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UrduResearchers are gaining new insights into neurological diseases by studying circular RNAs (circRNAs) in brain cells.
Tag: Parkinson’s Disease
“Stereotyped, devalued and shunned.” Experts address treating the stigma of Parkinson’s disease
Even the best treatment approaches for Parkinson’s disease are inadequate if they do not address patients’ feelings of social rejection, isolation, loneliness and other psychosocial effects of stigma, according to a report from experts specializing in Parkinson’s and other movement disorders.
Can a Blood Test Detect Alzheimer’s Disease?
In July, the first direct-to-consumer blood test designed to assess a user’s risk for developing Alzheimer’s disease hit the market.
FAU and Insightec Partner to Use Focused Ultrasound to Treat Neurological Disorders
This agreement will enable FAU and Insightec to collaborate to advance scientific knowledge about the use of focused ultrasound to treat brain diseases, including Parkinson’s disease and Alzheimer’s disease. By harnessing acoustic energy, Insightec’s innovative technology uses focused ultrasound to treat diseases in different ways.
NeuroPoint Alliance’s Registry for the Advancement of DBS in Parkinson’s Disease Successfully Completes Pilot Phase
NeuroPoint Alliance’s (NPA) Registry for the Advancement of DBS in Parkinson’s Disease (RAD-PD) has successfully completed its Pilot Phase by achieving all data collection goals established at the beginning of registry creation.
Study: Misfolded alpha-synuclein protein key to early detection of Parkinson’s disease
The presence of a misfolded alpha-synuclein protein can be used to determine if people have Parkinson’s disease, according to a new study using technology developed by a researcher at UTHealth Houston. This biomarker could pave the way for the development of better diagnostic tools and new treatment options for the disease.
What Is Parkinson’s Disease? 10 Things to Know
Here are the history, symptoms, causes and treatment options for Parkinson’s.
For People with Parkinson’s Disease, Quality of Life Linked to Race, Ethnicity
Among those living with Parkinson’s disease, Black, Hispanic and Asian people were found to have a lower health-related quality of life than white people, according to a new study published in the April 5, 2023, online issue of Neurology® , the medical journal of the American Academy of Neurology.
New Focused Ultrasound Effective for treating Parkinson’s, Movement Disorders
In a study published in the New England Journal of Medicine co-authored by Vibhor Krishna, MD, associate professor of neurosurgery at the UNC School of Medicine, researchers show that a new focused ultrasound treatment improved dyskinesia and motor impairment in patients with Parkinson’s disease.
Study Finds Air Pollution Exposure Linked to Parkinson’s Risk, Identifies U.S. Hot Spot
Living in areas of the United States with higher levels of air pollution is associated with an increased risk of Parkinson’s disease, according to a preliminary study released today, February 23, 2023, that will be presented at the American Academy of Neurology’s 75th Annual Meeting being held in person in Boston and live online from April 22-27, 2023.
Nanopore-Based Sensing Device Explores Neurodegenerative Diseases
In Journal of Applied Physics, researchers present a special silicon nitride nanopore-based sensing device that is designed to provide volume information about tau and tubulin protein molecules and their aggregation states. To create the sensor, the team explored how the proteins change the current and voltage flowing through a nanopore system.
New blood test can detect ‘toxic’ protein years before Alzheimer’s symptoms emerge, study shows
Researchers can detect small “toxic” aggregates of a particular protein in the blood of individuals with Alzheimer’s disease and in individuals who showed no signs of cognitive impairment at the time the blood sample was taken, but who developed it at a later date.
Review: Are Climate Change and Air Pollution Making Neurologic Diseases Worse?
People with neurologic diseases like headache, dementia, multiple sclerosis (MS) and Parkinson’s disease may experience worsening symptoms due to climate change, according to a scoping review of research published in the November 16, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Cecilia Lindestam Arlehamn wins WHAM Edge Award funding to study sex-based differences in Alzheimer’s and Parkinson’s diseases
Cecilia Lindestam Arlehamn, Ph.D., aims to shed light on how sex-based immune system differences may affect the development and progression of these neurodegenerative diseases in men versus women.
Today: ANA2022 Media Roundtable to Spotlight Latest in Neuro Research
As the American Neurological Association’s 147th Annual Meeting wraps up today, October 25, the ANA is holding a Media Roundtable at 11 a.m. U.S. Central for reporters to access the latest developments in neurology and neuroscience.
An Environmental Wake-Up Call for Neurology
The Presidential Symposium at the American Neurological Association’s 2022 Annual Meeting (ANA2022) in Chicago will shine a spotlight on the role of environmental exposures — air pollution, pesticides, microplastics, and more — in diseases like dementias and developmental disorders.
American Neurological Association Publishes Research Abstracts for ANA2022, Oct. 22–25 in Chicago
Abstracts of breaking research in neurology and neuroscience, to be presented at the 2022 American Neurological Association Annual Meeting Oct. 22-25, are now available in Annals of Neurology and on the ANA2022 website.
Parkinson’s Disease: Uncovering Why Nicotine May Be Protective (for Some)
Parkinson’s disease is caused by a combination of genetic and environmental factors, one curious example being that people who smoke appear to be less likely to develop Parkinson’s. This may be due to interactions between nicotine and genetic variations in…
Multiple System Atrophy: Identifying Cells that Accelerate Disease Progression
There is currently no cure for the rare neurodegenerative disorder multiple system atrophy (MSA), and its rarity has made it difficult to understand how the disease progresses. Now a research team has created a successful mouse model of aggressive cerebellar-type…
Exercise Hormone Halts Parkinson’s Disease Symptoms in Mouse Study
Researchers from Johns Hopkins Medicine and the Dana Farber Cancer Institute in Boston have shown that a hormone secreted into the blood during endurance, or aerobic, exercise reduces levels of a protein linked to Parkinson’s disease and halts movement problems in mice.
Mayo Clinic Healthcare expert explains when swallowing issues are more than an accident
Many people have experienced the discomfort of food or a beverage accidentally going to the wrong place when swallowing. But swallowing issues sometimes become chronic and may be a sign of a health condition that should be treated.
World-First: A Biomarker That Can Diagnose Parkinson’s Disease
Researchers at Kobe University and Hiroshima University have successfully developed a biomarker that will enable Parkinson’s disease to be rapidly and inexpensively diagnosed from blood serum samples.
May Research Highlights
A Roundup of the Latest Medical Discoveries and Faculty News at Cedars-Sinai
‘Sting’ Protein’s Efforts to Clean Up Brain Cell Damage May Speed Parkinson’s Disease Progress
In studies with mouse and human tissue, as well as live mice, Johns Hopkins Medicine researchers report that a snag in the normal process of cleaning up broken DNA in brain cells may hasten the progression of Parkinson’s disease.
UTHealth Houston’s UTMOVE program receives distinguished Edmond J. Safra Fellowship in Movement Disorders
UTHealth Houston’s Movement Disorders and Neurodegenerative Diseases Fellowship Training Program (UTMOVE fellowship program) has been chosen by The Michael J. Fox Foundation for Parkinson’s Research (MJFF) as one of eight international academic centers to train a new movement disorder clinician-researcher — a neurologist with additional training and expertise in diagnosing and treating Parkinson’s and related diseases — as part of the Edmond J. Safra Fellowship in Movement Disorders Class of 2025.
April is Parkinson’s Disease Awareness Month
Parkinson’s Disease Awareness month is dedicated to raising awareness and support for patients suffering from this progressive brain disorder. Learn more about Parkinson’s disease, treatment options and support for those with Parkinson’s.
Vascular Defects Appear to Underlie the Progression of Parkinson’s Disease
In an unexpected discovery, Georgetown University Medical Center researchers have identified what appears to be a significant vascular defect in patients with moderately severe Parkinson’s disease. The finding could help explain an earlier outcome of the same study, in which the drug nilotinib was able to halt motor and non-motor (cognition and quality of life) decline in the long term.
Study: Death Rate from Parkinson’s Rising in U.S.
A new study shows that in the last two decades the death rate from Parkinson’s disease has risen about 63% in the United States. The research is published in the October 27, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study also found that the death rate was twice as high in men as in women, and there was a higher death rate in white people than other racial/ethnic groups.
UC San Diego-Led Team Receives $9M to Advance Parkinson’s Disease Treatments
A new $9 million grant from Aligning Science Across Parkinson’s (ASAP) will enable advancement of UC San Diego’s discovery that inhibiting a single gene in mice converts other cell types directly into new neurons, alleviating all Parkinson’s symptoms.
Early-Stage Drug Candidate Diminishes Deficits in Parkinson’s Disease
University of Utah Health scientists have identified a molecule that slows cells’ production of alpha-synuclein, a protein that forms toxic aggregates in the brains of people with Parkinson’s disease. Its discovery points toward a new strategy for treating the disease and potentially stopping its progression.
Nasal Drugs Show Promise for Slowing Parkinson’s Disease Progression in Lab Study
Rush researchers have shown that two lab-developed and nasally-delivered peptides helped slow the spread of alpha-synuclein in mice.
UF, UF Health announce gift and new $75 million initiative to expand Norman Fixel Institute
The University of Florida and UF Health on Tuesday, Sept. 14, announced an additional $25 million gift from the Lauren and Lee Fixel Family Foundation aimed at improving the lives of patients across the globe through the Norman Fixel Institute for Neurological Diseases at UF Health. The new investment will spur growth in the areas of national and international telemedicine, Alzheimer’s disease clinical research, mental health, traumatic brain injury and ALS and will help cultivate the next generation of expert researchers tackling these challenging diseases.
Jersey Shore University Medical Center Welcomes Shabbar Danish, MD, as Chair of Neurosurgery
Hackensack Meridian Jersey Shore University Medical Center recently welcomed Board Certified Neurosurgeon Shabbar F. Danish, M.D., FAANS, as Chair of Neurosurgery as part of the academic medical center’s Neuroscience Institute.
People with Parkinson’s May Benefit from 7 Walking Strategies
Various strategies can help people with Parkinson’s who have difficulty walking, but a new study finds that many people have never heard of or tried these strategies. The research is published in the September 8, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study also found that how well different compensation strategies worked depended on the context in which they were used, such as indoors versus outdoors, under time pressure or not.
New Study Provides Structural Insights into How Cholesterol in the Brain Regulates Ion Channels and Alters Their Function; Findings Could Facilitate the Development of Therapeutics for Neurological Diseases
UNDER EMBARGO UNTIL 11am EST on August 24: Cell Reports Senior Author: Paul A. Slesinger, PhD, Lillian and Henry M. Stratton Professor of Neuroscience and Director of the Center for Neurotechnology and Behavior, Icahn School of Medicine at Mount Sinai,…
Hopkins Med News Update
NEWS STORIES IN THIS ISSUE:
-Study: Race and Ethnicity May Impact Prevalence and Treatment of Heart Valve Dysfunction
-Johns Hopkins Medicine Suggests Eliminating Nerve Cell Protein May Stop ALS, Dementia
-Researchers Tell Doctors to Avoid Routine Urinary Tests for Older Patients with Delirium
-Johns Hopkins Medicine Researchers Show How Air Pollution May Cause Chronic Sinusitis
-Researchers ID Location on Brain Protein Linked to Parkinson’s Disease Development
-COVID-19 News: The Return of Onsite Schooling — and How to Keep Your Kids Safe from COVID
Fruit Compound May Have Potential to Prevent and Treat Parkinson’s Disease, Mouse Study Suggests
Johns Hopkins Medicine researchers say they have added to evidence that the compound farnesol, found naturally in herbs, and berries and other fruits, prevents and reverses brain damage linked to Parkinson’s disease in mouse studies.
Device cracks milk protein
‘Refolding’ molecules to support medical solutions
Parkinson’s disease: How lysosomes become a hub for the propagation of the pathology
Over the last few decades, neurodegenerative diseases became one of the top 10 global causes of death. Researchers worldwide are making a strong effort to understand neurodegenerative diseases pathogenesis, which is essential to develop efficient treatments against these incurable diseases.…
Digital health technologies hold key to new Parkinson’s treatments
Global stakeholders come together to collaborate with urgency to address unmet needs for Parkinson’s therapies
Digital technology driving tangible advancements in Parkinson’s disease research and clinical care
In this new supplement to the Journal of Parkinson’s Disease experts report on how digital technology is being used to reshape research and clinical care in Parkinson’s disease
Chemists Found an Effective Remedy For “Aged” Brain Diseases
Russian scientists have synthesized chemical compounds that can stop the degeneration of neurons in Alzheimer’s, Parkinson’s, and other severe brain pathologies.
A Trojan horse could help get drugs past our brain’s tough border patrol
Sclerosis, Parkinson’s Disease, Alzheimer’s and epilepsy are but a few of the central nervous system disorders. They are also very difficult to treat, since the brain is protected by the blood-brain barrier. The blood-brain barrier works as a border wall…
UCPH researchers prove powerhouse malfunction as the major cause of Parkinson’s Disease
12,000 people in Denmark and 7 to 10 million people worldwide suffer from Parkinson’s Disease (PD). It is the second most common neurogenerative disorder of aging and the most common movement disorder, but the cause of the disease is largely…
Identified an early neuronal dysfunction in Parkinson’s that could help early diagnosis
Researchers from IDIBELL and the University of Barcelona (UB) have described that neurons derived from Parkinson’s patients show impairments in their transmission before neurodegeneration.
Dancing with music can halt most debilitating symptoms of Parkinson’s disease
A new study published in Brain Sciences today, shows patients with mild-to-moderate Parkinson’s disease (PD) can slow the progress of the disease by participating in dance training with music for one-and-a-quarter hours per week.
New Alzheimer’s treatment targets identified
A research team at Washington University School of Medicine in St. Louis has identified potential new treatment targets for Alzheimer’s disease, as well as existing drugs with therapeutic potential.
Brain mapping method illuminates targets for treating neuropsychiatric symptoms
Novel approach finds targets for future clinical trials in depression and Parkinson’s disease
Identified an early neuronal dysfunction in Parkinson’s that could help early diagnosis
Researchers from IDIBELL and the University of Barcelona (UB) have described that neurons derived from Parkinson’s patients show impairments in their transmission before neurodegeneration. For this study, it has been used dopaminergic neurons differentiated from patient stem cells as a…
Dancing with music can halt most debilitating symptoms of Parkinson’s disease
First-of-its-kind York U study shows participating in weekly dance training improves daily living and motor function for those with mild-to-moderate Parkinson’s