Childhood neglect leaves generational imprint
Distinct neural connectivity found in the babies of mothers who experienced neglect as children
Read morePediatrics
Ohio State-led support program suggests a reduction in preterm birth and infant mortality
New research suggests a unique program called Moms2B at The Ohio State University Wexner Medical Center shows a reduction in
Read moreYouths with mood disorders who use marijuana at higher risk of death, self-harm
Not only might youth with mood disorders of greater severity be more inclined to use cannabis than less severely affected youth, but cannabis use can also worsen symptoms and interfere with successful mood disorder treatment
Read moreCHOP Researchers Find NTRK Fusions More Common than Expected in Pediatric Tumors
In a large study of pediatric cancer patients, researchers from Children’s Hospital of Philadelphia (CHOP) have analyzed the frequency, fusion partners, and clinical outcome of neurotrophic tyrosine receptor kinase (NTRK) fusions, which are clinical biomarkers that identify patients suitable for treatment with FDA-approved TRK inhibitors. The researchers found that NTRK fusions are more common in pediatric tumors and also involve a wider range of tumors than adult cancers, information that could help prioritize screening for NTRK fusions in pediatric cancer patients who might benefit from treatment with TRK inhibitors.
Read morePrinciples of care established for young adults with substance use disorders
Supplement published in Pediatrics highlights evidence on how best to address this unique age group
Read moreStudy demonstrates efficacy of new treatment for neurofibromatosis type 1-related tumors
Phase 2 clinical trial involving CHOP and the Neurofibromatosis Clinical Trials Consortium showed cabozantinib reduced tumor volume and pain
Read moreC-Path announces SHIP-MD 2021 Virtual Workshop
Multi-stakeholder event will focus on national innovation ecosystem for pediatric medical device development
Read moreProgression of myopia in children after COVID-19 home confinement
What The Study Did: Researchers investigated the association of home confinement during the COVID-19 outbreak with myopia (nearsightedness) development in
Read moreCHOP and Penn Researchers Identify Nanoparticles that Could Be Used in Therapeutic mRNA Delivery before Birth
Researchers at Children’s Hospital of Philadelphia and the School of Engineering and Applied Science at the University of Pennsylvania have identified ionizable lipid nanoparticles that could be used to deliver mRNA as part of fetal therapy. The proof-of-concept study, published today in Science Advances, engineered and screened a number of lipid nanoparticle formulations for targeting mouse fetal organs and has laid the groundwork for testing potential therapies to treat genetic diseases before birth.
Read moreA new study identifies possible biomarkers of severe malaria in African children
The levels of small molecules called microRNAs (miRNAs) circulating in blood could help identify early on children with life-threatening forms
Read moreResearchers identify nanoparticles that could deliver therapeutic mRNA before birth
Study demonstrates the efficacy and therapeutic potential of select ionizable lipid nanoparticles for delivering mRNA to treat genetic diseases before birth
Read moreStudy: Many summer camps don’t require childhood immunizations
Study suggests that camps, which draw in 14 million children a year, may be an overlooked group when addressing communicable disease spread
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