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UrduEarlier menopause combined with higher risk of cardiovascular disease is linked to an increased risk of thinking and memory problems later, according to a new study published in the April 3, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology. In this study, earlier menopause is defined as occurring before age 49.
Tag: Alzheimer’s disease
Do Veterans Who Experience Concussions Have an Increased Risk of Alzheimer’s?
Middle-age veterans who experienced concussions due to blasts from explosive devices may have biomarkers in their spinal fluid similar to people who develop Alzheimer’s disease, according to a new study published in the March 13, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Researchers make precious headway into a genetic form of Alzheimer’s disease
UC Santa Barbara researchers and collaborators in Colombia, Brazil and Germany are progressing toward an understanding of mechanisms that underlie Alzheimer’s disease, in particular an early-onset, genetic form that has afflicted generations of an extended family in Colombia.
New genetic therapy holds promise for ALS and frontotemporal dementia
Neuroscientists at Macquarie University in Australia have developed a single-dose genetic medicine that has been proven to halt the progression of both ALS and frontotemporal dementia (FTD) in mice – and may even offer the potential to reverse some of the effects of the fatal diseases.
Erectile Dysfunction Drugs May Be Linked to Reduced Risk of Alzheimer’s Disease
The drugs used to treat erectile dysfunction may also be associated with a reduced risk of Alzheimer’s disease, according to a study published in the February 7, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Nicolas Musi, MD, Named Inaugural Cypres Chair in Diabetes Research
Nicolas Musi, MD, studies a spectrum of age-related disorders that can impact a healthy lifespan.
Number of dementia cases could be 42% higher than previously estimated by 2040
Up to 1.7 million people could be living with dementia in England and Wales by 2040 – over 40% more than previously forecast – finds a new UCL-led study.
Study indicates possible link between chronic stress and Alzheimer’s disease
Researchers from Karolinska Institutet have published a study in Alzheimer’s Research & Therapy that addresses possible associations between chronic stress, mild cognitive impairment and Alzheimer’s disease.
A fitness tracker for brain health: How a headband can identify early signs of Alzheimer’s disease in your sleep
Researchers have identified a way to assess brain activity in sleep that occurs in the earliest stages of Alzheimer’s disease, typically many years prior to developing symptoms of dementia.
Can a Blood Test Detect Alzheimer’s Disease?
In July, the first direct-to-consumer blood test designed to assess a user’s risk for developing Alzheimer’s disease hit the market.
Small Percentage of People with Early Dementia Eligible for New Alzheimer’s Drugs
Only a small percentage of older adults who are in the early stages of Alzheimer’s disease meet the eligibility criteria to receive new monoclonal antibody treatments, drugs that target amyloid-ß plaques in the brain, an early sign of Alzheimer’s disease. The new research is published in the August 16, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. Clinical trial results for these drugs are only available in people in the early symptomatic stages of the disease, mild cognitive impairment or mild dementia due to Alzheimer’s disease.
Eat your vegetables to protect your brain
A new study published in the Journal of Alzheimer’s Disease by a Virginia Tech Carilion School of Medicine faculty member shows that brain levels of dietary lutein, zeaxanthin, lycopene, and vitamin E in those with Alzheimer’s disease are half those in normal brains. Higher dietary levels of lutein and zeaxanthin have been strongly linked to better cognitive functions and lower risk for dementia or Alzheimer’s disease.
New study shows anti-inflammatory drugs as a promising target for Alzheimer’s disease
A recent study from the lab of the University of Kentucky’s Sanders-Brown Center on Aging Director Linda Van Eldik, Ph.D., has been published in PLOS ONE. The work centers around the idea that various anti-inflammatory drugs could be effective treatments for Alzheimer’s disease (AD). This study focused on a protein known as p38.
‘Fastball’ test to detect Alzheimer’s earlier gets major £1.5 million funding boost
A simple but revolutionary test to improve early detection for dementia and Alzheimer’s disease could soon be helping patients and their families, thanks to a significant £1.5 million funding boost awarded to the universities of Bath and Bristol.
Stem cell model of human brain development suggests embryonic origins of Alzheimer’s disease
Alzheimer’s disease (AD) mainly affects the older population. Recent research found early disease signs in cell culture models of early human brain development, raising the possibility that the disease has its origins much earlier in life, possibly during embryogenesis – the formation and development of an embryo.
Mount Sinai Experts Present Research at SLEEP 2023
Sleep medicine experts from the Mount Sinai Health System are presenting new research at SLEEP 2023, the 37th annual meeting of the Associated Professional Sleep Societies running until June 7 in Indianapolis.
Having dementia and reduction in social participation are associated with increased depression and anxiety during the COVID-19 pandemic
An increased risk of depression and anxiety among US older adults with dementia and poor activity participation has been demonstrated through an analysis of data from the National Health and Aging Trends Study (NHATS), a nationally representative population-based study.
Mount Sinai Launches Institute for Regenerative Medicine
Institute, including three new centers, will lead research to foster novel discoveries and explore new treatments for a range of diseases from leukemia to Alzheimer’s disease.
Sugar molecule in blood can predict Alzheimer’s disease
Early diagnosis and treatment of Alzheimer’s disease requires reliable and cost-effective screening methods.
Using radar to predict Alzheimer’s disease and fall accidents
Researchers at Chalmers University of Technology in Sweden have developed a method for predicting fall accidents and cognitive illnesses such as Alzheimer’s disease by reading a person’s walking pattern with the aid of a radar sensor.
In patients with mild cognitive impairment, apathy can be a predictor of Alzheimer’s disease
The presence of apathy in patients with mild cognitive impairment is strongly linked to a progression to Alzheimer’s disease, giving physicians a possible early diagnosis tool, according to UTHealth Houston research published recently in the Journal of Alzheimer’s Disease.
$11M NIH Grant Will Support Evaluation of Alzheimer’s Screening Tool in Primary Care Settings
Investigators at Albert Einstein College of Medicine, Montefiore Health System, Regenstrief Institute, and Indiana University School of Medicine have received an $11 million grant from the National Institutes of Health (NIH) to evaluate an Einstein-developed test for assessing cognitive impairment and dementia.
Redesigning diabetes technology to detect low blood sugar in older adults with diabetes and Alzheimer’s disease
Regenstrief Institute Research Scientist April Savoy, PhD, a human factors engineer and health services researcher, is developing and testing user-friendly health information tools and technology designed to enhance accessibility and value to older adults with both diabetes and Alzheimer’s disease, and their caregivers.
Mount Sinai Researchers Use Artificial Intelligence to Uncover the Cellular Origins of Alzheimer’s Disease and Other Cognitive Disorders
Deep learning models represent “an entirely new paradigm for studying dementia”
Mayo Clinic expert provides tips for reducing dementia risk
More than 55 million people worldwide are believed to be living with dementia, according to the World Health Organization. Ronald Petersen, M.D., a neurologist and director of Mayo Clinic’s Alzheimer’s Disease Research Center, says you can’t prevent dementia, but you can reduce your risk.
Early Alzheimer’s detection up to 17 years in advance
The dementia disorder Alzheimer’s disease has a symptom-free course of 15 to 20 years before the first clinical symptoms emerge.
Investigational test may detect Alzheimer’s disease at early stages
Currently, the only accurate diagnosis of Alzheimer’s disease is through postmortem analyses after a patient dies, but investigators have now developed a highly sensitive method for quantifying levels of tau protein—a hallmark of the condition—in cerebrospinal fluid surrounding the brain and spinal cord.
Study Finds Untreated Sleep Apnea May Increase Risk for Neurodegenerative Disease, PAP Therapies Crucial in Treating the Sleep Condition
Mount Sinai researchers have conducted one of the first studies to show the acute effect of obstructive sleep apnea on Alzheimer’s disease biomarkers, and the ability to even measure Alzheimer’s disease biomarkers from blood.
UCI wins 5-year, $14M NIH grant to study brain circuits susceptible to aging, Alzheimer’s disease
Irvine, Calif., June 7, 2022 — The University of California, Irvine has been awarded a five-year, $14 million grant from the National Institutes of Health to study brain circuits that are susceptible to aging and Alzheimer’s disease. The research findings will advance the development of early diagnostic tools and the discovery of new treatment strategies.
KTU Researchers Investigate the Links Between Facial Recognition and Alzheimer’s Disease
In recent years Alzheimer’s disease has been on the rise throughout the world and is rarely diagnosed at an early stage when it can still be effectively controlled.
Single-cell DNA sequencing offers a new angle on the causes of Alzheimer’s disease
Alzheimer’s disease is marked by a loss of functional neurons in the brain.
Genetic changes differed, increased in people with Alzheimer’s disease
Inside brain cells, errors in DNA can accumulate as we age. But in patients with Alzheimer’s disease, these errors — known as somatic mutations — may build up at a faster rate.
Interferon drives cognitive impairment in Alzheimer’s disease model
Alzheimer’s disease (AD), the most common type of dementia, progressively impairs memory, concentration and the ability to learn new things and accomplish everyday activities.
Hope Builds for New Therapeutics to Reverse or Prevent Alzheimer’s
A new study from the University of Mississippi Medical Center in Jackson finds that (Aβ) accumulation in AD is associated with reduced blood flow to the brain, known as cerebral hypoperfusion.
Combination of biomarkers can identify common cognitive disease
In recent years, subcortical small-vessel disease has become an increasingly common cognitive diagnosis.
On repeat: Listening to favorite music improves brain plasticity, cognitive performance of Alzheimer’s patients, Toronto researchers find
Researchers at the University of Toronto (U of T) and Unity Health Toronto have demonstrated that repeated listening to personally meaningful music induces beneficial brain plasticity in patients with mild cognitive impairment or early Alzheimer’s disease.
New brain model provides patient-specific Alzheimer’s insights, predictions of cognitive decline
A study led by researchers from Brigham and Women’s Hospital has established a new resource for exploring and understanding Alzheimer’s disease (AD) on an individualized level.
Recent Study Identifies 11 Candidate Genetic Variants for Alzheimer’s Disease
A recently published study co-authored by University of Kentucky Sanders-Brown Center on Aging researcher Justin Miller, Ph.D., identifies 11 rare candidate variants for Alzheimer’s disease. Researchers found 19 different families in Utah that suffered from Alzheimer’s disease more frequently than what is considered normal.
Protein linked to heart health, disease a potential therapeutic target for dementia
Researchers at Washington University School of Medicine in St. Louis have found that high levels of a normal protein associated with reduced heart disease also protect against Alzheimer’s-like damage in mice, opening up new approaches to slowing or stopping brain damage and cognitive decline in people with Alzheimer’s.
Poor Sleep Predicts Long-term Cognitive Decline in Hispanics More So Than in Whites
Poor sleep impacts the risk of long-term cognitive decline in Hispanic/Latino middle aged and older adults differently than it does in non-Hispanic adults, according to research led by University of Miami Miller School of Medicine neurology faculty and the largest long-term study of U.S. Hispanic/Latinos to date.
FAU Researchers Receive Grants to Combat Alzheimer’s Disease in Florida
Four researchers from FAU’s Schmidt College of Medicine and Charles E. Schmidt College of Science have received grants totaling $641,818 from the Ed and Ethel Moore Alzheimer’s Disease Research Program.
Could leak in blood-brain barrier cause poor memory?
One of the keys to having a healthy brain at any age is having a healthy blood-brain barrier, a complex interface of blood vessels that run through the brain. Research shows the blood-brain barrier leaks as we age, and we lose cells called pericytes. But could this leak and the difficulties in recall be the early stages of Alzheimer’s disease?
Study: Treatable Sleep Disorder Common in People with Thinking and Memory Problems
Obstructive sleep apnea is when breathing is repeatedly interrupted during sleep. Research has shown people with this sleep disorder have an increased risk of developing cognitive impairment and Alzheimer’s disease. Yet, it is treatable. A preliminary study released today, February 28, 2021, has found that obstructive sleep apnea is common in people with cognitive impairment. The study will be presented at the American Academy of Neurology’s 73rd Annual Meeting being held virtually April 17 to 22, 2021.
Researchers Announce ‘Breakthrough’ in Treating Alzheimer’s Disease
Rockville, Md. (February 25, 2021)—Researchers from the University of Vermont’s Larner College of Medicine describe promising new results of an Alzheimer’s disease treatment study as a “breakthrough.” The study, conducted in mice, shows that a blood flow deficit in the…
People with Depression, Anxiety May Develop Alzheimer’s at Younger Age
Having depression is known to increase your risk for developing Alzheimer’s disease. Now a new, preliminary study released today, February 24, 2021, reports that if people do develop Alzheimer’s disease, those with depression may start experiencing dementia symptoms about two years earlier than those who do not have depression. People with anxiety who develop Alzheimer’s may start experiencing dementia symptoms about three years earlier than those who do not have anxiety, according to the study that will be presented at the American Academy of Neurology’s 73rd Annual Meeting being held virtually April 17 to 22, 2021.
Press and Media Registration is Open for 2021 AAN Annual Meeting
No matter where you are in the world, the 2021 AAN Annual Meeting is one click away. Journalists can now register to attend the 73rd Annual Meeting of the American Academy of Neurology (AAN) being held virtually April 17-22, 2021. The AAN Annual Meeting is the world’s largest gathering of neurologists who come together to share the latest advances in neurologic research.
Abnormal hyperactivation in the brain may be an early sign of Alzheimer’s
A research team led by psychology and neuroscience professor Sylvie Belleville has just targeted an early biomarker of the disease.
New Report Estimates 10,000 People 65 and Older Living with Dementia in the Nation’s Capital
A report released today estimates that about 10,000 Washington, D.C. residents 65 and older are living with dementia, a general term for a range of memory loss disorders, including Alzheimer’s disease.
Protein That Can Be Toxic in The Heart And Nerves May Help Prevent Alzheimer’s
A protein that wreaks havoc in the nerves and heart when it clumps together can prevent the formation of toxic protein clumps associated with Alzheimer’s disease, a new study led by a UT Southwestern researcher shows. The findings, published recently in the Journal of Biological Chemistry, could lead to new treatments for this brain-ravaging condition, which currently has no truly effective therapies and no cure.
Found: a genetic link to molecular events that precede symptoms in Alzheimer’s disease
Tufts researchers find a key mutation causing abnormal transport of BACE1, the enzyme responsible for processing the Alzheimer’s disease-linked amyloid protein. Identification of this mutation, which is more common among African Americans with Alzheimer’s, may allow early intervention.