Binghamton University biologist named Fellow of American Academy of Microbiology

Binghamton University, State University of New York researcher Karin Sauer is among 65 scientists elected as Fellows of the American Academy of Microbiology this year. Fellows are elected by their peers based on their scientific achievements and original contributions to the field of microbiology.

RUDN pharmacists proposed ways to increase the activity of levofloxacin and overcome bacterial resistance to antimicrobial agents

RUDN University pharmacists modeled derivative molecules of the antibacterial levofloxacin to find out what biological functions its individual structural fragments – pharmacophores – are responsible for. This is necessary to increase the effectiveness of the drug, as bacteria become increasingly resistant to antibiotics.

SLU Study: Head and Neck Cancer Diagnostic Delays Linked to Antibiotics Despite Clinical Practice Guidelines

Researchers at Saint Louis University School of Medicine say diagnostic delays frequently occur in patients with undiagnosed head and neck cancer (HNC) and are calling for improved dissemination of current clinical practice guidelines in a new paper published Aug. 24 in JAMA Otolaryngology – Head & Neck Surgery.

A potential new weapon in the war against superbugs

For nearly 25 years, Dr. James Kirby has worked to advance the fight against infectious diseases by finding and developing new, potent antimicrobials, and by better understanding how disease-causing bacteria make us sick. In a recent paper published in PLOS Biology, Kirby and colleagues investigated a naturally occurring antimicrobial agent discovered more than 80 years ago.

Routine antibiotics don’t improve outcomes of post-mastectomy breast reconstruction

For breast cancer patients undergoing breast reconstruction after mastectomy, avoiding postoperative oral antibiotics does not reduce the risk of infections, reports a study in the May issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS). The journal is published in the Lippincott portfolio by Wolters Kluwer.

UAlbany Researchers Awarded $1.4M to Identify RNAs Linked to Cancer and Bacterial Infections

Researchers from The RNA Institute at the University at Albany have been awarded $1.4 million to investigate stress-induced RNA modifications and associated cell response. The focus of the study — “wobble uridines” in tRNA — could hold important clues for treating bacterial infections and detecting cancer.

Dietary supplementation may improve antibiotic-induced GVHD following stem cell transplants

Researchers at The University of Texas MD Anderson Cancer Center have identified a specific gut bacterium involved in the progression of graft-versus-host disease (GVHD) after antibiotic treatment of allogeneic hematopoietic stem cell transplantation (allo-HSCT) and discovered that nutritional supplementation can prevent antibiotic-induced GVHD in preclinical models, according to a study published today in Cell.

New drug candidate fights off more than 300 drug-resistant bacteria

Urinary tract infections are common, yet can be tough to treat as the bacteria that cause them become resistant to many antibiotics. In ACS Central Science, researchers report a new molecule that inhibits drug-resistant bacteria in lab experiments, as well as in mice with pneumonia and UTIs.

Mystery mechanism in small peptide shows big promise for fighting antibiotic-resistant bacteria

Using neutrons, researchers at Oak Ridge National Laboratory pieced together the molecular mechanics behind a peptide’s ability to deal significant damage to bacterial cells. Their findings could inform new therapeutic strategies for treating bacterial infections where antibiotics have fallen short.

Antibiotic resistance outwitted by supercomputers

Scientists may have made a giant leap in fighting the biggest threat to human health by using supercomputing to keep pace with the impressive ability of diseases to evolve.
A new study by an international team, co-led by Dr Gerhard Koenig from the University of Portsmouth, tackled the problem of antibiotic resistance by redesigning existing antibiotics to overcome bacterial resistance mechanisms.

Science Snapshots from Berkeley Lab

An experiment to study gravity at the quantum scale, insights into an antibiotic-building enzyme, and the backstory of an incredible new protein prediction algorithm are featured in this month’s roundup of science highlights.