Exercise More, Sit Less to Manage Frailty and Hypertension Risk in Aging

A new study of middle-age and older adults looks at sex differences in frailty levels and their link with heart health. The findings suggest that moving your body more through regular exercise and sitting less can help keep both heart disease and frailty at bay as we age.

An unequal toll of financial stress: Poll of older adults shows different impacts related to health and age

Inflation rates may have cooled off recently, but a new poll shows many older adults are experiencing financial stress – especially those who say they’re in fair or poor physical health or mental health, as well as women and those age 50 to 64. A sizable minority report issues with health care costs.

Drugs that kill “zombie” cells may benefit some older women, but not all, Mayo Clinic study finds

Drugs that selectively kill senescent cells may benefit otherwise healthy older women but are not a “one-size-fits-all” remedy, Mayo Clinic researchers have found. Specifically, these drugs may only benefit people with a high number of senescent cells, according to findings publishing July 2 in Nature Medicine.

Daily Sauna Time Might Help Prevent Menopause-Related Weight Gain

New research performed with mice suggests that daily time in a warm environment such as a sauna might help older adults, especially women, combat age-related obesity and insulin resistance. The study shows the potential of heat treatments as a simple way to promote healthier aging.

Pilot Study Provides ‘Blueprint’ for Evaluating Diet’s Effect on Brain Health

Researchers from Johns Hopkins Medicine and the National Institutes of Health’s National Institute on Aging say their study of 40 older adults with obesity and insulin resistance who were randomly assigned to either an intermittent fasting diet or a standard healthy diet approved by the U.S. Department of Agriculture (USDA) offers important clues about the potential benefits of both eating plans on brain health.

NUTRITION 2024 Press Materials Available Now

Press materials are now available for NUTRITION 2024, the annual flagship meeting of the American Society for Nutrition (ASN). Top nutrition scientists and practitioners from around the world will gather to share the latest research findings on food and nutrition during the meeting in Chicago from June 29–July 2.

Activating molecular target reverses multiple hallmarks of aging

Researchers at The University of Texas MD Anderson Cancer Center have demonstrated that therapeutically restoring ‘youthful’ levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms of aging in preclinical models. If these findings are confirmed in clinical studies, there may be therapeutic implications for age-related diseases such as Alzheimer’s, Parkinson’s, heart disease and cancer.

Hevolution Foundation: Transforming Healthspan Science with Unprecedented $400M Funding Surge

Hevolution Foundation, a global nonprofit organization that provides grants and early-stage investments to incentivize research and entrepreneurship in healthspan science, has committed over $400 million to healthspan sciences within the past 21 months, positioning the Foundation as the world’s largest philanthropic funder of geroscience.

Icahn School of Medicine at Mount Sinai Awarded $21 Million NIH Grant to Advance Understanding of Aging-Related Hormone

Researchers at the Icahn School of Medicine at Mount Sinai have been awarded a $21 million grant from the National Institute on Aging (NIA) of the National Institutes of Health (NIH), to further advance understanding of an aging-related hormone known as follicle-stimulating hormone (FSH), including its potential role in obesity, osteoporosis, and Alzheimer’s disease.

Subtle cognitive decline precedes end to driving for older adults

Even slight cognitive changes can affect an older person’s decision to stop driving, according to a new study by researchers at Washington University School of Medicine in St. Louis. The findings suggest that routine cognitive testing — in particular, the kind of screening designed to pick up the earliest, most subtle decline — could help older adults and their physicians make decisions about driving that maximizes safety while preserving independence as long as possible.

‘Good’ Fat Metabolism Changes Tied to Estrogen Loss, Not Necessarily to Aging

Brown fat metabolism decreases in older men and women, but the decrease in women is not necessarily tied to age, according to new research. The first-of-its-kind study is published ahead of print in the American Journal of Physiology-Endocrinology and Metabolism and has been chosen as an APSselect article for May.

Synchronisation between the central circadian clock and the circadian clocks of tissues preserves their functioning and prevents ageing

• Two complementary research articles, published simultaneously in the journals Science and Cell Stem Cell by a team of scientists from the UPF and IRB Barcelona, reveal that central and peripheral circadian clocks coordinate to regulate the daily activity of skin and muscles.
• The coordination between the two clocks (central and peripheral) guarantees 50% of the circadian functions of tissues, including vital processes such as the cell cycle, DNA repair, mitochondrial activity, and metabolism.
• Synchronisation between the central brain clock and peripheral ones prevents premature muscle ageing and improves muscle function, suggesting new strategies to tackle age-related decline through circadian rhythm modulation.

Early Alzheimer’s Detection with Artificial Intelligence

“AI-driven neuroimaging techniques have the potential to improve prediction models for Alzheimer’s progression and facilitate personalized treatment strategies,” says Domenico Praticò, MD, the Scott Richards North Star Foundation Chair for Alzheimer’s Research, Professor in the Departments of Pharmacology and Microbiology, and Director of the Alzheimer’s Center at Temple (ACT), at the Lewis Katz School of Medicine at Temple University (LKSOM).

Intermittent Fasting May Help Preserve Intestinal Health as We Age

A study in mice found that intermittent fasting brought benefits beyond weight loss, suggesting it could help the body better process glucose and reduce age-related declines in intestinal function. Researchers will present their work this week at the American Physiology Summit.

Study Reveals How Obesity Could Accelerate Aging in the Brain

A new study conducted in mice traces how obesity and a high-fat diet may accelerate aging in the blood vessels that supply blood to the brain. The work is being presented this week at the American Physiology Summit, the flagship annual meeting of the American Physiological Society.

L-Nutra Unveils Groundbreaking Research on Fasting Mimicking Diets (FMDs) and Reduced Biological Age Score

L-Nutra Inc., a leading nutrition technology company developing evidence-based Nutrition for Longevity and Nutrition as Medicine programs, is excited to announce the release of a groundbreaking longevity and healthy aging study published in Nature Communications, a prestigious Nature portfolio journal.

Yoga provides unique cognitive benefits to older women at risk of Alzheimer’s disease, study finds

A new UCLA Health study found Kundalini yoga provided several benefits to cognition and memory for older women at risk of developing Alzheimer’s disease including restoring neural pathways, preventing brain matter decline and reversing aging and inflammation-associated biomarkers – improvements not seen in a group who received standard memory training exercises.

Army of specialized T cells may trigger asthma attacks in older men

LA JOLLA, CA—Scientists from La Jolla Institute for Immunology (LJI) and The University of Southampton, UK, have uncovered a group of immune cells that may drive severe asthma. These cells, called cytotoxic CD4+ tissue-resident memory T cells, gather in the lungs and appear to possess the molecular weaponry to cause the most harm in men who developed asthma later in life.