People with high levels of body fat stored in their belly or arms may be more likely to develop diseases like Alzheimer’s and Parkinson’s than people with low levels of fat in these areas, according to a study published in the July 24, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Tag: Dementia
UCLA selected by Centers for Medicare & Medicaid Services to test Medicare dementia care model
UCLA has been selected by the Centers for Medicare & Medicaid Services (CMS) to participate in a new Medicare alternative payment model designed to support people living with dementia and their caregivers.
Racial disparities in dementia determined by social factors
A study conducted in four Latin American countries by researchers at Washington University School of Medicine in St. Louis reveals that racial disparities in brain health are due to social factors, with genetic ancestry playing no role.
Mount Sinai Health System Selected by Centers for Medicare & Medicaid Services to Test Medicare Dementia Care Model
The Mount Sinai Health System announced it had been selected by the Centers for Medicare & Medicaid Services (CMS) to participate in a new Medicare alternative payment model designed to support people living with dementia and their caregivers.
Advocate Health champions health equity through new, innovative dementia care model
Advocate Health has been selected by the Centers for Medicare and Medicaid Services (CMS) to participate in the Guiding an Improved Dementia Experience (GUIDE) Model. Following years of neurocognitive disorders research pioneered by Advocate Health’s academic core, Wake Forest University School of Medicine, patients across the health system’s footprint will now benefit from the GUIDE Model’s new standardized approach to care for patients with dementia and their caregivers.
Can Inflammation in Early Adulthood Affect Memory, Thinking in Middle Age?
Having higher levels of inflammation in your 20s and 30s may be linked to having memory and thinking problems at middle age, according to a study published in the July 3, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study looked at levels of C-reactive protein (CRP) in the blood.
Expert available: FDA approval of Alzheimer’s disease drug, donanemab
The FDA approved a new Alzheimer’s disease treatment today called donanemab (brand name Kisunla), after it was reviewed and recommended by an advisory panel earlier this year. Sanjeev Vaishnavi, MD, PhD, an assistant professor of neurology at Penn Medicine, is…
New research identifies biomarkers that link alcohol use disorder and Alzheimer disease
Researchers agree that alcohol use can produce global and regional tissue volume changes in the brain, and that excessive alcohol use is associated with dementia and cognitive decline. A new study has examined the relationship between Alzheimer disease – the most common type of dementia – and alcohol use disorder (AUD), discovering biomarkers that link the two.
‘Fit2Drive’ Transforms Assessing Older Drivers with Cognitive Decline
With the help of an evidence-based calculator called “Fit2Drive,” researchers have made it easy to administer and evaluate an in-office test to predict an older individual’s probability of passing an on-road driving test. Based upon brief, easily administered cognitive tests, Fit2Drive provides an objective estimation of the ability to drive for those with cognitive concerns. Results show that the Fit2Drive algorithm demonstrated a strong 91.5% predictive accuracy.
Activating molecular target reverses multiple hallmarks of aging
Researchers at The University of Texas MD Anderson Cancer Center have demonstrated that therapeutically restoring ‘youthful’ levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms of aging in preclinical models. If these findings are confirmed in clinical studies, there may be therapeutic implications for age-related diseases such as Alzheimer’s, Parkinson’s, heart disease and cancer.
Alzheimer’s Awareness Month: Virginia Tech researchers work toward better treatments
Alzheimer’s disease, a deadly brain disease than can cause loss of memory and mobility, affects millions of lives daily. June marks Alzheimer’s and Brain Awareness Month, and Virginia Tech researchers are engaged in research meant to advance treatment for Alzheimer’s disease and assist caregivers of loved ones with dementia.
Removal of Ovaries Before Menopause Associated With Reduced White Matter in Brain
Women who have their ovaries removed before menopause, particularly before the age of 40, have reduced white matter integrity in multiple regions of the brain later in life.
Common Prostate Drugs Tied to Lower Risk of Dementia with Lewy Bodies
Certain drugs used to treat urinary symptoms due to an enlarged prostate may be associated with a reduced risk of dementia with Lewy bodies, according to a study published in the June 19, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
NUS linguists make breakthrough discovery on detecting early linguistic signs of dementia by studying the natural speech of seniors
A study led by linguists from the NUS Faculty of Arts and Social Sciences has found that early linguistic signs of dementia can be detected through the study of the natural speech of senior Singaporeans. The novel study revealed that participants with memory-related mild cognitive impairment spoke less and used fewer, but more abstract, nouns that is consistent with the speech pattern of Alzheimer’s patients.
Vigorous Exercise May Preserve Cognition in High-Risk Patients With Hypertension
People with high blood pressure have a higher risk of cognitive impairment, including dementia, but a new study from researchers at Wake Forest University School of Medicine suggests that engaging in vigorous physical activity more than once a week can lower that risk.
5-Minute Test Leads to Better Care for People with Dementia in the Primary Care Setting
The underdiagnosis of dementia, especially among Black and Hispanic patients, is a long-standing challenge in medicine.
Healthcare tip sheet: Topics for June & July – Ochsner Health experts available
As you plan for upcoming healthcare coverage in June and July, Ochsner Health has medical experts on standby to the discuss the timely and relevant topics listed below. June: Early signs of dementia you need to know– Dementia is not…
Mount Sinai Experts Present Research at SLEEP 2024
Sleep medicine experts available for interview on breaking and trending news about obstructive sleep apnea, CPAP, and more
Eating More Ultra-processed Foods Tied to Cognitive Decline, Stroke
People who eat more ultra-processed foods like soft drinks, chips and cookies may have a higher risk of having memory and thinking problems and having a stroke than those who eat fewer processed foods, according to a new study published in the May 22, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study does not prove that eating ultra-processed foods causes memory and thinking problems and stroke. It only shows an association.
Scientists aim to stop harmful gut bacteria triggering Alzheimer’s
Australian scientists are exploring how harmful gut bacteria from a poor diet can access the brain and trigger early onset Alzheimer’s disease.
Uniformed Services University Contributes to Groundbreaking Global Study on Multiple System Atrophy
In a groundbreaking study published May 2, 2024 in Neuron, researchers have identified four new genetic risk factors for multiple system atrophy (MSA), shedding light on this poorly understood disorder.
FAU Researchers Receive $1M in FDOH Grants to Fight Alzheimer’s Disease
With this funding, FAU researchers will shed light on the biological functions of Alzheimer’s disease (AD) by taking advantage of synthetic chemistry strategies; provide an innovative online screening tool for older drivers with cognitive decline; and gain a deeper understanding of the role of brain cholesterol in AD.
Innovative Microscopy Demystifies Metabolism of Alzheimer’s
Using state-of-the-art microscopy techniques developed on campus, researchers at UC San Diego School of Medicine have shed new light on the underlying mechanisms driving Alzheimer’s disease.
Scientists identify cell vulnerability ‘fingerprint’ related to Parkinson’s, Lewy body dementia
A new study offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson’s disease and some dementias.
Study Reveals How Obesity Could Accelerate Aging in the Brain
A new study conducted in mice traces how obesity and a high-fat diet may accelerate aging in the blood vessels that supply blood to the brain. The work is being presented this week at the American Physiology Summit, the flagship annual meeting of the American Physiological Society.
Human brains are getting larger. That may be good news for dementia risk
A new study published in JAMA Neurology found human brains are getting bigger. The increased size may lead to a brain reserve, potentially reducing the risk of dementia.
New research at Case Western Reserve University aims to address racial disparities in cognitive decline
According to new research at Case Western Reserve University, connecting with friends is key to limiting social isolation—something researchers believe could also reduce Alzheimer’s, dementia
EXPERT INTERVIEW: Alzheimer’s Association report reveals new Alzheimer’s disease incidence, costs figures and dementia care barriers/challenges
EMBARGOED UNTIL 20 MARCH 2024 On March 20, the Alzheimer’s Association will release its 2024 Alzheimer’s Disease Facts and Figures report, which provides an in-depth look at the latest statistics and information on Alzheimer’s disease prevalence, incidence, mortality, caregiving, dementia care workforce,…
‘Curved’ Walking and a Depth Camera: New Tool Detects Early Cognitive Decline
Gait impairments often are prevalent in the early stages of cognitive decline. Researchers quantitatively compared straight walking and curved walking – a more natural yet complex activity – in healthy older adults and adults with mild cognitive impairment (MCI). A depth camera detected and tracked 25 joints of body movement and signals were processed to extract 50 gait markers. Intriguingly, curved walking illuminated notable disparities between the study groups.
Wrist Device That Monitors Activity Could Help Provide Early Warning of Alzheimer’s
Monitoring daily activity patterns using a wrist-worn device may detect early warning signs of Alzheimer’s disease, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health.
People with Essential Tremor May Have Increased Risk of Dementia
Dementia may be three times more common among people with essential tremor, a movement disorder that causes involuntary shaking, than the general population, according to research released today, March 6, 2024. The study will be presented at the American Academy of Neurology’s 76th Annual Meeting taking place April 13–18, 2024, in person in Denver and online.
Four University of Michigan research teams selected for virtual tournament of science
Four University of Michigan research teams have made the bracket of 64 teams for STAT Madness, a virtual tournament of science. They were picked for their groundbreaking work on brain cancer, heart transplant, dementia care and deadly fungal infections published in 2023.
Doctor discusses a recent study about dementia.
Tresa Mcneal, MD, at Baylor Scott & White Health, discusses a recent study about dementia. What You Need to Know: Dementia affects thinking, memory and social ability. Stroke can cause dementia. Dementia risks increase for those who are sedentary. Reduce…
Study Detects Cognitive Changes in Older Drivers Using In-vehicle Sensors
Continuous, unobtrusive sensors and related monitoring devices are installed in older drivers’ vehicles to detect changes in highly complex activities over time. A driver facing camera, forward facing camera, and telematics unit provide video in real-time to enable researchers to analyze abnormal driving such as getting lost, reaction time and braking patterns as well as travel patterns such as miles driven, miles during the night and daytime, and driving in severe weather. Detecting changes in behavior could generate early warning signs of possible changes in cognition.
Risk of hospital readmission after surgery is high for older Americans
A new Yale study finds an increased risk of hospital readmission for older Americans within 180 days of undergoing major surgery — a risk that is particularly acute for individuals who are frail or have dementia.
AI Finds Key Signs That Predict Patient Survival Across Dementia Types
Researchers at the Icahn School of Medicine at Mount Sinai and others have harnessed the power of machine learning to identify key predictors of mortality in dementia patients. The study, published in the February 28 online issue of Communications Medicine, addresses critical challenges in dementia care by pinpointing patients at high risk of near-term death and uncovers the factors that drive this risk. Unlike previous studies that focused on diagnosing dementia, this research delves into predicting patient prognosis, shedding light on mortality risks and contributing factors in various kinds of dementia.
Researchers make precious headway into a genetic form of Alzheimer’s disease
UC Santa Barbara researchers and collaborators in Colombia, Brazil and Germany are progressing toward an understanding of mechanisms that underlie Alzheimer’s disease, in particular an early-onset, genetic form that has afflicted generations of an extended family in Colombia.
May I have a quick word? Study shows talking faster is linked to better brain health as we age
As we get older, we may start to notice it takes us longer to find the right words. This can lead to concerns about cognitive decline and dementia.
Yoga provides unique cognitive benefits to older women at risk of Alzheimer’s disease, study finds
A new UCLA Health study found Kundalini yoga provided several benefits to cognition and memory for older women at risk of developing Alzheimer’s disease including restoring neural pathways, preventing brain matter decline and reversing aging and inflammation-associated biomarkers – improvements not seen in a group who received standard memory training exercises.
Air Pollution Linked to More Signs of Alzheimer’s in Brain
People with higher exposure to traffic-related air pollution were more likely to have high amounts of amyloid plaques in their brains associated with Alzheimer’s disease after death, according to a study published in the February 21, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Drug Repairs Systems That Drain Alzheimer’s-Causing Waste From Brain, Study Shows
Rutgers study led by undergrads and gap-year students breaks ground in the field of neuroscience and suggests experimental medication could treat dementia.
New genetic therapy holds promise for ALS and frontotemporal dementia
Neuroscientists at Macquarie University in Australia have developed a single-dose genetic medicine that has been proven to halt the progression of both ALS and frontotemporal dementia (FTD) in mice – and may even offer the potential to reverse some of the effects of the fatal diseases.
Podcast: Experts in Health: The menopause and the controversial ‘male menopause’
Professor Eef Hogervorst, Professor of Biological Psychology at Loughborough University, sits down to discuss the factors influencing the menopause, what the best treatment options are, the relationship between oestrogen and dementia, and the controversies surrounding the andropause (the ‘male menopause’).
Dementia Researchers Share Recruitment Strategies for Pragmatic Clinical Trial
The Dementia Care (D-CARE) Study (2019-2023), which was conducted at four clinical trial sites in the U.S., compared three approaches in dementia care. Despite challenges during the COVID-19 pandemic, D-CARE successfully enrolled 2,176 racially/ethnically diverse persons with Alzheimer’s disease or related dementias and their caregivers.
Language barriers could contribute to higher aggression in people with dementia
Immigrants living with dementia were more likely to present with agitation and aggression compared with their non-immigrant counterparts, a new study by Edith Cowan University (ECU) in collaboration with The Dementia Centre, HammondCare, found.
Certain Older Americans Show Hesitation Around Brain Scan Research
Rutgers Health researchers find differences among Asian older adults’ support of research and inclination to receive MRI results.
Dr. Claudia Padilla discusses Alzheimer’s and a new treatment.
Claudia Padilla, MD, at Baylor Scott & White Health, discusses Alzheimer’s and a new treatment. What You Need to Know: Alzheimer’s disease is a type of dementia. The most common sign is short-term memory loss. New medication targets the protein…
The Medical Minute: Hearing impairment can lead to depression, isolation, dementia
Left unchecked, hearing loss can lead to lead to social isolation and depression – two conditions proven to hasten dementia. A Penn State Health expert sounds off on what you can do about it.
Residents of Rural ‘Glades’ Take a ‘Leap of Faith’ to Combat Dementia
Compared to urban dwellers, racially/ethnically diverse older adults face up to an 80 percent greater risk of cognitive impairment in older age, and 2.5 times potentially preventable Alzheimer’s-related (ADRD) hospitalizations.
Vaccines May Protect Against Alzheimer’s, But How? Asks Domenico Praticò, MD, FCPP
Commonly used vaccines may also protect against dementia, according to a recent paper published in the Journal of Alzheimer’s Disease [J. Alzheimer’s Disease 2023; 95(2): 703–718)]. The authors found that after receiving the tetanus/diphtheria vaccine and whooping cough (aka, pertussis)…