A new study in Biotechnology Journal describing a transgenic cow capable of producing human proinsulin and insulin in her milk could have wide-reaching implications for millions of diabetics worldwide. The advancement provides proof-of-concept for a system that would require refinement…
Tag: Diabetes
Positive Results from Diabetic Foot Ulcer Clinical Trial Show Dramatic Healing Rate within 12 Weeks or Less Using Novel Omeza® Platform and Offloading
Omeza®, a regenerative skincare company that develops marine-based therapies for the treatment of chronic wounds, today presented positive interim data from a diabetic foot ulcer (DFU) clinical trial showing that Omeza® OCM™ plus offloading of weight on the affected foot achieved a 91 percent area reduction (PAR) rate in DFUs within twelve weeks, and a 63 percent PAR within four weeks.
Endocrine Society celebrates extension of Special Diabetes Program
The Endocrine Society applauds Congress for approving the first funding increase for the Special Diabetes Program in two decades.
People with Diabetes Who Live in Rural Areas More Likely to Develop Complications of the Disease, UM School of Medicine Study Finds
It has been well established that people who live in rural areas in the U.S. are more likely to have diabetes and experience barriers to managing their condition compared to those who live in the suburbs and cities.
The US Food and Drug Administration issued a warning about the risks of using smartwatches and smart rings that claim to measure blood glucose levels without piercing the skin.
Sabyasachi Sen, a medicine and biochemistry professor at the George Washington University School of Medicine and Health Sciences is available to speak about the warning and what diabetics should rely on to measure their blood sugar for the most accurate…
Hunt School of Dental Medicine Receives $166,000 Grant for Early Diabetes Detection
The screenings program wants to identify patients who are at risk of developing diabetes and connect them with resources that can help them manage their condition. The initiative aligns with the broader goal of integrating diabetes testing into routine screenings across dental clinics in our community.
Advances in the differentiation of pluripotent stem cells into vascular cells
Blood vessels constitute a closed pipe system distributed throughout the body, transporting blood from the heart to other organs and delivering metabolic waste products back to the lungs and kidneys. Changes in blood vessels are related to
New Cedars-Sinai Study Pinpoints Why Some Injured Kidneys Do Not Heal
Cedars-Sinai investigators have discovered why some injured kidneys heal while others develop scarring that can lead to kidney failure. Their findings, detailed in a paper published in the peer-reviewed journal Science, could lead to the development of noninvasive tests to detect kidney scarring and, eventually, new therapies to reverse the condition.
Shifting focus: Investigators describe changes to pancreatic β cell at onset of Type 1 Diabetes
About eight million people live with Type 1 diabetes (T1D) worldwide, a chronic autoimmune condition in which the body attacks and destroys its own insulin-producing β-cells (pronounced “beta”) in the pancreas, leading to a lack of insulin and inability to regulate blood sugar. It’s not known why the body suddenly perceives its own β-cells as the enemy; some lines of evidence suggest environmental factors such as viral infections may trigger the onset of T1D, others suggest genetics may also play some role.
Groundbreaking research by investigators at Joslin Diabetes Center sheds new light on the specific changes β-cells go through at the onset of T1D. Their findings—published in Nature Cell Biology—offer new avenues for targeted interventions for the chronic autoimmune condition.
UT Southwestern study shows glucagon is key for kidney health
Glucagon, a hormone best known for promoting blood sugar production in the liver, also appears to play a key role in maintaining kidney health. When UT Southwestern Medical Center researchers removed receptors for this hormone from mouse kidneys, the animals developed symptoms akin to chronic kidney disease (CKD).
Focus on patient experience can improve diabetes care
Health care providers who treat diabetes need to think beyond the clinical numbers, such as solely focusing on a person’s glucose goals.
Could Ultra-processed Foods Be the New ‘Silent’ Killer?
Hundreds of novel ingredients never encountered by human physiology are now found in nearly 60 percent of the average adult’s diet and nearly 70 percent of children’s diets in the U.S. An emerging health hazard is the unprecedented consumption of these ultra-processed foods in the standard American diet. This may be the new “silent” killer, as was unrecognized high blood pressure in previous decades.
Newly discovered genetic markers help pinpoint diabetes risks, complications
UMass Amherst researcher co-leads worldwide efforts to understand how genetic variants are linked with disease to develop new drugs and treatments.
Giant step forward to help treat chronic wounds that affect millions
A team of international scientists has developed a more effective treatment for chronic wounds that does not involve antibiotics or silver-based dressings, but an ionized gas called plasma.
High out-of-pocket costs hindering treatment of diabetes
Diabetes care providers should account for impacts caused by financial insecurity, researchers suggest
Gastric Bypass Improves Long-Term Diabetes Remission, Even After Weight Recurrence
Adults who have obesity and Type 2 diabetes are much more likely to see their diabetes stay in remission if they undergo gastric bypass surgery rather than sleeve gastrectomy, even after regaining weight, according to a study published in the Journal of the American College of Surgeons (JACS).
Type 2 Diabetes Alters the Behavior of Discs in the Vertebral Column
Type 2 diabetes alters the behavior of discs in the vertebral column, making them stiffer, and also causes the discs to change shape earlier than normal.
Postpartum heart risk: Tips for young moms who may be unaware of long-term dangers
Young women with healthy hearts may be unaware they face elevated risks of developing heart disorders after becoming pregnant. Even worse, the issue may go undetected for years after giving birth because symptoms may mimic those of pregnancy. Dr. Rina…
Males born to obese mothers more likely to suffer health issues as adults
Males born to obese women are more likely to be overweight at birth and develop metabolic complications in later life, including liver disease and diabetes.
Nicolas Musi, MD, Named Inaugural Cypres Chair in Diabetes Research
Nicolas Musi, MD, studies a spectrum of age-related disorders that can impact a healthy lifespan.
UNC Hospitals Performs First Domino Liver Transplant in Decades
Chirag Desai, MD, FACS, an abdominal organ transplant and hepatobiliary-pancreatic surgeon at UNC Hospitals, performed a “domino” liver transplant, which helped two patients from a single donor without splitting a liver.
Weight loss intervention in people with type 2 diabetes influences cancer-associated proteins
A weight loss intervention in people with type 2 diabetes was found to alter levels of cancer-related proteins, according to the findings of a new University of Bristol-led study.
Dexamethasone Implants Could Preserve Vision Longer for Diabetic Macular Edema Patients
Diabetic macular edema (DME) is a significant complication of diabetes, often leading to vision loss. A recent review paper published in the journal MDPI provides evidence-based recommendations on using intravitreal dexamethasone implants (DEX) for treating DME.
Study provides preliminary evidence in favor of a new type 1 diabetes treatment
A new study led by researchers at UChicago Medicine and Indiana University suggests that an existing drug could be repurposed to treat type 1 diabetes, potentially reducing dependence on insulin.
Intermittent fasting is safe, effective for those with Type 2 diabetes
More weight lost among people who fasted, compared to calorie restriction
Research finds potential target for cardiovascular disease in diabetes
Targeting NETs could reduce the risk of heart attack and stroke for diabetic patients
Physician Dispels Myths and Shares Insight Ahead of American Diabetes Month
More than 37 million Americans have been diagnosed with diabetes, with another 8.5 million believed to be living with the condition undiagnosed. In addition, 38 percent of the United States adult population is estimated to have prediabetes, a serious condition…
Does diabetes affect the survival of individuals with colorectal cancer?
Study reveals a link between complicated diabetes and a higher risk of death
High Pregnancy Weight Gain Tied to Higher Risk of Later Death
Findings from 50 years of data highlighted the health risks when more weight is gained in pregnancy than recommended, especially when it comes to heart disease- and diabetes-related mortality
Eye implant may be used to treat diabetes
Researchers in Sweden have developed a microscale device for implantation in the eye, which presents new opportunities for cell-based treatment of diabetes and other diseases
NUS scientists develop innovative magnetic gel that heals diabetic wounds three times faster
A team of researchers from the National University of Singapore has engineered an innovative magnetic wound-healing gel that promises to heal diabetic wounds three times faster, reduce the rates of recurrence, and in turn, lower the incidents of limb amputations.
The innovative magnetic hydrogel, which contains skin cells for healing as well as magnetic particles, takes a comprehensive ‘all-in-one’ approach to wound healing, accelerating the process on several fronts. To maximise therapeutic results, a wireless external magnetic device is used to activate skin cells and accelerate the wound healing process. A patent has been filed for this innovation.
Paro Cardíaco: Hispanos y Latinos con Enfermedad Renal en Alto Riesgo
Los hispanos y latinos con enfermedad renal crónica corren un riesgo significativo de sufrir un paro cardíaco repentino, de acuerdo a un nuevo estudio del Smidt Heart Institute en Cedars-Sinai.
Cardiac Arrest: Hispanics, Latinos With Kidney Disease at High Risk
Hispanics and Latinos with chronic kidney disease are at significant risk for suffering from sudden cardiac arrest, according to a new study from the Smidt Heart Institute at Cedars-Sinai.
Digital Health Tools for Diabetes Management and Virtual Musculoskeletal Care to Undergo Independent Evaluation
The Peterson Health Technology Institute (PHTI) announced today that its initial assessments will focus on remote patient monitoring (RPM) for diabetes management and virtual musculoskeletal care.
Integrated chronic care in Africa can improve outcomes and save money
Across Africa about two million premature deaths each year are caused by the effects of diabetes and hypertension.
Pregnant women offered new hope for safe and effective gestational diabetes treatment
Researchers at University of Galway have taken a significant step forward in the management of gestational diabetes mellitus after a clinical trial involving pregnant women provided new hope for expectant mothers suffering the condition.
Hispanics Are Being Impacted By Diabetes and Kidney Disease
Paula Duran, MD, at Baylor Scott & White Health, answers the most common patient questions and reacts to the latest medical research impacting the Hispanic population. Why do Hispanics have a high incidence of diabetes and subsequent kidney disease? Is…
Type 2 diabetes diagnosis at age 30 can reduce life expectancy by up to 14 years
An individual diagnosed with type 2 diabetes at age 30 years could see their life expectancy fall by as much as 14 years, an international team of researchers has warned.
Van Andel Institute scientist awarded $2.9 million to tackle insulin resistance, a driver of Type 2 diabetes
Nick Burton, Ph.D., has earned a five-year, nearly $2.9 million New Innovator Award from the National Institutes of Health Common Fund to find new ways to fix or prevent insulin resistance, a key driver of Type 2 diabetes.
UCI launches innovative initiative to address diabetes in the Latinx community
Orange, Calif. — The University of California, Irvine has launched an initiative to address the toll diabetes takes on Orange County’s Latinx community and ensure greater well-being for a population that is disproportionately affected by the disease.
Pharmacist-led intervention can improve medication adherence among Latinos with type 2 diabetes
Diabetes control can significantly improve for Latinos when a pharmacist implements an intervention that addresses these patients’ barriers to medication adherence.
Wearable devices show who may need more help managing diabetes
A new Dartmouth study in the journal Science Advances suggests that how well people with diabetes manage their blood sugar depends on their experience with the condition and their overall success in controlling their glucose levels, as well as on the season and time of day.
Almost 4 in 10 adults with type 1 diabetes are not diagnosed until after age 30
A brief research report including more than 900 adults with type 1 diabetes found that 37 percent, or nearly 4 in 10 participants, were diagnosed with type 1 diabetes after age 30. Age of diagnosis was higher for men and racial minority adults. The findings are published in Annals of Internal Medicine.
Once-weekly insulin icodec with dosing guide app showed superior HbA1c reduction versus once-daily insulin in phase 3a trial
In the Phase 3a ONWARDS 5 randomized trial, once-weekly insulin icodec titrated with a dosing guide app demonstrated superior reduction in HbA1c levels and similarly low hypoglycemia rates compared with once-daily insulin. The findings are published in Annals of Internal Medicine.
Exercise-mimicking drug sheds weight, boosts muscle activity in mice
A new drug encourages weight loss and increases endurance by making the body act like it is exercising.
An implantable device could enable injection-free control of diabetes
One promising approach to treating Type 1 diabetes is implanting pancreatic islet cells that can produce insulin when needed, which can free patients from giving themselves frequent insulin injections.
Self-reported “night owls” more likely to have unhealthy lifestyle behaviors, significantly increased diabetes risk
A study of more than 60,000 middle-aged nurses found that people with an evening chronotype, or a circadian preference to feel energetic later in the day, experienced an increased risk for diabetes and were more likely to report unhealthy lifestyle behaviors, such as smoking, poor sleep and physical inactivity, compared with persons with a morning chronotype.
COVID-19 and Type 1 Diabetes: Researchers Find an Increase in Islet Autoimmunity in Young Children Who Had a Sars-CoV-2 Infection
Type 1 diabetes is an autoimmune disease leading to an impaired glucose metabolism and requires life-long administration of insulin. While the cause of the autoimmunity reaction is still unclear, viral infections in young children are proposed to be critical environmental factors leading to type 1 diabetes.
MEDIA ADVISORY: Cedars-Sinai Experts Available to Discuss Safety, Benefits of Using Medications to Lose Weight
The science is unclear on exactly why an increasingly popular new class of federally approved diabetes and obesity medications work, but they do know that they are effective at helping people lose weight.
Endocrine Society honors endocrinology field’s leaders with 2024 Laureate Awards
The Endocrine Society today announced it has chosen 14 leading endocrinologists as winners of its prestigious 2024 Laureate Awards, the top honors in the field.