New research identifies biomarkers that link alcohol use disorder and Alzheimer disease

Researchers agree that alcohol use can produce global and regional tissue volume changes in the brain, and that excessive alcohol use is associated with dementia and cognitive decline. A new study has examined the relationship between Alzheimer disease – the most common type of dementia – and alcohol use disorder (AUD), discovering biomarkers that link the two.

People with Severe Alcohol Use Disorder May Form and Recall Social Memories Differently

People with severe alcohol use disorder tended to have greater difficulty forming new social memories. And, while they had better immediate recall of positive than negative social cues, for longer-term memories, they tended to remember more negative experiences than positive ones.

Alcohol-related blackouts during youth are markers of future neurocognitive risk

Alcohol-related blackouts (ARBs) are fairly common among younger, social drinkers – even considered a rite of passage by some. Yet new research has found that blacking out predicts unique, underlying brain changes involved with learning, memory, and the processing of visual information.

People with Essential Tremor May Have Increased Risk of Dementia

Dementia may be three times more common among people with essential tremor, a movement disorder that causes involuntary shaking, than the general population, according to research released today, March 6, 2024. The study will be presented at the American Academy of Neurology’s 76th Annual Meeting taking place April 13–18, 2024, in person in Denver and online.

Sleep Apnea Symptoms Linked to Memory and Thinking Problems

People who experience sleep apnea may be more likely to also have memory or thinking problems, according to a preliminary study released today, March 3, 2024, that will be presented at the American Academy of Neurology’s 76th Annual Meeting taking place April 13–18, 2024, in person in Denver and online. The study shows a positive association but did not determine whether sleep apnea causes cognitive decline.

Doctor discusses a recent study about dementia.

Tresa Mcneal, MD, at Baylor Scott & White Health, discusses a recent study about dementia. What You Need to Know: Dementia affects thinking, memory and social ability. Stroke can cause dementia. Dementia risks increase for those who are sedentary. Reduce…

Yoga provides unique cognitive benefits to older women at risk of Alzheimer’s disease, study finds

A new UCLA Health study found Kundalini yoga provided several benefits to cognition and memory for older women at risk of developing Alzheimer’s disease including restoring neural pathways, preventing brain matter decline and reversing aging and inflammation-associated biomarkers – improvements not seen in a group who received standard memory training exercises.

Medicine on the base of vitamin B6 improves memory and decreases fatigue after COVID

Scientists have showed that medicine on the base of vitamin B6 can be used for treatment of post-COVID asthenia – condition when patients complain of rapid fatigability, problems with memory and sleep. Taking of this product enabled 35% patients to improve memory, 40% patients began to sleep well, 42% of people began to get tired more slowly. Besides this taking this medicine enabled patients to experience physical activity easier. Results of the research are published in Magazine of Infectology.

Protein p53 regulates learning, memory, sociability in mice

Researchers at the Beckman Institute for Advanced Science and Technology have established the protein p53 as critical for regulating sociability, repetitive behavior, and hippocampus-related learning and memory in mice, illuminating the relationship between the protein-coding gene TP53 and neurodevelopmental and psychiatric disorders.

Concussions Early in Life Tied to Late Life Cognitive Decline

A study of twins shows that having a concussion early in life is tied to having lower scores on tests of thinking and memory skills decades later as well as having more rapid decline in those scores than twins who did not have a concussion, or traumatic brain injury (TBI). The study is published in the September 6, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Penn Medicine Researchers Identify the Link Between Memory and Appetite in the Human Brain to Explain Obesity

Disrupted connections between memory and appetite regulating brain circuits are directly proportional to BMI, notably in patients who suffer from disordered or overeating that can lead to obesity, such as binge eating disorder, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

Addressing disparities in Alzheimer’s disease research

Age-related cognitive decline and the escalating prevalence of Alzheimer’s disease are pressing social challenges as the population of those 65 and older continues to expand. Age is the primary risk factor, but research has shown that social and structural determinants of health play significant roles in the higher incidence of Alzheimer’s among marginalized communities.

Fluctuating Levels of Cholesterol and Triglycerides Linked to Increased Risk of Dementia

Older people who have fluctuating levels of cholesterol and triglycerides may have a higher risk of Alzheimer’s disease and related dementias compared to people who have steady levels, according to new research published in the July 5, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. While the study found a link, it does not prove that fluctuating levels of cholesterol and triglycerides cause dementia.

Taking Good Care of Your Teeth May Be Good for Your Brain

Taking good care of your teeth may be linked to better brain health, according to a study published in the July 5, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study found that gum disease and tooth loss were linked to brain shrinkage in the hippocampus, which plays a role in memory and Alzheimer’s disease. The study does not prove that gum disease or tooth loss causes Alzheimer’s disease; it only shows an association.

Deep-brain stimulation during sleep strengthens memory

This study provides provides the first physiological evidence from inside the human brain supporting the dominant scientific theory on how the brain consolidates memory during sleep. Further, deep-brain stimulation during a critical time in the sleep cycle appeared to improve memory consolidation.

Running Throughout Middle Age Keeps ‘Old’ Adult-born Neurons ‘Wired’

A new study provides novel insight into the benefits of exercise, which should motivate adults to keep moving throughout their lifetime, especially during middle age. Long-term exercise profoundly benefits the aging brain and may prevent aging-related memory function decline by increasing the survival and modifying the network of the adult-born neurons born during early adulthood, and thereby facilitating their participation in cognitive processes.

UC Irvine School of Medicine associate professor awarded 19th Japan Academy Medal

Kei Igarashi, associate professor of anatomy & neurobiology at the University of California, Irvine School of Medicine, has been named one of six scholars to win the 19th Japan Academy Medal. Widely considered the academy’s most prestigious award for Japanese researchers under the age of 45 in all fields of science and humanities, it was bestowed on Igarashi in recognition of his discoveries on the neural circuit mechanisms of associative memory and how they are affected by Alzheimer’s disease.

Events Serve as “Stepping Stones” en Route to Retrieved Memories

Lost your keys again? One way to retrace your steps involves scanning your memory to find them, such as reaching back to the last moment you clearly remember having them—say, as you walked in the door—before skipping ahead to a “phone call” event and then a “watching TV” event, at which point you might recall placing the keys next to the remote.

Multimodal Sequencing Achieves High-Quality Results from Small Volumes of Frozen Tumor Specimens

Columbia researchers invent a multimodal sequencing technique that achieves high-quality results from small volumes of frozen tumor specimens–the ability to study cancer tissues archived in biobanks should increase the number and variety of tumor samples available for scientific analysis and advance the discovery of biomarkers and drug targets.

UCI researchers discover crucial role of brain’s striatum cilia in time perception

Irvine, Calif., Nov. 30, 2022 — Researchers at the University of California, Irvine have discovered that removal of cilia from the brain’s striatum region impaired time perception and judgment, revealing possible new therapeutic targets for mental and neurological conditions including schizophrenia, Parkinson’s and Huntington’s diseases, autism spectrum disorder, and Tourette syndrome.

Controversial Alzheimer’s drug approval sparks surprising impact

Irvine, Calif., Nov. 29, 2022 — When the U.S. Food and Drug Administration gave controversial accelerated approval to the first Alzheimer’s drug in nearly 20 years, it had a surprising impact on attitudes about research into the disease. A survey by University of California, Irvine neuroscientists has found news coverage of the FDA’s decision made the public less willing to volunteer for Alzheimer’s pharmaceutical trials.

Weight Change in Early Parkinson’s May Be Tied to Changes in Thinking Skills

People who gain or lose weight soon after being diagnosed with Parkinson’s disease may be more likely to have changes in their thinking skills than people who maintain their weight, according to a study published in the October 19, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.