New Algorithm Tracks Pediatric Sepsis Epidemiology Using Clinical Data

Researchers at Children’s Hospital of Philadelphia (CHOP) have developed a novel computational algorithm to track the epidemiology of pediatric sepsis, allowing for the collection of more accurate data about outcomes and incidence of the condition over time, which is essential to the improvement of care.

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Vitamin C-B1-Steroid Combo Linked to Lower Septic Shock Mortality in Kids

Treating septic shock in children with a combination of intravenous vitamin C, vitamin B1 and hydrocortisone (a commonly used steroid) is associated with lower mortality, according to a study from Ann & Robert H. Lurie Children’s Hospital of Chicago. This is the first pediatric study of the safe and relatively inexpensive treatment for septic shock, and the preliminary data supports the promising outcomes seen in adults. Findings were published in the American Journal of Respiratory and Critical Care Medicine.

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For Patients with Sepsis, an Infectious Disease Expert May Reduce the Risk of Death

When people with severe sepsis, an extreme overreaction by the body to a serious infection, come to the emergency room (ER), they require timely, expert care to prevent organ failure and even death. When that care includes the early involvement of an infectious disease (ID) specialist, patient mortality can be reduced by as much as 40 percent, according to a new retrospective, single-center study published in Open Forum Infectious Diseases.

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Antibody Improves Survival from Sepsis-Related Fungal Infections in Mice

An antibody that blocks the “programmed cell death” pathway may help the immune system fight off sepsis-related fungal infections, according to animal studies reported in SHOCK®: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches, Official Journal of the Shock Society. The journal is published in the Lippincott portfolio by Wolters Kluwer.

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