In independent research in the American Journal of Physics, Ian Tregillis and George R.R. Martin derive a formula for viral behavior in the Wild Cards, a science fiction series written by a collection of authors about an alien virus called the Wild Card that mutates human DNA. The formula he derived is a Lagrangian formulation, which considers the different ways a system can evolve. It’s also a fundamental physics principle, which also makes the fictional example a powerful teaching tool.
Cracking the code of drug delivery: using computers and AI to make medicine work smarter
Cracking the code of drug delivery: using computers and AI to make medicine work smarter
Researchers at Wake Forest University School of Medicine Receive $3.3 Million Grant from NIH to Study Rare Kidney Disease
Wake Forest University School of Medicine has been awarded a $3.3 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health, to study and develop a treatment for primary hyperoxaluria (PH). This rare genetic disorder causes kidney stones and other serious health problems.
Melanoma metastasis: unveiling the ferroptosis pathway in bone
A recent study has uncovered the molecular mechanisms behind osteocyte death in melanoma bone metastasis, revealing that ferroptosis—an iron-dependent form of cell death—plays a central role in the destruction of bone cells. The research identifies the HIF1α-HMOX1 axis as a critical pathway that induces excessive autophagy and iron overload, leading to osteocyte demise.
Metronomic chemotherapy: a promising approach for pediatric neuroblastoma
Metronomic chemotherapy (MC) is emerging as a groundbreaking treatment for pediatric neuroblastoma, offering a more accessible and manageable option for children with high-risk and relapsed/refractory forms of the disease. This innovative approach could revolutionize care, particularly in low-resource settings where traditional treatments are often out of reach. A recent comprehensive review explores the evolution, clinical applications, and prospects of MC, shedding light on its potential to improve outcomes while reducing toxicity.
Development of a 2-Liter Ammonia-Fueled Engine
The Korea Institute of Machinery and Materials (KIMM), announced that it has developed the world’s first engine capable of directly injecting ammonia into the combustion chamber at high pressure, in collaboration with the Electrification Engineering Center of Hyundai Motor and Kia.
Korea-U.S. Leading Research Institutes Accelerate Collaboration for Energy Technology Innovation
On January 9th (Thu), KIER and the United States Department of Energy’s National Renewable Energy Laboratory signed an MOU for collaboration in renewable energy research and technology development. The partnership aims to expand global collaborations by identifying areas of mutual interest and technology synergies.
The Secret ‘Sex Lives’ of Bacteria: New Research Challenges Old Ideas About How Species Form
New Georgia Tech study shows bacteria form distinct species and maintain cohesion through frequent DNA exchange via homologous recombination.
Sweeping study of human viruses by researchers including UTHealth Houston funded with $20M from NIH
Unlocking knowledge about the vast and varied collection of viruses that live in and on our bodies is the goal of a $20 million grant from the Common Fund of the National Institutes of Health (NIH) to researchers, including a team at UTHealth Houston.
China’s temperature extremes: a 60-year climate chronicle
A recent study sheds light on the spatio-temporal patterns of temperature extremes in China over the past six decades, revealing alarming warming trends and highlighting the critical role of atmospheric circulation factors.
FAU Secures $21M Promise Neighborhoods Grant for Broward UP Underserved Communities
South Florida faces significant challenges, including more than 6,000 homeless children in Broward County and issues like absenteeism, mental health struggles, and limited early learning programs. These factors hinder social mobility and education. To address these issues, FAU received a $21 million grant from the U.S. Department of Education’s Promise Neighborhoods program. The “Broward Unlimited Potential Promise Neighborhood” (Broward UP) initiative aims to provide children with access to quality education and strong community support, ensuring successful transitions to college or careers.
Sentinel skies: tracking wetland health in the clouds
Understanding how alpine wetlands are degrading is crucial for evaluating the full impact of climate change on these fragile ecosystems. In a significant scientific advancement, researchers have introduced alpine wetlands (AW-CCD)—a pioneering algorithm designed to monitor and characterize the complex, multi-scenario degradation of alpine wetlands using Landsat time series data.
A “Quad-Demic” Warning: Symptoms of Viral Influenza, COVID-19, Norovirus, and RSV Can Also Be Signs of Potential Heart Complications
Mount Sinai cardiologists warn about the risk of heart problems during surge of winter viruses for American Heart Month in February
Tiny chip, big breakthrough in spectral sensing for everyday devices
The invention of a microscopic spectral sensor that can identify myriad materials with unprecedented accuracy is set to overhaul our approach to healthcare, food safety and more.
Elaborating On Ethnic Entrepreneurship: How Differences in Immigrant Founders’ Strategic Choices Regarding Human Capital Sourcing Affect Business Model Designs and Evolution
Abstract Strategic human capital literature assumes founders mobilize human resources from the market. Social capital research shows that relying on nonmarket sources, such as ethnic communities, for resources results in distinct ways of organizing business activities in immigrant and nonimmigrant…
FAU’s Randy D. Blakely, Ph.D., Honored as a Prestigious ASPET Fellow
Randy D. Blakely, Ph.D., has been named a Fellow of the American Society for Pharmacology and Experimental Therapeutics (ASPET). Designation as an ASPET Fellow recognizes leaders in the field for their exceptional contributions to pharmacological research, education, mentorship and leadership.
Communicating During Societal Crises: How Entrepreneurs’ Interactions with Backers Affect Fundraising via Crowdfunding
Abstract We investigate how entrepreneurs communicate with crowdfunding backers during the onset of a societal crisis via a content analysis of campaigns active during the COVID-19 pandemic and a vignette experiment. While effective communication with stakeholders is critical for acquiring…
Ryght AI Launches Global Clinical Trial Site Network with the University of Southern California as their First Academic Site
Ryght, a real-time generative AI healthcare technology provider for the clinical research industry, announced today the launch of “The Ryght Research Network”, a global network of clinical research sites. The network includes a growing number of academic institutions, community practices, and healthcare systems of all sizes, across all geographies, covering all therapeutic areas with the intention of providing real-time communications between all trial stakeholders to accelerate clinical trial timelines with AI.
AMERICAN SOCIETY OF NEPHROLOGY COMMENDS SENATE INTRODUCTION OF THE HONOR OUR LIVING DONORS
The American Society of Nephrology (ASN) commends Senator John Boozman and Senator Ben Ray Luján for their introduction of the Honor Our Living Donors (HOLD) Act in the Senate.
Holiday Safety: Johns Hopkins Expert Available
Eileen McDonald, MS, of the Johns Hopkins Bloomberg School of Public Health is available for interviews to discuss holiday safety through a public health lens. She can discuss issues such as Making sure gifts are safe choking risks, sharp edges,…
Most retail choice offers for electricity don’t save consumers money
Ohio’s retail choice electricity market – which lets consumers choose which company provides their electric generation service – has provided residential consumers with mostly cost-increasing offers.
Sylvester Cancer Tip Sheet for Dec. 2024
Coping with grief and holiday sadness; “biological age” as a tool to predict early colorectal cancer, genetic mutations accumulate in smokers with MDS, two clinical trials show promise for an antibody to treat high-risk form of lymphoma, and more.
UC Irvine researchers reveal a revolutionary new approach for 3D CT imaging from a single X-ray projection
Computed tomography (CT) has long been a cornerstone of modern imaging, providing detailed 3D insights into the human body and other materials. However, conventional CT requires hundreds of X-ray projections from multiple angles, exposing patients to significant radiation doses and relying on large, immobile systems.
Insurance challenges limit psychologists’ capacity to address ongoing mental health needs
Although demand for mental health treatment remains high, administrative and financial barriers are preventing many psychologists from participating in insurance networks, according to the American Psychological Association’s 2024 Practitioner Pulse Survey. Barriers by many insurance companies can make it more difficult for psychologists to remain in-network and for patients to access the care they need, exacerbating the ongoing mental health crisis.
$10.8 million grant supports cutting-edge leukemia research
Washington University School of Medicine in St. Louis has received a renewal of a prestigious research grant from the National Cancer Institute. Led by principal investigator, Daniel Link, MD, the Specialized Program of Research Excellence (SPORE) grant in leukemia provides funding for translational research.
Healthy eating habits to carry you through the holidays
This season of office parties and extravagant meals is filled with tempting treats that can make it difficult to reach your health goals. But preserving a well-balanced diet doesn’t mean you have to sacrifice taste or fun, according to nutrition experts at UT Southwestern Medical Center.
Dr. Edward J. Feser Named 34th President of Saint Louis University
Saint Louis University has announced the appointment of Edward J. Feser, Ph.D., as its 34th president.
ما هي تنبؤاتك الصحية؟ خبير يشرح التفسير العلمي وراء التوجيهات الشخصية المتعلقة بالعافية
ربما تكون على دراية بمجموعة من النصائح لعيش حياة صحية مثل مراقبة وزنك وممارسة الرياضة وتناول الأطعمة المغذية والامتناع عن التدخين. ولكن ماذا لو كان بإمكانك الجمع بين عوامل نمط الحياة هذه مع مجموعة من المتغيرات الأخرى لمعرفة خطر التعرض لأمراض بعينها، للمساعدة في اكتشافها وعلاجها مبكرًا أو الوقاية منها بالكلية؟ يشرح فيكتور أورتيجا، دكتور في الطب وحاصل على درجة الدكتوراه، المدير المساعد لمركز مايو كلينك للطب الفردي في ولاية أريزونا، كيف يقترب العلم حثيثًا من جعل مثل هذه التنبؤات الصحية الشخصية ممكنة.
NYU Tandon researchers create microchips capable of detecting and diagnosing diseases
NYU Tandon researchers have developed microchips using field-effect transistors that can detect multiple diseases from a single air sample with high sensitivity. The technology enables rapid testing and could lead to portable diagnostic devices for home and medical use.
Governor Hochul Celebrates the Opening Of New York’s First Cell and Gene Therapy Hub at Roswell Park Comprehensive Cancer Center in Buffalo
Governor Kathy Hochul today celebrated the opening of the Roswell Park GMP Engineering and Cell Manufacturing Facility, New York’s first cell and gene therapy hub, located at Roswell Park Comprehensive Cancer Center in Buffalo. The $98 million facility will create new jobs, help to support the research and development of life-saving cell and gene therapies at Roswell, significantly grow its well-established research capabilities, and establish Roswell as one of the premier cell therapy discovery and development institutions in the nation. The expansion also realizes Governor Hochul’s 2023 State of the State commitment to bolster the state’s leadership in the fast-growing CGT sector through establishment of an Upstate cell and gene therapy hub to catalyze its growth in western NY. The GEM facility meets U.S. FDA Good Manufacturing Practice standards for manufacture of clinical cell therapy products, positioning the Roswell Park team to be a multifaceted resource for patients, care teams
Across southeastern US, weedy rice steals herbicide resistance from crop rice
WashU scientists found that 57% of 201 samples of weedy rice collected from fields in nine counties or parishes of Missouri, Arkansas and Louisiana in 2022 were resistant to the imidazolinone (IMI) family of herbicides.
Threat of abrupt mortality events keeps endangered monkey population at risk, despite decades of growth
Despite the population being almost four times larger than it was in 1982, a new study published in the journal Ecology suggests the northern muriqui monkeys remain at risk, especially in the face of ongoing habitat disturbances.Northern muriquis, which live in the Atlantic Forest of Brazil, are much more peaceful and egalitarian compared to other primates.
Controller with Integrated Machine Learning Tweaks Fusion Plasmas in Real Time
The conditions for high fusion performance in fusion devices can result in damaging energy bursts called edge-localized modes (ELMs). ELMs can be stabilized through small adjustments to the magnetic confinement field, but this approach is usually limited to manual, preprogrammed responses. In this research, scientists integrated machine learning with adaptive control to achieve real-time adjustment capable of responding to the dynamic conditions of a fusion plasma in the DIII-D National Fusion Facility and Korea Institute of Fusion Energy KSTAR tokamaks.
Cornell professor reconstructs ancient canoe using mathematics
Cornell Associate Professor of Mathematics Fabiàn Candelaria used mathematics to study a fragment of a colonial canoe that floated ashore on the west coast of Puerto Rico after sitting underwater for hundreds of years.
Staying sharp: Study explores how brain changes may affect financial skills
A new paper co-written by faculty at Binghamton University, State University of New York sheds light on how age-related changes may affect the way we handle finances — and how we can stay sharp as we age.
DOE’s RENEW Initiative to Support Seven Pathway Summer Institutes for Educators of Underrepresented and Underserved Groups in STEM
The U.S. Department of Energy’s (DOE) Office of Science (SC) will support nearly 85 educators who either teach at schools and community colleges with large populations of students historically underserved and/or underrepresented in STEM or are educators who are from groups traditionally underrepresented in STEM through awards for seven Pathway Summer Institutes for Educators at seven national laboratories.
University Hospitals is the First Health System in Northeast Ohio Utilizing Da Vinci 5 Surgical Robot
University Hospitals is the first health system in Northeast Ohio utilizing the Da Vinci 5 for robotic-assisted surgeries. With substantial improvements over previous models to provide a better experience for surgeons, caregivers and patients, this latest technology represents an evolution in robotic-assisted surgery. Approximately 26 trained surgeons at UH Cleveland Medical Center will be using this robot for a large variety of cases, including esophagectomies and gastric bypasses.
2024 Lawrence Livermore giving campaign raises $3.4 million for nonprofit organizations
Lawrence Livermore National Security (LLNS), LLC, donated more than $3.4 million to nonprofit organizations via the annual employee charitable giving program, the Helping Others More Effectively (HOME) Campaign.
Los Alamos conducts first critical experiment using high assay low enriched uranium in decades
A research team at Los Alamos National Laboratory recently performed the first critical experiment with high assay low enriched uranium (HALEU) TRi-structural ISOtropic (TRISO) fuel in four decades at the National Criticality Experiments Research Center (NCERC) in Nevada. It achieved its objective of establishing an advanced reactor testbed.
UNLV Expert: Regenerating the Brain After a Stroke
UNLV Brain Health researcher Lina Nih is developing a treatment that could one day alter how practitioners address stroke recovery.
Mcity unveils digital twin, making its physical AV testing facility available for free in the virtual world
The first open-source digital twin of the Mcity Test Facility—the University of Michigan’s test center for connected and autonomous vehicles and technologies—is now available to the public, giving researchers around the world a new free tool.
MSU study highlights negative impact of COVID-19 pandemic on special education students in Michigan
Researchers at Michigan State University’s College of Education published a new study exploring learning gaps for students with disabilities and especially for those who are Black, Asian, and economically disadvantaged students — with the 2019-21 school years showing staggering declines in identifying students who could benefit from special education.
Breakthrough in treatment approach showing promise in the fight against glioblastoma, the deadliest and most aggressive type of brain cancer
Mayo Clinic announces the results of an innovative treatment approach that may offer improvement in overall survival in older patients with newly diagnosed glioblastoma while maintaining quality of life. Glioblastoma is the most lethal type of primary brain cancer due to its aggressive nature and its treatment-resistant characteristics. It is the most common form of primary brain cancer.
From advancing X-rays to unlocking exascale: Argonne highlights from 2024
As the year comes to a close, the U.S. Department of Energy’s Argonne National Laboratory reviews some of its most notable achievements of 2024.
Long COVID’s effects on employment: financial distress, fear of judgment
In a new study involving interviews of people with long COVID, researchers describe how the prolonged illness has affected not only patients’ job status, but also their overall well-being.
Consumers of Diet Beverages and Sugar Substitutes Have Lower Quality Diets, New Study Says
A new study shows that people who consume diet beverages and packets of sugar substitutes such as aspartame, sucralose, or stevia have a lower quality diet compared to people who do not eat foods… …
Expert Available: German Chancellor Clears the Way for Snap Election with No Confidence Vote
German Chancellor Olaf Scholz asked the country’s parliament today to declare it has no confidence in him. …
Expert Available on 2024 Holiday Travel: 90% of Holiday Travelers to Hit the Road this Season
AAA is forecasting over 119 million people will be traveling for the holidays, starting Saturday, December 21, 2024 through Wednesday, January 1, 2025. …
Descubrimiento de los pigmentos y las técnicas que se utilizaron para pintar el Muro de Berlín
Los investigadores que publican un artículo en la revista Journal of the American Chemical Society han descubierto información sobre este lugar histórico a partir de fragmentos de pintura usando un detector portátil y el análisis de datos de inteligencia artificial (IA).
Supporting a grieving loved one on holidays and special occasions: Practical tips from a clinical psychologist
The holiday season, often considered a time of joy and togetherness, can also be one of the most challenging periods for those who are grieving a loss.