Nearly 1 in 7 Americans experience bloating on a weekly basis, and most aren’t seeking professional care for it, according to a new study led by Cedars-Sinai investigators. The findings are published in Clinical Gastroenterology and Hepatology.
Tag: Ulcerative Colitis
Can Butyrate Help Hispanic Children With Ulcerative Colitis?
New study is the first of its kind to focus on Hispanic children, who often have more severe disease. A novel clinical trial at Children’s Hospital Los Angeles is investigating whether butyrate—a short-chain fatty acid typically produced by gut bacteria—can be a potential therapy for children with ulcerative colitis.
Mount Sinai Study Uncovers Mechanisms of Reactive Oxygen Species in Stem Cell Function and Inflammation Prevention
Mount Sinai researchers have published one of the first studies to demonstrate the importance of reactive oxygen species in maintaining stem cell function and preventing inflammation during wound repair, which could provide greater insights into the prevention and treatment of inflammatory bowel diseases (IBD), according to findings published in the journal Gut on October 3.
New Gastroparesis Clinical Guideline Featured in August Issue of AJG
The August issue of The American Journal of Gastroenterology highlights new clinical science, including a brand new ACG clinical guideline for the diagnosis and treatment of patients with gastroparesis.
Holistic Approach to Treatment of Ulcerative Colitis
About 1 million people in the US suffer from ulcerative colitis, an inflammatory bowl disease that causes inflammation and sores in the digestive tract. Dr. Oleg Shulik worked with a patient to develop a holistic approach to treatment that allowed her to stop taking medications to manage her symptoms.
Surgery to Heal Inflamed Gut May Create New Target for Disease
A surgical procedure meant to counter ulcerative colitis, an immune disease affecting the colon, may trigger a second immune system attack, a new study shows.
Multi-Population Risk Scores Could Improve Risk Prediction for Inflammatory Bowel Diseases, Study Finds
New study illustrates how studying diverse populations can help predict patient outcomes and reduce health disparities
NYU, Columbia, and Takeda Form Research Alliance for Gastrointestinal and Liver Disorders
New York University, Columbia University, and Takeda Pharmaceutical Company Limited (“Takeda”) have formed a collaborative research alliance to begin and advance gastroenterology research programs, with the goal of developing new therapies for patients with gastrointestinal and liver disorders.

Genetic Risk for Fatal Blood Clots Identified in IBD Patients
Blood clots are the biggest cause of death in patients with inflammatory bowel disease (IBD) ─ ulcerative colitis or Crohn’s disease. In a retrospective study recently published in the journal Gastroenterology, Cedars-Sinai investigators found that a combination of rare and common genetic variants in some IBD patients significantly increased their risk of developing clot-causing thromboembolic diseases.

Inflammatory Bowel Disease Linked to an Immune Cell Run Amok
Researchers at UC San Diego School of Medicine report that the lasting nature of inflammatory bowel disease may be due to a type of long-lived immune cell that can provoke persistent, damaging inflammation in the intestinal tract.

University of Miami Study Finds Dietary Changes May Help People with Ulcerative Colitis
A new study published in Clinical Gastroenterology and Hepatology led by Maria T. Abreu, M.D., professor of medicine and professor of microbiology and immunology at the University of Miami Miller School of Medicine, found that eating diets low in fat and high in fiber may improve the quality of life of patients with ulcerative colitis (UC) — even those in remission.

$6M, 5-year NIH grant extends funding for collaborative Cleveland Digestive Diseases Research Core Center
A new $6 million, 5-year grant from the National Institutes of Health extends funding for the Silvio O. Conte Cleveland Digestive Diseases Research Core Center (DDRCC), a cross-institutional collaboration of digestive disease investigators.
Mount Sinai Researchers Unveil Mechanisms to Prevent Crohn’s Disease and First Study Linking Metals Exposure w/ IBD
In a series of four studies published today in Gastroenterology, a journal of the American Gastroenterological Association, Mount Sinai inflammatory bowel disease (IBD) researchers, describe the identification of predictive tools and a new understanding of environmental factors that trigger IBD.

Case Western Reserve University researchers discover critical link to controlling inflammation in Crohn’s disease
Investigators at the Case Western Reserve University School of Medicine discovered that blocking interleukin-1α (IL1α), a protein that controls inflammation in the gut, markedly decreases the severity of intestinal inflammation in a mouse model of Crohn’s disease (CD).