Widespread skin diseases such as psoriasis or neurodermatitis are difficult to treat. Together with an industrial partner, Empa researchers have found an innovative solution: Nanoceramic “stars” create tiny skin lesions and allow therapeutic molecules to reach their site of action.
Tag: Psoriasis
Stop itchy skin in its tracks
Itchy skin can be irritating, especially an itch that doesn’t go away. There are many potential causes for itchy skin like common skin conditions such as eczema, shingles, hives, psoriasis, or bug bites, or it could be a sign of a contagious disease, like scabies or ringworm. While these causes could mean a visit to a board-certified dermatologist, there are options for self-care at home to provide itch relief.
High Levels of a Specific Antibody May Contribute to Acute Coronary Syndrome
How a person’s immune system responds to a protein called LL-37 may increase risk for developing acute coronary syndrome, but the response may also serve as a potential target for future treatments.
Genetics, Sex and Smoking Linked to More Health Issues for IBD Patients
Investigators at Cedars-Sinai have identified risk factors that make inflammatory bowel disease (IBD) patients susceptible to developing serious conditions in other parts of their bodies.
NUTRITION 2023 Press Materials Available Now
Press materials are now available for NUTRITION 2023, the annual flagship meeting of the American Society for Nutrition (ASN).
How to relieve itchy psoriasis
Skin issues can have a serious impact on your health and well-being. For the 7.5 million Americans1 living with psoriasis, itch can be the most bothersome part of their condition because it can make it difficult to sleep and hard to concentrate, as well as affect other aspects of their quality of life.
Treatment Options for Pregnant Women Living with Eczema and Psoriasis
Psoriasis and eczema affect men and women differently, with women needing to take extra precautions when considering treatments if they’re planning for pregnancy.
Uncovering the skin’s secrets: Studies show how skin forms differently across the body
Two recent UC Davis studies reveal how skin forms differently across different areas of the body from the face and underarms to the palms of our hands and feet. By profiling the changes in skin, researchers found that the differences have a direct impact for how various skin diseases form across the body.
Penn Research Finds Psoriasis Medication Apremilast Leads to Fat Loss in People with Psoriasis
Apremilast (brand name Otezla) has helped psoriasis patients achieve clearer skin and ease the symptoms of their psoriatic arthritis. Now, new data from researchers at the Perelman School of Medicine at the University of Pennsylvania shows it could also help people with psoriasis shed unhealthy body fat and therefore improve cardiovascular health, a well-known vulnerability for those with psoriasis.
Suffering from psoriasis? Blame this trio of proteins
About 7.5 million Americans suffer from psoriasis, an autoimmune disease that shows up as patches of red, inflamed skin and painful, scaly rashes. Although there are effective treatments for psoriasis, not everyone responds to these therapies—and for many, the relief is temporary.
An Inflammation to Remember
A new discovery of a physiological mechanism of psychosomatic illnesses could open a new therapeutic avenue for treating chronic inflammatory conditions such as Crohn’s disease, psoriasis, and other autoimmune conditions, by attenuating their memory trace in the brain.
For psoriasis, molecular signature in healthy-appearing skin may be best predictor of response to anti-TNF treatment
It’s common for people with psoriasis to develop dry, inflamed skin lesions. But researchers found specific gene expression changes in healthy-appearing skin were a better predictor of clinical response to etanercept, an anti-TNF treatment prescribed to up to one-fifth of psoriasis patients. They say finding predictive signs in a patient’s genetic profile is a step toward applying precision medicine to complex inflammatory skin diseases.
For psoriasis, targeting skin protein may help control inflammation
Targeting a protein found in the skin may reduce the severity of psoriasis, a Michigan Medicine study found. Using a mouse model to mimic psoriasis, researchers found changing levels of interferon kappa altered the severity of inflammation.
Engineers build nanostructures that fight inflammation
Nanofiber-based treatments stimulate the body to mount its own biological attack on immune disorders.
Switching from Western diet to a balanced diet may reduce skin, joint inflammation
Diet rich in sugar and fat leads to disruption in the gut’s microbial culture and contributes to inflammatory skin diseases such as psoriasis. Research shows that switching to a more balanced diet restores the gut’s health and suppresses inflammation.
Researchers discover potential new approach to treating psoriatic joint inflammation
An international team of researchers, led by UC Davis Health, developed a new therapeutic approach to treating psoriatic arthritis, a chronic inflammatory disease affecting the joints.
Study Reveals Details of Immune Defense Guidance System
At the beginning of an immune response, a molecule known to mobilize immune cells into the bloodstream, where they home in on infection sites, rapidly shifts position, a new study shows. Researchers say this indirectly amplifies the attack on foreign microbes or the body’s own tissues.
Low fitness linked to higher psoriasis risk later in life
In a major register-based study, scientists at University of Gothenburg, Sweden, have now demonstrated a connection between inferior physical fitness in young adults and elevated risk of the autoimmune disease psoriasis.
IPC Statement On SARS-CoV-2 Vaccines And Psoriasis
The SARS-CoV-2 pandemic continues to have a considerable impact on the provision of appropriate care to people with psoriasis.
Mount Sinai Researcher Identifies Single Gene Biomarker to Differentiate Between Atopic Dermatitis and Psoriasis Using Adhesive Tape Strips
Mount Sinai researchers have pinpointed a single gene biomarker, nitride oxide synthase 2 (NOS2) that can distinguish atopic dermatitis (AD) and psoriasis with 100 percent accuracy using adhesive tape strips, a non-invasive alternative to skin biopsy. The research will be published online today in the Journal of Allergy and Clinical Immunology.
Mount Sinai Researchers Discover That Topical Treatment Improves Chronic Plaque Psoriasis
Researchers at the Icahn School of Medicine report that roflumilast cream (ARQ-151), which contains a highly potent, selective phosphodiesterase-4 (PDE4) inhibitor demonstrated significant improvements in patients with psoriasis signs and symptoms in as early as two weeks. The phase 2b trial results showed that when patients with plaque psoriasis applied topical roflumilast once-daily they reported clear skin as well as improvement in itch and burden of disease. The results of the paper were published online today in The New England Journal of Medicine.
5 TIPS TO IMPROVE NAIL PSORIASIS AT HOME
Approximately 7.5 million people in the U.S. have psoriasis, a chronic inflammatory disease that mostly affects the skin and joints but could also affect the nails. According to dermatologists from the American Academy of Dermatology, most people who have plaque psoriasis — the most common form of psoriasis — also develop nail psoriasis at some point. This is why dermatologists say it’s important for psoriasis patients to check their nails — both their fingernails and toenails — for signs of nail psoriasis, which can include nail dents, lifting, discoloration, thickening and crumbling. However, it’s also possible for patients to experience nail psoriasis without having psoriasis on other parts of their body.
Researchers Identify Mechanisms That Make Skin a Protective Barrier
Study Could Help Doctors Understand and Treat Common Conditions