Opioid Dependence Found to Permanently Change Brains of Rats

Approximately one-quarter of patients who are prescribed opioids for chronic pain misuse them, with five to 10 percent developing an opioid use disorder or addiction. In a new study, UC San Diego researchers found that opioid dependence produced permanent changes in the brains of rats.

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University Hospitals Seidman Cancer Center treats its first glioblastoma patient with genetically modified poliovirus

University Hospitals Seidman Cancer Center treated its first patient in a new clinical trial to validate the groundbreaking effects of the poliovirus on glioblastoma (GBM), a deadly Grade IV cancer of the brain.

UH is the only Midwest site participating in this clinical trial, which was initiated at Duke Cancer Institute in Durham, NC. The original study, which ran from 2012-2017, was published in New England Journal of Medicine in July 2018 as well as highlighted on “60 Minutes” in 2015 and again in 2018. The study found that survival rates were significantly higher in glioblastoma patients who received an intratumoral infusion of a modified viral chimera combining the polio and rhinoviruses (PVSRIPO immunotherapy) compared to patients receiving standard treatment at the same institution.

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Lin Chen receives Award in Experimental Physical Chemistry

The Physical Chemistry Division of the American Chemical Society announces that Lin X. Chen has received the 2020 Award in Experimental Physical Chemistry. The award recognizes Chen for “fundamental contributions to the elucidation of excited state structures, dynamics and energetics of light harvesting systems.

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Advanced Practice Registered Nurses to Have a Greater Role in National Response to Opioid Epidemic

As we enter a new year and a new decade, many states have enacted legislation affecting the roles of advanced practice registered nurses (APRNs) in terms of practice authority, reimbursement, and prescriptive authority, according to the 32nd Annual Legislative Update in the January issue of The Nurse Practitioner, published by Wolters Kluwer.

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Exclusive Polling: Iowa Youth Poised for Historic Caucus Turnout

Young people are poised for a potentially historic turnout in the upcoming Iowa caucuses, and young Democrats prefer Sen. Bernie Sanders, according to an exclusive CIRCLE-Tisch College/Suffolk University Iowa youth poll released today by Tufts University.

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