Synchronisation between the central circadian clock and the circadian clocks of tissues preserves their functioning and prevents ageing

• Two complementary research articles, published simultaneously in the journals Science and Cell Stem Cell by a team of scientists from the UPF and IRB Barcelona, reveal that central and peripheral circadian clocks coordinate to regulate the daily activity of skin and muscles.
• The coordination between the two clocks (central and peripheral) guarantees 50% of the circadian functions of tissues, including vital processes such as the cell cycle, DNA repair, mitochondrial activity, and metabolism.
• Synchronisation between the central brain clock and peripheral ones prevents premature muscle ageing and improves muscle function, suggesting new strategies to tackle age-related decline through circadian rhythm modulation.

JMIR Dermatology Invites Submissions on Diversity in Dermatology

JMIR Publications is pleased to announce a new theme issue titled “Diversity in Dermatology” in JMIR Dermatology. The premier, peer-reviewed journal is indexed in Sherpa Romeo, Scopus, DOAJ, CABI, and PubMed Central/PubMed and is the official journal of the International Society of Digital Health in Dermatology (ISDHD).

Smart protection for delicate skin

Skin injuries caused by prolonged pressure often occur in people who are unable to change their position independently – such as sick newborns in hospitals or elderly people. Thanks to successful partnerships with industry and research, Empa scientists are now launching two smart solutions for pressure sores.

Study Details Toxic Elements Found in Stranded Whales, Dolphins Over 15 Years

Researchers evaluated the prevalence, concentration and tissue distribution of essential and non-essential trace elements, including heavy metal toxicants in tissue (blubber, kidney, liver, skeletal muscle, skin) and fecal samples. Findings reveal how toxicant levels relate to their sex, breed, age and other demographic factors.

Looking sharp! Shark skin is unique and may have medical use, too

Sharks differ from other fish in many ways, including an apparently remarkable ability to heal from wounds, according to reports of sharks recovering from injuries sustained in the wild. While this healing ability has not yet been documented in controlled laboratory conditions, some of the chemical compounds found in shark skin may have significant biomedical potential.

Why does skin get ’leathery’ after too much sun? Bioengineers examine cellular breakdown

A study from Binghamton University, State University of New York researchers explores how ultraviolet radiation can alter the microstructure of human skin. Particularly affected is collagen, the fibrous protein that binds together tissue, tendon, cartilage and bone throughout our bodies.

UC Irvine-led researchers reveal new molecular mechanism for stimulating hair growth

Irvine, Calif., June 21, 2023 — The process by which aged, or senescent, pigment-making cells in the skin cause significant growth of hair inside skin moles, called nevi, has been identified by a research team led by the University of California, Irvine. The discovery may offer a road map for an entirely new generation of molecular therapies for androgenetic alopecia, a common form of hair loss in both women and men.

A New Frontier: Skin Cell Study Looks at Regenerative Medicine in Space

Human skin cells provided by Marjana Tomic-Canic, Ph.D., director of the Wound Healing and Regenerative Medicine Research Program at the University of Miami Miller School of Medicine, were launched to the International Space Station for advanced testing as part of a research voyage by CUTISS, a Swiss life sciences company.

Hybrid Decoders for Marked Point Process Observations and External Influences

Wearable monitoring is likely to play a key role in the future of healthcare. In many cases, wearable devices may monitor our physiological signals that can indicate mental states, such as emotions. The lab of Rose Faghih has been developing a system called MINDWATCH, algorithms and methods for wearable sensors that collect information from electrical signals in the skin to make inferences about mental activity.

Mount Sinai Researchers Identify Mechanisms That Are Essential for Proper Skin Development

Mount Sinai researchers have discovered that Polycomb complexes, groups of proteins that maintain gene expression patterns, are essential for proper skin development, according to a paper published in Genes & Development on February 18.

3D-Printed Smart Gel Changes Shape When Exposed to Light

Inspired by the color-changing skin of cuttlefish, octopuses and squids, Rutgers engineers have created a 3D-printed smart gel that changes shape when exposed to light, becomes “artificial muscle” and may lead to new military camouflage, soft robotics and flexible displays. The engineers also developed a 3D-printed stretchy material that can reveal colors when light changes, according to their study in the journal ACS Applied Materials & Interfaces.

Engineers develop skin rejuvenation method using stem cells

BINGHAMTON, NY — Vesicles derived from human stem cells can be used to rejuvenate skin, according to a research team including faculty at Binghamton University, State University of New York. The use of stem cell-derived extracellular vesicles (EVs) as a cell-free…

High-Tech Printing May Help Eliminate Painful Shots

Painful hypodermic needles may not be needed in the future to give shots, inject drugs and get blood samples. With 4D printing, Rutgers engineers have created tiny needles that mimic parasites that attach to skin and could replace hypodermic needles, according to a study in the journal Advanced Functional Materials.