Article title: Distinct developmental reprogramming footprint of macrophages during acute kidney injury across species Authors: Michal Mrug, Elias Mrug, Frida Rosenblum, Jiandong Chen, Xiangqin Cui, Anupam Agarwal, Abolfazl Zarjou From the authors: “Our findings identify robust acute kidney injury (AKI)-induced…
Tag: APSselect
Men with Chronic Kidney Disease Have Higher Resting Activity in ‘Fight-or-Flight’ System than Women
Article title: Sex differences in sympathetic activity and vascular stiffness in adults with chronic kidney disease (CKD) Authors: Matias G. Zanuzzi, Jinhee Jeong, Dana R. DaCosta, Jeanie Park From the authors: “We show for the first time that males with…
Exercise Testing Uncovers Cardiovascular Disease Risk Factor in Black Postmenopausal Women
Article title: Exercise testing unmasks exaggerated blood pressure independent of fibrinolytic response in Black but not White postmenopausal females Authors: João L. Marôco, Linda M Szymanski, Tracy Baynard, Bo Fernhall From the authors: “Our findings show that maximal exercise unmasks…
Routinely Wearing High Heels Reduces Energy Cost of Walking, Even Out of Heels
Article title: Habitually wearing high heels may improve user walking economy in any footwear Authors: Owen N. Beck, Jordyn N. Schroeder, Gregory S. Sawicki From the authors: “Habitually wearing high-heeled footwear structurally remodels leg muscle tendons and improves user walking…
Timing of Both Fasting and Meals Affects Degree of DNA Damage to Small Intestine Caused by Chemotherapy
Article title: Mechanisms driving fasting-induced protection from genotoxic injury in the small intestine Authors: Kali Deans-Fielder, Timothy Wu, Thanh Nguyen, Sarah To, Yang-Zhe Huang, Steven J. Bark, Jason C. Mills, Noah F. Shroyer From the authors: “Our results also showed…
High-intensity Aerobic Exercise Helps Prevent Menopause-related Muscle Power Loss
Menopause causes a decrease in “muscle power,” an indication of muscle function and strength. However, postmenopausal loss of muscle power can be partially prevented by using high-intensity interval training (HIIT), a form of aerobic exercise.
Older Adults Show Greater Increase in Body Temperature in Simulated Heatwave Than Previously Reported
Under conditions designed to better mirror real-world conditions, a new study finds that adults 65 and older are affected more by heatwave-like temperatures than previously reported. The study included intermittent bouts of light activity and was published in the Journal of Applied Physiology.
Mitochondrial Changes Linked to High Blood Pressure in Pregnancy
A new study provides evidence for the possibility that mitochondrial dysregulation could be a contributing factor in the development of hypertensive disorders of pregnancy. The study is published in Physiological Genomics. It was chosen as an APSselect article for July.
Women with Long COVID May Develop High Blood Pressure
New research identifies parts of the cardiovascular system that are disrupted by long COVID. The study is published in the American Journal of Physiology-Heart and Circulatory Physiology and was chosen as an APSselect article for June.
Blood Flow-restricted Resistance Exercise Could Help Counteract Age-related Muscle Loss
Low-load blood flow-restricted resistance exercise helped counter age-related muscle decay “with a modest exercise volume and in a very time-efficient manner.” The study is published ahead of print in the Journal of Applied Physiology. It was chosen as an APSselect article for May.
Vitamin A May Protect Heart from Some Effects of Obesity
Research in a mouse model of diet-induced obesity found greater disruption to genes involved in heart function when coupled with vitamin A deficiency. The study is published in the American Journal of Physiology-Heart and Circulatory Physiology. It was chosen as an APSselect article for January.
Gender Affirmation Treatment Delivery Route May Affect Heart Health
Transgender and gender diverse (TGD) people assigned male at birth are at increased heart health risk. The delivery route of estrogen medication is known to affect heart health risk in cisgender women. However, research is lacking on how estrogen route affects heart health in the TGD population.
Short ‘Activity Snacks’ Help Maintain Muscle Mass
Interrupting prolonged sitting with periodic “activity snacks” may help maintain muscle mass and quality, according to researchers at the University of Toronto in Canada.
Inhaling Silica Particles May Cause Kidney Disease
New research in rats demonstrates that inhaling amorphous silica particles—of the size released from burning sugarcane—could damage the kidneys. The study, chosen as an APSselect for August, is published ahead of print in the American Journal of Physiology-Renal Physiology.
Vitamin B5 May Help Weight Loss by Turning on Brown Fat
Pantothenate acid, also known as vitamin B5, stimulated the production of brown fat in both cell cultures and mice, a new study finds. “[B5] has therapeutic potential for treating obesity and type II diabetes,” researchers conclude. The study was chosen as an APSselect article for July.
Researchers Identify Potential Target for Treating Autoimmune Diseases
New research using a mouse model for multiple sclerosis has uncovered a potential new area to explore for possible treatments for autoimmune disorders.