An AI-based analysis of over 2 million hospital visits has found that most pneumonia diagnoses made in the hospital will change from a patient’s entrance to their discharge; clinical notes on pneumonia diagnoses reflect similarly high uncertainty.
Tag: Pneumonia
Initial pneumonia diagnoses often revised in the hospital
A national cohort study representing more than 2 million patient encounters found that more than half of all patients hospitalized and treated for pneumonia experienced discordant diagnoses from their initial presentation to discharge.
Vaccinologists Keith Klugman and Shabir Madhi awarded Sabin’s Prestigious Gold Medal
The Sabin Vaccine Institute presented the Albert B. Sabin Gold Medal to physician-researchers Keith Klugman and Shabir Madhi.
Study provides new insights into deadly acute respiratory distress syndrome (ARDS)
Researchers at the University of Minnesota Twin Cities may have discovered a mechanical explanation for instability observed in the lungs in cases of acute respiratory distress syndrome (ARDS), particularly in the aftermath of respiratory illnesses such as COVID-19 or pneumonia.
Leave No One Behind: The Forum of International Respiratory Societies Calls for Equitable Access to Prevention and Treatment on World Lung Day 2023
This World Lung Day, Sept. 25, the Forum of International Respiratory Societies (FIRS) and its founding member the American Thoracic Society, is calling on governments and health care providers worldwide to give equitable access to preventative services and treatments for respiratory conditions, and lifesaving pneumonia vaccines for children.
Five New Health Systems Partner with American Thoracic Society on Vaccine Initiative
As cities brace for a confluence of flu, COVID-19, pneumonia, and RSV infections this fall, the American Thoracic Society announced that five new health systems have partnered with the Society to improve vaccination rates.
Getting vaccines for flu, RSV, pneumonia and COVID.
David Winter, MD, at Baylor Scott & White Health, answers the most common patient questions and reacts to the latest medical research. With flu season approaching, who should get a flu shot and when? (SOT@ :14, TRT :24) RSV cases…
Several vaccines associated with reduced risk of Alzheimer’s disease in adults 65 and older
Prior vaccination against tetanus and diphtheria, with or without pertussis (Tdap/Td); herpes zoster (HZ), better known as shingles; and pneumococcus are all associated with a reduced risk for developing Alzheimer’s disease, according to new research from UTHealth Houston.
Kentucky physician explores new pediatric care protocols in developing nations
George Fuchs, M.D., a pediatric gastroenterologist at Kentucky Children’s Hospital, conducted a years-long trial in Bangladesh testing a model of healthcare delivery for children with pneumonia. The results have the potential to change pediatric care in developing nations.
NIH-Funded Research to Develop Pneumonia Severity Prediction Tool to Improve Emergency Care of Children
Todd Florin, MD, MSCE, from Ann & Robert H. Lurie Children’s Hospital of Chicago recently was awarded a $5.8 million grant from the National Heart, Lung, and Blood Institute (NHLBI) for a multicenter study to derive and broadly validate the first emergency department (ED)-based pediatric community-acquired pneumonia severity (PedCAPS) score. This objective score will help avoid many unnecessary hospitalizations in children at low risk of severe outcomes, while targeting more focused therapies towards the lower proportion of children at highest risk for severe disease.
Cystic fibrosis drug could help treat pneumonia
Pathogens such as SARS-CoV-2 and pneumococcus can cause severe pneumonia. If the airways then fill with fluid, the patient risks developing acute respiratory distress syndrome.
Machine Learning Diagnoses Pneumonia by Listening to Coughs #ASA183
Researchers have developed a machine learning algorithm to identify cough sounds and determine whether the subject is suffering from pneumonia. Because every room and recording device is different, they augmented their recordings with room impulse responses, which measure how the acoustics of a space react to different sound frequencies. By combining this data with the recorded cough sounds, the algorithm can work in any environment.
Remdesivir reduces COVID-19 mortality in a real-world setting
The COVID-19 pandemic has led to an explosion of clinical research resulting in the development of a variety of vaccines and treatments, although the efficacy of some remains controversial.
Physicians urged to consider fungal infections as possible cause for lung inflammation
UC Davis Health infectious diseases expert George Thompson warns of the rising threat and apparent spread of disease-causing fungi outside their traditional hot spots. Fungal lung infections are commonly misdiagnosed, leading to delays in treatment and increase in antimicrobial resistance in the community.
Study shows superbugs in the environment rarely transfer over to humans: Hospitals are more risky than farms
An international team of scientists investigating transmission of a deadly drug resistant bacteria that rivals MRSA, has found that whilst the bugs are found in livestock, pets and the wider environment, they are rarely transmitted to humans through this route.
Forum of International Respiratory Societies Calls for Collaborative Efforts to Fight Pneumonia
This World Pneumonia Day, Nov. 12, 2022, the Forum of International Respiratory Societies (FIRS), of which the American Thoracic Society is a founding member, is calling on governments and other stakeholders to take urgent action to tackle pneumonia – focusing on those who are at greatest risk of severe illness.
Tiny swimming robots treat deadly pneumonia in mice
UC San Diego engineers have developed microscopic robots, called microrobots, that can swim around in the lungs, deliver medication and be used to clear up life-threatening cases of bacterial pneumonia. In mice, the microrobots safely eliminated pneumonia-causing bacteria in the lungs and resulted in 100% survival. By contrast, untreated mice all died within three days after infection.
MedStar Washington Hospital Center Again Named Among Nation’s Top 50 for Heart Care
MedStar Washington Hospital Center has again achieved national ranking for Cardiology & Heart Surgery in the 2022-23 U.S. News & World Report “Best Hospitals” rankings. It moved up to No. 28, from No. 30 last year. It is the only nationally recognized heart program of its kind in the Washington metropolitan area. MedStar Washington also earned “high performing” ratings in cancer, gastroenterology & GI surgery, Urology, and in 12 common procedures and conditions.
Global Efforts Must Be Strengthened to End the Preventable Burden of Pneumonia: The Forum of International Respiratory Societies
On World Pneumonia Day, Nov. 12, the Forum of International Respiratory Societies (FIRS), of which the American Thoracic Society is a founding member, calls for urgent and expedited progress to end the preventable burden of pneumonia.
Study Is First to Examine Fibrocyte Levels in People Hospitalized with COVID-19 Pneumonia
Article title: Blood fibrocytes are associated with severity and prognosis in COVID-19 pneumonia Authors: Mada Ghanem, Méline Homps-Legrand, Marc Garnier, Lise Morer, Tiphaine Goletto, Justine Frija-Masson, Paul-Henri Wicky, Pierre Jaquet, Catherine Bancal, Margarita Hurtado-Nedelec, Luc de Chaisemartin, Madeleine Jaillet, Arnaud…
Heparin-based Blood Purification Protects Baboon Kidneys in Severe Pneumonia, Sepsis
Article title: Heparin-based blood purification attenuates organ injury in baboons with S. pneumoniae pneumonia Authors: Lingye Chen, Bryan D. Kraft, Victor L. Roggli, Zachary R. Healy, Christopher W. Woods, Ephraim L. Tsalik, Geoffrey S. Ginsburg, David M. Murdoch, Hagir B.…
This stinks: New research finds sense of smell and pneumonia linked
An acute loss of smell is one of the most common symptoms of COVID-19, but for two decades it has been linked to other maladies among them Parkinson’s disease and dementia. Now, a poor sense of smell may signify a higher risk of pneumonia in older adults, says a team of Michigan State University researchers.
New study suggests pregnant women hospitalized for COVID-19 do not face increased risk of death
Pregnant women who are hospitalized with COVID-19 and viral pneumonia are less likely than non-pregnant women to die from these infections, according to a new study by researchers with The University of Texas Health Science Center at Houston (UTHealth) and the University of Maryland School of Medicine (UMSOM).
New Clinical Practice Guideline on Community Acquired Pneumonia;
In its latest clinical practice guideline on community-acquired pneumonia the American Thoracic Society’s guidelines panel addresses the use of nucleic acid-based testing for non-influenza viral pathogens. The guideline was published online in the May 1 issue of the American Journal of Respiratory and Critical Care Medicine. An explainer video may be viewed here.
Can Doctors Predict Which Children with Pneumonia Will Develop Mild or Severe Disease?
Currently, there are no evidence-based rules that help physicians in the Emergency Department (ED) predict if a child with community-acquired pneumonia will have a mild disease course that can be treated at home or a more severe illness that requires hospitalization. A recent study published in the journal Pediatrics found that the predictive accuracy of clinical judgement was generally fair, but clinicians were least accurate when predicting progression to severe disease in children initially classified as having “low to moderate” risk, which accounts for a large portion of children presenting with pneumonia.
Five days of antibiotics fine for children with pneumonia
The study, involving 281 Ontario children, found that 85.7% of those who received the short course of antibiotics and 84.1% of those who received the longer course of medication were cured two to three weeks later.
Amount of COVID Viral RNA Detected at Hospital Admission Predicts How Patients Will Fare
A new study published online in the Annals of the American Thoracic Society examines whether the amount of RNA, or genomic load, of SARS-CoV-2 detected in swab tests of patients being admitted to the hospital with viral pneumonia is associated with more severe COVID-19. SARS-CoV-2 is the virus that causes COVID-19. Previous studies on this question have had conflicting results.
.@UChicagoMedicine experts can discuss #Tocilizumab research; Drug may reduce need for ventilators in #COVID19 pneumonia
Roche made news today as research showed its drug (tocilizumab) reduced patients’ need for ventilators for those with COVID-19-associated pneumonia. A University of Chicago Medicine team has done separate, independent research on tocilizumab and found similar results in their own phase II trial.…
Investigational COVID-19 vaccine candidate prevents severe clinical disease in animals
In new research published in Nature Medicine, Beth Israel Deaconess Medical Center immunologist Dan H. Barouch, MD, PhD, and colleagues demonstrated that the optimal vaccine elicited robust immune response in Syrian golden hamsters and prevented severe clinical disease — including weight loss, pneumonia and death.
Researchers study whether vadadustat, an investigational therapy, could mitigate acute lung injury in COVID-19 patients
Physicians are studying whether vadadustat, an investigational therapy, could protect the lungs of COVID-19 patients by triggering the body’s protective response to low oxygen levels in a randomized Phase II clinical trial at UTHealth.
Scientists Aim Gene-Targeting Breakthrough Against COVID-19
Scientists at Berkeley Lab and Stanford have joined forces to aim a gene-targeting, antiviral agent called PAC-MAN against COVID-19.
Blood Test Indicators of Infection Response Do Not Generally Predict Severity of Community-Acquired Pneumonia in Children
Blood biomarkers that reflect the body’s response to infection – including white blood cell count, absolute neutrophil count, C-reactive protein (CRP) and procalcitonin – are generally not useful in predicting the overall severity of community-acquired pneumonia in children, according to a study published in Pediatrics.
Arthritis Drug Presents Promise as Treatment for COVID-19 Pneumonia
UC San Diego Health has launched a Phase III clinical trial to assess whether a medication used to treat rheumatoid might also have therapeutic value for patient with COVID-19 who have developed or are at high risk of developing serious lung damage from SARS-CoV-2 infections.
Rates of Pulmonary Complications Drastically Reduced with Newer Drug
Improved pulmonary outcomes in surgical patients who receive the drug sugammadex could be due to a more complete reversal of the effects of muscle relaxants used during surgery.
Study Demonstrates the Need for Immediate ICU Care for Severe COVID-19 Pneumonia, Describes Patient Characteristics
Researchers have identified the most common clinical characteristics of 109 patients with COVID-19 related pneumonia who died in Wuhan, China in the early stages of the coronavirus pandemic, according to a new study published online in the Annals of the American Thoracic Society.
Artificial Intelligence Enables Rapid COVID-19 Lung Imaging Analysis at UC San Diego Health
With support from Amazon Web Services, UC San Diego Health physicians are using AI in a clinical research study aimed at speeding the detection of pneumonia, a condition associated with severe COVID-19.
@atscommunity #lung expert Dr. Michael Niederman weighs in on #COVID-19.
Michael Niederman, MD, is a member of the American Thoracic Society as well as clinical director and associate chief in the division of Pulmonary and Critical Care Medicine at Weill Cornell Medical Center, and professor of Clinical Medicine at Weill…
Russian biologist explains recent findings regarding coronavirus structure
MOSCOW (MIPT) — The atomic structure of the novel coronavirus envelope has explained why it is exceptionally contagious. Its structural features make it much easier for the Chinese coronavirus to bind to target receptors, compared with the previously known SARS…
Scientists May Have a Way to Let Preemies Breathe Easier
The continuing epidemic of pre-term birth includes this stark reality: tiny, fragile babies are born with underdeveloped lungs and prone to lifelong respiratory infections and related chronic illnesses. Cincinnati Children’s researchers report in Immunology the discovery of a complex biological process could in the development of cost effective treatments to help babies develop lifelong pulmonary resistance to respiratory infections.
Panicky Responses to the Coronavirus are Dangerous—Here’s Why
Fear of the virus may spread faster than the virus itself, a potential threat to health, liberty, trade, and the economy.
Russian expert is ready to comment on the coronavirus
Pavel Volchkov heads the Genome Engineering Lab at the Moscow Institute of Physics and Technology (MIPT), that has several key projects, all of them involving genome editing mediated by the CRISPR/Cas technology. Discovered just a few years ago, CRISPR/Cas has…
Why Experts Are Worried About a New Virus in China
The virus appears to be less dangerous than SARS, but there are still concerns of a wider outbreak in Asia.
Respiratory Groups Call for An End to Preventable Pneumonia Deaths
In support of World Pneumonia Day, Nov. 12, the Forum of International Respiratory Societies (FIRS), of which the American Thoracic Society is a member, calls for an end to preventable pneumonia deaths, ensuring equitable access to interventions for prevention and control of pneumonia.
AI System Accurately Detects Key Findings in Chest X-Rays of Pneumonia Patients Within 10 Seconds: Study Finds Promise of Faster Treatment
From 20 minutes or more to 10 seconds. Researchers from Intermountain Healthcare and Stanford University say 10 seconds is about how quickly a new system they studied that utilizes artificial intelligence took to accurately identify key findings in chest X-rays of patients in the emergency department suspected of having pneumonia.