Investigators at Cedars-Sinai have identified risk factors that make inflammatory bowel disease (IBD) patients susceptible to developing serious conditions in other parts of their bodies.
Tag: Ulcerative Colitis
Body changes up to eight years before inflammatory bowel disease diagnosis
Researchers at the Francis Crick Institute and Aalborg University in Copenhagen have shown that changes can be detected in blood tests up to eight years before a diagnosis of Crohn’s disease and up to three years before a diagnosis of ulcerative colitis.
FDA Approves Mirikizumab, a Promising Induction and Maintenance Therapy for Ulcerative Colitis
Offers new option with improved quality of life for patients with moderate-to-severely active disease.
Inflammatory Bowel Disease Linked to Atopic Dermatitis, Penn Medicine Research Finds
Adults with atopic dermatitis (AD) have a 34 percent increased risk of developing new-onset inflammatory bowel disease (IBD) compared with individuals who do not have the skin condition, and children have a 44 percent increased risk, according to a new study from the Perelman School of Medicine at the University of Pennsylvania.
Mayo Clinic researchers link environmental exposures to liver disease
Mayo Clinic researchers have identified a diverse range of environmental chemicals in human bile in patients with primary sclerosing cholangitis, a rare, chronic liver disease of the bile ducts. The study, published in Exposome, represents a new frontier of research at Mayo Clinic’s Center for Individualized Medicine that explores the exposome, the measure of environmental contributors to disease and health.
May Issue of AJG Features Colonoscopy Quality and Bowel Prep, CME on Social Media
The May issue of AJG features new clinical science and reviews, including bowel prep recommendations for physicians, longer withdrawal times for screening colonoscopy, the use of social media for continuing medical education, and tofacitinib de-escalation and re-escalation for ulcerative colitis.
Study to decode microbe-gut signaling suggests potential new treatment for IBD
Fresh insights into how our bodies interact with the microbes living in our guts suggest that a two-drug combination may offer a new way to treat inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis.
UChicago Medicine trains physicians on ‘game-changing’ intestinal ultrasound
UChicago Medicine is the only hospital in the Midwest, and one of just two nationwide, to offer intestinal ultrasound to patients.
Psyllium fiber protects against colitis by activating bile acid sensor, biomedical sciences researchers find
Psyllium fiber protects against ulcerative colitis and suppresses inflammation by activating the bile acid nuclear receptor, a mechanism that was previously unrecognized, according to a new study by researchers in the Institute for Biomedical Sciences at Georgia State University.
Bloating Common Issue Among Americans, Study Reports
Nearly 1 in 7 Americans experience bloating on a weekly basis, and most aren’t seeking professional care for it, according to a new study led by Cedars-Sinai investigators. The findings are published in Clinical Gastroenterology and Hepatology.
Can Butyrate Help Hispanic Children With Ulcerative Colitis?
New study is the first of its kind to focus on Hispanic children, who often have more severe disease. A novel clinical trial at Children’s Hospital Los Angeles is investigating whether butyrate—a short-chain fatty acid typically produced by gut bacteria—can be a potential therapy for children with ulcerative colitis.
Mount Sinai Study Uncovers Mechanisms of Reactive Oxygen Species in Stem Cell Function and Inflammation Prevention
Mount Sinai researchers have published one of the first studies to demonstrate the importance of reactive oxygen species in maintaining stem cell function and preventing inflammation during wound repair, which could provide greater insights into the prevention and treatment of inflammatory bowel diseases (IBD), according to findings published in the journal Gut on October 3.
New Gastroparesis Clinical Guideline Featured in August Issue of AJG
The August issue of The American Journal of Gastroenterology highlights new clinical science, including a brand new ACG clinical guideline for the diagnosis and treatment of patients with gastroparesis.
Holistic Approach to Treatment of Ulcerative Colitis
About 1 million people in the US suffer from ulcerative colitis, an inflammatory bowl disease that causes inflammation and sores in the digestive tract. Dr. Oleg Shulik worked with a patient to develop a holistic approach to treatment that allowed her to stop taking medications to manage her symptoms.
Surgery to Heal Inflamed Gut May Create New Target for Disease
A surgical procedure meant to counter ulcerative colitis, an immune disease affecting the colon, may trigger a second immune system attack, a new study shows.
Multi-Population Risk Scores Could Improve Risk Prediction for Inflammatory Bowel Diseases, Study Finds
New study illustrates how studying diverse populations can help predict patient outcomes and reduce health disparities
NYU, Columbia, and Takeda Form Research Alliance for Gastrointestinal and Liver Disorders
New York University, Columbia University, and Takeda Pharmaceutical Company Limited (“Takeda”) have formed a collaborative research alliance to begin and advance gastroenterology research programs, with the goal of developing new therapies for patients with gastrointestinal and liver disorders.
Genetic Risk for Fatal Blood Clots Identified in IBD Patients
Blood clots are the biggest cause of death in patients with inflammatory bowel disease (IBD) ─ ulcerative colitis or Crohn’s disease. In a retrospective study recently published in the journal Gastroenterology, Cedars-Sinai investigators found that a combination of rare and common genetic variants in some IBD patients significantly increased their risk of developing clot-causing thromboembolic diseases.
Inflammatory Bowel Disease Linked to an Immune Cell Run Amok
Researchers at UC San Diego School of Medicine report that the lasting nature of inflammatory bowel disease may be due to a type of long-lived immune cell that can provoke persistent, damaging inflammation in the intestinal tract.
University of Miami Study Finds Dietary Changes May Help People with Ulcerative Colitis
A new study published in Clinical Gastroenterology and Hepatology led by Maria T. Abreu, M.D., professor of medicine and professor of microbiology and immunology at the University of Miami Miller School of Medicine, found that eating diets low in fat and high in fiber may improve the quality of life of patients with ulcerative colitis (UC) — even those in remission.
$6M, 5-year NIH grant extends funding for collaborative Cleveland Digestive Diseases Research Core Center
A new $6 million, 5-year grant from the National Institutes of Health extends funding for the Silvio O. Conte Cleveland Digestive Diseases Research Core Center (DDRCC), a cross-institutional collaboration of digestive disease investigators.
Mount Sinai Researchers Unveil Mechanisms to Prevent Crohn’s Disease and First Study Linking Metals Exposure w/ IBD
In a series of four studies published today in Gastroenterology, a journal of the American Gastroenterological Association, Mount Sinai inflammatory bowel disease (IBD) researchers, describe the identification of predictive tools and a new understanding of environmental factors that trigger IBD.
Case Western Reserve University researchers discover critical link to controlling inflammation in Crohn’s disease
Investigators at the Case Western Reserve University School of Medicine discovered that blocking interleukin-1α (IL1α), a protein that controls inflammation in the gut, markedly decreases the severity of intestinal inflammation in a mouse model of Crohn’s disease (CD).