Flozin Drugs Lower Salt-Induced Hypertension, Maintain Circadian Rhythm in Rats

Article title: SGLT2 inhibition effect on salt-induced hypertension, RAAS and Na+ transport in Dahl SS rats Authors: Olha Kravtsova, Ruslan Bohovyk, Vladislav Levchenko, Oleg Palygin, Christine A. Klemens, Timo Rieg, Alexander Staruschenko From the authors: “The main findings of the…

Intermittent Fasting Protects Kidneys of Obese Mice

New research in mice finds that time-restricted feeding improves markers of kidney and vascular health. The research will be presented this week at the American Physiological Society and American Society for Nephrology Control of Renal Function in Health and Disease conference.

Past Kidney Disease May Increase Preeclampsia Risk, Impair Blood Vessel Health during Pregnancy

A history of kidney problems may put people at a higher risk for impaired blood vessel function, which could lead to high blood pressure, preterm labor and other adverse outcomes, according to the results of a study in rats. The researchers will present their work this week at the American Physiological Society (APS) and American Society for Nephrology Control of Renal Function in Health and Disease conference in Charlottesville, Virginia.

Vitamin D Supplements May Offset Bone Loss Caused by Diabetes Drug

Vitamin D supplementation may help offset damaging bone loss that occurs in some people who take canagliflozin, a commonly prescribed diabetes drug. Researchers will present their work this week at the American Physiological Society (APS) and American Society for Nephrology Control of Renal Function in Health and Disease conference in Charlottesville, Virginia.

AMERICAN SOCIETY OF NEPHROLOGY AND 19 KIDNEY COMMUNITY ORGANIZATIONS CALL ON CONGRESS TO PROTECT LIVING DONORS, FUND RESEARCH AND INNOVATION, AND REMOVE BARRIERS TO TELEHEALTH

Today, advocates of the American Society of Nephrology (ASN) and 19 other kidney health professional and patient organizations are meeting with their congressional delegations, calling on them to enact policies to improve kidney health

Intrauterine Growth Restriction in Rats Causes Long-term Increases in Offspring’s Blood Pressure, Impairs Renal Artery Vascular Tone

Article title: Vascular tone regulation in renal interlobar arteries of male rats is dysfunctional after intrauterine growth restriction Authors: Jenny Voggel, Lubomir Lubomirov, Felix Lechner, Gregor Fink, Eva Nüsken, Maria Wohlfarth, Gabriele Pfitzer, Kija Shah-Hosseini, Martin Hellmich, Miguel A. Alejandre…

Nicotine Damages Kidney Filters in Smokers with Diabetes

Article title: Nicotine, smoking, podocytes and diabetic nephropathy Authors: Edgar A. Jaimes, Ming-Sheng Zhou, Mohammed Siddiqui, Gabriel Rezonzew, Runxia Tian, Surya V. Seshan, Alecia N Muwonge, Nicholas J. Wong, Evren U. Azeloglu, Alessia Fornoni, Sandra Merscher, Leopoldo Raij From the authors:…

Genetics May Determine Who Benefits from Broccoli’s Effects on Kidney Health

• Deletion of the gene that codes for an enzyme called GSTM1 increased kidney injury in mice with hypertension and kidney disease, but supplementing the diet with broccoli powder lessened kidney injury in the genetically altered mice.
• In humans, high consumption of broccoli and other cruciferous vegetables was linked with a lower risk of kidney failure, primarily in individuals lacking GSTM1.

Exploring How a Key Blood Pressure Hormone Works in Males and Females

Aldosterone is a steroid hormone important to the regulation of salt, fluid and potassium in the body. Researchers at the “Metabolic and sex differences in aldosterone responses” symposium will explore the growing body of research that finds sex is a major determinant of how aldosterone acts on the body.

American Physiological Society (APS)

Common Clinical Estimates of Kidney Function May Not Accurately Assess Indian Patients

Pilot study finds that considering body composition rather than weight could improve patient management Charlottesville, Va. (June 25, 2019)—A common metric for monitoring kidney health may not accurately represent the kidney function of Indian patients. However, tweaks to an older…

Baking Soda Boosts Immunity, Impairs Insulin Response in Type 2 Diabetes

Researchers learn insulin response connected to alkaline load, not inflammation Charlottesville, Va. (June 24, 2019)—Early research suggests that the common pantry staple baking soda affects inflammation and insulin handling in type 2 diabetes. The findings will be presented today at…

Blood Metabolite Levels May Help Identify Diabetic Kidney Disease

Noninvasive measurement may provide alternative to diagnostic kidney biopsy Charlottesville, Va. (June 24, 2019)—Metabolomics, the study of small molecules the body produces during metabolism (metabolites) may be a future key to identifying diabetes-related kidney disease. The finding will be presented…

American Physiological Society (APS)

Donald Kohan Details Recent Advances and New Frontiers in Kidney Research in Keynote Address

Charlottesville, Va. (June 23, 2019)—New treatments, exciting research and future trends in kidney health are the focus of discussion at the American Physiological Society (APS)/American Society of Nephrology (ASN) conference, Control of Renal Function in Health and Disease, in Charlottesville,…