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UrduMyocardial infarction, or heart attacks, play a large part in heart diseases and the necrosis of cardiac tissue. In APL Bioengineering, researchers take stock of stem cell-laden 3D-bioprinted cardiac patch technologies and their efficacy as a therapeutic and regenerative approach for ischemic cardiomyopathy in reversing scar formation and promoting myocardial regeneration. They explore types of candidate stem cells that possess cardiac regenerative potential and share updates on the challenging implementation of the state-of-the-art 3D-bioprinting approach.
Tag: Myocardial Infarction
Surprise Discovery Shows Chronic Heart Dysfunction Protects against Acute Kidney Injury
Article title: Activation of hypoxia-sensing pathways promotes renal ischemic preconditioning following myocardial infarction Authors: Andrew S. Terker, Kensuke Sasaki, Juan Pablo Arroyo, Aolei Niu, Suwan Wang, Xiaofeng Fan, Yahua Zhang, Sochinwechi Nwosisi, Ming-Zhi Zhang, Raymond C. Harris From the authors:…
Mount Sinai Cardiologist Awarded $2.9 Million NIH Grant to Advance Work with Stem Cells and Heart Repair after Heart Attack
Research may lead to identifying novel therapies for cardiac patients
Stay Active After Your Heart Attack
Physical activity has been associated with favorable health outcomes including lower risk of chronic diseases and better quality of life. However, knowledge about the benefit of habitual physical activity after people get their first heart attack is limited. In this…
Cutting Down But Not Out: Very-Heavy Drinkers Needn’t Quit Completely for Cardiovascular Benefit
High-risk drinkers who substantially reduce their alcohol use can lower their risk of cardiovascular disease (CVD) despite not completely abstaining, according to study findings published in Alcoholism: Clinical and Experimental Research. CVD encompasses a range of conditions involving the heart or blood vessels, and is the leading cause of death in the US. It is also one of many negative health outcomes associated with heavy drinking and alcohol use disorder (AUD). Reductions in drinking can be defined using World Health Organization (WHO) ‘risk drinking levels’, which classify drinkers into ‘very high’, ‘high’, ‘moderate’ and ‘low’ risk categories based on their average daily alcohol consumption. Previous research has shown that a reduction of two or more levels (for example, from ‘very high’ to ‘moderate’) can lower the risk of multiple health issues, but did not assess the impact on CVD specifically. The latest study has examined associations between reductions in WHO risk drinking
Study Explores Role of Extracellular Vesicles in Tissue Repair after Heart Attack
Article title: CDC-derived extracellular vesicles reprogram inflammatory macrophages to an arginase 1-dependent pro-angiogenic phenotype Authors: Kyle I. Mentkowski, Asma Mursleen, Jonathan D. Snitzer, Lindsey M. Euscher, Jennifer K. Lang From the authors: “Our study was designed to gain mechanistic insight into the…