Immune Cell Receptor Provides Promising Immunotherapy Target

Drugs that target a receptor on immune cells called activin receptor 1C may combat tumor-induced immune suppression and help patients’ immune systems fight back against cancer, according to a study by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

BMI OrganBank, Atrium Health and LifeShare Carolinas Partner to Launch Nation’s First Organ Banking Technology

Atrium Health’s Division of Abdominal Transplant, Carolinas Medical Center (DAT Atrium), LifeShare Carolinas, one of nation’s leading Organ Procurement Organizations, and BMI OrganBank, a developer of organ perfusion systems based in Winston-Salem, North Carolina, announced today that their organizations have partnered to develop and launch the nation’s first Organ Banking technology, which will greatly expand the possibilities for organ preservation and reconditioning.

Kidney cancer treatments and tumor biology can activate different immune-modifying processes in patients

The findings out of Dana-Farber Cancer Institute highlight that the mechanisms of immune modulation are different in patients treated with immunotherapy and anti-angiogenic combinations. The results also point to the role of tumor biology in the diversity and actions of tumor-infiltrating immune cells brought into action by these treatments. The findings might be important for predicting or understanding treatment outcomes in advanced kidney cancer.

Doctors discusses recent study about blood pressure and its impacts on heart attacks and strokes

Marc Elieson, MD, at Baylor Scott & White Health, discusses recent study about blood pressure and its impacts on heart attacks and strokes. What You Need to Know: People with high systolic numbers were found more at risk for heart…

Advocating for Equitable Cancer Care: A Call to Establish Comprehensive Survivorship Programming and Enhance Genetic Testing Discussions

Two new measurements have been added to the Health Equity Report Card (HERC)—a tool for improving the quality and equity of cancer care. This expansion is part of ongoing efforts to address the impact of structural and interpersonal racism as a cause of disparities in cancer outcomes in the United States.

ألوان الطيف للبول: ما هو الطبيعي وما هو غير ذلك

أوستن، ولاية مينيسوتا — يتفاوت لون البول الطبيعي ولكنه عادةً ما يتراوح بين الشفاف والأصفر الباهت. ولكن اللون الدقيق يعتمد على كمية المياه التي تشربها، حيث تخفف السوائل من الأصباغ الصفراء في البول. فكلما أكثرت من السوائل، زادت شفافية البول. ولكن عندما تشرب كمية أقل، يصبح اللون الأصفر داكنًا أكثر.

Graphene research: numerous products, no acute dangers

The largest EU research initiative ever launched has come to a successful end: The Graphene Flagship was officially concluded at the end of last year. Empa researchers were also involved, such as molecular biologist Peter Wick, who was part of the Health and Environment work package from the very beginning – and has just summarized the findings in this area with international colleagues in a comprehensive review article in the specialist journal ACS Nano.

Patients Diagnosed With New-Onset, Persistent AFib Are More Likely to Have These Risk Factors

Patients who present with persistent atrial fibrillation at diagnosis are more likely to have certain risk factors as compared with patients with occasional atrial fibrillation (AFib). The findings, led by investigators in the Smidt Heart Institute at Cedars-Sinai, published in Circulation: Arrhythmia and Electrophysiology.

Intravascular Imaging Significantly Improves Survival, Safety, and Outcomes in Cardiovascular Stenting Procedures Over Conventional Angiography

Results from this large-scale synthesis of all prior clinical trials could increase usage of several types of high-resolution imaging for guiding interventional coronary procedures

Long COVID linked to persistently high levels of inflammatory protein: a potential biomarker and target for treatments

SARS-CoV-2 triggers the production of the antiviral protein IFN-γ, which is associated with fatigue, muscle ache and depression. New research shows that in Long COVID patients, IFN-y production persists until symptoms improve, highlighting a potential biomarker and a target for therapies.

Grants Available to Support Initiatives Addressing Nursing Work Environments and Health Equity

AACN, AARP, and the Future of Nursing: Campaign for Action partner to offer the 2024 Health Equity and Nursing Innovations Project Grants: Nursing Workforce and Healthy Work Environments. Awards of up to $25,000 will be given for projects that will be completed in one year. Projects require 1:1 matching funds. Proposals due by April 5.

MD Anderson Research Highlights for February 21, 2024

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. Recent developments at MD Anderson offer insights into drug-drug interactions for patients with acute myeloid leukemia (AML) and myelodysplastic syndromes; patient-derived xenograft models as a viable translational research tool in early-phase clinical trials; a novel gene expression signature to stratify patients with bladder cancer; a potential therapeutic target to overcome treatment resistance in multiple myeloma; a role for mutant p53 in protecting against ferroptosis in triple-negative breast cancer; and diet modifications to improve treatment outcomes in FLT3-mutated AML.

UNC Lineberger named as a national research hub for NIH cancer screening study

UNC Lineberger Comprehensive Cancer Center has been selected as one of nine national research sites for the National Cancer Institute’s newly launched Cancer Screening Research Network, which will evaluate promising and emerging cancer screening technologies.

UAH researcher wins 2024 Worthington Medal for innovations in pumping sciences

Dr. Phillip Ligrani, Eminent Scholar in Propulsion at The University of Alabama in Huntsville (UAH), has won the 2024 American Society of Mechanical Engineers (ASME) Henry R. Worthington Medal for developing innovative micro, millimeter and macro-scale pumping devices. Ligrani’s innovations are beneficial to a variety of applications, such as transporting biological samples without significant alteration or destruction of cells, and supplying coolant to maintain the temperatures of components subject to thermal loading, like lasers.

From segregation to inspiration, James Griffin, M.D., is making history at Parkland and UT Southwestern

To call the connection James D. Griffin, M.D., has with UT Southwestern and Parkland Memorial Hospital lifelong is no exaggeration. Dr. Griffin was born at Parkland in 1958, when the labor and delivery ward was still segregated. More than six decades later, his colleagues at that hospital elected him President of the medical staff – the first Black physician to earn the honor.

Age, sex, race among top risk factors for revision knee surgery

Patients who are younger than about 40, male, or Black are among those most at risk for revision surgery after having had a total knee replacement, according to researchers at UT Southwestern Medical Center. The study, published in the Archives of Orthopaedic and Trauma Surgery, was the first to explore relationships among risk factors for revision after total knee arthroplasty (TKA).

Expert shares advice on the most effective strategies for tax season

Navigating tax season can be a source of stress for many individuals. Virginia Tech finance expert Jesse Lineberry shares ways to stay ahead on tax season to avoid being overwhelmed as the April 15 deadline approaches. Get organized early. “With so many details to account for it’s essential to retrieve all information from previous employers and bankers,” said Lineberry.