Scientists have demonstrated that normal brain aging is accelerated by approximately 26% in people with progressive type 2 diabetes compared with individuals without the disease, reports a study published today in eLife.
The Icahn School of Medicine at Mount Sinai has launched a new research center devoted to understanding how epigenomics influences the nervous system under both healthy and disease conditions. The Center for Neural Epigenome Engineering aims to dramatically expand Mount Sinai’s ability to conduct research in this field, facilitating new discoveries and the development of long-sought treatments for a variety of neurological and psychiatric disorders. Areas of expansion include chromatin biochemistry, chemical biology, protein engineering, and single-cell “omics.”
Thanks to over a century of modern neuroscience, we have made significant strides in our understanding of the brain.
Some treatments or preventive therapies used to manage intracerebral hemorrhages (ICH), or a bleeding stroke, are not as effective as previously believed, according to the new American Heart Association/American Stroke Association guideline for caring for people with spontaneous ICH, published today in the Association’s Stroke journal. Guidelines detail the latest, evidence-based treatment recommendations and are the Association’s official clinical practice recommendations.
First-of-its-kind study by Rutgers associates some types of shunts used after epilepsy surgery with brains shifting toward the side of the skull.
Researchers at Tel Aviv University, and the University of Naples, have examined the mass extinction of large animals over the past tens of thousands of years and found that extinct species had, on average, much smaller brains than species that survived.
Long-duration space flight alters fluid-filled spaces along veins and arteries in the brain, according to new research from Oregon Health & Science University and scientists across the country.
Stimulation of certain cerebellar areas could help combat absence seizures.
Henry Ford Medical Center – Brownstown has earned an Acute Stroke Ready Hospital advanced stroke certification from The Joint Commission, making it the first freestanding Emergency Room in the State of Michigan to do so, and Henry Ford Macomb Hospital has earned recertification as a Primary Stroke Center.
When it comes to weight loss, the old adage it’s all in your head may be true.
Scientists at Wake Forest University School of Medicine have shown that two specific networks in the brain can strongly influence how successful a person will be when trying to lose weight.
Researchers at Tufts University School of Medicine have discovered a previously unknown function performed by a type of cell that comprises nearly half of all cells in the brain.
The scientists say this discovery in mice of a new function by cells known as astrocytes opens a whole new direction for neuroscience research that might one day lead to treatments for many disorders ranging from epilepsy to Alzheimer’s to traumatic brain injury.
In an article published today in Scientific Reports (https://www.nature.com/articles/s41598-022-10466-8), researchers from Bar-Ilan University in Israel reveal that the brain learns completely differently than has been assumed since the 20th century. The new experimental observations suggest that learning is mainly performed in neuronal dendritic trees, where the trunk and branches of the tree modify their strength, as opposed to modifying solely the strength of the synapses (dendritic leaves), as was previously thought. These observations also indicate that the neuron is actually a much more complex, dynamic and computational element than a binary element that can fire or not. Just one single neuron can realize deep learning algorithms, which previously required an artificial complex network consisting of thousands of connected neurons and synapses. The new demonstration of efficient learning on dendritic trees calls for new approaches in brain research, as well as for the generation
Scientists at UC San Diego School of Medicine and Rady Children’s Institute of Genomic Medicine describe novel methods for inferring the movement of human brain cells during fetal development by studying healthy adult individuals who have recently passed away from natural causes.
New study demonstrates that in utero exposure to mother’s antiepileptic or antidepressant medication may affect development of the newborn brain networks.
Researchers have uncovered new information about how the area of the brain responsible for memory is triggered when the eyes come to rest on a face versus another object or image.
Despite the perception that marijuana is harmless, there is some scientific evidence challenging that belief, and there are many unanswered questions about its impact on brain health, according to a new American Heart Association scientific statement published today in the Association’s journal Stroke.
A new study is showing how value choices are recorded in our brains. Researchers found that persistency allows value signals to be most effectively represented, or “coded,” across different areas of the brain, especially in a critical area within the cerebrum known as the retrosplenial cortex.
The outcome predictive models were developed in part using data from a large multi-center National Institute of Mental Health-funded study and published in the journal Biological Psychiatry. The findings provide strong evidence that the current trial-and-error approach used in clinical practice for the selection of the right antidepressant can be replaced with this new precision medicine approach.
A new discovery of a physiological mechanism of psychosomatic illnesses could open a new therapeutic avenue for treating chronic inflammatory conditions such as Crohn’s disease, psoriasis, and other autoimmune conditions, by attenuating their memory trace in the brain.
Article title: Spectral changes following resective epilepsy surgery and neurocognitive function in children with epilepsy Authors: Olivia N. Arski, Simeon Wong, Nebras M. Warsi, Daniel J. Martire, Ayako Ochi, Hiroshi Otsubo, Elizabeth Donner, Puneet Jain, Elizabeth N. Kerr, Mary Lou…
Humans are able to think a few steps ahead in non-social situations, such as navigating a new hiking trail or planning a vacation. A Mount Sinai study now shows that we may also do this when interacting with other people.
A five-year, $2.59 million grant from the National Institutes of Health will allow a psychology professor at Binghamton University, State University of New York to study the mechanisms of addiction.
Johns Hopkins Medicine is one of three research institutions with scientists awarded $8.9 million to study the growing body of evidence that Parkinson’s disease originates among cells in the gut and travels up the body’s neurons to the brain. The research aims to develop treatments to prevent or halt progression of the disease.
Sexual conflict in fruit flies is governed by specifically wired neurons in the brain which have been pinpointed by scientists at the University of Birmingham, UK.
A new study has measured for the first time a link between variations in size of the brain’s arteries and the likelihood of a cerebral aneurysm, providing scientists with a new screening tool to monitor people at risk.
Our subjective experience appears to us in a continuous stream of integrated information, and in Chaos, researchers explore the question: Which characteristics should brain activity have to support this type of conscious experiences?
For millions of people with epilepsy and movement disorders such as Parkinson’s disease, electrical stimulation of the brain already is widening treatment possibilities. In the future, electrical stimulation may help people with psychiatric illness and direct brain injuries, such as stroke.
Research conducted at the University of Kentucky College of Medicine suggests that higher intake of specific nutrients is associated with lower brain iron concentration and better cognitive performance in older adults.
In a study of rodents, scientists at the Icahn School of Medicine at Mount Sinai discovered that a part of the brain traditionally thought to control typing the old habits may also play a critical role in learning the new actions. The results, published on August 25th in Nature Communications, suggest that this process involves a delicate balance in the activity of two neighboring neural circuits: one dedicated to new actions and the other to old habits
Binghamton University faculty will lead a $587,853 National Science Foundation project examining how brain folds form.
Diclofenac and other NSAIDs may limit the passage of narcolepsy medication and illicit party drug GHB to the brain, decreasing the potential for fatal overdose, University at Buffalo researchers find.
Just eight weeks of meditation studies can make your brain quicker, according to new research from Binghamton University, State University of New York.
Because there is no ethical way to extract brain tissue from patients to look for clues about how amyloid plaques and protein aggregates proliferate, supplementary techniques are needed to better understand the progression of Alzheimer’s disease. During ACA’s 71st annual meeting, Abdullah Al Bashit, from Northeastern University, will discuss using computational techniques to help address these challenges. His work demonstrates how using small and wide-angle scattering along with state-of-the-art detection techniques will help probe the molecular structure and proliferation.
Imagining a song triggers similar brain activity as moments of silence in music, according to a pair of just-published studies in the Journal of Neuroscience.
UC San Diego researchers and their colleagues have discovered that spontaneous impulses of dopamine, the neurological messenger known as the brain’s “feel good” chemical, occur in the brain of mice. The study found that mice can willfully manipulate these random dopamine pulses for reward.
An expanded collaboration between APL and the Amazon Web Services’ Open Data Sponsorship Program will further enable the storage and accessibility of ever-expanding neuroimaging datasets generated by the neuroscience research community.
It’s a favourite first-order for the day, but while a quick coffee may perk us up, new research from the University of South Australia shows that too much could be dragging us down, especially when it comes to brain health.
University of Maryland School of Medicine and University of Vermont researchers have shown how the brain communicates to blood vessels when in need of energy, and how these blood vessels respond by relaxing or constricting to direct blood flow to specific brain regions.
Like a mystery detective, Sara G.M. Piccirillo, PhD, is hunting deadly bad actors by studying the crime scene and questioning bystanders one by one. But these bad actors are cells in the brain. She is using two grants to study tumor cells and cells in the surrounding area, one by one.
Research in mice reveals how a subset of highly specialized immune cells modulate brain wiring by precision-targeting inhibitory synapses.
The work deepens understanding of the versatile repertoire of microglia, the brain’s immune cells and resident garbage collectors.
The results set the stage for the development of therapies for neurodevelopmental and psychiatric conditions marked by defects in synaptic function.
Researchers at the University of Chicago and the U.S. Department of Energy’s (DOE) Argonne National Laboratory have leveraged existing advanced X-ray microscopy techniques to bridge the gap between MRI (magnetic resonance imaging) and electron microscopy imaging, providing a viable pipeline for multiscale whole brain imaging within the same brain
Last year’s lockdowns confined most people to their homes. For teenagers on summer break, a season usually dedicated to recreation and outdoor exploration, this meant long days of boredom. But for Nikhita Kaushik, who just finished her sophomore year at Irvine’s Arnold O. Beckman High School, the free time was a blessing. It enabled her to dive into her passion for neuroscience and establish the Southern California Youth Neuroscience Association.
Irvine, Calif., June 21, 2021 — A large-scale meta-analysis led by University of California, Irvine researchers provides the strongest evidence yet of which blood pressure medications help slow memory loss in older adults: those that can travel out of blood vessels and directly into the brain. The findings, published in the American Heart Association journal Hypertension, will be of interest to the 91 million Americans whose blood pressure is high enough to warrant medication, as well as the doctors who treat them.
Links between lipid imbalance and disease have been established, in which lipid changes increase the formation of amyloid plaques, a hallmark of Alzheimer’s disease. This imbalance inspired researchers to explore the role of lipids comprising the cellular membranes of brain cells. In Biointerphases, the researchers report on the significant role lipids may play in regulating C99, a protein within the amyloid pathway, and disease progression.
A new discovery finds that zinc plays a critical and underappreciated role in blood pressure regulation, offering a potential new pathway for therapies to treat hypertension.
A world-first international study led by the University of South Australia has identified a new drug to stop athletes developing dementia after sustaining repeated head injuries in their career.
The T. Denny Sanford Institute for Empathy and Compassion has opened its newest center, focused on addressing issues of social justice in health care.
Research from Washington University in St. Louis reveals an underlying mechanism for how pauses allow neurons in the midbrain to recover from stimulation.
Thin-film electrodes developed at Lawrence Livermore National Laboratory have been used in human patients at the University of California, San Francisco, generating never-before-seen recordings of brain activity in the hippocampus, a region responsible for memory and other cognitive functions.
A neurologic pathway by which non-damaging but high frequency brain impact blunts normal brain function and causes long-term problems with learning and memory has been identified. The finding suggests that tailored drug therapy can be designed and developed to reactivate and normalize cognitive function, say neuroscientists at Georgetown University Medical Center.