RUDN pharmacists proposed ways to increase the activity of levofloxacin and overcome bacterial resistance to antimicrobial agents

RUDN University pharmacists modeled derivative molecules of the antibacterial levofloxacin to find out what biological functions its individual structural fragments – pharmacophores – are responsible for. This is necessary to increase the effectiveness of the drug, as bacteria become increasingly resistant to antibiotics.

Preventing tragedy: FSU expert examines suicidal motives in mass shootings, terrorism

By: Amy Walden | Published: February 21, 2024 | 9:21 am | SHARE: According to the Gun Violence Archive, the United States reported 656 mass shootings in 2023. When it comes to understanding and preventing tragedies such as murder-suicides, mass shootings and terrorism, some may question why assailants in these cases are motivated to kill.

Mapping the Future of Rural Revitalization: A New Study Sheds Light on China’s Rural Dynamics

Recent research offers a fresh perspective on the revitalization of rural China through an in-depth analysis of the interconnected development of population, land, and industry in 2020. This study shines a light on the spatial dynamics and underlying factors contributing to rural disparities, providing a critical foundation for crafting scientific, effective, sustainable development strategic plan.

Study Details Toxic Elements Found in Stranded Whales, Dolphins Over 15 Years

Researchers evaluated the prevalence, concentration and tissue distribution of essential and non-essential trace elements, including heavy metal toxicants in tissue (blubber, kidney, liver, skeletal muscle, skin) and fecal samples. Findings reveal how toxicant levels relate to their sex, breed, age and other demographic factors.

Highways through historically redlined areas likely cause air pollution disparities today

Historically “redlined” areas – neighborhoods with primarily Black or immigrant communities – are exposed to more air pollution than other urban neighborhoods. According to research published in ACS’ Environmental Science & Technology, the cause could relate to nearby highways or industrial parks.

Inaccurate pulse oximeter readings could limit transplants, heart pumps for Black patients with heart failure

University of Michigan researchers find that racially biased pulse oximeter readings may further limit opportunities for Black patients with heart failure — who are already less likely to get treatment — to receive potentially lifesaving therapies, such as heart pumps and transplants.

Weedy rice gets competitive boost from its wild neighbors

Weedy rice is an agricultural pest with a global economic impact. It is an aggressive weed that outcompetes cultivated rice and causes billions of dollars in yield losses worldwide. A study from Washington University in St. Louis offers new insights into genetic changes that give weedy rice its edge over cultivated rice in tropical regions of the world.

Membrane Technology: Looking Deep into Smallest Pores

Membranes of vertically aligned carbon nanotubes (VaCNT) can be used to clean or desalinate water at high flow rate and low pressure. Recently, researchers of Karlsruhe Institute of Technology (KIT) and partners carried out steroid hormone adsorption experiments to study the interplay of forces in the small pores. They found that VaCNT of specific pore geometry and pore surface structure are suited for use as highly selective membranes. The researchers report in Nature Communications. (DOI: 10.1038/s41467-024-44883-2)

U of T-led study finds positive support from parents and clinicians for pediatric cancer pain management app

A recent study led by Assistant Professor Lindsay Jibb of the Lawrence Bloomberg Faculty of Nursing and Scientist at The Hospital for Sick Children (SickKids) found that parents of young children with cancer, along with pediatric cancer clinicians are in favour of an app-based solution that Jibb and her team are creating, to help parents manage their child’s cancer pain at home.

Geographic disparities in access to addiction treatment medication may be linked to race, ethnicity

Buprenorphine, a life-saving medication for opioid use disorder, is far less accessible in geographic areas of the United States with racially and ethnically diverse populations than in predominantly white areas, according to a new study of pre-pandemic data led by health policy scientists at the University of Pittsburgh School of Public Health published today in Journal of Addiction Medicine.

Wake Forest University School of Medicine Launches Translational Eye and Vision Research Center

Wake Forest University School of Medicine has launched a new Translational Eye and Vision Research Center, located inside Biotech Place, in Innovation Quarter in Winston-Salem, North Carolina. Leaders envision the center serving as a visionary hub that will redefine the landscape of eye and vision research.

$2 million grant from The Roe Green Foundation catalyzes multidisciplinary research building in Uganda

For the past 38 years, Case Western Reserve University (CWRU) and University Hospitals (UH) have worked closely with a variety of institutions in Uganda to advance medical research and education across a range of fields.

Their facilities have remained scattered across the campuses of local partners but now, the collaboration will have a permanent home.

A $2 million gift from The Roe Green Foundation, jointly awarded to CWRU and UH, will advance global health initiatives from each institution and establish a state-of-the-art research hub and gathering place in Uganda’s capital, Kampala: the Case Western Reserve University and University Hospitals Roe Green Medical Education and Research Building.

Surprising Strategies: Scientists Quantify the Activity of Algal-Associated Bacteria at the Microscale

Microalgae in water are responsible for roughly 50% of the photosynthesis that converts carbon dioxide from the atmosphere into organic carbon. Researchers have now quantified the activity in the microbiome associated with these microalgae to investigate how the microbiome’s members process and exchange carbon and nitrogen from algal cells. They used isotopes and high-resolution imaging mass spectrometry to quantify these exchanges at the single-cell level.

Ochsner Children’s Hospital advocates to close the gap in pediatric heart care

As the only pediatric heart transplant program in Louisiana and the only program in the state to offer advanced mechanical support options for pediatric cardiology patients, Ochsner Children’s Hospital is committed to advocating for additional medical devices to enhance its high-quality care to pediatric patients awaiting transplant.

UWF and DOD SkillBridge program help veteran transition to civilian nursing educator career

After serving in the U.S. Army for 24 years, Lt. Col. Brandy Clayton seamlessly transitioned from military nurse educator to civilian professor through the DOD SkillBridge program, finding her new home at UWF Usha Kundu, MD College of Health School of Nursing.

Water quality monitor, locust-inspired electronic nose under development

Two teams of engineers led by faculty in the McKelvey School of Engineering at Washington University in St. Louis will work toward developing products to monitor drinking water quality and to detect explosives with an electronic nose with one-year, $650,000 Convergence Accelerator Phase 1 grants from the National Science Foundation (NSF).

U.S. Department of Energy Announces $61 Million for Small Business Research and Development Grants

The U.S. Department of Energy (DOE) today announced awards totaling $61 million for small businesses in 17 states. The 50 projects funded by DOE’s Office of Science include the development of advanced scientific instruments, advanced materials, and clean energy conversion and storage technologies that will conduct climate research and advance the Biden-Harris Administration’s goal of a net-zero emissions economy.

Age-Related Changes in Fibroblast Cells Promote Pancreatic Cancer Growth and Spread

Older people may be at greater risk of developing pancreatic cancer and have poorer prognoses because of age-related changes in cells in the pancreas called fibroblasts, according to research led by investigators from the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins Bloomberg School of Public Health and the Bloomberg~Kimmel Institute for Cancer Immunotherapy.