In APL Bioengineering, researchers have developed materials that can interface with an injured spinal cord and provide a scaffolding to facilitate healing. To do this, scaffolding materials need to mimic the natural spinal cord tissue, so they can be readily populated by native cells in the spinal cord, essentially filling in gaps left by injury. The researchers show how the pores improve efficiency of gene therapies administered locally to the injured tissues, which can further promote tissue regeneration.
University of Washington researchers helped six Seattle-area people with spinal cord injuries regain some hand and arm mobility.
Thanks to advances in health care in the past several decades, more than 90% of…
How Does Intermittent Hypoxia Amplify the Functional Benefits of Task-specific Rehabilitation after Spinal Cord Injury?
Spinal cord injury impairs motor function, leading to chronic disability. Traditional exercise-based (task-specific) training alone…
Researchers at UC San Diego School of Medicine report successfully implanting specialized grafts of neural stem cells directly into spinal cord injuries in mice, then documenting how the grafts grew and filled the injury sites, mimicking the animals’ existing neuronal network.
Researchers at The Ohio State University Wexner Medical Center and College of Medicine found that spinal cord injuries in mice cause an acquired bone marrow failure syndrome that may contribute to chronic immune dysfunction.
Research from the Department of Kinesiology at McMaster University has found that the practical advantages of high-intensity interval training (HIIT), or short bursts of all-out exercise, could be especially beneficial for people who have experienced spinal cord injuries (SCI).
Scientists at Sanford Burnham Prebys Medical Discovery Institute and Loma Linda University Health have demonstrated the promise of applying magnetic resonance imaging (MRI) to predict the efficacy of using human neural stem cells to treat a brain injury—a first-ever “biomarker” for regenerative medicine that could help personalize stem cell treatments for neurological disorders and improve efficacy. The study was published in Cell Reports.
Article title: Recovery of locomotion in cats after severe contusion of the low thoracic spinal cord…
A new study finds adults with traumatic spinal cord injury are at an increased risk of developing mental health disorders and secondary chronic diseases compared to adults without the condition.
When adult brain cells are injured, they revert to an embryonic state, say researchers at UC San Diego School of Medicine. In their newly adopted immature state, the cells become capable of re-growing new connections that, under the right conditions, can help to restore lost function.
Synapse Biomedical receives FDA emergency approval to use temporary breathing pacing device for COVID-19
Synapse Biomedical, a spin out company from University Hospitals Cleveland Medical Center (UH) and Case Western Reserve University (CWRU), has received FDA approval for emergency use of its TransAeris Diaphragmatic Pacing Stimulator System to help wean any patient off of the ventilator including COVID-19 patients. Diaphragm pacing has the potential of freeing up ventilators as patients could be moved off of ventilators and placed on the pacing system.
Researchers at UC San Diego School of Medicine, with colleagues, describe a new method for delivering neural precursor cells to spinal cord injuries in rats, reducing the risk of further injury and boosting the propagation of potentially reparative cells.
A molecular switch has the ability to turn on a substance in animals that repairs neurological damage in disorders such as multiple sclerosis (MS), Mayo Clinic researchers discovered.
Long-term treatment with gabapentin, a commonly prescribed drug for nerve pain, could help restore upper limb function after a spinal cord injury, new research in mice suggests.
Stem cells derived from a patient’s own fat offer a step toward improving — not just stabilizing — motor and sensory function of people with spinal cord injuries, according to early research from Mayo Clinic.