Three recently published studies from Cedars-Sinai investigators have deepened knowledge of how changes in the eye are linked to indicators of Alzheimer’s disease in the brain.
Tag: Cedars-Sinai investigators
Patterns of Intelligence
The coordinated activity of brain cells, like birds flying in formation, helps us behave intelligently in new situations, according to a study led by Cedars-Sinai investigators.
Can Deep Brain Stimulation Help More Patients?
Deep brain stimulation procedures use electrical pulses to disrupt tiny portions of the brain and halt epileptic seizures or disease-related tremor. The therapy is invaluable, but the basic technology has not advanced in decades.
New Studies: AI Captures Electrocardiogram Patterns That Could Signal a Future Sudden Cardiac Arrest
Two new studies by Cedars-Sinai investigators support using artificial intelligence (AI) to predict sudden cardiac arrest—a health emergency that in 90% of cases leads to death within minutes.
Study Details How a Common Bacterium Resists New Antibiotic
Cedars-Sinai investigators have detailed a new way that bacteria use iron to cooperate and resist antibiotic treatment. The study, led by the Cedars-Sinai departments of Biomedical Sciences and Pathology and Laboratory Medicine, is published in the peer-reviewed journal Nature Microbiology and is the first to show this type of antibiotic cross-protection.
New Cedars-Sinai Study Pinpoints Why Some Injured Kidneys Do Not Heal
Cedars-Sinai investigators have discovered why some injured kidneys heal while others develop scarring that can lead to kidney failure. Their findings, detailed in a paper published in the peer-reviewed journal Science, could lead to the development of noninvasive tests to detect kidney scarring and, eventually, new therapies to reverse the condition.
Why the Top Cause of Death for Women Has Been Ignored
Experts at the Smidt Heart Institute at Cedars-Sinai who have studied progress made over decades of research say there’s still a long way to go before medical science fully understands how heart disease is different in women than men.
How Air Pollution Accelerates Alzheimer’s Disease
Investigators from the Department of Neurosurgery at Cedars-Sinai have determined that exposure to polluted air could accelerate development of Alzheimer’s disease in those with genetic risk factors for the neurodegenerative condition.
Fiber, the Gut, Heart Disease and HIV
Investigators from Cedars-Sinai have made two important discoveries about fiber and the gut microbiome in patients with human immunodeficiency virus, or HIV.
Cedars-Sinai Infectious Disease Experts Featured at IDWeek Meeting
Cedars-Sinai infectious disease specialists and investigators will present research and discuss clinical advances throughout IDWeek, taking place in Boston from Oct. 11-15.
Redo Transcatheter Aortic Valve Replacement Proven Effective, Safe
Cedars-Sinai investigators are leaders in the innovation and use of transcatheter aortic valve replacement (TAVR) with balloon-expandable valves. They now show that redo TAVR procedures are both safe and effective when compared with situations in which patients with similar risk profiles undergo the same procedure for the first time.
Belly Fat Hinders Digestive Disease Medications
The mass and composition of our bodies can significantly affect the way medications are metabolized and absorbed. Investigators at Cedars-Sinai found that inflammatory bowel disease (IBD) patients with higher levels of intra-abdominal visceral adipose tissue– a distinctive type of fat inside the abdomen −had lower rates of remission when treated with certain anti-inflammatory medications.
Study Identifies How Diabetes Slows Healing in the Eye
Investigators from Cedars-Sinai have provided new understanding of how diabetes delays wound healing in the eye, identifying for the first time two related disease-associated changes to the cornea.
COVID-19 Vaccination Reduced Disease Disparities Between Low- and High-Income Communities
COVID-19 vaccination helped reduce disparities in disease incidence between low- and high-income communities, according to a new analysis led by Cedars-Sinai investigators.
Adverse Pregnancy Outcomes Increase Stroke Risk
Investigators from the Smidt Heart Institute at Cedars-Sinai found that women who experience an adverse pregnancy outcome—such as gestational hypertension, preeclampsia or preterm birth—have a higher risk of developing stroke in their lifetime, and at a younger age.
Study: Blood Vessel Damage Could Be an Alzheimer’s Driver
Blood vessel abnormalities in the eye are a major factor in the progression of Alzheimer’s disease, according to research from Cedars-Sinai investigators published in the peer-reviewed journal Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association.
Study Gives Insight Into Cause of Severe Inflammatory Bowel Disease
Cedars-Sinai investigators have identified a genetic variant that increases people’s risk of developing perianal Crohn’s disease, the most debilitating manifestation of Crohn’s disease.
Mission Ax-2 Set to Launch Stem Cells to Space
Cedars-Sinai investigators, in collaboration with Axiom Space of Houston, are sending stem cells to space in early May to explore whether microgravity can make it easier and more efficient to produce large batches of stem cells.
Is Artificial Intelligence Better at Assessing Heart Health?
Who can assess and diagnose cardiac function best after reading an echocardiogram: artificial intelligence (AI) or a sonographer?
Study: ChatGPT Has Potential to Help Cirrhosis, Liver Cancer Patients
A new study by Cedars-Sinai investigators describes how ChatGPT, an artificial intelligence (AI) chatbot, may help improve health outcomes for patients with cirrhosis and liver cancer by providing easy-to-understand information about basic knowledge, lifestyle and treatments for these conditions.
Risk of Sudden Cardiac Arrest Rises Sharply in Ventura County
In a study among residents of Ventura County, California, rates of sudden cardiac arrest rose sharply during the COVID-19 pandemic.
The Shape of Your Heart Matters
Curious to know if you’re at risk for two common heart conditions? Your doctor may want to check the shape of your heart.
Where Does Your Brain Want to Have Lunch?
New research published by investigators at Cedars-Sinai advances scientific understanding of how the brain weighs decisions involving what people like or value, such as choosing which book to read, which restaurant to pick for lunch—or even, which slot machine to play in a casino.
Study Reveals New Understanding of How Androgen Therapy Affects Breast Tissue
New insights into the effects of a hormonal treatment for transgender men, discovered by Cedars-Sinai investigators, could have implications for the treatment of breast cancer.
New Insights: Eye Damage in Alzheimer’s Disease Patients
Cedars-Sinai investigators have produced the most extensive analysis to date of changes in the retina—a layer of tissue at the back of the eye where visual information originates—and how those retinal changes correspond to brain and cognitive changes in Alzheimer’s disease patients.
Verified: COVID-19 Infection Increases Diabetes Risk
Investigators in the Smidt Heart Institute at Cedars-Sinai have confirmed that people who have had COVID-19 have an increased risk for new-onset diabetes—the most significant contributor to cardiovascular disease.
Investigators Closer to Predicting 2 Common Heart Conditions
Two novel research studies from Cedars-Sinai move the needle on predicting two important heart conditions—sudden cardiac arrest, which is often fatal, and increased coronary artery calcium, a marker of coronary artery disease that can lead to a heart attack.
Mapping Endometriosis: A Vast Cellular Atlas Is Created
Investigators at Cedars-Sinai have created a unique and detailed molecular profile of endometriosis to help improve therapeutic options for the millions of women suffering from the disease.
Mediterranean Diet Linked to Lower Preeclampsia Risk
In a new study evaluating the Mediterranean diet and adverse pregnancy outcomes, investigators from the Smidt Heart Institute at Cedars-Sinai found that women who conceived while adhering to the anti-inflammatory diet had a significantly lower risk of developing preeclampsia during pregnancy.
Noteworthy Medical Research Discoveries From 2022
Investigators at Cedars-Sinai conduct more than 2,500 research projects annually, and many of these studies have resulted in new treatments or have opened the door to future innovations.
Immune System Irregularities Found in Women With Postpartum Mood Disorders
Women with prolonged mental health problems up to three years after childbirth may be suffering from irregular immune system responses, according to new research by Cedars-Sinai investigators. The findings are published in the American Journal of Reproductive Immunology.
Bloating Common Issue Among Americans, Study Reports
Nearly 1 in 7 Americans experience bloating on a weekly basis, and most aren’t seeking professional care for it, according to a new study led by Cedars-Sinai investigators. The findings are published in Clinical Gastroenterology and Hepatology.
Study: Which People With Chronic Pancreatitis Will Develop Diabetes?
A new study by Cedars-Sinai investigators describes risk factors that could make it more likely for people who have chronic pancreatitis, an ongoing inflammation of the pancreas, to develop diabetes. The findings are published in Diabetes Care.
Study: During Pandemic, High Blood Pressure Control Declined
Hypertension control and management worsened during the early months of the COVID-19 pandemic, according to a new analysis conducted at three large health systems, led by Cedars-Sinai investigators.
Some Healthcare Workers Produced a Low Response to COVID-19 Vaccinations in a Study by Cedars-Sinai
A subset of healthcare workers vaccinated against COVID-19 had unexpectedly low responses to the immunizations, according to Cedars-Sinai investigators. The findings of the new study are published in iScience, a Cell Press journal.
Tipsheet: Cedars-Sinai Digestive Disease Experts Share Latest Research and Honors at the ACG 2022 Scientific Meeting
Cedars-Sinai physicians and scientists will share the results of new research aimed at improving the treatment of digestive diseases during the international meeting of the American College of Gastroenterology (ACG). The clinical conference will take place Oct. 21-26 in Charlotte, North Carolina, and is available for virtual and in-person attendance.
HER2 Pathways in Breast Cancer May Hold Key to Effective Treatment of Idiopathic Pulmonary Fibrosis
LOS ANGELES (Oct. 13, 2022) — FINDINGS A new study led by Cedars-Sinai investigators suggests HER2 signaling may be a key driver of fibroblast invasion and can serve as a target for therapeutic intervention in idiopathic pulmonary fibrosis. HER2 is…
Gut Gases Linked to Specific Types of Irritable Bowel Syndrome
A new study led by Cedars-Sinai investigators found using breath tests to identify gut gas profiles can potentially help lead to more personalized therapies for people diagnosed with irritable bowel syndrome (IBS). The most common gastrointestinal disorder affects 10% to15% of the world’s population.
Cedars-Sinai Study Highlights Cancer Disparities in LA County
People in Los Angeles County experience differences in cancer risk and survival depending on a variety of factors such as race/ethnicity, gender, sexual orientation, geographic location and socioeconomic status, according to a new study by investigators at Cedars-Sinai Cancer.
Stem Cell-Gene Therapy Shows Promise in ALS Safety Trial
Cedars-Sinai investigators have developed an investigational therapy using support cells and a protective protein that can be delivered past the blood-brain barrier. This combined stem cell and gene therapy can potentially protect diseased motor neurons in the spinal cord of patients with amyotrophic lateral sclerosis, a fatal neurological disorder known as ALS or Lou Gehrig’s disease.
Hyperactivation of the Immune System May Cause Post-COVID Syndromes
Investigators at Cedars-Sinai have proposed a theory for how SARS-CoV-2, the virus that causes COVID-19, infects the body. Their hypothesis, published in Frontiers in Immunology, could explain why some people still have symptoms long after the initial infection.
New Method Detects Gut Microbes That Activate Immune Cells
Cedars-Sinai investigators have developed a method to help identify which human gut microbes are most likely to contribute to a slew of inflammatory diseases like obesity, liver disease, inflammatory bowel disease, cancer and some neurological diseases.
First-of-its-Kind Stem Cell and Gene Therapy Highlighted at Annual Stem Cell Meeting
Investigators from Cedars-Sinai will present the latest novel stem cell and regenerative medicine research at the International Society for Stem Cell Research (ISSCR) Annual Meeting, which is being held in person and virtually June 15-19 in San Francisco.