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UrduWhen you pick up a prescription or get a vaccination, it’s paramount that you trust the medication is safe. In the U.S., a system of laws, procedures, and personal responsibility combine to ensure drug safety, or pharmacovigilance.
Tag: Drug Safety
Navigating the risks: safeguarding maternal and fetal health in emergency agitation treatment
A recent review article provides critical insights into the management of acute agitation in reproductive-age females and during pregnancy within the emergency departments (EDs).
Toxic metal particles can be present in cannabis vapes even before the first use
Vapes are thought to be a “safer” way to consume cannabis, but they present their own risks. Researchers have discovered toxic metal particles in vaping liquids even before first use of the device, and this toxicity was worse in illicit products. They will present their results at ACS Spring 2024.
A step to prevent opioid overdose deaths with light-activated naloxone treatment
In a proof-of-concept in ACS’ Nano Letters, a team has designed injectable nanoparticles that released naloxone ― which rapidly reverses opioid overdose effects ― when triggered by blue light. In experiments with mice, this system was activated a month after injection.
Tiny model organs detect liver toxicity of new drugs
A University of Michigan-led study provided evidence of the efficacy of a new drug-induced liver injury screening platform using human liver organoids, or tiny 3D models of organs developed from patients’ stem cells that grow in petri dishes.
New tool reveals how drugs affect men, women differently — and will make for safer medications
UVA Health researchers have developed a powerful new tool to understand how medications affect men and women differently, and that will help lead to safer, more effective drugs in the future.
NCCN Senior Director Evelyn Handel Zapata is Named a ‘40 Under 40 in Cancer: Emerging Leader’ for Milestone Work Improving Safe Use of Chemotherapy
Evelyn Handel Zapata, PharmD, BCPS, BCOP, Senior Director of Drugs & Biologics Programs at the National Comprehensive Cancer Network® (NCCN®) was named a 40 Under 40 in Cancer: Emerging Leader; launches new resources for a type of pediatric lymphoma.
The pandemic a tough time also for pharmacies
Customers showing up even when they were sick, not agreeing with the restrictions, and many new tasks for staff. These are factors that contributed to heavier workloads and tougher work environments in pharmacies during the pandemic, a study reveals.
Fatal overdoses increase after police seize drugs, study finds
For decades, efforts by police to seize illicit drugs have been a cornerstone strategy for disrupting drug markets and removing drugs from communities. But there’s an unintended outcome when opioids are seized, a new study finds — increases in overdoses, including those that are fatal.
Children are ditching alcohol for marijuana, as 20-year national US study shows a 245% increase
Adolescent cannabis abuse has increased 245% since 2000 in the US, while alcohol abuse has steadily declined over the same period.
Psychiatrists disagree with U.S. policy on psychoactive drugs
A new national survey reveals considerable differences between psychiatrists’ perceptions about the safety and therapeutic value of certain psychoactive drugs and how those same drugs are categorized under U.S. policy.
Sensor could help patients stay on top of their meds
Lithium needs to be taken in just the right amount to be effective. Today, scientists report the development of a tiny sensor that detects lithium levels noninvasively from sweat on a fingertip in about 30 seconds. The researchers will present their results at ACS Fall 2022.
Medicare Program Spent $1.8 Billion in 2019 on Drugs Without Confirmed Clinical Benefits
Study found that some drugs were on the market for over five years with no confirmed clinical benefit.
WFIRM and Oracle Health Sciences collaborate to pair Body-on-a-Chip with advanced data analytics
The Wake Forest Institute for Regenerative Medicine (WFIRM) and Oracle Health Sciences have teamed as part of the Innovation Quarter’s iQ Healthtech Labs™ to develop a consortium of industry, government, and academic members that will study novel approaches to establishing the safety of new drugs that are nearing clinical investigation in humans and FDA approval.
Predicting Side Effects
At a glance:
• Scientists develop AI-based tool to predict adverse drug events
• Such events are responsible for some 2 million U.S. hospitalizations per year
• The free, open-source system could enable safer drug design, optimize drug safety
Xenobiotic Receptor Activation, CRISPR/Cas9, Magnetic Resonance-Guided Radiotherapy, and More Featured in May 2020 Toxicological Sciences
During these difficult times, the Society of Toxicology’s official journal, Toxicological Sciences, remains a source for leading research in toxicology, including in the areas of biomarkers, carcinogenesis, and organ-specific toxicology.