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UrduRockville, Md. (April 19, 2024)—Blocking a specific calcium channel called CM4620 may become a new way to treat the life-threatening inflammatory disease acute pancreatitis. While this therapy appears to be the first effective treatment for acute pancreatitis, it has yet…
Tag: Pancreatitis
Exploring the Impact of Pancreatic Enzyme Therapy in Pediatric Pancreatitis: A Leap Toward Personalized Medicine
A research study recently published in the American Journal of Gastroenterology explains the role of pancreatic enzyme therapy (PERT) in reducing the frequency of acute pancreatitis (AP) in children suffering from acute recurrent pancreatitis (ARP) or chronic pancreatitis (CP).
New ACG Guideline on the Management of Acute Pancreatitis and More in the March Issue of AJG
New ACG Clinical Guidelines on the management of acute pancreatitis are featured in the March 2024 issue of AJG
Alcohol Use, Even at Low Levels, Increases Risk of Developing Disease
Even low levels of alcohol use can increase the likelihood of developing diseases like cancer and heart disease. A systematic review of studies of the relationship between alcohol use and risk of disease published in Alcohol: Clinical and Experimental Research found that disease risk increases as alcohol use increases and high levels of alcohol use have clear detrimental health effects. While lower-level alcohol use can be protective against certain diseases, it can have significant adverse health effects for many other diseases. The authors urge greater awareness that any level of alcohol use can increase a person’s risk of developing serious, even fatal, diseases.
Mortality and cost of severe acute pancreatitis keeps pressure on hospitals
Medical experts in Australasia have raised concern about the rising burden of severe acute pancreatitis (SAP) in intensive care units, with no change in mortality rates in these critically ill patients in almost two decades.
In Bid to Make Child Cancer Treatments Safer, Scientists Find Possible Warning Signs of Severe Reaction
Scientists seeking a way to eliminate an adverse reaction to treatments for acute lymphocytic leukemia, a common childhood cancer, have found what they believe to be an early warning indicator. Mouse studies conducted by Rutgers researchers as part of a larger scientific team are pointing to vitamin A levels as a signal that a patient may or may not be vulnerable to a dangerous toxicity.
Vitamin A may reduce pancreatitis risk during ALL treatment
Consuming a diet rich in vitamin A or its analogs may help prevent children and young adults with acute lymphoblastic leukemia (ALL) reduce their risk of developing painful pancreas inflammation during chemotherapy treatment.
A Novel Mechanism May Be Effective in Patients With Severe Hypertriglyceridemia and Prior Episodes of Acute Pancreatitis
A novel type of therapy, known as ANGPTL3 inhibitor therapy, was effective in lowering triglycerides in certain types of patients with severe hypertriglyceridemia (sHTG) who had a prior episode(s) of acute pancreatitis. sHTG is a well-established risk factor for recurrent episodes of acute pancreatitis. These high-risk patients were the focus of a phase 2 study that was led by the Icahn School of Medicine at Mount Sinai and sponsored and funded by Regeneron.
Alcoholic Pancreatitis Patients with Continued Alcohol Intake May Finally Have Therapeutic Options
Researchers at the Miller School are looking for solutions to the continued effects of alcohol use, its harmful impact, and treatment. Understanding the mechanisms of alcohol abuse has gained importance, especially after the COVID-19 pandemic. Higher alcohol consumption led to an increased burden of pancreatic diseases in society.
Link between inflammation and pancreatic cancer development uncovered
A new study in Science finds that pancreatic cells display an adaptive response to repeated inflammation that initially protects against tissue damage but can promote tumor formation in the presence of mutant KRAS.
Researchers Use New Model to Predict Multiorgan Failure in Severe Pancreatitis
Article title: Severe acute pancreatitis: Capillary permeability model linking systemic inflammation to multiorgan failure Authors: Nicole L. Komara, Pedram Paragomi, Phil J. Greer, Anette S. Wilson, Cameron Breze, Georgios I. Papachristou, David C. Whitcomb From the authors: “With the use of…
What you need to know about pancreatitis
Pancreatitis causes more than 360,000 hospitalizations each year. Sajan Nagpal, MD, a medical pancreatologist at the University of Chicago Medicine, answers common questions about this painful condition.