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UrduTwo research teams have developed new noninvasive tests that use either blood or saliva samples to diagnose cases of colorectal cancer or prostate cancer, respectively. Presented today at the 2021 AACC Annual Scientific Meeting & Clinical Lab Expo, these tests could facilitate screening efforts for colorectal cancer and allow clinicians to better distinguish early-stage prostate cancer from more benign prostate conditions.
Tag: Colorectal Cancer
New study shows that different types of cancers are likely to spread to specific areas of the brain
Brain metastasis occurs when cancer in one part of the body spreads to the brain. The lifetime incidence of such metastatic brain tumors in cancer patients is between 20%-45%, research shows.
Cleveland Clinic Launches Center for Young-Onset Colorectal Cancer
Cleveland Clinic has established a center focused on the diagnosis, care, and research of young-onset colorectal cancer.
First-of-its-kind study: Use of computer-assisted colonoscopies reduces rate of missed lesions
In the first randomized trial examining the role of a deep-learning based computer-aided detection system during colonoscopy in the U.S., researchers reported a relative reduction of the miss rate by nearly a third when computer-aided detection was used in conjunction with standard-of-care colonoscopy.
Maternal obesity during pregnancy linked to higher risk of colorectal cancer in adult offspring
Infants whose mothers were obese during pregnancy may have a heightened risk of developing colorectal cancer later in life, according to new research led by public health experts at The University of Texas Health Science Center at Houston (UTHealth).
Mechanism for Development of Rare Colorectal Cancer Subtype Identified
Researchers from Rutgers Cancer Institute of New Jersey, the state’s only National Cancer Institute-designated Comprehensive Cancer Center, recently discovered a mechanism to explain what drives the formation of mucinous colorectal adenocarcinoma (MAC), a rare subtype of colorectal cancer.
Fight Colorectal Cancer and Guardant Health Join Forces to Recognize Excellence in Overcoming Challenges to Colorectal Cancer Screening During Pandemic
Selected Recipients of the New “Back to Screening Award for Research Advocacy Excellence” will be Honored at Fight Colorectal Cancer’s “Path to a Cure” Event in December 2021.
Colorectal Cancer Risk May Increase with Lower Exposure to UVB Light
University of California San Diego School of Medicine researchers identified a possible link between inadequate exposure to ultraviolet-B (UVB) light from the sun and an increased risk of colorectal cancer.
Tumor cell PD-L1 may mediate sensitivity to chemotherapy in colorectal cancer treatment
Data in a study by Mayo Clinic Cancer Center researchers indicates that the level of tumor cell PD-L1, a protein that acts as a brake to keep the body’s immune responses under control, may be an important factor for sensitivity to chemotherapy in colorectal cancer treatment. The study was published Friday, July 2, in Oncogene.
New Patient Guide from NCCN Jumpstarts Important Conversations About Anal Cancer
New and updated patient and caregiver resources from National Comprehensive Cancer Network (NCCN) offer jargon-free, state-of-the-art information on diagnosis, treatment, and surveillance for anal, colon, and rectal cancers.
Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine
NEWS STORIES IN THIS ISSUE:
– Study Says Failure to Rid Amyloid Beta Protein from Brain May Lead to Alzheimer’s Disease
– Johns Hopkins Medicine Team Discovers Novel Mediator of Once Mysterious Chronic Itch – Study Suggests Molecular Changes in Tissue Microenvironment May Promote Colorectal Cancer
– Researchers ID Anti-Inflammatory Proteins as Therapy Targets for Nasal and Sinus Problem
– Johns Hopkins Children’s Center Receives NIH Award to Study Dangerous Pediatric Disease
Global Event Will Advance Early Age Onset Colorectal Cancer Research
In many countries around the world, patients under age 50 are fighting, some dying, of colon and rectal cancers. Early-Age Onset Colorectal Cancer is an urgent issue in cancer research and patient care around the globe. We all want to know why this is happening, fully aware that for some, time is running out.
Why Is Lowering The Colorectal Cancer Screening Age to 45 A Big Deal?
Today, the United States Preventive Services Task Force (USPSTF) finalized its recommendation to adapt the colorectal cancer (CRC) screening guidelines and lower the age to begin screening to 45 instead of 50. “Shifting current age-specific screening rates to five years…
Experts available to discuss new USPSTF recommendation to lower age for regular colorectal cancer screenings to 45
Michigan Medicine experts are available to discuss the U.S. Preventive Services Task Force’s new final recommendation that people with no symptoms and an average risk of developing colorectal cancer begin regular colorectal cancer screenings at age 45 instead of 50,…
Mental Health Support: Study Reveals Huge Need Amongst Colorectal Cancer Patients
This Mental Health Awareness Month, Fight Colorectal Cancer, is urging the clinician and patient communities to take mental health seriously and connect patients with resources.
Nanotechnology offers new hope for bowel cancer patients
Bowel cancer is the second deadliest cancer in the world, killing almost 900,000 people in 2020. New research from Indian and Australian scientists suggests that nanotechnology could provide a more effective treatment option than conventional therapy.
Patient reactions to colorectal cancer estimated to become the leading cause of cancer-related deaths for those 20-49 by 2030
In a recent JAMA publication, researchers predict, “For the age group 20-49, colorectal cancer was estimated to become the leading cause of cancer-related deaths by 2030.” Fight Colorectal Cancer (Fight CRC), the nation’s leading advocacy organization, is committed to amplifying…
Mayo study finds colon cancer driven by hereditary gene mutations in 1 in 6 patients
A new Mayo Clinic study bolsters evidence that colorectal cancer is often imprinted in family genes and passed on from one generation to the next.
MD Anderson and TriSalus Life Sciences announce strategic research collaboration to evaluate treatment of solid tumors
MD Anderson and TriSalus announced a strategic research collaboration to evaluate the treatment of liver and pancreas tumors with the investigational therapy SD-101 in combination with immunotherapy using a novel delivery approach.
NYU Langone Seeks to Close the Gap in Colorectal Cancer Disparities with $2.2 Million Cohen Foundation Grant
NYU Langone Health will expand colorectal cancer screenings to address disease disparities in underserved communities with a $2.2 million grant from the Steven & Alexandra Cohen Foundation.
Rock Musicians Rufus Wainwright, Lisa Loeb, Tim Reynolds and More to Perform Free Virtual Concert for Colorectal Cancer Awareness
The American College of Gastroenterology Invites All to “Tune It Up: A Concert To Raise Awareness of Colorectal Cancer” Free Webstream Event Open to All on March 31, 2021 at 8:00 pm EDT
Baby Aspirin Linked to Lower Risk of Colorectal Cancer Death
Long-term, regular use of baby aspirin—at least 15 times per month—prior to a diagnosis of colorectal cancer (CRC) may reduce the risk of death from the disease by limiting the spread of cancerous tumors pre-diagnosis, according to a study led by Cedars-Sinai Cancer researchers.
Drug used during pregnancy may increase cancer risk in mother’s adult children
Exposure in the womb to a drug used to prevent miscarriage appears to raise the offspring’s cancer risk decades later, especially for colorectal and prostate cancers, researchers have found. They will present the results of their new study Tuesday at ENDO 2021, the Endocrine Society’s annual meeting.
GI OnDEMAND Announces Partnership with Ambry Genetics for Genetic Testing and Counseling Services
GI OnDEMAND®, gastroenterology’s leading multidisciplinary virtual integrated care platform today announced a partnership with Ambry Genetics®, a leading clinical genetic testing company, to integrate online genetic counseling and testing services into gastroenterology practices nationwide. This partnership addresses a critical clinical need for identifying hereditary GI cancer syndromes to help guide potentially life-altering health care decisions.
GI OnDEMAND, a joint venture between the American College of Gastroenterology and Gastro Girl, Inc., will now offer the CARE (Comprehensive, Assessment, Risk, and Education) Program™ from Ambry Genetics.
UVA Health’s Dr. Cynthia Yoshida Honored Nationally for Increasing Colorectal Cancer Screenings
UVA Health’s Cynthia M. Yoshida, MD, is one of six winners of a national award recognizing healthcare providers and institutions for their work to increase colorectal cancer screening rates.
American College of Gastroenterology Issues Updated Colorectal Cancer Screening Guidelines
The American College of Gastroenterology has issued updated evidence-based screening guidelines for colorectal cancer (CRC), including a new recommendation to begin CRC screening at age 45 for average risk adults. Key updates include recommendations for screening individuals with family history of CRC or polyps, guidance on the use of aspirin to reduce the risk of CRC, quality indicators for adenoma detection rate and colonoscopy withdrawal time, as well as suggestions about evidence-based interventions to boost screening rates, especially among African Americans. The authors distinguish between one-step screening tests, such as colonoscopy, and two-step screening tests that require colonoscopy, if positive, in order to complete the screening process.
The Medical Minute: Colonoscopy comes calling earlier under new screening guidelines
Evolving evidence shows screening tests should actually start at age 45 for people at average risk for colorectal cancer. Two Penn State Health doctors discuss new guidelines.
Colonoscopy: Yes, This is a Test
Colorectal cancer is the second leading cause of cancer death for both men and women, according to the Centers for Disease Control and Prevention (CDC), even though 90 percent of people who are diagnosed through early testing can be cured.
Putting the Spotlight on Colorectal Cancer Risk and Prevention during Colorectal Cancer Awareness Month
Colorectal Cancer Screening Saves Lives Colorectal cancer is the third most common cause of cancer related death for both men and women. However, if it is caught early, colorectal cancer has a 90% survival rate. This is why screening is…
UCLA expert available to discuss colorectal cancer screening prevention, more during Colorectal Cancer Awareness Month
Folasade May, MD, PhD, UCLA Health colon cancer prevention researcher and gastroenterologist, is available for interview on a variety of topics during colorectal cancer awareness month, including: Why it’s so important to not skip colorectal cancer screenings — even though…
Cancer Cell Vulnerability Points to Potential Treatment Path for Aggressive Disease
New findings, reported in Nature Communications, describe the discovery of a unique dependence of cancer cells on a particular protein, which could lead to desperately needed treatment for hard-to-treat cancers.
Liquid biopsy for colorectal cancer could guide therapy for tumors
A new study from Washington University School of Medicine in St. Louis demonstrates that a liquid biopsy examining blood or urine can help gauge the effectiveness of therapy for colorectal cancer that has just begun to spread beyond the original tumor. Such a biopsy can detect lingering disease and could serve as a guide for deciding whether a patient should undergo further treatments.
MD Anderson and Mirati Therapeutics announce KRAS strategic research and development collaboration in solid tumors
The University of Texas MD Anderson Cancer Center and Mirati Therapeutics, Inc. today announced a strategic research and development collaboration to expand the evaluation of Mirati’s two investigational small molecule, potent and selective KRAS inhibitors – adagrasib (MRTX849), a G12C inhibitor in clinical development, and MRTX1133, a G12D inhibitor in preclinical development, as monotherapy and in combination with other agents – which target two of the most frequent KRAS mutations in cancer.
Take-At-Home Tests Boost Colorectal Cancer Screening Tenfold for Health Center Serving Minorities
By making it the default to send colorectal cancer screening tests to patients’ homes unless they opted out via text message, screening rates increased by more than 1,000 percent
Strange colon discovery explains racial disparities in colorectal cancer
The colons of African-Americans and people of European descent age differently, new research reveals, helping explain racial disparities in colorectal cancer – the cancer that killed beloved “Black Panther” star Chadwick Boseman.
Fight CRC To Present Research Findings on The Impact of COVID-19 on the Colorectal Cancer Community at 2021 GI ASCO
Fight Colorectal Cancer presents abstract at Gastrointestinal Cancer Symposium highlighting the need to address the barriers and opportunities for care within the colorectal cancer community during the COVID-19 pandemic
CDC Awards Huntsman Cancer Institute $3 Million to Increase Colorectal Cancer Screening Rates
Huntsman Cancer Institute at the University of Utah has been awarded a five-year, $3 million grant from the Centers for Disease Control and Prevention to improve Utah’s colorectal cancer screening rates. This funding will provide colorectal cancer screening and follow-up services to people between 50 and 75 years of age through partnership with health systems across Utah.
Fight Colorectal Cancer Issues Four New State Grants to Support Colorectal Cancer Policy Change
The nation’s largest colorectal cancer advocacy organization keeps fighting to lower the screening age and increase access in Kentucky, Nebraska, Rhode Island, and Texas.
Henry Ford Health System is First in the U.S. to Perform Procedure Using CG-100 Device for Colorectal Cancer Patients
Henry Ford Health System is the first in the country to perform a procedure using the CG-100 intraluminal device, which is temporarily inserted into the gastrointestinal tract and designed to reduce diverting stoma rates, and the need for an ostomy bag, in patients undergoing gastrointestinal resection procedures due to colorectal cancer treatment.
Why Black women (and men) are dying of colorectal cancer at higher rates
Dr. Fola P. May is available to discuss the concern over young Black Americans dying of colorectal cancer, such as actor Natalie Desselle-Reid and Chadwick Boseman. “Until we address the lowest screening rates in the most disadvantaged communities in the…
December Issue of The American Journal of Gastroenterology Highlights Health Disparities and Social Determinants of Health
The December issue of The American Journal of Gastroenterology is now available and features new clinical research across a wide range of gastroenterology and hepatology topics, including health disparities, colorectal cancer, cirrhosis, pediatric gastroenterology, the environmental impact of endoscopy, and more.
Multiple Sclerosis May Not Put You at Risk for Breast, Colorectal Cancers
People with multiple sclerosis (MS) may not be at higher risk of developing two of the three cancers that occur most commonly in people with MS, breast and colorectal cancer, than people who don’t have the disease, according to a new study published in the November 25, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology. However, the study did find that people with MS had a higher incidence of bladder cancer.
Surgical Techniques Using Heat May Contribute to Colon Cancer Recurrence in Mice
Article title: Hepatic thermal injury promotes colorectal cancer engraftment in C57/black 6 mice Authors: Alison L. Halpern, J. Gregory Fitz, Yuki Fujiwara, Jeniann Yi, Aimee L. Anderson, Yuwen Zhu, Richard D. Schulick, Karim C. El Kasmi, Carlton C. Barnett Jr.…
Tip Sheet: Holiday tips during a pandemic, new COVID-19 clinical research center opens, colorectal cancer and the microbiome — and advances in ‘suspended animation’
Below are summaries of recent Fred Hutch research findings and other news with links for additional background and media contacts.
American College of Gastroenterology Announces Winners of Sixth Annual SCOPYs: Service Award for Colorectal Cancer Outreach, Prevention, and Year-Round Excellence
The American College of Gastroenterology (ACG) announces the winners of the 2020 SCOPY Awards (Service Award for Colorectal Cancer Outreach, Prevention, and Year-Round Excellence) to recognize the achievements of ACG members in their community engagement, education and awareness efforts for colorectal cancer prevention.
Scientists kill cancer cells by “shutting the door” to the nucleus
Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that blocking the construction of nuclear pores complexes—large channels that control the flow of materials in and out of the cell nucleus—shrank aggressive tumors in mice while leaving healthy cells unharmed. The study, published in Cancer Discovery, a journal of the American Association for Cancer Research, reveals a new Achilles heel for cancer that may lead to better treatments for deadly tumors such as melanoma, leukemia and colorectal cancer.
KRAS inhibitor sotorasib appears safe, achieves durable clinical benefit in early trial
For patients with advanced solid cancers and KRAS G12C mutations, the targeted therapy sotorasib, a KRAS G12C inhibitor, resulted in manageable toxicities and durable clinical benefits, particularly in lung and colorectal cancer, in Phase I study
Daily coffee consumption associated with improved survival in patients with metastatic colorectal cancer
In a large group of patients with metastatic colorectal cancer, consumption of a few cups of coffee a day was associated with longer survival and a lower risk of the cancer worsening, researchers at Dana-Farber Cancer Institute and other organizations report in a new study.
To Reduce Colorectal Cancer Disparities among African American Men, More Intervention Research Is Urgently Needed
African American men have the lowest five-year survival rate for colorectal cancer (CRC) out of any other racial group. A major factor is low adherence to recommended early detection screening. Yet published research on effective strategies to increase screening for this group specifically are minimal. These findings were published today in PLOS ONE.
High-risk Patients for Colorectal Cancer Lack Knowledge About Colonoscopy
Many clinicians rely on self-reports from their high-risk patients about their need and proper interval for repeat surveillance colonoscopy. Researchers analyzed data over four years to explore the knowledge of these high-risk patients. Twenty-eight percent were unaware of either the need for a repeat colonoscopy or the proper surveillance interval. Of these, 16.6 percent were unaware of the proper three-year interval to obtain a follow-up surveillance colonoscopy. Also, 12 percent were not even aware that they required a follow-up surveillance colonoscopy.