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UrduA prespecified secondary analysis of the MINT (Myocardial Ischemia and Transfusion) trial estimated the effect of 4 strategies to inform an optimal hemoglobin threshold for transfusion among anemic patients suffering from myocardial infarction (MI).
Tag: Myocardial Infarction
SGLT2 Inhibitor Empagliflozin Is Shown to Be Safe and Effective for Treating Patients Who Have Suffered a Heart Attack
The SGLT2 inhibitor empagliflozin confers kidney-protective benefits and can therefore be given safely and effectively to patients when they are hospitalized for acute myocardial infarction (MI), a Mount Sinai-led global team of researchers has shown.
Fewer than 1 in 4 patients receive dietary counseling after a heart attack
Although diet is the leading contributor to premature death from heart disease in the United States, fewer than one-quarter of people who undergo major heart events receive dietary counseling in the aftermath, a study finds. The reason for such a low rate, researchers suggest, may be a lack of time for providing the counseling or expertise in this area by clinicians.
Around 10% of deaths from coronary stenting, balloon angioplasty are preventable
Around 10% of all deaths following percutaneous coronary intervention are potentially preventable, a study led by Michigan Medicine finds.
Advances in the differentiation of pluripotent stem cells into vascular cells
Blood vessels constitute a closed pipe system distributed throughout the body, transporting blood from the heart to other organs and delivering metabolic waste products back to the lungs and kidneys. Changes in blood vessels are related to
Optical Coherence Tomography May Improve Safety and Outcomes for Stenting Procedures in Heart Disease Patients Compared to Conventional Angiography
Results from a large-scale clinical trial results could increase usage of high resolution imaging for guiding interventional coronary procedures
Half as many AF patients dying of heart attacks and strokes in the UK
Patients living with one of the UK’s most common heart rhythm conditions are 50% less likely to die from a heart attack or stroke than they were at the start of the millennium, new research has found.
New discoveries about where atherosclerotic plaques rupture can lead to preventive treatments
A common cause of myocardial infarction and stroke is the rupture of atherosclerotic plaques. The exact location of plaque ruptures has previously been unknown, but now researchers at Lund University have mapped this. The research team has also identified an enzyme, a marker, that they hope will help predict who is at risk of having a myocardial infarction or a stroke due to a ruptured atherosclerotic plaque.
AACN Research Grants Influence Nursing Practice
The American Association of Critical-Care Nurses announces the newest recipients of its annual research grants and invites clinicians and researchers to submit projects online by Oct. 28, 2022, for the next application cycle. AACN will award up to three $50,000 Impact Research Grants in 2023, as well as co-sponsoring the AACN-Sigma Critical Care Grant, with up to $10,000 in funding.
Particle radioactivity linked to pollution-associated heart attack and stroke death
Particle radioactivity, a characteristic of air pollution that reflects the colorless, odorless gas radon found in fine particulate matter (PM2.5) air pollution, enhances PM2.5 toxicity and increases risk of death from cardiovascular disease, especially from heart attack or stroke, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.
Diet change may make biggest impact on reducing heart risk in people with hypertension
Among several lifestyle changes that may reduce cardiovascular disease, adopting the DASH (Dietary Approaches to Stop Hypertension) diet may have the greatest impact for young and middle-aged adults with stage 1 hypertension, according to new research presented at the American Heart Association’s Hypertension Scientific Sessions 2022, held Sept. 7-10, 2022, in San Diego.
Dedicated women’s heart centers can improve accurate diagnoses and outcomes
Cardiac conditions in women are underdiagnosed, undertreated, and under-researched compared to men. In an important prospective study in the Canadian Journal of Cardiology, published by Elsevier, investigators report that attending a multidisciplinary dedicated women’s heart center can increase the likelihood of an accurate diagnosis and significantly improve clinical and psychological outcomes of women reporting chest pain due to insufficient heart-muscle blood flow (myocardial ischemia) but not diagnosed with obstructive coronary artery disease.
Treating, Preventing Heart Attacks with Human Tissue Models
In Biophysics Reviews, researchers explore how human tissue models can be used to examine the impact of heart attacks and treatment of the fibrotic tissue outside the body, improving treatment and diagnosis. They use organoids, 3D organlike multicellular models derived from stem cells, to mimic natural development, structural organization, regeneration, and disease progression. Meanwhile, microfluidic devices control cell placement and fluid flow to act like the heart on a chip, while bioprinting allows cardiac tissue to be built up layer by layer.
“Polypill” Reduces Cardiovascular Mortality by 33 Percent in Patients Treated After a Heart Attack
A three-drug medication known as a “polypill,” developed by the Spanish National Center for Cardiovascular Research (CNIC) and Ferrer, is effective in preventing secondary adverse cardiovascular events in people who have previously had a heart attack, reducing cardiovascular mortality by 33 percent in this patient population.
No association found between mRNA vaccines and severe cardiovascular events
A case-series study has found that adenoviral-based vaccines may be associated with increased risk for myocardial infarction (MI) and pulmonary embolism (PE). No association between mRNA vaccines and severe cardiovascular incidence was found in the short term. Myocarditis and pericarditis were not included in the study. Risk for The findings are published in Annals of Internal Medicine.
Women and Black adults waited longer in ER for chest pain evaluation
Women (ages 18 to 55) waited longer to be evaluated for chest pain in the emergency room (ER) and received a less thorough evaluation for a possible heart attack than men in the same age range.
Mount Sinai Cardiologist Develops New Risk Score to Help Predict Possible Contrast-Associated Kidney Injury After Percutaneous Coronary Intervention
Assessment can help stratify high-risk patients for monitoring before, during, and after procedures to improve outcomes
Bioprinted 3D Cardiac Patches Could Reverse Scar Formation, Promote Myocardial Regeneration After Heart Attacks
Myocardial infarction, or heart attacks, play a large part in heart diseases and the necrosis of cardiac tissue. In APL Bioengineering, researchers take stock of stem cell-laden 3D-bioprinted cardiac patch technologies and their efficacy as a therapeutic and regenerative approach for ischemic cardiomyopathy in reversing scar formation and promoting myocardial regeneration. They explore types of candidate stem cells that possess cardiac regenerative potential and share updates on the challenging implementation of the state-of-the-art 3D-bioprinting approach.
Surprise Discovery Shows Chronic Heart Dysfunction Protects against Acute Kidney Injury
Article title: Activation of hypoxia-sensing pathways promotes renal ischemic preconditioning following myocardial infarction Authors: Andrew S. Terker, Kensuke Sasaki, Juan Pablo Arroyo, Aolei Niu, Suwan Wang, Xiaofeng Fan, Yahua Zhang, Sochinwechi Nwosisi, Ming-Zhi Zhang, Raymond C. Harris From the authors:…
Mount Sinai Cardiologist Awarded $2.9 Million NIH Grant to Advance Work with Stem Cells and Heart Repair after Heart Attack
Research may lead to identifying novel therapies for cardiac patients
Stay Active After Your Heart Attack
Physical activity has been associated with favorable health outcomes including lower risk of chronic diseases and better quality of life. However, knowledge about the benefit of habitual physical activity after people get their first heart attack is limited. In this…
Cutting Down But Not Out: Very-Heavy Drinkers Needn’t Quit Completely for Cardiovascular Benefit
High-risk drinkers who substantially reduce their alcohol use can lower their risk of cardiovascular disease (CVD) despite not completely abstaining, according to study findings published in Alcoholism: Clinical and Experimental Research. CVD encompasses a range of conditions involving the heart or blood vessels, and is the leading cause of death in the US. It is also one of many negative health outcomes associated with heavy drinking and alcohol use disorder (AUD). Reductions in drinking can be defined using World Health Organization (WHO) ‘risk drinking levels’, which classify drinkers into ‘very high’, ‘high’, ‘moderate’ and ‘low’ risk categories based on their average daily alcohol consumption. Previous research has shown that a reduction of two or more levels (for example, from ‘very high’ to ‘moderate’) can lower the risk of multiple health issues, but did not assess the impact on CVD specifically. The latest study has examined associations between reductions in WHO risk drinking
Study Explores Role of Extracellular Vesicles in Tissue Repair after Heart Attack
Article title: CDC-derived extracellular vesicles reprogram inflammatory macrophages to an arginase 1-dependent pro-angiogenic phenotype Authors: Kyle I. Mentkowski, Asma Mursleen, Jonathan D. Snitzer, Lindsey M. Euscher, Jennifer K. Lang From the authors: “Our study was designed to gain mechanistic insight into the…