UChicago researchers recently unveiled a potential new PCOS treatment that restored ovarian function and improved hormonal and metabolic regulation in mice.
Tag: Hormones
Excess Testosterone Can Lead to Increased Cardiovascular Risks in People with Polycystic Ovary Syndrome
Article title: Testosterone-associated blood pressure dysregulation in women with androgen excess polycystic ovary syndrome Authors: Tori Stone, Licy L. Yanes Cardozo, Toni N. Oluwatade, Cheryl A. Leone, Melanie Burgos, Faith Okifo, Lubna Pal, Jane F. Reckelhoff, Nina. S. Stachenfeld From…
Endocrine Society Scientific Statement distinguishes normal aging from endocrine disease
A new Scientific Statement released today by the Endocrine Society highlights the differences between aspects of aging that are normal and sometimes over-treated, and those such as menopausal symptoms and osteoporosis that can be treated and deserve more attention.
ENDO 2023 press conferences to highlight emerging technology and diabetes research
Researchers will delve into the latest research in diabetes, obesity, reproductive health and other aspects of endocrinology during the Endocrine Society’s ENDO 2023 news conferences June 15-18.
Changing Hormone Levels Post-menopause Leads to Vascular Impairment in Female Mice
Article title: Cerebral arteriolar and neurovascular dysfunction after chemically induced menopause in mice Authors: Jade A. Blackwell, Josiane F. Silva, Emma M. Louis, Andrea Savu, Tally M. Largent-Milnes, Heddwen L. Brooks, Paulo W. Pires From the authors: “Together, our data…
“Experienced” Mouse Mothers Tutor Other Females to Parent, Helped by Hormone Oxytocin
The best way to become a good mother just might be learning from an experienced one, if new research on female mice is any indication, according to a Rutgers researcher who filmed thousands of hours of interaction between female mice and found that mouse mothers are outstanding tutors.
New Microchip Sensor Measures Stress Hormones from Drop of Blood
A Rutgers-led team of researchers has developed a microchip that can measure stress hormones in real time from a drop of blood.
New Potential Therapy for Fatty Liver Disease
In a subset of patients with partial lipodystrophy and/or NASH, the hormone leptin can be leveraged as a therapeutic agent to move fat out of the liver.
Exposure to harmful chemicals in plastic may contribute to postpartum depression
Endocrine-disrupting chemicals may influence hormonal shifts during pregnancy as well as contribute to postpartum depression, according to a small study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
Preterm birth, prolonged labor influenced by progesterone balance
New research by the National Institutes of Health found that unbalanced progesterone signals may cause some pregnant women to experience preterm labor or prolonged labor. The study in mice — published online in the Proceedings of the National Academy of Sciences — provides novel insights for developing treatments.

Seasons of Our Hormones
Weizmann Institute scientists analyzed around six million blood tests to obtain data on several types of hormones, discovering that some peak in winter/spring and others in summer. Peaks in stress or reproductive hormones may have “evolved to help us cope with seasonal changes in our surrounding environment.”
Different forms of sugar impact hunger-suppressing hormones in young adults
Drinks with sucrose compared to glucose may cause young adults to produce lower levels of appetite-regulating hormones, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.

HORMONE DIFFERENCES
During birth, hormones in the body surge in both mother and baby, sent along by the nervous system. These stress hormones are there to spur delivery and to help a baby adapt to living outside the womb. A new study finds how one is born can have an effect on the amount of stress hormones released at the time of delivery. For example, vaginal delivery had the highest presence of birth signaling hormones.
Why Do More Women Have Alzheimer’s than Men? It’s Not Just from Living Longer
Middle-aged women are more likely than men to have changes in the brain related to Alzheimer’s disease, as detected by imaging, even when there are no differences in thinking and memory. This may be associated with hormonal changes due to menopause, specifically the loss of estrogen, according to a study published in the June 24, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Researchers Identify Distinct Subtypes of Polycystic Ovary Syndrome With Novel Genetic Associations
Mount Sinai researchers have for the first time identified reproductive and metabolic subtypes of polycystic ovary syndrome (PCOS) that are associated with novel gene regions.
Fish Shed Light on Fatherhood in the Animal Kingdom
Fatherhood looks very different across species. Tiny stickleback fish are especially involved in raising their young, and along with other animals, they’re showing us the impact paternal care can have on both offspring and fathers.

Paying the Price of Protection
A new Weizmann Institute model of autoimmune disease may solve some major outstanding riddles, including what causes T cells to attack and why only certain organs get the diseases
UCLA launches clinical trial to help reduce severity of COVID-19 illness in men
UCLA researchers have launched a new clinical trial that uses a hormone suppresser commonly used to treat men with prostate cancer to help improve clinical outcomes for men infected with COVID-19.

Mother/Infant Skin-to-Skin Touch Boosts Baby’s Brain Development and Function
As the world prioritizes social distancing due to COVID-19, new research shows that extended use of Kangaroo Care, a skin-to-skin, chest-to-chest method of caring for a baby, can positively benefit full-term infants and their mothers, which has important implications for post-partum depression. The study provides evidence that the physiology of mothers and their full-term infants is influenced by Kangaroo care: it increases oxytocin levels in mothers, and during infancy, can favorably influence both neurodevelopmental trajectories and infant neurobiological functioning.
Older Males May Have Weaker Thirst Perception, Higher Dehydration Risk
New research in rats suggests sex hormones and age play a role in dehydration differences in men and women. The study is published in the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology.
Expert Team Tackles Thyroid and Parathyroid Diseases
When the thyroid and parathyroid glands don’t work well, the entire body feels out of balance. To tackle thyroid and parathyroid diseases, Nathan Boyd, MD, recently launched the UNM Thyroid and Parathyroid Surgery Program, housed at the UNM Comprehensive Cancer Center, to offer state-of-the-art treatments for these diseases.

BREAK POINT
At a glance:
Experiments in worms reveal the molecular damage caused by DEHP, a chemical commonly used to make plastics flexible
DEHP interferes with proper cell division during egg formation, leads to excessive DNA breakage, alters chromosome appearance
Abnormalities help explain known link between DEHP and human birth defects, male infertility
If replicated in further research, the insights can help inform regulatory changes, consumer choice
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Mount Sinai Researcher’s Examine the Metabolic Effects of an Oral Blood Cancer Drug
Recent study found that an effective blood cancer treatment was associated with weight gain, obesity, and increased systolic blood pressure