Wearable and Implantable Devices May Transform Care for Patients with Kidney Failure

• Wearable and implantable devices may allow for intensive self-care for patients with kidney failure outside of the clinic.
• Additional research must focus on technological improvements to bring such ambulatory devices to patients as envisioned by the recent Executive Order on the “Advancing American Kidney Health Initiative”.

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Researchers Find New Role for Dopamine in Gene Transcription and Cell Proliferation

A joint group of researchers at the George Washington University and the University of Pittsburgh have found that dopamine and the dopamine D2 receptor modulate expression via the Wnt/β-catenin signaling pathway. This pathway is responsible for control of cell proliferation and organ identity and is implicated in cancer, thus having broad implications for health and development of new therapeutics

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Same Receptor, Different Effect: Research Uncovers New Sex-specific Factor in CV Disease

A common receptor may serve differentiated roles related to aging-associated cardiovascular disease in males and females. Jennifer DuPont, PhD, will present the findings of this first-of-its-kind study today at the American Physiological Society Aldosterone and ENaC Conference in Estes Park, Colo.

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Careful Monitoring of Children Following Cardiac Surgery May Improve Long-Term Outcomes

In a medical records study covering thousands of children, a U.S.-Canadian team led by researchers at Johns Hopkins Medicine concludes that while surgery to correct congenital heart disease (CHD) within 10 years after birth may restore young hearts to healthy function, it also may be associated with an increased risk of death and kidney failure within a few months or years after surgery.

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Simulations Characterize Turbulence Caused by Common Connection for Dialysis

The complex interplay among the arteriovenous grafts, the vessels they connect, and the blood they transport has been difficult to simulate with computers, but one new method provides a way. Researchers report in Physics of Fluids on a series of simulations that reconstructed the fluid dynamics affected by the insertion of an AVG.

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Common Clinical Estimates of Kidney Function May Not Accurately Assess Indian Patients

Pilot study finds that considering body composition rather than weight could improve patient management Charlottesville, Va. (June 25, 2019)—A common

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