UF, UF Health announce gift and new $75 million initiative to expand Norman Fixel Institute

The University of Florida and UF Health on Tuesday, Sept. 14, announced an additional $25 million gift from the Lauren and Lee Fixel Family Foundation aimed at improving the lives of patients across the globe through the Norman Fixel Institute for Neurological Diseases at UF Health. The new investment will spur growth in the areas of national and international telemedicine, Alzheimer’s disease clinical research, mental health, traumatic brain injury and ALS and will help cultivate the next generation of expert researchers tackling these challenging diseases.

People with Parkinson’s May Benefit from 7 Walking Strategies

Various strategies can help people with Parkinson’s who have difficulty walking, but a new study finds that many people have never heard of or tried these strategies. The research is published in the September 8, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study also found that how well different compensation strategies worked depended on the context in which they were used, such as indoors versus outdoors, under time pressure or not.

New Study Provides Structural Insights into How Cholesterol in the Brain Regulates Ion Channels and Alters Their Function; Findings Could Facilitate the Development of Therapeutics for Neurological Diseases

UNDER EMBARGO UNTIL 11am EST on August 24: Cell Reports   Senior Author: Paul A. Slesinger, PhD, Lillian and Henry M. Stratton Professor of Neuroscience and Director of the Center for Neurotechnology and Behavior, Icahn School of Medicine at Mount Sinai,…

Hopkins Med News Update

NEWS STORIES IN THIS ISSUE:

-Study: Race and Ethnicity May Impact Prevalence and Treatment of Heart Valve Dysfunction
-Johns Hopkins Medicine Suggests Eliminating Nerve Cell Protein May Stop ALS, Dementia
-Researchers Tell Doctors to Avoid Routine Urinary Tests for Older Patients with Delirium
-Johns Hopkins Medicine Researchers Show How Air Pollution May Cause Chronic Sinusitis
-Researchers ID Location on Brain Protein Linked to Parkinson’s Disease Development
-COVID-19 News: The Return of Onsite Schooling — and How to Keep Your Kids Safe from COVID

Parkinson’s disease: How lysosomes become a hub for the propagation of the pathology

Over the last few decades, neurodegenerative diseases became one of the top 10 global causes of death. Researchers worldwide are making a strong effort to understand neurodegenerative diseases pathogenesis, which is essential to develop efficient treatments against these incurable diseases.…

Adult ADHD is linked to numerous physical conditions

Adults with ADHD are at higher risk of a wide range of physical conditions, including nervous system, respiratory, musculoskeletal, and metabolic diseases, according to a large register-based study from Karolinska Institutet in Sweden published in The Lancet Psychiatry . “Identifying…

Engineered Neural Networks Help ID Responses Associated with Abnormalities in Parkinson’s Disease

Article title: Early functional changes associated with alpha-synuclein proteinopathy in engineered human neural networks Authors: Vibeke D. Valderhaug, Kristine Heiney, Ola Huse Ramstad, Geir Bråthen, Wei-Li Kuan, Stefano Nichele, Axel Sandvig, Ioanna Sandvig From the authors: “In this study, we investigate the…

Henry Ford Health System Therapeutic Choir Finds Its Voice Through COVID-19

DETROIT – Henry Ford Health System is using the healing power of singing to help patients with voice disorders that result from various medical conditions such as Parkinson’s disease, stroke and vocal cord paralysis to help improve their voices. Patients in a therapeutic choir called the Motor City Upbeats regain their vocal strength and range and breathing through a series of simple exercises and techniques taught in a welcoming, cheerful environment where just hearing the sound of your voice is music to the ears.

Will reduction in tau protein protect against Parkinson’s and Lewy body dementias?

A study suggests that reducing tau protein in brain neurons will not protect against Parkinson’s disease and Lewy body dementias. If borne out, this result differs from Alzheimer’s disease, where reducing endogenous tau levels in brain neurons is protective for multiple models of the disease.

After 15 Years, Deep Brain Stimulation Still Effective in People with Parkinson’s

Deep brain stimulation continues to be effective in people with Parkinson’s disease 15 years after the device is implanted, according to a study published in the June 2, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology. Researchers found that compared to before deep brain stimulation, study participants continued to experience significant improvement in motor symptoms, which are symptoms that affect movement, as well as a reduction in medications 15 years later.

Deciphering Gene-Environment Interactions in Parkinson’s Disease

The interaction between an individual’s genetics and their local environment plays a critical role in an individual’s likelihood of getting Parkinson’s disease. In this perspective, researchers highlight how a common fly could be used to better understand the complex interactions…

New algorithm could help enable next-generation deep brain stimulation devices

PROVIDENCE, R.I. [Brown University] — By delivering small electrical pulses directly to the brain, deep brain stimulation (DBS) can ease tremors associated with Parkinson’s disease or help relieve chronic pain. The technique works well for many patients, but researchers would…

Novel approaches in treating neurodegenerative disorders

The central nervous system (CNS) is the most vital component of our body, regulating various kinds of daily activities that are essential for our life processes. Keeping the balance between body and brain and maintaining the homeostasis of CNS is…