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genes

Uncategorized 

CNIO researchers explain the toxicity of USP7 inhibitors, under development for cancer treatment

April 16, 2021 sarah Jonas Biology, BIOMEDICAL/ENVIRONMENTAL/CHEMICAL ENGINEERING, Biotechnology, Cancer, genes, Genetics, MEDICINE/HEALTH, Molecular Biology, TOXICOLOGY

Understanding the components that control cell division is fundamental to understanding how life works and how alterations in this delicate

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CityU biologists discover super-enhancers that switch on breast cancer genes

April 15, 2021 sarah Jonas Bioinformatics, Biology, Biotechnology, Breast Cancer, Cancer, genes, Genetics, MEDICINE/HEALTH, PHARMACEUTICAL SCIENCES, RESEARCH/DEVELOPMENT

Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with a high fatality rate. Currently, chemotherapy is the

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Uncategorized 

Researchers demonstrate very high specificity of prime editors in plants

April 15, 2021 sarah Jonas Biology, genes, Genetics

Prime editing (PE), a “search-and-replace” CRISPR-based genome editing technique, has great potential for gene therapy and agriculture. It can introduce

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Uncategorized 

Japanese-European research team discovers novel genetic mitochondrial disorder

April 15, 2021 sarah Jonas BIOCHEMISTRY, Biology, Cell Biology, DEVELOPMENTAL/REPRODUCTIVE BIOLOGY, genes, Genetics, MEDICINE/HEALTH, Molecular Biology, Neurobiology

Team of Japanese and European scientists identify a novel genetic mitochondrial disorder by analyzing DNA samples from three distinct families

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Uncategorized 

Adam Guenzel, PhD is the recipient of the 2021 Richard King Trainee Award

April 14, 2021 sarah Jonas Diagnostics, genes, Genetics, MEDICINE/HEALTH, METABOLISM/METABOLIC DISEASES

Adam Guenzel, PhD receives the 2021 Richard King Award for Best Publication by a Trainee in Genetics in Medicine

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Uncategorized 

Scientists program microalgae’s ‘oil factory’ to produce various oils

April 14, 2021 sarah Jonas Biology, Cell Biology, genes, Microbiology

By combining the ‘chassis’ of an oil-producing microalgae with genes from a Cuphea plant, scientists from the Single-Cell Center, Qingdao

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Uncategorized 

Simple genetic modification aims to stop mosquitoes spreading malaria

April 13, 2021 sarah Jonas Biology, genes, Genetics, INFECTIOUS/EMERGING DISEASES, MEDICINE/HEALTH

Genetically modifying mosquitoes to express antimalarial genes and pass them on to their offspring is being tested as a new strategy to eliminate malaria

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Uncategorized 

DNA structure itself is involved in genome regulation

April 13, 2021 sarah Jonas BIOCHEMISTRY, Biology, Cancer, Cell Biology, genes, Genetics, Molecular Biology, Public Health

DNA supercoiling is an important contributor to the control of gene expression, and not just collateral damage that cells have to solve

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CNIO scientists discovers a combination therapy for aggressive brain tumors

April 12, 2021 sarah Jonas Biology, Cancer, Cell Biology, Gene Therapy, genes, Genetics, MEDICINE/HEALTH, Molecular Biology, Neurobiology

Glioblastomas are the most common and most aggressive brain tumours. Their survival rate has barely increased over the last 50

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Uncategorized 

For tomato genes, one plus one doesn’t always make two

April 12, 2021 sarah Jonas AGRICULTURAL PRODUCTION/ECONOMICS, Agriculture, Biology, FOOD/FOOD SCIENCE, genes, Genetics, PLANT SCIENCES

Both people and tomatoes come in different shapes and sizes. That is because every individual has a unique set of

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Uncategorized 

How to tame a restless genome

April 8, 2021 sarah Jonas Biology, Cell Biology, genes, Genetics

Short pieces of DNA–jumping genes–can bounce from one place to another in our genomes. When too many DNA fragments move

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Uncategorized 

Reversing a genetic cause of poor stress responses in mice

April 7, 2021 sarah Jonas Biology, genes, Genetics, MEDICINE/HEALTH

Everyone faces stress occasionally, whether in school, at work, or during a global pandemic. However, some cannot cope as well

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Uncategorized 

Carnegie Mellon/Yale PNA-based technique an essential part of the gene editing toolkit

April 7, 2021 sarah Jonas BIOCHEMISTRY, Biology, BIOMEDICAL/ENVIRONMENTAL/CHEMICAL ENGINEERING, Biotechnology, CHEMISTRY/PHYSICS/MATERIALS SCIENCES, Gene Therapy, genes, Genetics, MEDICINE/HEALTH

In an article published in the April 8 issue of Nature , the National Institutes of Health’s Somatic Cell Gene

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Uncategorized 

An international study reveals how the ‘guardian’ of the genome works

April 6, 2021 sarah Jonas Biology, BIOMECHANICS/BIOPHYSICS, BIOMEDICAL/ENVIRONMENTAL/CHEMICAL ENGINEERING, Biotechnology, Cancer, Cell Biology, genes, Genetics, MEDICINE/HEALTH, Molecular Biology

The study is published in ‘Nature Structural & Molecular Biology’

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Uncategorized 

New perspective to understand and treat a rare calcification disease

April 6, 2021 sarah Jonas Biology, genes, Genetics, METABOLISM/METABOLIC DISEASES

Researchers developed a new animal model to study a rare genetic disease that can lead to blindness at the age of 40-50.

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Research Results 

Thirteen new Alzheimer’s genes identified in first-of-its-kind human genome study

April 2, 2021 sarah Jonas Alzheimer's Disease, genes, Neurobiology

In the first study to use whole genome sequencing (WGS) to discover rare genomic variants associated with Alzheimer’s disease (AD), researchers have identified 13 such variants (or mutations).

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Uncategorized 

Scientists launch ‘herculean’ project creating atlas of human genome variants

April 1, 2021 sarah Jonas Bioinformatics, Biology, Biotechnology, Cell Biology, genes

SEATTLE (April 1, 2021) – An international consortium of geneticists, biologists, clinicians, mathematicians, and other scientists is determined to take

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Uncategorized 

Bringing gene editing into high schools

April 1, 2021 sarah Jonas BIOCHEMISTRY, Biotechnology, Education, Gene Therapy, genes, Genetics, K-12, Molecular Biology

Toolkit easily incorporates into any laboratory science course

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Uncategorized 

$1.7 million grant to unlock barley’s genetic superpowers

March 30, 2021 sarah Jonas AGRICULTURAL PRODUCTION/ECONOMICS, Agriculture, BIOCHEMISTRY, Climate Change, Evolution, FOOD/FOOD SCIENCE, genes, Genetics, PLANT SCIENCES

Project to groom undergrads for agricultural science careers

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Uncategorized 

Prime editing enables precise gene editing without collateral damage

March 30, 2021 sarah Jonas Biotechnology, Gene Therapy, genes, MEDICINE/HEALTH

The latest gene editing technology, prime editing, expands the “genetic toolbox” for more precisely creating disease models and correcting genetic

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Uncategorized 

UC consortium launches first clinical trial using CRISPR to correct sickle cell gene

March 30, 2021 sarah Jonas genes, Genetics, MEDICINE/HEALTH, pain, Pediatrics, Public Health, SOCIAL/BEHAVIORAL SCIENCE

Project uses Nobel-Prize-winning technology to directly correct sickle mutation in blood stem cells, addressing underlying cause of debilitating disorder

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Uncategorized 

Everyone poops: Monitoring COVID-19 in wastewater

March 30, 2021 sarah Jonas Bioinformatics, Biology, Biotechnology, genes, Genetics, INFECTIOUS/EMERGING DISEASES, Molecular Biology, Public Health, VIROLOGY

University of Missouri scientists receive $4 million grant from the National Institutes of Health to examine clues about the rate of infection in communities and virus variants

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Uncategorized 

UMD reports six novel variants for CRISPR-Cas12a in plants, expanding genome engineering

March 29, 2021 sarah Jonas Agriculture, BIOMEDICAL/ENVIRONMENTAL/CHEMICAL ENGINEERING, FOOD/FOOD SCIENCE, genes, Genetics, PLANT SCIENCES

New publication in Nature Communications offers patentable tools to improve the efficiency of food production

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Uncategorized 

Genetic sleuthing reveals endangered river dolphins in Asia as different species

March 29, 2021 sarah Jonas Biology, ECOLOGY/ENVIRONMENT, FISHERIES/AQUACULTURE, genes, Genetics, MARINE/FRESHWATER BIOLOGY, POPULATION BIOLOGY

Tissue collection at NOAA Fisheries lab helps reveal genetic distinction

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Uncategorized 

Inflammation-fighting protein could improve treatment of rheumatoid arthritis

March 29, 2021 sarah Jonas Cell Biology, genes, IMMUNOLOGY/ALLERGIES/ASTHMA, MEDICINE/HEALTH, Molecular Biology, PHARMACEUTICAL SCIENCES

SPOKANE, Wash. – New research led by scientists at Washington State University has found that a protein known as GBP5

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Uncategorized 

Study shows survival mechanism for cells under stress

March 29, 2021 sarah Jonas Alzheimer's Disease, Biology, Biotechnology, Cancer, Cell Biology, genes, MEDICINE/HEALTH, Neurobiology

New research reveals how cancer cells endure stress and survive. Publishing in Molecular Cell , an international research team identified

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Uncategorized 

John D. Carpten elected fellow of AACR Academy

March 29, 2021 sarah Jonas BIOCHEMISTRY, Biology, Breast Cancer, Cancer, Gene Therapy, genes, Genetics, prostate cancer, RESEARCH/DEVELOPMENT, RESEARCHERS/SCIENTISTS/AWARDS

American Association for Cancer Research honors distinguished USC Norris Comprehensive Cancer Center scientist

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Uncategorized 

A mouse’s bite holds venomous potential, finds new study

March 29, 2021 sarah Jonas Biology, Evolution, genes, Genetics

Startling new evidence shows mammal salivary glands and snake venom glands share a common genetic foundation.

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Research Results 

Dogs (not) gone wild: DNA tests show most ‘wild dogs’ in Australia are pure dingoes

March 26, 2021 sarah Jonas genes, Genetics

Almost all wild canines in Australia are genetically more than half dingo, a new study led by UNSW Sydney shows – suggesting that lethal measures to control ‘wild dog’ populations are primarily targeting dingoes.

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Uncategorized 

Correcting altered brain circuit could tackle coinciding obesity and depression

March 26, 2021 sarah Jonas Biology, DEPRESSION/ANGER, DIET/BODY WEIGHT, EATING DISORDERS/OBESITY, genes, Genetics, MEDICINE/HEALTH, Mental Health, PHARMACEUTICAL SCIENCES

Research has found that obesity and mental disorders such as depression and anxiety seem to often go hand in hand.

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Uncategorized 

Gray’s beaked whales ‘resilient’ to ecosystem changes

March 26, 2021 sarah Jonas Biodiversity, Biology, Climate Change, ECOLOGY/ENVIRONMENT, Evolution, genes, Genetics, MARINE/FRESHWATER BIOLOGY, POPULATION BIOLOGY, ZOOLOGY/VETERINARY SCIENCE

An elusive whale species in the Southern Ocean could be resilient to near-future ecosystem changes, according to a new study

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Uncategorized 

Dogs (not) gone wild: DNA tests show most ‘wild dogs’ in Australia are pure dingoes

March 26, 2021 sarah Jonas Agriculture, ANIMAL RESEARCH/RIGHTS, Biodiversity, Biology, genes, Genetics

It’s time to take dingoes out of the doghouse

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Uncategorized 

Researchers discover why cold induces tooth pain and hypersensitivity — and how to stop it

March 26, 2021 sarah Jonas Cell Biology, DENTISTRY/PERIODONTAL DISEASE, genes, MEDICINE/HEALTH, pain

Odontoblasts, the cells that form a tooth’s dentin, have a newly discovered function: Sensing cold, which can trigger pain in teeth; but scientists have also found a way to block the pathway to cold-sensitive teeth

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Uncategorized 

Ancient genomes trace the origin and decline of the Scythians

March 26, 2021 sarah Jonas Anthropology, Archaeology, genes, Genetics, History, IMMIGRANTS & MIGRATION, OLD WORLD

Because of their interactions and conflicts with the major contemporaneous civilizations of Eurasia, the Scythians enjoy a legendary status in

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Uncategorized 

Circadian clock gene Rev-erb linked to dawn phenomenon in type 2 diabetes

March 25, 2021 sarah Jonas Biology, genes, Genetics, LIVER, MEDICINE/HEALTH, METABOLISM/METABOLIC DISEASES, Physiology, Type 2 Diabetes

Researchers at Baylor College of Medicine, Shandong University in China and other institutions may have found an explanation for dawn

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Uncategorized 

Researchers improve plant prime editing efficiency with optimized pegRNA designs

March 25, 2021 sarah Jonas Biology, Gene Therapy, genes, Genetics, PLANT SCIENCES

Precision genome editing enables the precise modification of DNA in living cells, thus enabling a breadth of opportunities for plant

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Uncategorized 

Plant gene found in insect, shields it from leaf toxins

March 25, 2021 sarah Jonas Agriculture, Biology, ECOLOGY/ENVIRONMENT, Entomology, Evolution, FERTILIZERS/PEST MANAGEMENT, genes, Genetics, Molecular Biology

Millions of years ago, aphid-like insects called whiteflies incorporated a portion of DNA from plants into their genome. A Chinese

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Uncategorized 

Study links genes with function across the human brain

March 25, 2021 sarah Jonas BEHAVIOR, genes, Genetics, MEDICINE/HEALTH, MEMORY/COGNITIVE PROCESSES, Mental Health, Neurobiology, PERSONALITY/ATTITUDE

Comparing two neural maps reveals the roles of genes in cognition, perception and feeling

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Uncategorized 

Gene required for jumping identified in rabbits

March 25, 2021 sarah Jonas Biology, genes, Genetics, PETS/ETHOLOGY, ZOOLOGY/VETERINARY SCIENCE

Experiments with a rare type of rabbit that can’t jump pinpointed the necessary gene

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Uncategorized 

Genome sequenced for pesky pumpkin pathogen

March 24, 2021 sarah Jonas AGRICULTURAL PRODUCTION/ECONOMICS, Agriculture, BACTERIOLOGY, Biology, FERTILIZERS/PEST MANAGEMENT, genes, Genetics, Microbiology, PLANT SCIENCES

URBANA, Ill. – Pumpkin growers dread the tiny tan scabs that form on their fruit, each lesion a telltale sign

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Uncategorized 

Scientists discover how humans develop larger brains than other apes

March 24, 2021 sarah Jonas BIOCHEMISTRY, Biology, Cell Biology, DEVELOPMENTAL/REPRODUCTIVE BIOLOGY, Evolution, genes, MEDICINE/HEALTH, Neurobiology

A new study is the first to identify how human brains grow much larger, with three times as many neurons,

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Uncategorized 

How human cells coordinate the start of DNA replication

March 23, 2021 sarah Jonas Biology, genes, Genetics

Cold Spring Harbor Laboratory (CSHL) President and CEO Bruce Stillman has been dissecting DNA replication, a critical step in cell

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Uncategorized 

Large-scale genome analysis identifies differences by sex in major psychiatric disorders

March 23, 2021 sarah Jonas genes, Genetics, MEDICINE/HEALTH, Mental Health, Neurobiology

Investigators in a multinational study scanned genomes of nearly 200,000 people to find interactions with genes and sex for schizophrenia, major depressive disorder and bipolar disorder.

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Uncategorized 

Massey researcher finds new strategy for fighting brain cancer

March 23, 2021 sarah Jonas Biology, Cancer, Cell Biology, genes, MEDICINE/HEALTH

Most people relate cholesterol to heart health, but it is also a critical component in the growth and spread of

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Uncategorized 

Rare genetic variant puts some younger men at risk of severe COVID-19

March 23, 2021 sarah Jonas Biology, genes, Genetics, INFECTIOUS/EMERGING DISEASES, MEDICINE/HEALTH

A subset of young men carry a genetic variant that dampens innate immunity to COVID-19 and may benefit from genetic testing and interferon treatment

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Uncategorized 

Researchers hunt for drugs that keep HIV latent

March 23, 2021 sarah Jonas AIDS/HIV, Biology, Cell Biology, genes, Genetics, INFECTIOUS/EMERGING DISEASES, MEDICINE/HEALTH, Microbiology

When the human immunodeficiency virus infects cells, it can either exploit the cells to start making more copies of itself

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Uncategorized 

Direct reprogramming of oral epithelial cells into mesenchymal-like cells

March 22, 2021 sarah Jonas Biology, Cell Biology, DENTISTRY/PERIODONTAL DISEASE, genes

Point Epithelial cell rests of Malassez derived from the periodontal ligament were transformed into progenitor stem-like cells by stimulation with

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Uncategorized 

Upgrade for CRISPR/Cas: Researchers knock out multiple genes in plants at once

March 22, 2021 sarah Jonas BIOCHEMISTRY, Biology, BIOMEDICAL/ENVIRONMENTAL/CHEMICAL ENGINEERING, Biotechnology, CHEMISTRY/PHYSICS/MATERIALS SCIENCES, genes, Genetics, PLANT SCIENCES

Using an improved version of the gene editing tool CRISPR/Cas9, researchers knocked out up to twelve genes in plants in

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Uncategorized 

Cholesterol accumulation contributes to genetic movement disorder

March 22, 2021 sarah Jonas Biology, DEVELOPMENTAL/REPRODUCTIVE BIOLOGY, Diagnostics, genes, Genetics, MEDICINE/HEALTH, Molecular Biology, Parkinson's Disease

Family finds hope in research breakthrough for rare diagnosis

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Uncategorized 

Budget impact of gene therapy for sickle cell disease

March 22, 2021 sarah Jonas Cell Biology, DEVELOPING COUNTRIES, genes, HEALTH CARE SYSTEMS/SERVICES, Insurance, MEDICINE/HEALTH, SOCIOECONOMICS

What The Study Did: This economic evaluation estimates the budget impact and affordability of a gene therapy for severe sickle

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