A First Look at Cedars-Sinai Guerin Children’s

Inside the new, 23,000-square-foot Guerin Children’s, walls are painted in cheerful yellows, greens and blues. Artificial skylights are timed to brighten and darken as the sun rises and sets. Interactive-art installations feature whimsical characters, and a playroom and family lounge area contribute to the playful energy of the space.

A Lifetime of Heart Care Leads to Transplant

While many 21-year-olds celebrate their coming of age in bars and nightclubs, Andrew Solis is celebrating freedom by finally going home—equipped with a new heart and liver—after nearly eight months at Cedars-Sinai.

Hormones Contribute to Sex Disparities in Bladder Cancer, Study Shows

Male sex hormones interfere with the body’s ability to fight bladder cancer, likely explaining why males experience higher cancer rates and more deadly disease, according to a new study co-led by a Cedars-Sinai Cancer investigator.

First-of-its-Kind Stem Cell and Gene Therapy Highlighted at Annual Stem Cell Meeting

Investigators from Cedars-Sinai will present the latest novel stem cell and regenerative medicine research at the International Society for Stem Cell Research (ISSCR) Annual Meeting, which is being held in person and virtually June 15-19 in San Francisco.

Path to Remission for a Brain Cancer That Is Usually Fatal

Recently, Michael Wulfe, who is 61 and lives in West Hollywood, was on the phone with his sister, Stephanie Wulfe, in Dallas. They talk at least once a day, but that day, something wasn’t right. “I was talking, and then I didn’t have the words,” Wulfe said. “My sister immediately said, ‘Call Cedars-Sinai!’”

National Leader in Cardiac Surgery Quality and Research Joins Cedars-Sinai

Michael Bowdish, MD, MS, a national leader in cardiac surgery and among a handful of cardiac surgeons continuously funded by the National Institutes of Health for a decade, has been appointed vice chair of the Department of Cardiac Surgery in the Smidt Heart Institute.

ASCO22: Lung Cancer Therapy Could Help Patients Live Longer

Results of a Phase II clinical trial led by Cedars-Sinai Cancer investigators indicate that an immunotherapy drug combination could extend the lives of those diagnosed with advanced non-small cell lung cancer, one of the most common forms of lung cancer. The research was presented today during the American Society of Clinical Oncology (ASCO) annual meeting in Chicago, with simultaneous publication in the peer-reviewed Journal of Clinical Oncology.

ENDO 2022 to Feature Cedars-Sinai Physicians and Scientists

Physicians and scientists from Cedars-Sinai will discuss the latest advances in treatment, care and research at the Endocrine Society’s annual meeting (ENDO 2022) in Atlanta, June 11-14.

Brain Cell Activity Plays Critical Role in CNS Disorder Outcomes

Investigators at Cedars-Sinai have comprehensively mapped molecular activity in the brain and spinal cord that is responsible for regulating the body’s response to central nervous system (CNS) disorders such as Alzheimer’s, Huntington’s disease and spinal cord injuries.

SpaceX CRS-25 to Launch Stem Cells to Space on June 9

Cedars-Sinai and Space Tango are launching pilot-scale systems for the in-space production of stem cells to see if they can elevate the next generation of stem cell and gene therapies by harnessing the near-zero gravity conditions of spaceflight.

Cedars-Sinai Investigators ID Gene Critical to Human Immune Response

Cedars-Sinai investigators have identified a gene that plays an essential role in the innate human immune system. The gene, NLRP11, helps activate the inflammatory response that tells the body’s white blood cells to go on the attack against a foreign presence.

Cedars-Sinai Cancer Experts Present Breakthroughs at 2022 ASCO Annual Meeting

Experts from Cedars-Sinai Cancer, ranked among the top 10 in the nation for cancer care, will present novel research and clinical advances throughout the 2022 annual meeting of the American Society of Clinical Oncology (ASCO), taking place in person and virtually June 3-7 in Chicago.

May Research Highlights

A Roundup of the Latest Medical Discoveries and Faculty News at Cedars-Sinai

MONKEYPOX MEDIA ADVISORY: Infectious Disease Specialists From Regional Special Pathogen Treatment Center Available to Discuss Monkeypox Causes and Treatments

Multiple cases of monkeypox have surfaced in Europe and the U.S. that do not appear to be linked to travel, causing concern among the medical community that this infectious disease is spreading through sexual contact or other close interactions.

New Combined Therapy Helps Extend Lives of Men With Prostate Cancer

Practice-changing research from Cedars-Sinai Cancer shows that a combination of androgen deprivation therapy—a commonly used hormone injection—plus pelvic lymph node radiation, kept nearly 90% of clinical trial patients’ prostate cancer at bay for five years. The findings were published in the peer-reviewed journal The Lancet.

Cedars-Sinai’s Dean, Shlomo Melmed, MB, ChB, Honored for Contributions to Endocrine Research

Shlomo Melmed, MB, ChB, a world-renowned leader in pituitary medicine, was named the inaugural recipient of the Transatlantic Alliance Award by the European Society of Endocrinology (ESE) and the Endocrine Society for his pioneering research in pituitary medicine and endocrine tumors.

Study: App More Accurate Than Patient Evaluation of Stool Samples

An innovative mobile phone application was found to be as good as expert gastroenterologists at characterizing stool specimens, according to a study by Cedars-Sinai. The artificial intelligence (AI) used in the smartphone app also outperformed reports by patients describing their stool specimens.

Cedars-Sinai Offers Program to Catch Older Adults Before They Fall

Falls and broken bones are common among older adults, but they’re not a natural part of aging. That’s why Cedars-Sinai geriatricians created a bone health and falls risk consultation program to catch at-risk people before they break a bone or help them avoid another fracture in the future.

Cedars-Sinai Experts to Present New Research and Discuss Advances in Care for Older Adults

Cedars-Sinai geriatrics experts will present their latest advances in research and care in person at the annual scientific meeting of the American Geriatrics Society (AGS) in Orlando May 12-14, sharing innovations to improve both the quality of patient care and quality of life for older adults.

Supportive Care for Neurology Patients

In June of 2021, retired nurse Linda Leaming, 70, of LaVerne, was admitted to Cedars-Sinai after suffering a stroke. She was delirious and refusing to eat and drink, and her husband, Rich Leaming, struggled with decisions about her care. Neuropalliative specialist Jessica Besbris, MD, director of Neuropalliative Care and the Neurology Supportive Care Medicine Program at Cedars-Sinai, came to his aid.

April Research Highlights

This tipsheet highlights the latest medical discoveries and faculty news at Cedars-Sinai. Links to full news releases are included with each item.

Cardiologists, Cardiothoracic Surgeons Available for Expert Commentary Ahead of Upcoming Conferences

Cardiologists and cardiothoracic surgeons from the Smidt Heart Institute at Cedars-Sinai are available to discuss the latest advances in research, clinical care, transcatheter procedures and cardiothoracic surgery throughout the International Society for Heart and Lung Transplantation (ISHLT) Scientific Sessions 2022 and Heart Rhythm 2022.

AI May Detect Earliest Signs of Pancreatic Cancer

An artificial intelligence (AI) tool developed by Cedars-Sinai investigators accurately predicted who would develop pancreatic cancer based on what their CT scan images looked like years prior to being diagnosed with the disease. The findings, which may help prevent death through early detection of one of the most challenging cancers to treat, are published in the journal Cancer Biomarkers.

Smidt Heart Institute: Annual Report Highlights

The 2022 Annual Report from the Smidt Heart Institute at Cedars-Sinai is available now, detailing the latest research and medical achievements by the expert team ranked No. 1 for cardiology and cardiac surgery in California by U.S. News & World Report.

Cedars-Sinai Gifted $10M to Create Memory and Aging Program

Cedars-Sinai announced today a $10 million gift to establish the Bernard and Maxine Platzer Lynn Family Memory and Healthy Aging Program in the Department of Neurology. The program will broaden the scope of age-related care at Cedars-Sinai—with a focus on healthy aging, patient independence, care coordination, and brain health.

A Patient Pioneer: Minimally Invasive Lung Transplantation

To anyone else, it’s just a walk around the block. But for Frank Coburn, 57, and his wife, it’s a miracle. A miracle that resulted from Coburn becoming the first Southern Californian—and possibly first in the U.S.—to receive a minimally invasive double lung transplant. The procedure was performed at the Smidt Heart Institute.

Even During Pandemic, Volunteers Bring Comfort

The Ruth and Harry Roman Emergency Department at Cedars-Sinai sees more than 85,000 patients each year. Among the first to greet those patients and their loved ones–even during the coronavirus pandemic–are Cedars-Sinai’s blue-coated volunteers, who are honored this week during National Volunteer Appreciation Week.

Irritable Bowel Syndrome: Mark Pimentel, MD

Irritable bowel syndrome (IBS) is the most common gastrointestinal disorder, affecting 10-15% of the world’s population. Approximately two-thirds of those who suffer from IBS are women. The disease can have mild forms or cause severe debilitation as diarrhea alternates with constipation. Severe cramping and bloating also are common. Because chronic IBS is so debilitating, it often disrupts the daily lives of people with this disorder.

Study: New Approach May Boost Prostate Cancer Immunotherapies

Researchers have discovered a new way to transform the tissues surrounding prostate tumors to help the body’s immune cells fight the cancer. The discovery, made in human and mouse cells and in laboratory mice, could lead to improvements in immunotherapy treatments for prostate cancer, the second most common cancer in men in the U.S.

Cedars-Sinai Demo Day Goes Virtual

The COVID-19 pandemic has brought unprecedented innovation on the part of healthcare providers everywhere who rose to meet the challenges of the past year.

And the next generation of healthcare innovations will be on display during the Cedars-Sinai Accelerator Demo Day, on Wednesday, April 7, from 3:30-5 p.m. Click here to register to attend the virtual event.