Reports on variants of the coronavirus that causes COVID-19 have swept the news over the past few months, but what exactly is a virus variant?
In a new perspective piece published in the Feb. 5 issue of Science, pharmacologist Namandje Bumpus, Ph.D. — who recently became the first African American woman to head a Johns Hopkins University School of Medicine department, and is the only African American woman leading a pharmacology department in the country — outlines the molecular origins for differences in how well certain drugs work among distinct populations. She also lays out a four-part plan to improve the equity of drug development.
We use recycled products every day. Money, for example, goes on a circular journey from our hands to banks and back again. Once paper money is too worn to be used, banks send it to be destroyed. A similar microscopic waste system is present in our brains, in which nervous system cells called neurons trade chemical messengers and remove the carriers they travel in when they become defective.
Age may cause identical cancer cells with the same mutations to behave differently. In animal and laboratory models of melanoma cells, age was a primary factor in treatment response.
Johns Hopkins Medicine researchers report that new experiments with genetically engineered mice have found clear connections among a range of autism types and abnormalities in brain cells whose chemical output forges platonic (non-sexual) feelings of love and sociability.
Johns Hopkins Medicine has launched a new Spanish-language COVID-19 resources portal. This one-stop shop for information in Spanish offers COVID-19 testing sites, information about telemedicine and communicating with health care providers, social distancing tips and resources for children, among other helpful links. The mobile-friendly portal serves community members, patients, faculty and staff members as well as students who need COVID-19 resources and information in Spanish.
SEATTLE – Oct. 1, 2020 – Below are summaries of recent Fred Hutch research findings and other news with links for additional background and media contacts.And if you’re looking for sources for October’s Breast Cancer Awareness Month, please see our breast cancer page for a list of projects, experts and the latest breast cancer news.
During the lockdown with COVID-19 restrictions in place, an interactive gaming room built to accelerate stroke patient recovery in The Johns Hopkins Hospital wasn’t getting much use. The therapists and neurologists running the gaming room decided to make the room available to staff treating COVID-19 patients to allow them to decompress.
Scientists at Johns Hopkins Medicine and the University of Oxford say they have found a new way to kill some multiplying human breast cancer cells by selectively attacking the core of their cell division machinery. The technique, so far tested only on lab-grown and patient-derived cancer cells, could advance efforts to find drugs that kill breast cancer cells in a subset of patients, and leave healthy cells unharmed.
Researchers have long sought to explain precisely how the most common genetic mutation linked to both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia causes the death of nerve cells.
Johns Hopkins Medicine researchers have added to evidence that a gene responsible for turning off a cell’s natural “suicide” signals may also be the culprit in making breast cancer and melanoma cells resistant to therapies that use the immune system to fight cancer. A summary of the research, conducted with mice and human cells, appeared Aug. 25 in Cell Reports.
In laboratory studies, Johns Hopkins Kimmel Cancer Center and Johns Hopkins University researchers observed a key step in how cancer cells may spread from a primary tumor to a distant site within the body, a process known as metastasis.
Scientists at Johns Hopkins Medicine using MRI scans and computer modeling say they have further pinpointed areas of the human brain that regulate efforts to deal with fatigue.
The findings, they say, could advance the development of behavioral and other strategies that increase physical performance in healthy people, and also illuminate the neural mechanisms that contribute to fatigue in people with depression, multiple sclerosis and stroke.
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every Tuesday throughout the duration of the outbreak.