Nanoengineers at the University of California San Diego have developed COVID-19 vaccine candidates that can take the heat. Their key ingredients? Viruses from plants or bacteria.
Scientists at Berkeley Lab and UC Berkeley have developed a nanoparticle composite that grows into 3D crystals. The new 3D-grown material could speed up production and eliminate errors in the mass manufacturing of nanoscale photonics for smart buildings or actuators for robotics.
PNNL’s Dongsheng Li’s crystal formation research helped reveal why nanoparticles sometimes self-assemble into five-sided shapes. The discovery will potentially be useful in medical research, electronics, and other applications.
An international team led by Empa and ETH Zurich researchers is playing with shape-engineered nanoscale building blocks that are up to 100-times larger than atoms and ions. And although these nano “Lego bricks” interact with each other with forces vastly different and much weaker than those holding atoms and ions together, they form crystals all by themselves, the structures of which resemble the ones of natural minerals. These new mega-crystals or superlattices that are depicted on the cover of the latest issue of “Nature” exhibit unique properties such as superfluorescence – and may well usher in a new era in materials science
As antibiotic-resistant bacteria become more prevalent, silver has seen steep growth in its use in things like antibacterial coatings. Still, a better understanding can provide clues on how to best apply it. In Chemical Physics Reviews, researchers monitored the interaction of silver nanoparticles with a nearby E. coli culture and found the silver undergoes several dramatic changes. Most notably, the E. coli cells caused substantial transformations in the size and shape of the silver particles.
The NSF awarded Stefan Wilhelm a $761,727 CAREER award to continue his research in nanotechnology, which assists in the diagnosis and treatment of diseases such as cancer. Wilhelm’s work focuses on individual nanoparticles – which are about 1,000 times smaller than the diameter of a human hair – and how they interact with the body’s cells.
Earth-friendly process may help make critical materials sourcing economically feasible in the U.S.
nanoComposix is proud to announce the successful expansion of its Quality Management System (QMS) to include ISO 13485:2016 certification.
Scientists developed a highly efficient, targeted method for delivering gene editing machinery to specific tissues and organs, demonstrating the treatment of high cholesterol by targeting genes in the liver of mice, reducing cholesterol for over 3 months (and potentially more) with one treatment
ROCKVILLE, MD – Scientists are still a long way from being able to treat Alzheimer’s Disease, in part because the protein aggregates that can become brain plaques, a hallmark of the disease, are hard to study.
Researchers reporting in ACS’ Nano Letters have developed a hydrogel that, when injected into mice with melanoma, slowly released RNA nanovaccines that shrank tumors and kept them from metastasizing.
DALLAS – Feb. 8, 2021 – A new nanoparticle-based drug can boost the body’s innate immune system and make it more effective at fighting off tumors, researchers at UT Southwestern have shown. Their study, published in Nature Biomedical Engineering, is the first to successfully target the immune molecule STING with nanoparticles about one millionth the size of a soccer ball that can switch on/off immune activity in response to their physiological environment.
Nanoengineers at the University of California San Diego have developed new and improved probes, known as positive controls, that could make it easier to validate rapid, point-of-care diagnostic tests for COVID-19 across the globe. The advance could help expand testing to low-resource, underserved areas.
A new platform could accelerate the development of blended materials with desired properties.
A radioisotope researcher in the Radioisotope Science and Technology Division at the Department of Energy’s Oak Ridge National Laboratory, Davern is focusing on ways to use nanoparticles — particles 100 nanometers or smaller that can have special properties — to contain those radioisotopes and deliver them directly to cancer cells, where they can decay into different isotopes that irradiate those cells.
Researchers reporting in ACS’ Nano Letters have developed nanoparticles that release bursts of calcium inside tumor cells, inhibiting drug pumps and reversing MDR.
Engineers have invented a way to spray extremely thin wires made of a plant-based material that could be used in N95 mask filters, devices that harvest energy for electricity, and potentially the creation of human organs. The method involves spraying methylcellulose, a renewable plastic material derived from plant cellulose, on 3D-printed and other objects ranging from electronics to plants, according to a Rutgers-led study in the journal Materials Horizons.
Combining their expertise in protein engineering and synthetic DNA technology, Wistar scientists successfully delivered nanoparticle antitumor vaccines that stimulated robust CD8 T cell immunity and controlled melanoma growth in preclinical models.
A bioengineering technique to boost production of specific proteins could be the basis of an effective vaccine against the novel coronavirus that causes COVID-19, new research suggests.
Researchers report in Science Advances that the lipid-based nanoparticles they have engineered, carrying two sets of protein-making instructions, showed in animal studies that they have the potential to function as therapies for two genetic disorders.
Nanoparticles are actively employed in medicine as contrast agents as well as for diagnosis and therapy of various diseases. However, the development of novel multifunctional nanoagents is impeded by the difficulty of monitoring their blood circulation. Researches from the Moscow Institute of Physics and Technology, the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of RAS, Moscow Engineering Physics Institute, Prokhorov General Physics Institute of RAS, and Sirius University have developed a new noninvasive method of nanoparticle measurement in the bloodstream that boasts a high time resolution. This technique has revealed the basic parameters that affect particle lifetime in the bloodstream, which may potentially lead to discovery of new, more effective nanoagents to be used in biomedicine.
Imagine tiny crystals that “blink” like fireflies and can convert carbon dioxide, a key cause of climate change, into fuels. A Rutgers-led team has created ultra-small titanium dioxide crystals that exhibit unusual “blinking” behavior and may help to produce methane and other fuels, according to a study in the journal Angewandte Chemie. The crystals, also known as nanoparticles, stay charged for a long time and could benefit efforts to develop quantum computers.
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every Tuesday throughout the duration of the outbreak.
Scientists use nanoparticle-delivered gene therapy to limit blinding retinal disease in rodents.
Sauvignon Blanc, Semillon, or Chardonnay – when you reach for your favourite white, it’s the clean, clear sparkle that first catches your eye. Or does it? When white wines look cloudy it’s a sign of protein instability, and a sure-fire way to turn customers away. Now, new research is ensuring white wines will always look their best as novel magnetic nanotechnology is proving to quickly and efficiently remove haze-forming proteins in white wine.
UNIVERSITY PARK, Pa. — The Penn State Center for Structural Oncology (CSO) is shifting some of its focus from fighting cancer to fighting COVID-19, with three projects. The CSO’s director, Deborah Kelly, Lloyd & Dottie Foehr Huck Chair in Molecular Biophysics…
Donghyun Rim, assistant professor of architectural engineering in the Penn State College of Engineering, was recently awarded a $500,000, five-year Early Career Development Program (CAREER) grant from the National Science Foundation (NSF).
Rutgers engineers have created a highly effective way to paint complex 3D-printed objects, such as lightweight frames for aircraft and biomedical stents, that could save manufacturers time and money and provide new opportunities to create “smart skins” for printed parts. The findings are published in the journal ACS Applied Materials & Interfaces.
Researchers at Berkeley Lab have captured 3D images of nanoparticles in liquid with atomic precision, and developed an ultrathin electrical switch that could further miniaturize computing devices and personal electronics without loss of performance.
Researchers in the cancer nanomedicine community debate whether use of tiny structures, called nanoparticles, can best deliver drug therapy to tumors passively — allowing the nanoparticles to diffuse into tumors and become held in place, or actively — adding a targeted anti-cancer molecule to bind to specific cancer cell receptors and, in theory, keep the nanoparticle in the tumor longer. Now, new research on human and mouse tumors in mice by investigators at the Johns Hopkins Kimmel Cancer Center suggests the question is even more complicated.
Nanoparticles have been used to treat disease for decades, but scientists are now learning more about how they move through human tissue. PECASE honoree and NIGMS grantee Elizabeth Nance is enlisting minds across different scientific fields to solve the challenge of using nanoparticles to target the right site within the body to increase the effectiveness of treatments for newborn brain injury.
Researchers have developed a way to prop up a struggling immune system to enable its fight against sepsis, a deadly condition resulting from the body’s extreme reaction to infection.
Scientists have developed a new gene-therapy technique by transforming human cells into mass producers of tiny nano-sized particles full of genetic material that has the potential to reverse disease processes.
Scientists at Johns Hopkins Medicine report they have created a tiny, nanosize container that can slip inside cells and deliver protein-based medicines and gene therapies of any size — even hefty ones attached to the gene-editing tool called CRISPR. If their creation – constructed of a biodegradable polymer — passes more laboratory testing, it could offer a way to efficiently ferry larger medical compounds into specifically selected target cells.
For more than a decade, researchers have used glowing nanoparticles called Cornell dots, or C dots, to illuminate cancer cells, target tumors and even induce cell death.
Rutgers engineers have embedded high performance electrical circuits inside 3D-printed plastics, which could lead to smaller and versatile drones and better-performing small satellites, biomedical implants and smart structures. They used pulses of high-energy light to fuse tiny silver wires, resulting in circuits that conduct 10 times more electricity than the state of the art, according to a study in the journal Additive Manufacturing. By increasing conductivity 10-fold, the engineers can reduce energy use, extend the life of devices and increase their performance.
Researchers from the National University of Singapore have developed a method to give more control to optogenetics, by using specially designed nanoparticles and nanoclusters (dubbed ‘superballs’). These nanoparticles and superballs can emit different colours of light when excited by lasers at different wavelengths. These different colours of light can then be used to trigger specific biological processes.