A simple blood test could help doctors identify women in labor who are at risk for preeclampsia — a leading cause of maternal death — and take precautions to prevent it, according to research presented at the ANESTHESIOLOGY® 2024 annual meeting.
Tag: Preeclampsia
UNDER EMBARGO: Mount Sinai Study Identifies Link Between Prediabetes During Adolescence and Young Adulthood With the Likelihood of Adverse Pregnancy Outcomes
New paper finds that prediabetes before conception may significantly increase the likelihood of gestational diabetes during first pregnancy
Blocking Key Protein Normalizes Uterine Muscle Tone
Rockville, Md. (June 10, 2024)—Abnormal uterine blood flow is a hallmark of hypertensive disorders of pregnancy, including chronic hypertension, preeclampsia and gestational hypertension. Abnormal uterine blood flow is also associated with a low fertility rate. However, the mechanisms controlling uterine…
Mount Sinai Experts to Present New Research on Preeclampsia, Preterm Birth, Doula Care and More at the 2024 ACOG Annual Clinical and Scientific Meeting
Women’s health doctors and researchers will share new insights on prenatal care
Women’s Health Month: Artificial Intelligence Can Improve OB-GYN Care
Cedars-Sinai investigators are using artificial intelligence (AI) to reduce serious health risks associated with pregnancy and childbirth and improve screening for some gynecological cancers.
Benefits of Quitting Cigarettes During Pregnancy Exceed Dangers of Weight Gain
A Rutgers Health study ties quitting to more hypertensive disorders but fewer premature deliveries and stillbirths.
Why the Top Cause of Death for Women Has Been Ignored
Experts at the Smidt Heart Institute at Cedars-Sinai who have studied progress made over decades of research say there’s still a long way to go before medical science fully understands how heart disease is different in women than men.
RUDN doctors found a mechanism of preeclampsia development
RUDN University doctors studied immunohistochemical markers in patients with normal pregnancy and preeclampsia and noticed patterns.
Mount Sinai Receives $4.6 Million From The Pershing Square Foundation to Support Women’s Health Research and Careers for Women in Science
The Icahn School of Medicine at Mount Sinai has received a $4.6 million gift from The Pershing Square Foundation to support women’s health research and advance careers for female scientists
Faster growth of the placenta is linked to increased risk of preeclampsia
Research sheds light on how genetics influences the growth of the placenta and reveals a link to increased risk of disease in the mother.
In major breakthrough, researchers close in on preeclampsia cure
Researchers from Western and Brown University have made groundbreaking progress towards identifying the root cause and potential therapy for preeclampsia.
Mitochondrial Changes Linked to High Blood Pressure in Pregnancy
A new study provides evidence for the possibility that mitochondrial dysregulation could be a contributing factor in the development of hypertensive disorders of pregnancy. The study is published in Physiological Genomics. It was chosen as an APSselect article for July.
Health Experts Address Alarming Disparities in Black Maternal Health
Experts from Cedars-Sinai, BlackDoctors.org, the California Black Women’s Health Project and the Morehouse School of Medicine participated in a recent discussion that addressed the high rate of pregnancy-related deaths among Black mothers.
Postpartum morbidity and mortality in women with epilepsy: A 28-year study
A 28-year study found increased risks of preeclampsia, gestational diabetes, ICU admission during hospitalization for delivery, postpartum hospitalization, and an increased risk of mortality compared with pregnant women who did not have epilepsy.
Spotlight: Maternal Mental Health Month
Most new mothers experience one or more changes in their mood before childbirth and for two weeks after the baby arrives.
Cedars-Sinai Study: Biomarkers That Predict Preeclampsia Risk
In a study of pregnant women in the United States, Cedars-Sinai investigators found that a specific imbalance of two placental proteins could predict which women were at risk of developing a severe form of preeclampsia, a life-threatening blood pressure disorder.
La preeclampsia se relaciona con indicadores de alto riesgo para daño e inflamación en células cerebrales
Según los investigadores de Mayo Clinic, las mujeres con antecedentes de preeclampsia grave tienen más indicadores de un mayor riesgo de sufrir daño e inflamación en las células del cerebro en comparación con aquellas que tuvieron embarazos sin complicaciones.
Preeclampsia linked to increased markers of brain cell damage, inflammation
Preeclampsia is a serious complication of pregnancy characterized by high blood pressure and kidney damage. Mayo Clinic researchers found that women with a history of severe preeclampsia have more markers linked to brain cell damage and inflammation, compared to women who had uncomplicated pregnancies.
Treating Moderately Elevated Blood Pressure During Pregnancy
The Chief of Maternal-Fetal Medicine at Rutgers Robert Wood Johnson Medical School discusses a practice-changing study he coauthored
Past Kidney Disease May Increase Preeclampsia Risk, Impair Blood Vessel Health during Pregnancy
A history of kidney problems may put people at a higher risk for impaired blood vessel function, which could lead to high blood pressure, preterm labor and other adverse outcomes, according to the results of a study in rats. The researchers will present their work this week at the American Physiological Society (APS) and American Society for Nephrology Control of Renal Function in Health and Disease conference in Charlottesville, Virginia.
Study: Mediterranean-Style Diet Further Linked to Reduced Risk of Preeclampsia in Pregnant Women of All Races
A new Johns Hopkins Medicine study that surveyed a racially diverse group of more than 8,000 women has added to evidence that following a Mediterranean-style diet could lower the risk of preeclampsia by at least 20%.
COVID-19 infection increases risk for preeclampsia reported by WSU and PRB investigators
A newly published study found that women who contract COVID-19 during pregnancy are at significantly higher risk of developing pre-eclampsia, the leading cause of maternal and infant death worldwide.
Enzyme Could Be Major Driver of Preeclampsia
A new study by UT Southwestern scientists indicates that an enzyme called protein phosphatase 2 (PP2A) appears to be a major driver of preeclampsia, a dangerous pregnancy complication characterized by the development of high blood pressure and excess protein in the urine. The finding, published in Circulation Research, could lead to new treatments for preeclampsia other than premature delivery, which is often the only option.
Hopkins Med News Update
News stories in this issue
Rat Model of Preeclampsia Gives new Insight into Immunological Changes during Pregnancy
Article title: Immunological comparison of pregnant Dahl salt-sensitive and Sprague-Dawley rats commonly used to model characteristics of preeclampsia Authors: Erin B. Taylor, Eric M. George, Michael J. Ryan, Michael R. Garrett, Jennifer M. Sasser From the authors: “The current study…
Association between Hypertension and Gut Microbiome Imbalance during Pregnancy May Lead to New Preeclampsia Treatments
Article title: Gestational gut microbial remodeling is impaired in a rat model of preeclampsia superimposed on chronic hypertension Authors: Jeanne A. Ishimwe, Adesanya Akinleye, Ashley C. Johnson, Michael R. Garrett, Jennifer M. Sasser From the authors: “These results reveal an…
Exposure to Vitamin D in the Womb Might Minimize Risk of High Blood Pressure for Children Born to Mothers with Preeclampsia
Children appear to be at greater risk of having high blood pressure when their mothers had the high blood pressure condition called preeclampsia during pregnancy—but this adverse association may be reduced or even eliminated for children who were exposed to higher levels of vitamin D in the womb.
Placental Release of Iron Affects Post-birth Nitric Oxide Balance
Article title: Evidence for placental-derived iron-nitrosyls in the circulation of the fetal lamb and against a role for nitrite in mediating the cardiovascular transition at birth Authors: Arlin B. Blood, Taiming Liu, George Mukosera, Shawn F. Hanson, Michael H. Terry, Hobe…
High blood pressure during pregnancy may mean worse hot flashes during menopause
Women with a history of high blood pressure disorders during pregnancy are more likely to experience bothersome menopausal symptoms such as hot flashes and night sweats, according to a study published Wednesday, Aug. 19, in Menopause: The Journal of the North American Menopause Society.
Maternal obesity increases risk of potentially deadly hypertensive disorders early in pregnancy
Pregnant obese women were more at risk of experiencing early and late-onset hypertensive disorders, and that risk progressively increased in women with higher body mass indexes (BMI), according to a study led by researchers at UTHealth.
Higher Manganese Levels in Early Pregnancy Linked to Lower Preeclampsia Risk
An analysis of data from more than 1,300 women followed prospectively through pregnancy found that women with lower levels of the essential mineral manganese in early pregnancy were more likely to develop the serious high blood pressure syndrome called preeclampsia in late pregnancy.
Pregnancy Complications in Assisted Reproduction Linked to a Specific Process
An experimental study from researchers in the Perelman School of Medicine at the University of Pennsylvania links a specific procedure – embryo culture – that is part of the assisted reproduction process (ART) to placental abnormalities, risk for preeclampsia, and abnormal fetal growth. The team, led by Marisa Bartolemei, PhD, a professor of Cell and Developmental Biology, published their findings today in Development.
RNA Molecules in Maternal Blood May Predict Pregnancies at Risk for Preeclampsia
UC San Diego researchers have identified small molecules in the blood of asymptomatic pregnant women that may predict risk for preeclampsia, responsible for a significant proportion of maternal and neonatal deaths, low birth weight and is a primary cause of premature birth.
Pregnant Women with Very High Blood Pressure Face Greater Heart Disease Risk
Women with preeclampsia are four times more likely to suffer a heart attack or cardiovascular death, Rutgers study finds
Rutgers Expert Available to Discuss Global Fisheries Management Study
New Brunswick, N.J. (Jan. 13, 2020) – Rutgers University–New Brunswick Professor Olaf P. Jensen is available for interviews on new marine fisheries management research to be published in the journal Proceedings of the National Academy of Sciences. The study is the most comprehensive…
Early Diagnosis of Pregnancy-Associated Heart Disease Linked to Significantly Better Outcomes
Women who are diagnosed with peripartum cardiomyopathy (PPCM) during late pregnancy or within a month following delivery are more likely to experience restored cardiac function and improved outcomes compared to those who are diagnosed later in the postpartum period.