Spinal Cord Injury

Injectable Porous Scaffolds Promote Better, Quicker Healing After Spinal Cord Injuries

In APL Bioengineering, researchers have developed materials that can interface with an injured spinal cord and provide a scaffolding to facilitate healing. To do this, scaffolding materials need to mimic the natural spinal cord tissue, so they can be readily populated by native cells in the spinal cord, essentially filling in gaps left by injury. The researchers show how the pores improve efficiency of gene therapies administered locally to the injured tissues, which can further promote tissue regeneration.

Scientists show MRI predicts the efficacy of a stem cell therapy for brain injury

Scientists at Sanford Burnham Prebys Medical Discovery Institute and Loma Linda University Health have demonstrated the promise of applying magnetic resonance imaging (MRI) to predict the efficacy of using human neural stem cells to treat a brain injury—a first-ever “biomarker” for regenerative medicine that could help personalize stem cell treatments for neurological disorders and improve efficacy. The study was published in Cell Reports.

Synapse Biomedical receives FDA emergency approval to use temporary breathing pacing device for COVID-19

Synapse Biomedical, a spin out company from University Hospitals Cleveland Medical Center (UH) and Case Western Reserve University (CWRU), has received FDA approval for emergency use of its TransAeris Diaphragmatic Pacing Stimulator System to help wean any patient off of the ventilator including COVID-19 patients. Diaphragm pacing has the potential of freeing up ventilators as patients could be moved off of ventilators and placed on the pacing system.