in the January 2021 issue, Toxicological Sciences offers an engaging slate of research in toxicology, from endocrine toxicology and biomarkers to genetic and epigenetic toxicology and mixtures toxicology.
An unfortunate truth about using mechanical ventilation to save lives is that the pressure can cause further lung damage. Scientists are working to boost a natural cellular process in pursuit of a therapy that could lower the chances for lung damage in patients on ventilators.
Article title: Sex-specific alterations in blood-borne factors in physically inactive individuals are detrimental to endothelial cell functions Authors: Ryan M. Sapp, Rian Q. Landers-Ramos, Daniel D. Shill, Catherine B. Springer, James M. Hagberg From the authors: “Our data suggest alterations in…
These aspects may have important implications for the design of new drugs and therapeutic interventions for these progressive and incurable diseases.
Researchers have identified a microRNA (miRNA) that could promote hair regeneration. This miRNA – miR-218-5p – plays an important role in regulating the pathway involved in follicle regeneration, and could be a candidate for future drug development.
New research shows that both strands of microRNA cooperate to drive growth and aggressiveness across cancer types, suggesting that these molecules may be more central in deadly cancers than previously thought.