Investigational COVID-19 vaccine candidate prevents severe clinical disease in animals

In new research published in Nature Medicine, Beth Israel Deaconess Medical Center immunologist Dan H. Barouch, MD, PhD, and colleagues demonstrated that the optimal vaccine elicited robust immune response in Syrian golden hamsters and prevented severe clinical disease — including weight loss, pneumonia and death.

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Scientists Aim Gene-Targeting Breakthrough Against COVID-19

Scientists at Berkeley Lab and Stanford have joined forces to aim a gene-targeting, antiviral agent called PAC-MAN against COVID-19.

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Blood Test Indicators of Infection Response Do Not Generally Predict Severity of Community-Acquired Pneumonia in Children

Blood biomarkers that reflect the body’s response to infection – including white blood cell count, absolute neutrophil count, C-reactive protein (CRP) and procalcitonin – are generally not useful in predicting the overall severity of community-acquired pneumonia in children, according to a study published in Pediatrics.

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Arthritis Drug Presents Promise as Treatment for COVID-19 Pneumonia

UC San Diego Health has launched a Phase III clinical trial to assess whether a medication used to treat rheumatoid might also have therapeutic value for patient with COVID-19 who have developed or are at high risk of developing serious lung damage from SARS-CoV-2 infections.

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Artificial Intelligence Enables Rapid COVID-19 Lung Imaging Analysis at UC San Diego Health

With support from Amazon Web Services, UC San Diego Health physicians are using AI in a clinical research study aimed at speeding the detection of pneumonia, a condition associated with severe COVID-19.

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Scientists May Have a Way to Let Preemies Breathe Easier

The continuing epidemic of pre-term birth includes this stark reality: tiny, fragile babies are born with underdeveloped lungs and prone to lifelong respiratory infections and related chronic illnesses. Cincinnati Children’s researchers report in Immunology the discovery of a complex biological process could in the development of cost effective treatments to help babies develop lifelong pulmonary resistance to respiratory infections.

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