Vaginal progesterone, a hormone treatment considered the standard of care for preventing preterm birth in at-risk pregnant women, may not be effective, according to UT Southwestern Medical Center researchers.
Kimberly Leslie, MD, was awarded a four-year, $1.8 million grant from the Department of Defense (DOD) to further study high-risk uterine cancer. Her research has led her to study the differences between natural progesterone and synthetic progestins – hormones often used for birth control – and the influence of progesterone on a tumor suppressor protein called p53. The hormones, drugs and proteins, she’s learned, influence each other and the body’s cells in complex ways.
Exposure to harmful chemicals in plastic may contribute to postpartum depression
Endocrine-disrupting chemicals may influence hormonal shifts during pregnancy as well as contribute to postpartum depression, according to a small study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Tuesday.
Study shows protective role sex steroids play in COVID-19
A new paper from a UIC researcher shows evidence that suggests sex steroids may play a role in protecting against COVID-19 symptoms.“Sex and Covid-19: A protective role for reproductive steroids,” by Graziano Pinna, research associate professor in psychiatry, analyzes existing research to look at reasons why COVID-19 symptom severity and mortality are more frequent in men than in women and in older people.
Human pregnancy is weird. A new study adds to the mystery
University at Buffalo and University of Chicago scientists set out to investigate the evolution of a gene that helps women stay pregnant: the progesterone receptor gene. The results come from an analysis of the DNA of 115 mammalian species.
Progesterone from an unexpected source may affect miscarriage risk
Progesterone signaling is key to a healthy pregnancy. An Austrian team’s research suggests a link between recurrent miscarriage and disrupted progesterone synthesis.