A study by researchers at WashU Medicine shows that respiratory viruses can hide out in immune cells in the lungs long after the initial symptoms of an infection have resolved, creating a persistently inflammatory environment that promotes the development of chronic lung diseases such as asthma.
Tag: Asthma
Addressing Health Equity in Childhood Asthma Requires Engaging Affected Communities
Systemic racism remains a significant challenge in efforts to address health disparities in childhood asthma. A new American Thoracic Society report provides practical frameworks to begin the research necessary to make real progress in treating asthma in Black and Latino children, who are more likely than their white counterparts to report to emergency rooms in the U.S.
Cedars-Sinai Experts Available to Comment on Children’s Health Topics
Experts from Cedars-Sinai Guerin Children’s are available to discuss a range of pediatric topics, including infectious diseases, adolescent weight management and the latest pediatric research coming out of the American Academy of Pediatrics (AAP) annual conference happening Sept. 27-Oct. 1 in Orlando, Florida.
Advancing Synthetic Ephedra-Type Alkaloids With a Two-Step Enzymatic Approach
The development of versatile and efficient biocatalysts for the synthesis of α-hydroxyketones and Ephedra-type alkaloids represents a significant advancement in synthetic biology and medicinal chemistry. In this study, researchers explore the potential of acetolactate synthase (AlsS) from Bacillus subtilis (BsAlsS) for the production of phenylacetylcarbinol (PAC) and its derivatives. Additionally, the study investigates the use of intermediate reductive amination enzymes (introduction of amine group using enzymes) for functionalizing α-hydroxyketones to generate synthetic Ephedra-type alkaloids.
Memorial Hermann Invests in Ready, Set, Food as Part of Commitment to Prevent Food Allergies
Memorial Hermann Health System has made an investment in Ready, Set, Food that will further its commitment to educate and equip families with the tools necessary to give their babies the best chance at living a life free of food allergies.
Warehousing Industry Increases Health-Harming Pollutants
First of a kind study shows an average 20% spike of nitrogen dioxide polluting the air for communities located near huge warehouses; people of color harder hit …
Is Your Child With Asthma Ready for Asthma Peak Month in September?
Five tips from the American College of Allergy, Asthma and Immunology to help keep your child’s allergy and asthma symptoms at bay this school year.
Keep Achoos out of Your Red, White and Blue(s) Celebrations
People with allergies and asthma may have a few extra challenges when it comes to 4th of July celebrations. See tips from ACAAI for how to keep asthma and allergy symptoms controlled.
Mount Sinai Experts to Present New Research on Long COVID, Lung Cancer, Asthma, Sleep Apnea, and More at ATS 2024 International Conference
Available for interview on breaking news, trending topics in respiratory medicine
Link between e-cigarette use and early age of asthma onset in U.S. adults found through UTHealth Houston research
A significant link between the use of electronic cigarettes and earlier age of asthma onset in U.S. adults was reported by UTHealth Houston researchers today in the Journal of the American Medical Association (JAMA) Network Open.
IU School of Medicine researchers to present respiratory therapy advancements at ATS 2024
Researchers will showcase promising respiratory disease research at the American Thoracic Society (ATS) 2024 International Conference and ATS 2024 Respiratory Innovation Summit (RIS), May 17-22 in San Diego, California.
Cedars-Sinai Pulmonary and Critical Care Experts Present Latest Research at International Conference
Cedars-Sinai experts in pulmonology, critical care medicine and lung transplant attending the May 17-22 American Thoracic Society’s (ATS) 2024 International Conference in San Diego are available to comment on scientific advances being presented throughout the conference.
Breathing Easier with Asthma — Johns Hopkins Children’s Center Experts Available for Interviews During Asthma Awareness Month
For many children with asthma, May is a peak season — their condition is at its worst, often due to seasonal allergies, pollen or poor air quality that come with this time of year.
Asthma Education is Key to Reducing Deaths Worldwide, Say Respiratory Health Associations
On World Asthma Day 2024 the message is clear: “Asthma Education Empowers.” The Forum of International Respiratory Societies (FIRS), of which the American Thoracic Society is a founding member, stresses the crucial role of education in empowering people with asthma to manage their condition effectively and to know when to seek medical assistance.
Study: Hillocks challenge our understanding of lung biology
A research team from Tufts University School of Medicine and Massachusetts General Hospital is now reporting evidence that hillocks and their stem cells are physiologically distinct from other cells within the lung and consist of a stratified outer layer of scale-like squamous cells that protect an underlying layer of rapidly expanding basal stem cells that are capable of restoring airway tissue after injury.
Contracting RSV Before Age 2 Can Cause Long-term Lung Changes and Impairment
Infants and children who have severe cases of respiratory syncytial virus (RSV) before age 2 are likely to have changes to their lung structure and function that could affect respiratory health later in life.
Are All Types of Asthma the Same? Not by a Long Shot
May is Asthma and Allergy Awareness Month – the ideal time to get the word out on the different types of asthma, as well as the different triggers and treatments.
Researchers Find No Link Between COVID-19 Virus and Development of Asthma in Children
In the wake of the COVID-19 pandemic, many families worried about the long-term effects posed by the SARS-COV-2 virus. Now, researchers found that a SARS-COV-2 infection likely does not increase the risk of asthma development in pediatric patients. The findings were published today in the journal Pediatrics.
You may be breathing in more tiny nanoparticles from your gas stove than from car exhaust
Cooking on your gas stove can emit more nano-sized particles into the air than vehicles that run on gas or diesel, possibly increasing your risk of developing asthma or other respiratory illnesses, a new Purdue University study has found.
New Clinical Practice Guideline Provides Evidence-based Recommendations for Immunotherapy for Inhalant Allergy
The American Academy of Otolaryngology–Head and Neck Surgery Foundation (AAO-HNSF) published the Clinical Practice Guideline: Immunotherapy for Inhalant Allergy today in Otolaryngology–Head and Neck Surgery.
Targeting inflammatory protein could help treat severe asthma
Australian scientists have revealed a promising new treatment for severe asthma, targeting a protein that controls inflammation and scarring of the airways.
Spring Allergies Attack More Than Just Your Nose
Spring allergens such as pollen, mold spores and other airborne particles not only trigger nasal allergies, but also can have a profound effect on a variety of allergic conditions including asthma and eczema
Quality of Care for Patients Who Call 911 Varies Greatly Across the United States, Study Finds
Mount Sinai research could lead to more consistency and safety measure.
Allergy and Asthma Do’s and Don’ts for a Great 2024 Valentine’s Day
Valentine’s Day is around the corner. If the person you love has allergies or asthma, you’ll want to make sure to keep them safe from symptom flares in order to up the “passion quotient.”
Asthma rates climb for high school students as cannabis use increases
Asthma is more common among high school students who use cannabis, relative to those who do not and the prevalence of asthma increases with the frequency of its use among the students, according to a new study at Columbia University Mailman School of Public Health and the City University of New York. The findings are published in the journal Pediatric Pulmonology.
Army of specialized T cells may trigger asthma attacks in older men
LA JOLLA, CA—Scientists from La Jolla Institute for Immunology (LJI) and The University of Southampton, UK, have uncovered a group of immune cells that may drive severe asthma. These cells, called cytotoxic CD4+ tissue-resident memory T cells, gather in the lungs and appear to possess the molecular weaponry to cause the most harm in men who developed asthma later in life.
A Short Chat Goes a Long Way Toward Keeping Halloween Safe for Kids with Allergies and Asthma
At Halloween, if your child has allergies or asthma, they need to be aware of necessary precautions to keep them safe from sudden flares.
Prevent Allergy and Asthma Flares at School: Know Your Child’s Triggers
Allergies and asthma can significantly impact a child’s well-being and academic performance, but with proper preparation and management, they can thrive in the school environment.
CHOP Researchers Validate Pediatric “Allergic March” in Largest National Study of its Kind
In the largest study of its kind, researchers from Children’s Hospital of Philadelphia (CHOP) used electronic health record (EHR) data from more than 200,000 pediatric patients to describe patterns of pediatric allergies across the United States, validating a population-level pattern of allergy development known as the “allergic march,” in which allergies first present as eczema, followed by food allergies, asthma, and environmental allergies. The researchers also found that a rare food allergy called eosinophilic esophagitis (EoE), which has historically been considered a disease affecting primarily White males, is more common among non-White patients than previously reported.
Prevent Red, White and Achoo this Fourth of July
July 4th festivities mean those with allergies and asthma need to take a few extra precautions to make sure their holiday is safe, and sneeze- and wheeze-free.
For Urban Children with Asthma, Where They Live Is Strongest Predictor of Exacerbations
For children with asthma residing in urban areas, the neighborhood they live in is a stronger predictor of whether they will have exacerbations (asthma attacks) than their family’s income or their parents’ level of educational attainment, according to research published at the ATS 2023 International Conference.
Asthma, COPD, Health Disparities Research, and Virtual Press Event: ATS 2023
We’re mere days away from the largest gathering of respiratory health professionals! You can still register to cover ATS 2023 in Washington, DC. Before you join us, here are some of the research abstracts that will be presented to this year’s gathering of pulmonary, critical care and sleep medicine health professionals.
How interleukin-6 helps prevent allergic asthma and atopy by suppressing interleukin-2 signaling
The immune system has a biological telecommunications system — small proteins known as interleukins that send signals among the leukocyte white blood cells to control their defense against infections or nascent cancer.
Childhood Asthma Declines During COVID-19 Pandemic
Half as many children in the United States were diagnosed with asthma in the first year of the COVID-19 pandemic compared to previous years, and Rutgers researchers think fewer colds may be part of the reason.
ATS 2023 Conference Program is Live! Register Now
The ATS 2023 International Conference Program is now live! Get ready for a series of dynamic scientific programming with presentations covering the basic sciences, research breakthroughs and clinical treatment, as well as spotlighting the next generation of innovators.
Summer Camp Goals for Kids with Allergies and Asthma: Stay Safe and Have Fun
Parents of children with allergies and asthma often face an added layer of concern about summer camp as they wonder how they will keep their kids safe from allergy and asthma flares, while allowing them to have great summer fun.
A New Way to Make Asthma Drugs Last Longer
New research into making asthma and COPD medication more potent could also improve how long they work in patients who need frequent doses
LJI researchers find missing piece of the asthma puzzle
“This is a very striking and significant result that essentially separates LIGHT from any of the other inflammatory cytokines that have been implicated in the process in severe asthmatics.”
E-cigarette Use during Pregnancy Creates Lung Dysfunction in Babies
Babies born to mothers who vape during pregnancy are at greater risk of developing pulmonary dysfunction, according to a new mouse study from The Ohio State University.
Treating parents’ depression boosts treatment of children’s asthma, UTSW study finds
Curbing depression among caregivers improves control of asthma and lung function in children
Substance in Urine May Help Determine Asthma Severity
Article title: Urinary total conjugated 3-bromotyrosine, asthma severity and exacerbation risk Authors: Zeneng Wang, Weiling Xu, Suzy A. A. Comhair, Xiaoming Fu, Zhili Shao, Rebecca Bearden, Joe G. Zein, Eugene R. Bleecker, Mario Castro, Loren C. Denlinger, John V. Fahy,…
Simple new tool allows primary caregivers to detect young kids at high risk of asthma
In the study, CHART was applied to data from 2,354 children participating in CHILD, a longitudinal research study launched in 2008 that has been following the physical, social and cognitive development of nearly 3,500 Canadian children from before birth.
From information about the children’s wheezing and coughing episodes, use of asthma medications, and related hospital visits at three years of age, CHART was able to predict with 91% accuracy which of these kids would have persistent wheeze—a key indicator of asthma—by age five.
NAU research collaborative receives $21M grant to continue pioneering work into health equity in the Southwest
A groundbreaking research collaborative at Northern Arizona University received another $21 million grant to continue its work to promote health equity and study health disparities among diverse populations of the American Southwest.
Create Halloween Scares That Are Safe and Fun for Kids with Allergies and Asthma
It’s best not to combine Halloween scares with allergy and asthma flares. ACAAI has tips for making Halloween safe and fun for kids with allergies and asthma.
U.S. asthma deaths increased for first time in two decades with highest risk to Black, Latino and Native American people
U.S. asthma deaths rose by more than 17 percent in 2020 – from 3,524 to 4,145 – marking the first increase in over two decades. Black, Latino, and Native American people continue to face the highest risk of asthma attacks,…
Key Mechanisms of Airway Relaxation in Asthma Revealed in New Study
Many therapeutics for asthma and other obstructive lung diseases target the β2-adrenergic receptor (β2AR), a G protein-coupled receptor (GPCR) that rapidly supports airway relaxation when stimulated. Yet, overuse of these agents is associated with adverse health outcomes, including death, which has limited their utility as frontline therapies. Now, a mouse model study published in today’s issue of Molecular Cell, from investigators at University Hospitals (UH) and Case Western Reserve University, identifies a novel strategy to isolate the beneficial effects of β2AR stimulation. This suggests a new therapeutic approach to airway diseases as well as numerous other conditions involving the aberrant function of GPCRs.
Oil spill cleanup workers more likely to have asthma symptoms
Researchers from the Gulf Long-term Follow-up Study (GuLF STUDY) found that workers involved in cleaning up the nation’s largest oil spill were 60% more likely than those who did not work on the cleanup to be diagnosed with asthma or experience asthma symptoms one to three years after the spill.
Scientists Clarify the Causes of Asthma and Find a Potential Therapy
Scientists have clarified the cellular mechanisms of asthma. The results open new perspectives for effective therapy of the disease.
Newly Discovered “Danger Signal” May Spur Vaccine Development and Allergy Treatment
A team of Rutgers researchers and others inject parasitic worms into mice to study how injured cells trigger an immune response.
RNA-Binding Protein Intrinsically Suppresses Lung Inflammation in Asthma
Innate lymphoid cells (ILCs) promote lung inflammation in asthma but little is known about how they are suppressed. Researchers at University of California San Diego School of Medicine found RNA-binding protein RBM3 is increased in human and mouse ILCs during…