Study provides new understanding of mitochondria genome with potential for new avenues of treatment for multiple cancers

A study led by The University of Texas MD Anderson Cancer Center furthered understanding about mitochondria, the cell components known as the “powerhouse of the cell.” Knowing more about the genome is crucial given that mitochondria play important roles in tumorigenesis.

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Less chemotherapy may have more benefit in rectal cancer

University of Colorado Cancer Center study presented at the 2020 Gastrointestinal Cancers Symposium shows patients with locally advanced rectal cancer receiving lower-than-recommended doses of neoadjuvant chemotherapy in fact saw their tumors shrink more than patients receiving the full dose.

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Researchers identify new therapeutic target for colorectal cancer

Researchers at the University of Toronto have identified a key protein that supports the growth of many colorectal cancers. The study, which will be published December 27 in the Journal of Cell Biology, reveals that a protein called Importin-11 transports the cancer-causing protein βcatenin into the nucleus of colon cancer cells, where it can drive cell proliferation. Inhibiting this transport step could block the growth of most colorectal cancers caused by elevated βcatenin levels.

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Science Snapshots From Berkeley Lab

This edition of Science Snapshots highlights the discovery of an investigational cancer drug that targets tumors caused by mutations in the KRAS gene, the development of a new library of artificial proteins that could accelerate the design of new materials, and new insight into the natural toughening mechanism behind adult tooth enamel.

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Intestinal Stem Cell Genes May Link Dietary Fat and Colon Cancer

Two genes that appear to help stem cells in the intestine burn dietary fat may play a role in colon cancer, according to a Rutgers study. The study, published in the journal Gastroenterology, describes a new connection between the way cells consume fat and how genes regulate stem cell behavior in the intestines of mice.

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New $5.7 Million Grant Aims to Increase Colorectal Cancer Screening, Follow-Up Care in Appalachia

Cancer-control researchers at the University of Kentucky Markey Cancer Center and The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) aim to increase colorectal cancer screening and follow-up care among underserved individuals in Appalachia through a $5.7 million grant from the National Cancer Institute.

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American College of Gastroenterology Announces Winners of Fifth Annual SCOPY Awards

American College of Gastroenterology announces 2019 SCOPY Award winners (Service Award for Colorectal Cancer Outreach, Prevention, and Year-Round Excellence) to recognize the achievements of ACG members in their community engagement, education and awareness efforts for colorectal cancer prevention

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Microbiome Provides New Clues to Determining Development of Colon Cancer

Findings showcasing a connection between bacteria in the microbiome and colon cancer, which may be used to screen younger populations at risk, were published in the journal Gastroenterology by researchers from the George Washington University.

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