U.S. Drug-related Infant Deaths More than Doubled from 2018 to 2022

Drug-involved infant deaths more than doubled (120% increase) from 2018 to 2022, with the greatest proportion of deaths in 2021 (25.8%). The most prevalent underlying causes of death included assault (homicide) by drugs, medicaments and biological substances (35.6%).

How Scientists Are Accelerating Chemistry Discoveries With Automation

Researchers have developed an automated workflow that could accelerate the discovery of new pharmaceutical drugs and other useful products. The new approach could enable real-time reaction analysis and identify new chemical-reaction products much faster than current laboratory methods.

Endometriosis Awareness Month: Answers to Frequently Asked Questions

It is one of the most common and painful disorders, affecting more than 6 million women in the United States. Endometriosis is often difficult to diagnose and effectively treat. But Cedars-Sinai experts find patients can now benefit from minimally invasive procedures, medications and integrative medicine.

Good News—MS Drugs Taken While Breastfeeding May Not Affect Child Development

Certain medications for multiple sclerosis (MS) called monoclonal antibodies, taken while breastfeeding, may not affect the development of a child during the first three years of life, according to a preliminary study released today, March 4, 2024. The study will be presented at the American Academy of Neurology’s 76th Annual Meeting taking place April 13–18, 2024, in person in Denver and online. The study examined four monoclonal antibodies for MS: natalizumab, ocrelizumab, rituximab and ofatumumab.

SMART Recovery Meetings for Alcohol Recovery Appeal to People with More Social and Economic Stability and Lower Spiritual Leanings, Compared to Alcoholics Anonymous

Certain characteristics of people seeking remission from alcohol use disorder (AUD) are linked to their choice of recovery meeting, a new study suggests. Informal peer recovery groups—mutual-help organizations—play a crucial role for many individuals with AUD or other drug disorders. Such groups are proliferating and differ substantially in approach.

As “deprescribing” medicines for older adults catches on, poll shows need for patient-provider dialogue

As the movement toward “deprescribing” medications among older adults grows, a new poll shows strong interest in this idea, with 80% of adults aged 50 to 80 open to stopping one or more of the prescription medicines they’ve been taking for more than a year, if a health care provider said it was possible. Already, 26% said they have done so in the past two years – though some had done it without talking to a health provider.

Immune from Chronic Stress? Limit Inflammatory Signaling to Specific Brain Circuits

Chronic stress is associated with the pathogenesis of psychological disorders such as depression. A study is the first to identify the role of a neuronal receptor that straddles the intersection between social stress, inflammation, and anxiety in rodent models of stress. Findings suggest the possibility of developing better medications to treat the consequences of chronic stress by limiting inflammatory signaling not just generally, which may not be beneficial in the long run, but to specific brain circuits.