Nanoparticles enhance gene therapies for eye disease

NIBIB-funded researchers have created nanoparticles for successful gene therapy of a mouse model of macular degeneration. The nanoparticle carriers have the potential to significantly expand the effectiveness of gene therapies for human eye diseases, including blindness.

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Exercise can slow or prevent vision loss, study finds

Exercise can slow or prevent the development of macular degeneration and may benefit other common causes of vision loss, such as glaucoma and diabetic retinopathy, new research suggests.

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Artificial Intelligence Algorithm Can Rapidly Detect Severity of Common Blinding Eye Disease

A new artificial intelligence (AI) algorithm developed by researchers at New York Eye and Ear Infirmary of Mount Sinai (NYEE) can rapidly and accurately detect age-related macular degeneration (AMD), a leading cause of vision loss in the United States.

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Potential Way to Halt Blinding Macular Degeneration Identified

It would be the first treatment for “dry” age-related macular degeneration and could significantly improve treatment for wet AMD.

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Heating Techniques Could Improve Treatment of Macular Degeneration

Age-related macular degeneration is the primary cause of central vision loss and results in the center of the visual field being blurred or fully blacked out. Though treatable, some methods can be ineffective or cause unwanted side effects. Jinglin Huang, a graduate student in medical engineering at Caltech, suggests inefficient fluid mixing of the injected medicine and the gel within the eye may be to blame.

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Better Biosensor Technology Created for Stem Cells

A Rutgers-led team has created better biosensor technology that may help lead to safe stem cell therapies for treating Alzheimer’s and Parkinson’s diseases and other neurological disorders. The technology, which features a unique graphene and gold-based platform and high-tech imaging, monitors the fate of stem cells by detecting genetic material (RNA) involved in turning such cells into brain cells (neurons), according to a study in the journal Nano Letters.

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