Physicians prescribed opioids more often to their white patients who complained of new-onset low back pain than to their Black, Asian and Hispanic patients during the early days of the national opioid crisis, when prescriptions for these powerful painkillers were surging but their dangers were not fully apparent.
Researchers identified 579 locations in the human genome associated with a predisposition to self-regulation-related behaviors, such as addiction. With data from 1.5 million people of European descent, the effort is one of the largest genome-wide association studies to date.
Five years ago, CDC released an evidence-based guideline to help doctors treat their patients’ pain while balancing the risks and benefits of prescription opioid medications. A new study suggests it may have started to have an effect in the first two years after its launch.
A UC Davis Health study published in JAMA found a 68% increase in overdose events and a doubling of mental health crises among patients who were on stable opioid therapy but saw their doses tapered.
The National Institutes of Health (NIH) is embarking on a massive research project to shed light on early child development, including the health and developmental implications of opioid use during pregnancy. The very first task is to ensure the study — the HEALthy Brain and Child Development study (HBCD) — is on solid legal and ethical ground.
Emergency department visit rates because of an opioid overdose increased by 28.5% across the U.S. in 2020, compared to 2018 and 2019, recent Mayo Clinic research finds. Emergency visits overall decreased by 14% last year, while visits because of an opioid overdose increased by 10.5%. The result: Opioid overdoses were responsible for 0.32 out of 100 visits, or 1 in every 313 visits, which is up from 0.25, or 1 in every 400 visits, the previous two years.
Members of a coalition of 50+ leading public health groups who issued a set of five guiding principles for spending opioid settlement funds in January are reacting to the announcement of the $26 billion settlement deal between a group of state attorneys general and Cardinal Health, AmerisourceBergen, McKesson, and Johnson & Johnson.
Surgeons can ease their patients’ pain from common operations without prescribing opioids, and avoid the possibility of starting someone on a path to long-term use, a pair of new studies suggests.
A pain-management protocol designed by Emese Zsiros, MD, PhD, FACOG, to be reported at the American Society of Clinical Oncology 2021 annual meeting, resulted in a 45% decrease in opioids prescribed to patients undergoing surgery, without significant effect on recovery or satisfaction.
At the American Society of Clinical Oncology 2021 virtual Annual Meeting, Roswell Park teams will share data and insights on topics ranging from reducing use of opioids to an analysis of trends in response to cancer treatment among patients of different races.
o help increase access to the availability of non-opioid pain management treatments, the American Association of Nurse Anesthetists (AANA) supports the recent introduction of the Non-Opioids Prevent Addiction in the Nation (NOPAIN) Act introduced by U.S. Rep. Terri Sewell (D-AL), along with Reps. David McKinley (R-WV), Ann Kuster (D-NH), and Brian Fitzpatrick (R-PA). The Senate version of this legislation (S. 589) was previously introduced.
Researchers at University of California San Diego School of Medicine found that functional impairments among adults aged 50 and older are associated with a higher risk of medical cannabis use; and prescription opioid and tranquilizer/sedative use and misuse.
Amid the rising toll of opioid overdoses and deaths in the U.S., several states are considering laws enabling civil commitment for involuntary treatment of patients with substance use disorders (SUDs). Most addiction medicine physicians support civil commitment for SUD treatment – but others strongly oppose this approach, reports a survey study in Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine (ASAM). The journal is published in the Lippincott portfolio by Wolters Kluwer.
Programs that provide ongoing support to patients with painful conditions and complex medication regimens may also help them avoid using potentially risky opioid pain medications, or reduce the amount they use, a new study finds.
Researchers find that opioids are not necessary for managing post-knee surgery pain.
UC San Diego School of Medicine researchers report that opioid users who participated in a 12-step abstinence program and recently stopped using drugs refused to take home naloxone, even if having it on hand might save lives.
A Penn Medicine new study of how text messaging could inform opioid prescribing practices showed that 60 percent of opioids are left over after orthopaedic and urologic procedures
The Arkansas Society of Anesthesiologists (ARSA) and the American Society of Anesthesiologists (ASA) today applaud bill sponsor Sen. Cecile Bledsoe and the Arkansas Senate Public Health, Labor and Welfare Committee for helping to ensure the safety of patients prescribed opioids. Arkansas State Drug Director Kirk Lane and Jonathan Goree, M.D., a physician anesthesiologist and pain medicine specialist, testified for the bill.
Researchers at Penn Medicine used machine learning-aided analysis to uncover top positive and negative themes in patient Yelp reviews of substance use treatment facilities
Although the prevalence of opioid use among Black people is comparatively low, the rate of opioid deaths has increased the sharpest and fastest among that population in recent years, according to an article in the March/April issue of Harvard Review of Psychiatry. The journal is published in the Lippincott portfolio by Wolters Kluwer.
People over 65 shouldn’t take three or more medicines that act on their brain and nervous system, experts strongly warn, because the drugs can interact and raise the risk of everything from falls to overdoses to memory issues.
But a new study finds that 1 in 7 people with dementia who live outside nursing homes are taking at least three of these drugs.
Despite a Mexican government initiative launched in 2015 to improve access to prescription opioids among palliative care patients, the country has seen only a marginal increase in dispensing levels, and inequities in dispensing have left many of the nation’s poorest residents without comfort in their final days
People treated with chronic opioid therapy for pain are more likely to live in socially disadvantaged areas and self-report worse anxiety, depression and pain that interferes in their lives, according to a new study presented this week at the Association of Academic Physiatrists Annual Meeting.
As surgeons balance the need to control their patients’ post-surgery pain with the risk that a routine operation could become the gateway to long-term opioid use or addiction, a new study shows the power of an approach that takes a middle way.
People who take opioid medications for chronic pain may have a hard time finding a new primary care clinic that will take them on as a patient if they need one, according to a new “secret shopper” study of hundreds of clinics across the country.
A coalition of 31 professional and advocacy organizations has released a set of principles aimed at guiding state and local spending of the forthcoming opioid litigation settlement funds.
New research into opioid overdoses that occurred during the COVID-19 pandemic highlighted new disparities along racial lines that are likely fueled by existing inequality
A new report from researchers at the Johns Hopkins Bloomberg School of Public Health offers recommendations aimed at federal, state, and local policymakers to address the opioid epidemic during the pandemic.
Dr. Lorraine Kelley-Quon forms team of health care providers and community advocates to establish recommendations for safe opioid use. According to the National Institutes of Health, opioid misuse and addiction in the United States is a national crisis, with an economic burden upwards of $78 billion. Opioids are useful for pain management following surgery and other major procedures, but until now there have been no recommendations guiding safe use of opioids in children.
A wave of new studies shows what happens when surgical teams work together to reduce the emphasis on, and supply of, opioid painkillers while still seeking to ease surgery patients’ pain.
In a study of cancer patients treated with methylnaltrexone, about 50%–70% experienced relief from opioid-induced constipation within 4 hours without the use of additional treatments, compared with 15% of placebo-treated patients. In addition, more patients treated with methylnaltrexone maintained a response at 24 hours after dosing compared with patients treated with placebo.
An epidemic that was already raging before COVID-19 arrived has flared up in recent months, according to a real-time tracking system in Michigan. It shows a 15 percent rise in suspected opioid overdose deaths since March, compared with the same time last year, and a 29% rise in first responders’ use of the rescue drug naloxone.
Multiple centers will study acupuncture for pain in the emergency department setting.
A new study suggests that patients with opioid use disorder may be identified using information available in electronic health records, even when diagnostic codes do not reflect this diagnosis. The study demonstrates the utility of proxies coding for DSM-5 criteria from medical records to generate a quantitative DSM-5 score that is associated with opioid use disorder severity. The study methods are unique in deriving a severity score that aims to mirror severity scores from more traditional interview-based diagnostic procedures.
New research presented at the virtual American College of Surgeons Clinical Congress 2020 reports that opioid guidelines may be missing a small group of patients that need a greater level of pain control.
A new study by researchers at the University of Illinois Chicago and the University of Pittsburgh suggests that a significant proportion of older patients receiving opioids at dental visits also use psychotropic medications — a potentially harmful combination. Their findings are published in the journal Pharmacotherapy.
The first-ever virtual American College of Surgeons (ACS) Clinical Congress 2020 will convene October 3-7, offering surgeons and guest clinicians both live and on-demand sessions.
Mizuho OSI®, a leading manufacturer of specialty surgical tables and pressure injury abatement solutions would like to announce the publication of a new clinical study titled “23-hour Total Hip Replacement Requiring Only 3.5 Opioid Pills Through 6 Weeks: A Non-selected Prospective Consecutive One Year Cohort”, by Andrew Wickline MD, now appearing in the peer-reviewed Journal of Orthopedic Experience & Innovation (JournalOEI)
In May, ambulance data recorded a 42 percent increase in overdose-related calls, nationwide In 2019, nearly 72,000 Americans died from drug overdoses, with many involving opioids. With the emergence of the SARS-CoV-2 pandemic, many experts — including those at UC…
A study showed that patients receiving messages from a chatbot used a third fewer opioids after fracture surgery, and their overall pain level fell, too
University of Wisconsin–Madison scientists have discovered that a majority of back-pain patients they tested who were taking opioid painkillers produced anti-opioid antibodies. These antibodies may contribute to some of the negative side effects of long-term opioid use.
Opioid users can develop chronic inflammation and heightened pain sensitivity. These side effects might stem from the body’s own immune system, which can make antibodies against the drugs. The researchers will present their results at the American Chemical Society Fall 2020 Virtual Meeting & Expo.
A Keck Medicine of USC study reveals that kappa opioids, a significantly less addictive opioid, may preserve cartilage in joints and ease pain
A Henry Ford Hospital study published in the Journal of Arthroscopic and Related Surgery has found that patients who underwent knee surgery and other types of sports medicine procedures could manage their pain without opioids or a minimal dosage. “This is a large prospective study and our hope is that non-opioid use will gain momentum and that others may tweak our protocol and use it throughout orthopedics, from joint surgery to spine surgery and other surgeries” says Vasilios (Bill) Moutzouros, M.D., chief of Sports Medicine, a division of the Department of Orthopedic Surgery and the study’s lead author.
Nearly 10 percent of patients who are prescribed opioid medications following heart surgery will continue to use opioids more than 90 days after the procedure, according to a new study led by researchers in the Perelman School of Medicine at the University of Pennsylvania.
Delta opioid receptors have a built-in mechanism for pain relief and can be precisely targeted with drug-delivering nanoparticles—making them a promising target for treating chronic inflammatory pain with fewer side effects, according to a new study from an international team of researchers. The study, published in Proceedings of the National Academy of Sciences (PNAS), was conducted using cells from humans and mice with inflammatory bowel disease, which can cause chronic pain.
Middle-aged and older adults who identify as lesbian, gay, or bisexual have higher rates of using certain substances in the past year than those who identify as heterosexual, according to a new study led by researchers at NYU Grossman School of Medicine and the Center for Drug Use and HIV/HCV Research (CDUHR) at NYU School of Global Public Health.
As dentists and their teams across America get back to their regular schedules after a sharp COVID-19-related reduction, a new study shows a key opportunity to reduce the use of opioid painkillers by their patients.
The analysis shows that those who had dental procedures on a Friday or a day before a holiday were much more likely to fill a prescription for an opioid than other patients.
When Kentucky Gov. Andy Beshear announced the early release of some Kentucky inmates due to COVID-19 concerns, the team behind the HEALing Communities Study worked quickly to fast-track one of the evidence-based practices for preventing opioid deaths that was due to launch later this year: the distribution of naloxone to individuals at highest risk for overdose, particularly those being released from local jails.
Offering $750 to emergency medicine physicians exponentially increased those trained to prescribe buprenorphine.