White Blood Cell Changes Develop in Acute Kidney Injury, Regardless of Cause

Article title: Distinct developmental reprogramming footprint of macrophages during acute kidney injury across species Authors: Michal Mrug, Elias Mrug, Frida Rosenblum, Jiandong Chen, Xiangqin Cui, Anupam Agarwal, Abolfazl Zarjou From the authors: “Our findings identify robust acute kidney injury (AKI)-induced…

Men with Chronic Kidney Disease Have Higher Resting Activity in ‘Fight-or-Flight’ System than Women

Article title: Sex differences in sympathetic activity and vascular stiffness in adults with chronic kidney disease (CKD) Authors: Matias G. Zanuzzi, Jinhee Jeong, Dana R. DaCosta, Jeanie Park From the authors: “We show for the first time that males with…

Exercise Testing Uncovers Cardiovascular Disease Risk Factor in Black Postmenopausal Women

Article title: Exercise testing unmasks exaggerated blood pressure independent of fibrinolytic response in Black but not White postmenopausal females Authors: João L. Marôco, Linda M Szymanski, Tracy Baynard, Bo Fernhall From the authors: “Our findings show that maximal exercise unmasks…

Timing of Both Fasting and Meals Affects Degree of DNA Damage to Small Intestine Caused by Chemotherapy

Article title: Mechanisms driving fasting-induced protection from genotoxic injury in the small intestine Authors: Kali Deans-Fielder, Timothy Wu, Thanh Nguyen, Sarah To, Yang-Zhe Huang, Steven J. Bark, Jason C. Mills, Noah F. Shroyer From the authors: “Our results also showed…

Study Reveals How Obesity Could Accelerate Aging in the Brain

A new study conducted in mice traces how obesity and a high-fat diet may accelerate aging in the blood vessels that supply blood to the brain. The work is being presented this week at the American Physiology Summit, the flagship annual meeting of the American Physiological Society.

Acetaminophen May Be Less Heart-safe than Previously Thought

The common painkiller acetaminophen was found to alter proteins in the heart tissue when used regularly at moderate doses, according to a new study conducted in mice. Researchers will present their work this week at the American Physiology Summit in Long Beach, California.

Short On Time? A 15-minute Workout May Help Boost Your Immune System 

Exercising at moderate intensity for just 15 minutes may be all that is needed to boost immunity by increasing levels of natural killer (NK) cells. Researchers will present their work this week at the American Physiology Summit in Long Beach, California.

Heavy Alcohol Use May Increase Type 2 Diabetes Risk in Middle-aged Adults

Heavy alcohol use may increase middle-aged adults’ risk of developing Type 2 diabetes, according to research to be presented this week at the American Physiology Summit in Long Beach, California. The Summit is the flagship annual meeting of the American Physiological Society (APS).

Study Bolsters Evidence that Effects of Puberty Blockers Are Reversible

Medications commonly known as puberty blockers were found to delay development of female reproductive organs but allow for restoration of reproductive functioning after the medications were withdrawn, according to a new study being presented this week at the American Physiology Summit.

Intermittent Fasting May Help Preserve Intestinal Health as We Age

A study in mice found that intermittent fasting brought benefits beyond weight loss, suggesting it could help the body better process glucose and reduce age-related declines in intestinal function. Researchers will present their work this week at the American Physiology Summit.

Prebiotics Could Help Space Travelers Stay Healthy

New research suggests that cultivating a healthy gut microbiome could help astronauts weather the stresses of altered gravity. Researchers will present their work this week at the American Physiology Summit, the flagship annual meeting of the American Physiological Society, in Long Beach, California

Resistant Starch Could Help Combat Leading Cause of End-stage Kidney Failure

Combining a low dose of blood pressure medication with a higher intake of dietary-resistant starch might help stave off diabetic kidney disease, according to results from a new animal study. Researchers will present their work this week at the American Physiology Summit.

American Physiological Society Announces 2024 Award Recipients

The American Physiological Society (APS) is pleased to announce the recipients of the Society’s most prestigious and highly competitive awards. Awardees will be recognized for their achievements at the American Physiology Summit, APS’ flagship annual meeting, to be held April 4–7, 2024, in Long Beach, California.

Older Adults Show Greater Increase in Body Temperature in Simulated Heatwave Than Previously Reported

Under conditions designed to better mirror real-world conditions, a new study finds that adults 65 and older are affected more by heatwave-like temperatures than previously reported. The study included intermittent bouts of light activity and was published in the Journal of Applied Physiology.

Mitochondrial Changes Linked to High Blood Pressure in Pregnancy

A new study provides evidence for the possibility that mitochondrial dysregulation could be a contributing factor in the development of hypertensive disorders of pregnancy. The study is published in Physiological Genomics. It was chosen as an APSselect article for July.

Women with Long COVID May Develop High Blood Pressure

New research identifies parts of the cardiovascular system that are disrupted by long COVID. The study is published in the American Journal of Physiology-Heart and Circulatory Physiology and was chosen as an APSselect article for June.

Climate Change Threatens Military Readiness

The growing frequency and intensity of heat waves around the globe pose “a substantial, persistent ‘non-combat threat’” to military training and operations, according to experts in environmental, thermoregulatory and cardiovascular physiology.

Blood Flow-restricted Resistance Exercise Could Help Counteract Age-related Muscle Loss

Low-load blood flow-restricted resistance exercise helped counter age-related muscle decay “with a modest exercise volume and in a very time-efficient manner.” The study is published ahead of print in the Journal of Applied Physiology. It was chosen as an APSselect article for May.

New APS Leaders Take Office at Inaugural American Physiology Summit

The American Physiological Society (APS) is pleased to announce its new member leaders for 2023–24: President Willis K. “Rick” Samson, PhD, DSc, FAPS; President-elect Timothy Musch, PhD, FAPS, FACSM; and Councilors Michael Caplan, MD, PhD, FAPS; Karla Haack, PhD; and Gina Yosten, PhD. The new officers were elected by APS membership and took office April 23, 2023, at the American Physiology Summit, APS’ flagship annual meeting, in Long Beach, California.

American Physiological Society Announces 2023 Award Recipients

The American Physiological Society (APS) is pleased to announce the recipients of the Society’s most prestigious and highly competitive awards. Awardees will be recognized for their achievements at the American Physiology Summit, APS’ flagship annual meeting, to be held April 20–23, 2023, in Long Beach, California.

Personalized Exercise Program Improves Long COVID Symptoms

A supervised, eight-week exercise program improved symptoms of patients with long COVID better than the current standard self-managed rehabilitation recommendations. The study is published ahead of print in the Journal of Applied Physiology and was chosen as an APSselect article for February.

Vitamin A May Protect Heart from Some Effects of Obesity

Research in a mouse model of diet-induced obesity found greater disruption to genes involved in heart function when coupled with vitamin A deficiency. The study is published in the American Journal of Physiology-Heart and Circulatory Physiology. It was chosen as an APSselect article for January.

Boosting Omega-3 Production Could Help Cut Chronic Inflammation and Fatty Liver Disease

Rockville, Md. (January 25, 2022)—A new study from researchers at Laval University in Quebec, Canada, shows that genetically increasing omega-3 fatty acid production, without direct gut microbiota contact, improves the balance of insulin and glucagon (glucose balance) in obese mice.…

Gender Affirmation Treatment Delivery Route May Affect Heart Health

Transgender and gender diverse (TGD) people assigned male at birth are at increased heart health risk. The delivery route of estrogen medication is known to affect heart health risk in cisgender women. However, research is lacking on how estrogen route affects heart health in the TGD population.

APS Porter Physiology Development Fellowship Honored with an Association Impact Award

The American Physiological Society’s (APS) Porter Physiology Development Fellowship, the Society’s flagship diversity program, has been honored with an inaugural Impact Award from the Software & Information Industry Association’s (SIIA) Associations, Media and Publishing (AM&P) Network.

Oil Spill Effects on Mahi-mahi Go Far Beyond Initial Survival

New research into oil spills’ effects finds surviving the initial event does not guarantee success for the popular sport fish mahi-mahi (Coryphaena hippurus). Exposed fish faced temporary increased predation and did not spawn for the entire observation time.

Climate Change Double Whammy Causes Unexpected Effects in Pacific Mussels

Comparative physiologists studied how two aspects of climate change—warming temperatures and increasingly acidic waters—may affect the ecologically important Pacific blue mussel (Mytilus trossulus), a foundational species in the intertidal environments of the northern Pacific Ocean.

Vitamin B5 May Help Weight Loss by Turning on Brown Fat

Pantothenate acid, also known as vitamin B5, stimulated the production of brown fat in both cell cultures and mice, a new study finds. “[B5] has therapeutic potential for treating obesity and type II diabetes,” researchers conclude. The study was chosen as an APSselect article for July.

Common Prebiotic Fiber Mitigates Harm of High-salt Diet in Rats

New research in rats finds a diet high in the fiber inulin offered a protective effect against the damage of a high-salt diet. The research will be presented this week at the American Physiological Society and American Society for Nephrology Control of Renal Function in Health and Disease conference

Intermittent Fasting Protects Kidneys of Obese Mice

New research in mice finds that time-restricted feeding improves markers of kidney and vascular health. The research will be presented this week at the American Physiological Society and American Society for Nephrology Control of Renal Function in Health and Disease conference.

Researchers Identify Potential Target for Treating Autoimmune Diseases

New research using a mouse model for multiple sclerosis has uncovered a potential new area to explore for possible treatments for autoimmune disorders.

High Caffeine Consumption Disrupts Heart Rhythms in Middle-aged Rats

New research finds that excess caffeine is more likely to cause irregular heart rhythms in middle aged rats than in young adult rats. The study will be presented this week at the American Physiological Society annual meeting at Experimental Biology 2022 in Philadelphia.

Five Minutes of Daily Breath Training Improves Exercise Tolerance in Middle-aged and Older Adults

New research finds potential for high-resistance inspiratory muscle strength training to help sedentary middle-aged and older adults transition to a healthier lifestyle. The study will be presented this week at the American Physiological Society annual meeting at Experimental Biology 2022.

Exercise Improves Health Markers in Young Female Survivors of Childhood Trauma

New research shows a progressive exercise training program mitigates some physiological and psychological effects of adverse childhood experiences in otherwise healthy young women. The study will be presented at the American Physiological Society annual meeting at Experimental Biology 2022.

New APS Leaders Take Office for Coming Year

The American Physiological Society (APS) is pleased to announce its new leadership: President Jennifer Pollock, PhD, FAPS, FAHA; President-elect Dee U. Silverthorn, PhD, FAPS, FAAA, FAAAS; and Councilors Lacy Alexander, PhD, FACSM; Margarita Curras-Collazo, PhD, FAPS; and Dexter Lee, PhD. The new officers were elected by APS membership and took office April 30, 2021.