Hackensack Meridian Jersey Shore University Medical Center welcomed Lee F. Peng, M.D., PhD, as section chief of gastroenterology, department of medicine.
Tag: Colorectal Cancer
New Research in March: Colorectal Cancer, Kidney Health, OR Supply Costs, and More
The March issue of the Journal of the American College of Surgeons (JACS) features new research on topics ranging from colorectal cancer and social vulnerability to operating room supply costs, the rise in school shootings since 1970, and the impact of permitless open carry laws on suicide rates, among others.
Colorectal cancer ‘not an old people’s disease anymore’
Dr. Issaka’s comments follow the January release of the American Cancer Society’s Cancer statistical report for 2024. Among people under 50 in the U.S., the report said, colorectal cancer is currently the No. 1 cause of cancer death among men and the No. 2 cause of death among women.
Grand Prize Winner: The Southwest Coalition for Colorectal Cancer Screening (SuCCCeS) program
According to the American Cancer Society, the number of colorectal cancers in the US for 2024 are estimated to be about 106,590 new cases of colon cancer (54,210 in men and 52,380 in women) and about 46,220 new cases of rectal cancer (27,330 in men and 18,890 in women).
NCCN Updates Treatment Recommendations for Breast, Colorectal, Lung, and other Cancer Types Based on Emerging Evidence
Recent NCCN Guidelines updates—along with the supporting evidence—will be presented during the NCCN 2024 Annual Conference held in Orlando, Florida April 5-7, and simultaneously online. Visit NCCN.org/conference to learn more and register.
Baylor Scott & White doctor discusses why cancer is impacting more young people
David Winter, MD, at Baylor Scott & White Health, discusses why cancer is impacting more young people. What You Need to Know: People aged 50 and older are living longer because of better cancer detection and treatments. Cancer diagnosis in…
Five Signs of Colorectal Cancer You Shouldn’t Ignore – Even if You’re a Younger Adult
The recent Cancer Facts & Figures 2024 report from American Cancer Society (ACS) researchers revealed a stark increase in colorectal cancer (CRC) incidence among Americans under the age of 55. In just two decades, CRC has moved up from being the fourth leading cause of cancer death in both younger men and women, to first in men and second in women.
VX-509 attenuates the stemness characteristics of colorectal cancer stem-like cells by regulating the epithelial-mesenchymal transition through Nodal/Smad2/3 signaling
BACKGROUNDColorectal cancer stem cells (CCSCs) are heterogeneous cells that can self-renew and undergo multidirectional differentiation in colorectal cancer (CRC) patients. CCSCs are generally accepted to be important sources of CRC and are
Stemming colorectal cancer in Latin America
Little is known about colorectal cancer screening strategies throughout the Western Hemisphere, with the exception of the U.S. and Canada.
Clues to early onset colorectal cancer found in microbiome of Hispanic patients
Nina Sanford, M.D., Chief of Gastrointestinal Radiation Oncology Service, UT Southwestern Medical Center Most people have a screening colonoscropy around age 50, however recent research has uncovered a rise in early onset colorectal cancer in patients younger than 50. What can…
Drug used for cocaine addiction may pave way for new treatment of advanced colon cancer
New research from the University of Ottawa proposes using vanoxerine as a safe method for potentially eliminating cancer stem cells in colorectal tumors.
Case Western Reserve University researcher awarded $2 million federal grant to further explore possible new effective treatments for colorectal and other cancers
With a new $2 million federal grant, a researcher with the Case Western Reserve University School of Medicine will lead a team to further explore preliminary findings of an effective treatment for colorectal and possibly other cancers.
Can personalized care prevent over screening for colorectal cancer in older adults?
Study reveals presenting adults between 76 and 85 with personalized information about the benefits and harms of colon cancer screening decreases excess screening
New Study Shows Insurance Coverage Disruptions Affect Key Cancer Screenings for U.S. Adults
A new study by researchers at the American Cancer Society shows that adults in the United States with prior insurance coverage disruptions are significantly less likely to receive guideline-concordant and past-year cancer screening, compared to people with continuous coverage.
Does diabetes affect the survival of individuals with colorectal cancer?
Study reveals a link between complicated diabetes and a higher risk of death
New gene markers detect Lynch syndrome-associated colorectal cancer, Mayo Clinic study
Researchers from Mayo Clinic Comprehensive Cancer Center and Mayo Clinic Center for Individualized Medicine have discovered new genetic markers to identify Lynch syndrome-associated colorectal cancer with high accuracy.
Exercise boosts anti-cancer immunity and reduces inflammation in Lynch Syndrome patients
Regular and intense aerobic exercise may reduce the risk of colorectal cancer in patients with Lynch Syndrome (LS) by improving the immune system’s ability to detect and remove potentially harmful cells, according to researchers at
The University of Texas MD Anderson Cancer Center.
Only about a quarter of adults overdue for colorectal cancer screening report receiving a clinician recommendation for screening during wellness visit
Most adults overdue for colorectal cancer (CRC) screening report that they did not receive a screening recommendation from their clinician during a wellness visit in the past year, especially among historically marginalized populations.
Colorectal Cancer Patients in Sub-Saharan Africa Receiving Inadequate Care; Survival After Diagnosis Poor, New Study Shows
In new findings led by researchers at the American Cancer Society, Martin-Luther University in Germany, and many other institutes worldwide, fewer than one in 20 patients diagnosed with potentially curable colorectal cancer received standard of care in Sub-Saharan Africa.
Mayo Clinic researchers publish key findings about cell proteins to determine effectiveness of immunotherapy for colon cancer
Mayo Clinic Comprehensive Cancer Center researchers have identified key findings that can assist clinicians in predicting whether a patient with advanced colorectal cancer will benefit from immunotherapy.
NCCN Announces Research Funding for Biomarker-Directed Therapy in Metastatic Colorectal Cancer, in Collaboration with Fight CRC and Pfizer
The National Comprehensive Cancer Network (NCCN) Oncology Research Program (ORP) today announced new grants awarded to improve quality initiatives focused on optimizing biomarker-directed therapy in metastatic colorectal cancer.
New Study in JNCCN Highlights Rapid Adoption of Clinical Research Results into Chemotherapy Prescribing Patterns
JNCCN study sheds light on a rapid shift in practice evolution by oncologists treating people with colon cancer adjuvantly after primary surgery, following publications from the IDEA collaboration.
GI symptoms persist in older female colorectal cancer survivors
More than 4 out of 5 older women survivors of colorectal cancer may be experiencing a range of gastrointestinal symptoms many years after being diagnosed and treated, a new study suggests.
Transcription Factors Contribute to Subtypes of Colorectal Cancers
New research in colorectal cancers directed by investigators at the Johns Hopkins Kimmel Cancer Center suggests that expression of transcription factors — proteins that help turn specific genes on or off by binding to nearby DNA — may play a central role in the degree of DNA methylation across the genome, contributing to the development of different subtypes of these cancers. Methylation is a process in which certain chemical groups attach to areas of DNA that guide genes’ on/off switches.
Alcohol Use, Even at Low Levels, Increases Risk of Developing Disease
Even low levels of alcohol use can increase the likelihood of developing diseases like cancer and heart disease. A systematic review of studies of the relationship between alcohol use and risk of disease published in Alcohol: Clinical and Experimental Research found that disease risk increases as alcohol use increases and high levels of alcohol use have clear detrimental health effects. While lower-level alcohol use can be protective against certain diseases, it can have significant adverse health effects for many other diseases. The authors urge greater awareness that any level of alcohol use can increase a person’s risk of developing serious, even fatal, diseases.
Bowel Research UK chooses Symplectic Grant Tracker to power life-changing research
Bowel Research UK has chosen Symplectic Grant Tracker from Digital Science’s suite of flagship products to advance its aims of funding life-changing research into bowel cancer and other bowel diseases.
Patients with refractory metastatic colorectal cancer experience survival benefits with fruquintinib
Researchers from The University of Texas MD Anderson Cancer Center reported study results showing that the targeted therapy fruquintinib significantly improved overall survival (OS) and progression-free survival (PFS) in patients with refractory metastatic colorectal cancer. Findings from the global FRESCO-2 trial, published today in The Lancet, were first presented at the European Society for Medical Oncology (ESMO) Congress 2022.
Targeted Chemotherapy Helps Cure Some Inoperable Tumors
Physicians at Cedars-Sinai Cancer are using a unique chemotherapy delivery system that offers hope to colorectal cancer patients whose disease has spread and who now have inoperable liver tumors. Cedars-Sinai is one of the few centers in the area to offer the therapy, called hepatic artery infusion (HAI) pump chemotherapy.
Start screenings at age 45 to prevent colorectal cancer, UT Southwestern experts advise
Colorectal cancer is on the rise among younger adults. According to the American Cancer Society, the proportion of cases among people under 55 increased from 11% in 1995 to 20% in 2019, and it is now the leading cause of cancer-related deaths for men younger than 50.
ASCO23: Sylvester Cancer Experts Available for Interviews on a Wide Range of Topics
In addition to presenting Sylvester Comprehensive Cancer Center research findings, Sylvester experts are available at ASCO to share perspectives on a wide variety of topics and studies ranging from breast cancer to sarcoma, prostate cancer, mesothelioma, melanoma, CNS tumors and more.
Study Reveals How Fatty Liver Promotes Colorectal Cancer Spread
Investigators at Cedars-Sinai Cancer found that fatty liver, a condition closely associated with obesity, promotes the spread of colorectal cancer to the liver. Their study, published today in the peer-reviewed journal Cell Metabolism, details the process at the cellular level and could change the way doctors manage the disease in some patients.
Study Explains How “Zombie” Cancer Cells Revive Themselves
One protein brings inactive colorectal cancers back to life, but drugs could block it, Rutgers researchers find.
Financial toxicity of cancer impacts partners’ quality of life
A cancer diagnosis can cause financial strain on patients as they cope with the cost of treatment and lost work. But what about their partners? A new study from University of Michigan Rogel Cancer Center researchers surveyed the partners of colorectal cancer patients and found the financial impact of a loved one’s diagnosis also impacts the partner’s health-related quality of life.
Financial toxicity and quality of life among partners of colorectal cancer survivors
About The Study: This survey study found that partners of colorectal cancer survivors experienced long-term financial toxicity that was associated with worse health-related quality of life. Multilevel interventions for both patients and partners are needed to address factors at individual and…
April Issue of AJG Discusses Colorectal Cancer Risk Factors, H. pylori Infection, and Crohn’s Therapies
The April issue of The American Journal of Gastroenterology highlights new clinical science, including an examination of changes in lifestyle habits and risk of colorectal cancer
Colorectal Cancer Awareness Month
According to the American Cancer Society, colorectal cancer is the third most diagnosed cancer in the United States and the second most common cause of cancer deaths for both men and women. While recent trends show a drop in new…
Prenatal exposure to anti-nausea drug in ‘60s, ‘70s tied to increased risk of colorectal cancer
Prenatal exposure to an anti-nausea drug commonly used in the 1960s and 1970s has been shown to increase risk of colorectal cancer in adult offspring, according to a study by researchers at UTHealth Houston.
Eng invited to White House Cancer Moonshot forum
Cathy Eng, MD, the David H. Johnson Professor of Surgical and Medical Oncology, has been invited to participate in the White House Cancer Moonshot Colorectal Cancer Forum. She will be at the White House Complex on March 10 as administration officials provide updates on progress on several key Moonshot initiatives and seek input from patients, caretakers, oncologists and researchers.
AI improving digestive cancer diagnosis, but data-sharing obstacles remain
Artificial intelligence is helping to deliver earlier and better diagnoses of digestive cancers, but many challenges remain to widespread clinical application, not least limited sharing of medical imaging data between hospitals, and lack of standardization of protocols for medical imaging for AI, a group of researchers has concluded after a comprehensive survey of recent applications of the technology to these most deadly of cancers.
UCLA Health expert available to discuss colorectal cancer screening, the increase in colorectal cancer in young adults, and more during Colorectal Cancer Awareness Month
UCLA Health expert available to discuss colorectal cancer screening, the increase in colorectal cancer in young adults, and more during Colorectal Cancer Awareness Month Folasade May, MD, PhD, UCLA Health colon cancer prevention researcher and gastroenterologist, is available for interview on a variety…
MD Anderson Research Highlights for February 22, 2023
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. Recent developments include a new understanding of how HPV drives cancer development, a combination therapy to overcome treatment resistance in mantle cell lymphoma, novel insights into memory T cell formation and potential therapeutic strategies for brain cancers, improved survival outcomes for metastatic colorectal cancer, targeting myeloperoxidase to improve immunotherapy responses in melanoma, and preclinical results of a combination therapy that could effectively treat a subset of acute myeloid leukemia.
Increased adenoma detection rate may significantly reduce post-colonoscopy colorectal cancer risk in a FIT-based screening program
A cohort study from the Italian Colorectal Cancer screening program including more than 49,000 colonoscopies found a significant inverse association between endoscopists’ proficiency as measured by adenoma detection rate (ADR) and post-colonoscopy colorectal cancer (PCCRC). These finding suggest that targeting only poor performing endoscopists with measures to increase ADR may significantly reduce PCCRC risk. The findings are published in Annals of Internal Medicine.
Immunotherapy with two novel drugs shows activity in colorectal cancer
A combination of two next-generation immunotherapy drugs has shown promising clinical activity in treating patients with refractory metastatic colorectal cancer, a disease which has not previously responded well to immunotherapies, according to a Dana-Farber Cancer Institute researcher.
An Unprecedented Look at Colorectal Cancer
Researchers are building detailed maps of colorectal cancer to better understand the dynamics of the disease
Surgery First for Colon Cancer? Not So Fast, According to New Study in JNCCN
New research in JNCCN finds that immunotherapy from immune checkpoint (PD-1) inhibitors prior to surgery was strikingly effective for patients with localized mismatch repair-deficient or microsatellite instability-high (dMMR/MSI-H) colorectal cancer (CRC).
Large-Scale Study Led by Fred Hutch Finds New Genetic Risk Factors for Colorectal Cancer, Paving the Way for Better Screening, Prevention
A comprehensive analysis of more than 100,000 colorectal cancer (CRC) cases, led by researchers at the Fred Hutchinson Cancer Center in Seattle and 200 scientific collaborators worldwide, has identified more than 100 new genetic risk factors strongly linked with the disease.
Black patients more likely to get emergency colorectal cancer surgery
In an analysis of hospitals across the state of Michigan, University of Michigan researchers found that Black patients were more likely to undergo emergency surgery for colorectal cancer than other races and ethnicities. Emergency surgery was associated with a higher rate of complications, including death.
Protein Alters Expression of Extracellular Vesicle Pathway in Colorectal Cancer, Could Serve as Diagnostic Tool
Article title: IMP1/IGF2BP1 in human colorectal cancer extracellular vesicles Authors: Madeline Kuhn, Yang Zhang, John Favate, Mayu Morita, Aurora Blucher, Sukanya Das, Shun Liang, Ranjan Preet, Louis R. Parham, Kathy N. Williams, Sudheer Molugu, Randall J. Armstrong, Wei Zhang, Jiegang…
MD Anderson Research Highlights: SITC 2022 Special Edition
This special edition features upcoming presentations by MD Anderson researchers at the Society for Immunotherapy of Cancer (SITC) 37th Annual Meeting, including immunotherapy advances in human papillomavirus (HPV)-positive head and neck cancers, microbiome signatures linked with specialized immune-cell clusters, and promising early activity from novel immunotherapy drugs in advanced melanoma and colorectal cancer.
New Study Shows Cancer Mortality Higher Among American Indian and Alaska Native Individuals; Colorectal Cancer Rapidly Increasing Before Age 50
New findings by researchers at the American Cancer Society show overall cancer mortality among American Indian and Alaska Native individuals is 18% higher than among White individuals despite similar cancer incidence. This disparity is driven by common cancers that are receptive to early detection.