Technology that can change skin tissue into blood vessels and nerve cells also shows promise as a treatment for traumatic muscle loss.
Immune response and the lymphatic system are central to cardiac repair after a heart attack, according to a study from Ann & Robert H. Lurie Children’s Hospital of Chicago and Northwestern University Feinberg Cardiovascular Research Institute. These insights into the basic mechanisms of cardiac repair are the first step towards developing novel therapeutic approaches to preserve heart function. Findings were published in the Journal of Clinical Investigation.
There are myriad ways in which people can experience physical wounds – from minor scrapes and abrasions to the effects of surgery, critical injuries, burns and other major traumas.
Tracing the impact of a single protein, Piezo1, Penn researchers found that restoring it in muscles affected by Duchenne muscular dystrophy could improve their ability to heal efficiently
Toxicological Sciences delivers the latest toxicology research in the July 2021 issue. The issue features investigations in delivers the latest toxicology research in areas such as exposure to delta-9-tetrahydrocannabinol and cannabidiol, effects of ENDS vapors on amino acid metabolism, and more.
Top researchers in physiology will present a three-part series exploring cellular regulation of mitochondrial function, tissue repair and wound healing. The APS President’s Symposium Series will be part of the APS annual meeting at Experimental Biology 2021, which will be held on a virtual platform April 27–30.
In APL Bioengineering, researchers have developed materials that can interface with an injured spinal cord and provide a scaffolding to facilitate healing. To do this, scaffolding materials need to mimic the natural spinal cord tissue, so they can be readily populated by native cells in the spinal cord, essentially filling in gaps left by injury. The researchers show how the pores improve efficiency of gene therapies administered locally to the injured tissues, which can further promote tissue regeneration.
Article title: CDC-derived extracellular vesicles reprogram inflammatory macrophages to an arginase 1-dependent pro-angiogenic phenotype Authors: Kyle I. Mentkowski, Asma Mursleen, Jonathan D. Snitzer, Lindsey M. Euscher, Jennifer K. Lang From the authors: “Our study was designed to gain mechanistic insight into the…
Bioengineers have created a 3D-printed scaffold designed to regenerate complex tissues composed of multiple layers of cells with different biological and mechanical properties.