Single hospital study finds transgender teenagers rarely choose to discontinue hormone therapy

A three-year-long retrospective cohort study of a single Atlanta hospital’s patient population found transgender and gender-diverse teenagers rarely chose to discontinue gender-affirming hormone therapy, according to a study being presented Sunday at ENDO 2023, the Endocrine Society’s annual meeting in Chicago, Ill.

Transgender people seen in the ER much more likely than cisgender people to be admitted to hospital

Transgender people who come to the emergency room for care tend to be sicker than cisgender people who are otherwise similar to them and are much more likely to be admitted to the hospital once they visit the ER, according to a study being presented Saturday at ENDO 2023, the Endocrine Society’s annual meeting in Chicago, Ill.

Menopause symptoms: Mayo Clinic expert outlines hormone and nonhormonal therapies

Menopause, the end of menstrual cycles, can produce symptoms such as hot flashes, night sweats, insomnia and mood changes. Women do not need to suffer in silence: Many treatment options are available. Jewel Kling, M.D., chair of the Division of Women’s Health at Mayo Clinic in Scottsdale, Arizona, describes hormonal and nonhormonal therapies.

Hormone therapy could lower risk of immunotherapy-associated myocarditis in women

A new preclinical study from researchers at The University of Texas MD Anderson Cancer Center and the University of California San Francisco (UCSF) has discovered the underlying cause of gender differences in immunotherapy-associated myocarditis after immune checkpoint inhibitor (ICI) treatment. Their findings point to possible treatment strategies for this side effect, which disproportionately affects female patients.

Genetic biomarker test predicts recurrence and survival outcomes for men with high-risk prostate cancer

A new meta-analysis finds that a genetic biomarker test accurately predicts how men with high-risk prostate cancer will respond to treatment with radiation and hormone therapy. The study, which examined biopsy samples collected from three large, randomized clinical trials, indicates that physicians potentially can use genetic test scores to personalize treatment for men with the most aggressive form of prostate cancer. Findings will be presented today at the American Society for Radiation Oncology (ASTRO) Annual Meeting.

Researchers aim to modify fragmented health care system to reduce HIV incidence among trans women

There are an estimated one-million transgender adults living in the U.S. and an estimated 14% of transgender women are living with HIV. Researchers at UTHealth are studying if a combination intervention that combines HIV prevention services and hormonal therapy, supported by peer health navigation, will reduce HIV acquisition among this patient population.

Imaging identifies breast cancer patients unlikely to benefit from hormone therapy

Hormone therapy can be effective for receptor-positive breast cancer, but it only works for 55% of patients. Researchers at Washington University School of Medicine in St. Louis found that only women whose tumors responded to a one-day estrogen challenge benefited from hormone therapy. The findings could help improve treatment decisions.