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AASLD Releases Clinical Insight Guide for Treating Patients with Liver Disease and COVID-19

March 25, 2020 sarah Jonas COVID-19, COVID-19 crisis, COVID-19 epidemiology, COVID-19 research, hepatocellular carcinoma (HCC), Liver Disease, remdesivir, SARS-CoV-2

The American Association for the Study of Liver Disease (AASLD) has released a clinical insight document for clinicians and frontline healthcare providers who are treating patients with liver disease during the COVID-19 pandemic. The document, which cites recent studies conducted in China, assesses how hepatologists and liver transplant physicians/surgeons and their patients may be affected by the COVID-19 virus (also known as SARS-CoV-2) and provides continued guidance on clinical approaches to disease management.

Research Results

New bile discovery will rewrite textbooks

February 26, 2020 sarah Jonas Bile Acid, gastro intestinal cancer, LIVER, Liver Disease, Nature (magazine)

Forget what you know about bile because that’s about to change, thanks to a new discovery made by Michigan State University and published in the current issue of Nature. Much of our knowledge about bile hasn’t changed in many decades. It’s produced in the liver, stored in our gall bladder and injected into our intestine when we eat, where it breaks down fats in our gut.

Research Results

Too Much of a Good Thing May Lead to Too Much of a Liver As Well

February 24, 2020 sarah Jonas Fatty Liver Disease, Hepatology, Liver Disease, Nonalcoholic Steatohepatitis

UC San Diego researchers suggest that prolonged exposure to a pair of antioxidant proteins may contribute to enlargement of the liver and fatty liver diseases.

Research Results

UCLA researchers find new method for measuring treatment of rare liver disease in children

February 19, 2020 sarah Jonas Liver Disease

Study examines the role of small molecule in children with a rare liver disease

Research Results

Study: Two Enzymes Control Liver Damage in NASH

February 6, 2020 sarah Jonas Cancer, Cell Biology, Cirrhosis, Gastrointestinal Cancer, Hepatology, LIVER, Liver Disease, Molecular Biology, Nafld, Nash

After identifying a molecular pathway that allows nonalcoholic steatohepatitis (NASH) to progress into liver cell death, University of California San Diego School of Medicine researchers were able to use these pathways to halt further liver damage.

Research Results

Choosing Common Pain Relievers: It’s Complicated

February 5, 2020 sarah Jonas Arthritis, Cardiovascular Disease, Kidney Disease, Liver Disease, Nsaids, pain, pharmacology, U.S. Food And Drug Administration

About 29 million Americans use over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) to treat pain. Every year in the U.S., NSAID use is attributed to approximately 100,000 hospitalizations and 17,000 deaths. All of these drugs have benefits and risks, but deciding which one to use is complicated for health care providers and their patients. To assist in clinical decision-making, researchers address cardiovascular risks and beyond, which include gastrointestinal and kidney side effects of pain relievers.

Research Results

Liver Fibrosis “Off Switch” Discovered in Mice

January 23, 2020 sarah Jonas 0 Comments Cell Biology, Epigenetics, Gastroenterology, genes, Hepatology, LIVER, Liver Disease, Molecular Biology, Nash

UC San Diego School of Medicine researchers identified several genetic switches, or transcription factors, that determine whether or not liver cells produce collagen — providing a new therapeutic target for liver fibrosis.

Announcement

Two UC San Diego Researchers Elected AAAS Fellows

November 26, 2019 sarah Jonas 0 Comments Awards, Endocrinology, Gastroenterology, Gynecology, Hepatology, Liver Disease, Obstetrics, VIROLOGY

Two researchers at University of California San Diego School of Medicine—Pamela L. Mellon and Aleem Siddiqui—have been named Fellows of the American Association for the Advancement of Science (AAAS), the largest general science organization in the world and publisher of the journal Science.

Announcement

Matthew R. D’Uva to Join AASLD as CEO

November 20, 2019 sarah Jonas 0 Comments Liver Disease

The American Association for the Study of Liver Diseases (AASLD) has appointed Matthew R. D’Uva, FASAE, CAE, as its new chief executive officer, effective January 21, 2020.

Research Results

Innovative Machine Learning Tool Predicts Who Might Have Non-Alcoholic Steatohepatitis

November 8, 2019 sarah Jonas 0 Comments Hepatology, Liver Disease

Data from a new study presented this week at The Liver Meeting® – held by the American Association for the Study of Liver Diseases – found that a machine-learning tool could successfully predict the risk of having non-alcoholic steatohepatitis (NASH) among patients with co-existing diseases.

Research Results

Study Shows Artificial Intelligence Can Detect Language Problems Tied to Liver Failure

November 7, 2019 sarah Jonas 0 Comments Artificial Intelligence, Liver Disease

Natural language processing, the technology that lets computers read, decipher, understand and make sense of human language, is the driving force behind internet search engines, email filters, digital assistants such as Amazon’s Alexa and Apple’s Siri, and language-to-language translation apps. Now, Johns Hopkins Medicine researchers say they have given this technology a new job as a clinical detective, diagnosing the early and subtle signs of language-associated cognitive impairments in patients with failing livers.

Feature

AASLD Foundation Invests $3.42 Million in Liver Disease Research and Career Development

June 25, 2019March 13, 2020 sarah Jonas 0 Comments Budgets and Funding, Liver Disease

Alexandria, VA – The American Association for the Study of Liver Diseases (AASLD) Foundation, the largest private supporter of liver