Embargoed press materials are now available for the virtual Experimental Biology (EB) 2021 meeting, featuring cutting-edge multidisciplinary research from across the life sciences. EB 2021, to be held April 27–30, is the annual meeting of five scientific societies bringing together thousands of scientists and 25 guest societies in one interdisciplinary community.Read more
The Wake Forest Institute for Regenerative Medicine is investigating how cats with chronic kidney disease could someday help inform treatment for humans.Read more
An artificial intelligence-enabled in vitro diagnostics company and the University of Utah today announced a partnership to improve kidney health and reduce the risk of kidney failure for large scale populations in the earliest stages of kidney disease.Read more
— The American Society of Nephrology (ASN) re- affirms its supporti for the Organ Procurement Organizations (OPOs) Conditions for Coverage final rule issued on November 20, 2020. The society calls for the Biden-Harris administration to implement this final policy as expediently as possible. By bringing objective and verifiable standards to assess the performance of OPOs, this final rule will increase the number of organs available for transplant and reduce racial inequity in the U.S. transplant system.Read more
Researchers have identified factors that make children with diabetic ketoacidosis more likely to experience acute kidney injury. Analyzing data from a large, multicenter clinical trial, the researchers also found that children who experience acute kidney injury are more likely to also experience subtle cognitive impairment and demonstrate lower IQ scores, suggesting a pattern of multiple organ injury.Read more
Removing race from clinical tools that calculate kidney function could have both advantages and disadvantages for Black patients.
Newly diagnosed patients and those whose kidney disease is reclassified as more severe would have greater access to kidney specialists, faster access to the kidney-transplant waitlist.
On the flipside, patients reclassified as having more severe kidney disease may become ineligible for heart, diabetes, pain control and cancer medications or may be given lower doses for these drugs.
A new kidney function score would also increase the number of Black individuals ineligible to donate a kidney, potentially exacerbating organ shortages for Black people.
Researchers caution that clinicians and policy makers must anticipate both the benefits and downsides of changes to the current formula to ensure that Black patients are not disadvantaged, and
health disparities are not exacerbated.
Scientists say the analysis should motivate researchers and clRead more
• Acute kidney injury (AKI) is common during hospitalization with COVID-19 in the U.S. veterans, and it’s associated with a higher risk of death. This risk is especially high for Black veterans.
• Nearly half of the veterans with AKI in this analysis did not fully recover their kidney function by the time of hospital discharge.
Researchers have created an experimental device that, instead of inhibiting inflammatory proteins in COVID-19 patients, changes the phenotype of circulating white blood cells, helping wean two patients off ECMO.Read more
Article title: Distal convoluted tubule sexual dimorphism revealed by advanced 3D imaging Authors: Ebrahim Tahaei, Richard Coleman, Turgay Saritas, DavidRead more
What about the kidneys make them a hotspot for COVID-19’s cytokine storm? A research team says it’s the presence of a protein found on specialized renal transport cells.Read more
Use of drug-coated balloon angioplasty to treat blocked blood vessels used for hemodialysis offers hope for millions of patients globallyRead more
UC San Diego Health is ranked first in San Diego and sixth in California, placing it among the nation’s best hospitals, according to the 2020-2021 U.S. News & World Report. Eight common procedures and conditions were also rated “high performing.”Read more
• A recent study found that most kidney transplant recipients with COVID-19 do not need to be hospitalized.
• Another study found that patients on dialysis who develop COVID-19 may have symptoms that are different from other patients with the infectious disease.
• A new study has found that common terms used by physicians to describe kidney health may be distressing or too difficult to understand for patients with kidney disease.Read more
. Ashita Tolwani, a nephrologist at the University of Alabama at Birmingham, explains how COVID-19 is impacting patients and putting a strain on the availability of dialysis supplies..Read more
• The American Society of Nephrology has launched several initiatives to provide guidance on COVID-19 as it relates to the care of patients with kidney disease.
• Exposure to higher amounts of fine particulate matter air pollution was associated with a higher degree of albuminuria—a marker of kidney dysfunction—as well as a higher risk of developing chronic kidney disease over time.Read more
The February 2020 issue of Toxicological Sciences includes cutting-edge research spanning the toxicological field, from molecular, biochemical, and systems toxicology and nanotoxicology to regulatory science, risk assessment, and decision-making.Read more
High levels of protein in a patient’s urine shortly after an episode of acute kidney injury is associated with increased risk of kidney disease progression, providing a valuable tool in predicting those at highest risk for future loss of kidney function.Read more
• Wearable and implantable devices may allow for intensive self-care for patients with kidney failure outside of the clinic.
• Additional research must focus on technological improvements to bring such ambulatory devices to patients as envisioned by the recent Executive Order on the “Advancing American Kidney Health Initiative”.
A joint group of researchers at the George Washington University and the University of Pittsburgh have found that dopamine and the dopamine D2 receptor modulate expression via the Wnt/β-catenin signaling pathway. This pathway is responsible for control of cell proliferation and organ identity and is implicated in cancer, thus having broad implications for health and development of new therapeuticsRead more
A common receptor may serve differentiated roles related to aging-associated cardiovascular disease in males and females. Jennifer DuPont, PhD, will present the findings of this first-of-its-kind study today at the American Physiological Society Aldosterone and ENaC Conference in Estes Park, Colo.Read more
In a medical records study covering thousands of children, a U.S.-Canadian team led by researchers at Johns Hopkins Medicine concludes that while surgery to correct congenital heart disease (CHD) within 10 years after birth may restore young hearts to healthy function, it also may be associated with an increased risk of death and kidney failure within a few months or years after surgery.Read more
The complex interplay among the arteriovenous grafts, the vessels they connect, and the blood they transport has been difficult to simulate with computers, but one new method provides a way. Researchers report in Physics of Fluids on a series of simulations that reconstructed the fluid dynamics affected by the insertion of an AVG.Read more
Pilot study finds that considering body composition rather than weight could improve patient management Charlottesville, Va. (June 25, 2019)—A commonRead more
Lipopolysaccharide improved outcomes for male, but not female, rats Charlottesville, Va. (June 25, 2019)—In a counterintuitive result, researchers found thatRead more