Curbing depression among caregivers improves control of asthma and lung function in children
Article title: Urinary total conjugated 3-bromotyrosine, asthma severity and exacerbation risk Authors: Zeneng Wang, Weiling Xu, Suzy A. A. Comhair, Xiaoming Fu, Zhili Shao, Rebecca Bearden, Joe G. Zein, Eugene R. Bleecker, Mario Castro, Loren C. Denlinger, John V. Fahy,…
In the study, CHART was applied to data from 2,354 children participating in CHILD, a longitudinal research study launched in 2008 that has been following the physical, social and cognitive development of nearly 3,500 Canadian children from before birth.
From information about the children’s wheezing and coughing episodes, use of asthma medications, and related hospital visits at three years of age, CHART was able to predict with 91% accuracy which of these kids would have persistent wheeze—a key indicator of asthma—by age five.
A groundbreaking research collaborative at Northern Arizona University received another $21 million grant to continue its work to promote health equity and study health disparities among diverse populations of the American Southwest.
It’s best not to combine Halloween scares with allergy and asthma flares. ACAAI has tips for making Halloween safe and fun for kids with allergies and asthma.
U.S. asthma deaths rose by more than 17 percent in 2020 – from 3,524 to 4,145 – marking the first increase in over two decades. Black, Latino, and Native American people continue to face the highest risk of asthma attacks,…
Many therapeutics for asthma and other obstructive lung diseases target the β2-adrenergic receptor (β2AR), a G protein-coupled receptor (GPCR) that rapidly supports airway relaxation when stimulated. Yet, overuse of these agents is associated with adverse health outcomes, including death, which has limited their utility as frontline therapies. Now, a mouse model study published in today’s issue of Molecular Cell, from investigators at University Hospitals (UH) and Case Western Reserve University, identifies a novel strategy to isolate the beneficial effects of β2AR stimulation. This suggests a new therapeutic approach to airway diseases as well as numerous other conditions involving the aberrant function of GPCRs.
Researchers from the Gulf Long-term Follow-up Study (GuLF STUDY) found that workers involved in cleaning up the nation’s largest oil spill were 60% more likely than those who did not work on the cleanup to be diagnosed with asthma or experience asthma symptoms one to three years after the spill.
Scientists have clarified the cellular mechanisms of asthma. The results open new perspectives for effective therapy of the disease.
A team of Rutgers researchers and others inject parasitic worms into mice to study how injured cells trigger an immune response.
Innate lymphoid cells (ILCs) promote lung inflammation in asthma but little is known about how they are suppressed. Researchers at University of California San Diego School of Medicine found RNA-binding protein RBM3 is increased in human and mouse ILCs during…
Early exposure to antibiotics kills healthy bacteria in the digestive tract and can cause asthma and allergies, a new study demonstrates.
Penn State College of Medicine, in partnership with the American Academy of Family Physicians and DARTNet Institute, will receive a nearly $31 million funding award from the Patient-Centered Outcomes Research Institute (PCORI) to conduct a large-scale, comparative study on asthma therapies for patients 12 and older.
Hospital readmissions for asthma are increasing among children, according to a new study, highlighting the gaps in health care for the most common chronic paediatric illness.
Start preparing now to make your 4th of July holiday allergy and asthma-free.
Prescott Woodruff, MD, MPH, a renowned leader in the pathogenesis and treatment of airway disease, has been appointed chief of UC San Francisco’s Division of Pulmonary, Critical Care, Allergy and Sleep Medicine. Prescott will assume the role of chief on July 1.
New research sheds light on underlying epigenetic mechanisms contributing to the development of severe asthma.
Patients with the most severe form of asthma produce special substances in their airways when taking medicine during an asthma attack that block the treatment from working, according to a study where Rutgers scientists collaborated with researchers at Genentech, a member of the Roche Group.
A greater proportion of patients with severe, uncontrolled asthma had more significant clinical responses to tezepelumab than placebo, according to research published at the ATS 2022 international conference. The study showed that nearly half of those enrolled achieved complete response to treatment across measures of exacerbation reduction, asthma control, lung function, and clinician assessment.
A global study of asthma patients by Rutgers and an international team of researchers found a combination of two drugs dramatically reduces the chances of suffering an asthma attack.
Two studies in Annals of Allergy, Asthma and Immunology showed different responses to the stresses of COVID-19. COVID-19 increased anxiety and symptoms for asthma sufferers, while parents of children with food allergies suffered less anxiety.
A drug used to treat asthma and allergies can bind to and block a crucial protein produced by the virus SARS-CoV-2, and reduce viral replication in human immune cells, according to a new study by researchers at the Indian Institute of Science (IISc).
A Rutgers pediatric pulmonologist discusses how to know when asthma becomes life threatening
Rockville, Md. (November 8, 2021)—The activation of muscarinic acetylcholine (M2) receptors could be one of the causes of diseases like asthma and chronic obstructive pulmonary disease (COPD), according to the findings of a new study in the journal Function. The…
A new study being presented at this year’s ACAAI Annual Scientific Meeting followed 5,874 kids with asthma in Los Angeles for 15 years and found no increase in allergic sensitizations.
Asthma and allergies are chronic health conditions that continue to adversely impact the quality of life for many around the world. Thanks to exciting breakthroughs by Mark Siracusa, a researcher at Rutgers, The State University of New Jersey, there may be early signs of light at the end of the tunnel.
This discovery, published in the Proceedings of the National Academy of Sciences (PNAS), suggest that MUC5AC could become a target of better therapeutics to untangle the super thick and sticky mucus that plays a role in health problems for millions of people suffering from pulmonary conditions.
ACAAI is having an in-person meeting this year to deliver the latest news in allergies, asthma, and immunology.
The Red Tide Respiratory Forecast developed by the National Oceanic and Atmospheric Administration’s National Centers for Coastal Ocean Science (NOAA-NCCOS) in partnership with the Gulf of Mexico Coastal Ocean Observing System (GCOOS), the state of Florida and others, is now fully supported and available to the public.
For parents of kids with allergies and asthma, preventing their kids from suffering flares of these conditions, along with preventing COVID-19, will top their priority list this school year.
Irvine, Calif., June 29, 2021 – Fireworks are synonymous in the United States with the celebration of Independence Day and other special events, but the colorful displays have caused a growing risk to public safety in recent years, according to a study by environmental health researchers at the University of California, Irvine.
A new study finds that manipulating the stiffness of the collagen-based support structure of airway cells could lead to a new treatment for asthma. The study is published ahead of print in the Journal of Applied Physiology. It was chosen as an APSselect article for June.
Springtime can be difficult on children who have to deal with allergies on top of their asthma.
Women who were highly exposed to ultra-fine particles in air pollution during their pregnancy were more likely to have children who developed asthma, according to a study published in the American Journal of Respiratory and Critical Care Medicine in May. This is the first time asthma has been linked with prenatal exposure to this type of air pollution, which is named for its tiny size and which is not regulated or routinely monitored in the United States.
Type 2 diabetes patients who also have asthma are benefitting from a diabetes medication, typically given to help the pancreas produce more insulin, that also improves asthma symptoms and may reduce lung and airway inflammation.
Findings are from a systematic review and meta-analysis. Data from 20 randomized controlled trials, which included a total of almost 12,000 patients, were analyzed in the study, providing strong and clear evidence in support of triple-drug therapy.
A national study on childhood asthma led by Henry Ford Health System has found that family history, race and sex are associated in different ways with higher rates of asthma in children.
In a study published in JAMA Pediatrics (hyperlink goes here), researchers found that children with at least one parent with a history of asthma had two to three times higher rates of asthma, mostly through age 4.
This summer, camps for kids will not only have to protect kids from COVID-19, but kids with allergies and asthma will need to be kept safe from an allergic reaction or asthma flare.
Article title: Androgen receptor activation alleviates airway hyperresponsiveness, inflammation and remodeling in a murine model of asthma Authors: Rama Satyanarayana Raju Kalidhindi, Nilesh Sudhakar Ambhore, Premanand Balraj, Taylor Schmidt, M. Nadeem Khan, Venkatachalem Sathish From the authors: “Overall, our findings from…
In advance of a wildfire season projected to be among the worst, the American Thoracic Society has released a report that calls for a unified federal response to wildfires that includes investment in research on smoke exposure and forecasting, health impacts of smoke, evaluation of interventions, and a clear and coordinated communication strategy to protect public health.
Asthma exacerbations rose following a catastrophic Christmas Eve fire that destroyed pollution controls at the Clairton Coke Works – the largest such facility in the nation, a University of Pittsburgh Graduate School of Public Health analysis concludes.
The UChicago Medicine health system provided $567.1 million in community benefits and services to the South Side, and UChicago Medicine Ingalls Memorial provided $89.5 million to Harvey and nearby areas.
The complex patterns of genetic ancestry uncovered from genomic data in health care systems can provide valuable insights into both genetic and environmental factors underlying many common and rare diseases, according to a team of Mount Sinai researchers.
Sarah Komisarow is an Assistant Professor of Public Policy and Economics at the Sanford School of Public Policy at Duke University. She is an applied microeconomist with research interests in public policies that affect children’s health and education. Her work…
New research suggests that the COVID-19 crisis has exacerbated existing racial health care disparities and that during the pandemic, African Americans may have had worse access than whites to outpatient care that could have helped prevent deterioration of their non–COVID-19 health conditions
A new study from Washington University School of Medicine in St. Louis has uncovered a previously unknown role for exosomes in inflammatory respiratory diseases. The study has implications for finding new therapies. Exosomes are tiny compartments released from cells that carry different types of cargo, including inflammatory chemicals called cytokines that can drive lung disease.
Sensor-based inhalers integrated into health care providers’ clinical workflows may help improve medication adherence and support children with asthma – and their families – to more effectively manage this condition, according to a new Northwestern and Lurie Children’s study published in Pediatrics.
Those with asthma are experiencing less asthma control related to an increase in using household disinfectants — known asthma triggers — because of COVID-19, according to a survey co-conducted by University of Illinois Chicago researchers.
Toxicological Sciences continues to feature leading toxicology research in the areas of developmental and reproductive toxicology; endocrine toxicology; neurotoxicology; molecular, biochemical, and systems toxicology; and more.
A new survey in Annals of Allergy, Asthma and Immunology shows that of those who used cannabis, about half smoked it while a third vaped – both “inhalation routes” likely to affect one’s lungs.