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UrduCombining a low dose of blood pressure medication with a higher intake of dietary-resistant starch might help stave off diabetic kidney disease, according to results from a new animal study. Researchers will present their work this week at the American Physiology Summit.
Tag: renal health
Enzyme in T Cells Worsens Salt-sensitive Hypertension and Related Kidney Damage
Article title: Functional NADPH oxidase 2 (NOX2) in T cells amplifies salt-sensitive hypertension and associated renal damage Authors: Samuel D. Walton, John Henry Dasinger, Emily C. Burns, Mary Cherian-Shaw, Justine M. Abais-Battad, David L. Mattson From the authors: “The results…
Researchers Propose New Mouse Model to Study Gene Targeting in Kidney’s Thick Ascending Limb
Article title: A novel mouse model for an inducible gene modification in the renal thick ascending limb Authors: Laurent Bourqui, Denise V. Winter, Alex Odermatt, Dominique Loffing-Cueni, Johannes Loffing From the authors: “This study describes a novel transgenic mouse model…
Researchers Identify Potential New Therapeutic Target for Polycystic Kidney Disease
Article title: The lonidamine derivative H2-gamendazole reduces cyst formation in polycystic kidney disease Authors: Shirin V. Sundar, Julie Xia Zhou, Brenda S. Magenheimer, Gail A. Reif, Darren P. Wallace, Gunda I. Georg, Sudhakar R. Jakkaraj, Joseph S. Tash, Alan S.L.…
Blocking Estrogen in Breast Cancer May Affect Blood Pressure, Kidney Health
Article title: Aromatase inhibition increases blood pressure and markers of renal injury in female rats Authors: Rawan N. Almutlaq, Annie E. Newell-Fugate, Louise C. Evans, Huma Fatima, Eman Y. Gohar From the authors: “The present findings demonstrate that systemic anastrozole…
Flozin Drugs Lower Salt-Induced Hypertension, Maintain Circadian Rhythm in Rats
Article title: SGLT2 inhibition effect on salt-induced hypertension, RAAS and Na+ transport in Dahl SS rats Authors: Olha Kravtsova, Ruslan Bohovyk, Vladislav Levchenko, Oleg Palygin, Christine A. Klemens, Timo Rieg, Alexander Staruschenko From the authors: “The main findings of the…
Past Kidney Disease May Increase Preeclampsia Risk, Impair Blood Vessel Health during Pregnancy
A history of kidney problems may put people at a higher risk for impaired blood vessel function, which could lead to high blood pressure, preterm labor and other adverse outcomes, according to the results of a study in rats. The researchers will present their work this week at the American Physiological Society (APS) and American Society for Nephrology Control of Renal Function in Health and Disease conference in Charlottesville, Virginia.
Mom’s Pregnancy Diet and Low Birth Weight Can Impact Kidney Size at Birth, But Not in Adulthood
Article title: Podocyte endowment and the impact of adult body size on kidney health Authors: Luise A. Cullen-McEwen, James van der Wolde, Kotaro Haruhara, Leon Tribolet, John P. Dowling, Michael G. Bertram, Robert de Matteo, Fabian Haas, Jan Czogalla, Yusuke…
Intrauterine Growth Restriction in Rats Causes Long-term Increases in Offspring’s Blood Pressure, Impairs Renal Artery Vascular Tone
Article title: Vascular tone regulation in renal interlobar arteries of male rats is dysfunctional after intrauterine growth restriction Authors: Jenny Voggel, Lubomir Lubomirov, Felix Lechner, Gregor Fink, Eva Nüsken, Maria Wohlfarth, Gabriele Pfitzer, Kija Shah-Hosseini, Martin Hellmich, Miguel A. Alejandre…
Heparin-based Blood Purification Protects Baboon Kidneys in Severe Pneumonia, Sepsis
Article title: Heparin-based blood purification attenuates organ injury in baboons with S. pneumoniae pneumonia Authors: Lingye Chen, Bryan D. Kraft, Victor L. Roggli, Zachary R. Healy, Christopher W. Woods, Ephraim L. Tsalik, Geoffrey S. Ginsburg, David M. Murdoch, Hagir B.…
Baking Soda Boosts Immunity, Impairs Insulin Response in Type 2 Diabetes
Researchers learn insulin response connected to alkaline load, not inflammation Charlottesville, Va. (June 24, 2019)—Early research suggests that the common pantry staple baking soda affects inflammation and insulin handling in type 2 diabetes. The findings will be presented today at…
Blood Metabolite Levels May Help Identify Diabetic Kidney Disease
Noninvasive measurement may provide alternative to diagnostic kidney biopsy Charlottesville, Va. (June 24, 2019)—Metabolomics, the study of small molecules the body produces during metabolism (metabolites) may be a future key to identifying diabetes-related kidney disease. The finding will be presented…
Donald Kohan Details Recent Advances and New Frontiers in Kidney Research in Keynote Address
Charlottesville, Va. (June 23, 2019)—New treatments, exciting research and future trends in kidney health are the focus of discussion at the American Physiological Society (APS)/American Society of Nephrology (ASN) conference, Control of Renal Function in Health and Disease, in Charlottesville,…