverse the effects of the disorders.
Research suggests that changes in lifestyle may affect the risk for dementia. Dr. Chen Zhao discusses how changes such as increased physical activity could reduce the risk for dementia.
A team from Wayne State University recently published the results of a three-year study of cognitive changes in older adults who complained that their cognitive ability was worsening though clinical assessments showed no impairments. MRIs at 18-month intervals showed significant changes in functional connectivity in two areas of the brain.
Irvine, Calif., June 21, 2021 — A large-scale meta-analysis led by University of California, Irvine researchers provides the strongest evidence yet of which blood pressure medications help slow memory loss in older adults: those that can travel out of blood vessels and directly into the brain. The findings, published in the American Heart Association journal Hypertension, will be of interest to the 91 million Americans whose blood pressure is high enough to warrant medication, as well as the doctors who treat them.
Researchers at Washington University School of Medicine in St. Louis have found that high levels of a normal protein associated with reduced heart disease also protect against Alzheimer’s-like damage in mice, opening up new approaches to slowing or stopping brain damage and cognitive decline in people with Alzheimer’s.
It’s been named the world’s best diet for weight loss, but now researchers at the University of South Australia are confident that the Mediterranean Diet – combined with a daily bout of exercise – can also stave off dementia, slowing the decline in brain function that is commonly associated with older age.
As the global nonprofit leader in Alzheimer’s research and science we have extensively reviewed the clinical trial data for Aduhelm™ (aducanumab).
Until now, systemic biomarkers to measure exercise effects on brain function and that link to relevant metabolic responses were lacking. A study shows a memory biomarker, myokine Cathepsin B (CTSB), increased in older adults following a 26-week structured aerobic exercise training. The positive association between CTSB and cognition, and the substantial modulation of lipid metabolites implicated in dementia, support the beneficial effects of exercise training on brain function and brain health in asymptomatic individuals at risk for Alzheimer’s.
Designing a soundscape to improve quality of life for an individual is centered on putting their perception at the heart of the process. During the 180th ASA Meeting, Arezoo Talebzadeh from Ghent University will show how a personalized soundscape can help those with dementia by providing clues regarding time of day and place. The session, “Soundscape design for people with dementia; the correlation between psychoacoustic parameter and human perception,” will take place Wednesday, June 9.
Nikhil Palekar,* MD, Associate Professor of Psychiatry, Director of Geriatric Psychiatry, and Medical Director of the Center for Excellence for Alzheimer’s Disease at the Renaissance School of Medicine at Stony Brook University, is available to discuss the newly approved FDA…
The approval of a new Alzheimer’s disease drug is getting a lot of attention, but a recent scientific review of the evidence about dementia prevention shows an important role for primary care providers and patients to modify risk factors and protect brain health over the long term.
News outlets: In your coverage of the historic FDA approval of aducanumab, the first drug approved for disease modification of Alzheimer’s Disease, not just treatment of symptoms, please consider speaking with University of Maryland Medical Center neurologist Dr. Julia Biernot.…
Ruth M. Tappen, Ed.D., RN, FAAN, the Christine E. Lynn Eminent Scholar and professor in FAU’s Christine E. Lynn College of Nursing, is nationally and internationally renowned as an innovative researcher and scholar. Tappen was recently recognized as the “2021 Alliance World Class Faculty” honoree by the Greater Fort Lauderdale Alliance.
A world-first international study led by the University of South Australia has identified a new drug to stop athletes developing dementia after sustaining repeated head injuries in their career.
University of Kentucky Neuroscience Professor Greg Gerhardt’s new research program will provide answers to long-standing questions about the role of neurotransmitters GABA and glutamate in the progression of Alzheimer’s disease. A culmination of his nearly 40 years of brain research, Gerhardt’s study could help to develop new treatments for the disease.
Older people with type 1 diabetes who have been to the hospital at some point for both low and high blood sugar levels may be at six times greater risk for developing dementia years later. The research is published in the June 2, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study also found that people with type 1 diabetes who visit the hospital for just one of the blood sugar extremes may also be at greater risk for developing dementia.
A new measure of brain health developed by researchers at Rush University Medical Center may offer a novel approach to identifying individuals at risk of memory and thinking problems, according to research results published in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association on June 1.
Hackensack Meridian Health and Eisai Inc. Join Forces to Support the Expansion of Alzheimer’s Disease Detection and Services for Patients
The development of dementia, often from Alzheimer’s disease, late in life is associated with abnormal blood levels of dozens of proteins up to five years earlier.
Sounds like crickets chirping and the taste of warm buckwheat pancakes can spark the senses of people with dementia — a fact faculty and students at WVU used to develop a way for those people to experience parts of their cultural past and to relieve stress for their caregivers.
Research from Saint Louis University finds that adult patients who have received a Tdap vaccination have a 42% lower risk for dementia, compared with patients who are not vaccinated.
The symptoms of grief people feel for a loved one facing a life-limiting illness fluctuate over time, a new study found – suggesting that individuals can adjust to their emotional pain, but also revealing factors that can make pre-loss grief more severe.
Despite decades of research and investment, the genetic underpinnings of Alzheimer’s disease are still largely unknown, stymieing drug development and early diagnosis efforts. A new $10.7 million, five-year project aims to change that.
A one-time injection of an experimental stem cell therapy can repair brain damage and improve memory function in mice with conditions that replicate human strokes and dementia, a new UCLA study finds.
A novel mechanism has been identified that might explain why a rare mutation is associated with familial Alzheimer’s disease in a new study by investigators at the University of Chicago.
How do different parts of the body communicate? Scientists at St. Jude are studying how signals sent from skeletal muscle affect the brain.
Researchers have discovered that a widely used nutritional supplement may significantly reduce the risk of fatal strokes caused by a rare genetic disorder. Additionally, the findings suggest that the supplement could be used to both block precipitation of and break up the formation of amyloid plaque deposits, a common feature found in serious forms of dementia.
One of the keys to having a healthy brain at any age is having a healthy blood-brain barrier, a complex interface of blood vessels that run through the brain. Research shows the blood-brain barrier leaks as we age, and we lose cells called pericytes. But could this leak and the difficulties in recall be the early stages of Alzheimer’s disease?
Scientists at the Case Western Reserve University School of Medicine have determined the structure of protein “fibrils” linked to Lou Gehrig’s disease and other neurodegenerative disorders—findings that provide clues to how toxic proteins clump and spread between nerve cells in the brain.
People over 65 shouldn’t take three or more medicines that act on their brain and nervous system, experts strongly warn, because the drugs can interact and raise the risk of everything from falls to overdoses to memory issues.
But a new study finds that 1 in 7 people with dementia who live outside nursing homes are taking at least three of these drugs.
An analysis of adult human brain tissue reveals over 900 proteins tied to epilepsy. The brain disorder, estimated to afflict more than 3 million Americans, is mostly known for symptoms of hallucinations, dreamlike states, and uncontrolled, often disabling bodily seizures.
March Science Snapshots from Berkeley Lab
Researchers at UC San Diego School of Medicine and elsewhere have identified a new drug that could prevent AD by modulating, rather than inhibiting, a key enzyme involved in forming amyloid plaques.
Article title: Increased cholinergic activity under conditions of low estrogen leads to adverse cardiac remodeling Authors: Vanessa P. Teixeira, Kiany Miranda, Sergio Scalzo, Cibele Rocha-Resende, Mário Morais Silva, Geisa C. S. V. Tezini, Marcos B. Melo Melo MB, Fernando Pedro…
People with enlarged fluid-filled spaces in the brain around small blood vessels may be more likely to develop cognitive problems and dementia over time than people without these enlarged spaces, according to a new study published in the January 27, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology.
A report released today estimates that about 10,000 Washington, D.C. residents 65 and older are living with dementia, a general term for a range of memory loss disorders, including Alzheimer’s disease.
Study by researchers at Rush University Medical Center finds adding more foods that are part of Western diet may reduce cognitive benefits of Mediterranean diet.
On January 6, 2021, Hackensack Meridian Hackensack University Medical Center’s Neuroscience Institute held a ribbon-cutting for its new Center for Memory Loss and Brain Health. The center will offer integrated, high-quality screening, diagnostic and treatment services for adults living with cognitive or memory impairment caused by conditions such as various types of dementia including Alzheimer’s disease.
While rates of dementia for the U.S. population have been relatively stable or in decline since 2000, rates for Black Americans remain disproportionately high, according to a new study published in JAMA Neurology. Melinda C. Power, ScD, director of the…
Do I have COVID-19 or is it something else? Bobby Tajudeen, MD, director of rhinology, sinus surgery and skull base surgery at Rush University Medical Center explains the differences between common smell loss and smell loss as a COVID-19 symptom and when to see a specialist.
A new project led by the University of South Australia will develop a virtual assistant tool to support around two million dementia carers in the Asia Pacific.
As COVID-19 cases increase across the nation, many caregivers are trying to navigate the holidays for relatives with dementia or Alzheimer’s disease. The Centers for Disease Control and Prevention suggests that people not travel to limit the potential spread of the coronavirus.
Mary Catherine Lundquist, program director of Care2Caregivers, a peer counseling helpline (800-424-2494) for caregivers of people with dementia and Alzheimer’s disease operated by Rutgers Behavioral Health Care, discusses how families can stay connected with their loved ones.
A new analysis assesses how emerging artificial intelligence technologies can help older adults preserve their autonomy, and addresses ethical concerns that have been raised about the use of AI in so-called “carebots.”
A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health and the Federal Reserve Board of Governors found that Medicare beneficiaries who go on to be diagnosed with dementia are more likely to miss payments on bills as early as six years before a clinical diagnosis.