COVID-19 vaccine elicits weak antibody response in people taking immunosuppressant

People taking TNF inhibitors, a kind of immunosuppressive drug used to treat rheumatoid arthritis and other autoimmune conditions, produced a weaker and shorter-lived antibody response after two doses of Pfizer’s COVID-19 vaccine, according to a study from Washington University School of Medicine in St. Louis. A third vaccine dose drove antibody levels back up, indicating that this additional dose may provide protection as the virus’s delta variant continues to spread.

Which older adults are getting flu shots and COVID boosters? Poll shows variation

With two viruses threatening to make older adults sick this winter, a new poll shows most people over 50 have gotten protected by vaccines against both influenza and coronavirus, or plan to. And a majority of those who have gotten the COVID-19 vaccine plan to get an additional dose. But the poll also reveals major differences in vaccine attitudes between older adults, including those of different political leanings.

COVID-19 Vaccine Gets Strong Response in Some With Weak Immunity

Researchers at Cedars-Sinai found that patients with inflammatory bowel disease (IBD)─whose treatment can weaken the immune system─produced a strong antibody response to COVID-19 vaccination. The study findings have been published in the Annals of Internal Medicine.

NYU Langone Presentations at American College of Rheumatology Convergence 2021 to Address Vaccine Efficacy and High-risk Pregnancy

NYU Langone rheumatologists are presenting their discoveries at the annual American College of Rheumatology conference, November 1 to November 9. The conference will be held virtually.

FDA authorization of COVID-19 vaccine for kids 5 to 11: IU experts available to comment

Following a daylong meeting Oct. 26, the FDA authorized Pfizer’s COVID-19 vaccine for use in children ages 5 to 11. This was the first in a series of meetings to make this vaccine available to younger children. Next, the Advisory…

Patients with Multiple Sclerosis Show Robust T-Cell Responses to mRNA COVID-19 Vaccines

New research shows that Multiple Sclerosis (MS) patients undergoing anti-CD20 (aCD20) treatment – which depletes the B cells that contribute to the MS attacks – are able to mount robust T-cell responses to the mRNA COVID-19 vaccines, despite having a muted antibody response to the vaccines.

The Lancet: Scientific evidence to date on COVID-19 vaccine efficacy does not support boosters for general population, expert review concludes

An expert review by an international group of scientists, including some at the WHO and FDA, concludes that, even for the delta variant, vaccine efficacy against severe COVID is so high that booster doses for the general population are not appropriate at this stage in the pandemic.

“Automated Vaccine Filling Machine”, An Innovation from Chulalongkorn University, Helps Boost the Number of Vaccinations by 20 Percent, and Reduce the Workload of Medical Personnel

The Faculty of Engineering, Chulalongkorn University has developed an automated vaccine filling machine that can fill AstraZeneca vaccine into syringes with precision, speed, and safety, helping to increase the number of vaccinated people by 20 percent. The prototype is now operating at Chula Vaccination Center and more machines are planned to be built to support frontline medical personnel in many vaccination centers soon.

COVID-19 mRNA Vaccine that Uses Fundamental Penn Technology Receives FDA Approval

PHILADELPHIA – The U.S. Food and Drug Administration (FDA) has given the first full approval to a COVID-19 mRNA vaccine, which uses modified mRNA technology invented and developed by scientists in the Perelman School of Medicine at the University of Pennsylvania, whose years of research in mRNA science laid a critical piece of the foundation for the largest global vaccination campaign in history.

Cancer Guidelines Organization Supports Mandatory COVID-19 Vaccination for Health Workers

National Comprehensive Cancer Network (NCCN) COVID-19 Vaccination Advisory Committee calls for healthcare workforce vaccine requirements to assure healthcare community is doing all it can to prevent exposure to COVID-19.

American Society of Anesthesiologists Strongly Encourages all Health Care Personnel to Get Vaccinated Against COVID-19

Amid the new surge of COVID-19 cases across the U.S., the American Society of Anesthesiologists (ASA), and eight professional societies associated with the specialty, are strongly encouraging the nation’s health care workers and all eligible Americans to get fully vaccinated with one of the COVID-19 vaccines. ASA and the associated societies remind the public that widespread vaccination is the most effective way to reduce illness and death.

COVID-19 Vaccine Protection Against Infection Lower and Slower in People with Liver Disease

A study shows for the first time that people with cirrhosis who receive mRNA COVID-19 vaccination gain important protection against more serious outcomes like hospitalization and death. At the same time, however, the vaccines offer less protection against SARS-CoV-2 infection and take longer to take effect in this population.

Phage Display-Based Gene Delivery: A Viable Platform Technology for COVID-19 Vaccine Design and Development

Researchers at Rutgers Cancer Institute of New Jersey, Rutgers New Jersey Medical School (NJMS) and the Center for Theoretical Biological Physics (CTBP) at Rice University in Houston, Texas, have demonstrated that a technology with favorable biological attributes known as phage display could be a viable platform for the development of new vaccines to protect against COVID-19.

mRNA Vaccines Slash Risk of COVID-19 Infection by 91 Percent in Fully Vaccinated People

People who receive mRNA COVID-19 vaccines are up to 91 percent less likely to develop the disease than those who are unvaccinated, according to a new nationwide study of eight sites, including Salt Lake City. For those few vaccinated people who do still get an infection, or “breakthrough” cases, the study suggests that vaccines reduce the severity of COVID-19 symptoms and shorten its duration.

GW Experts Available to Discuss Returning to the Office This Fall

WASHINGTON (June 30, 2021) — Now that COVID-19 vaccination rates in the United States have gone way up, many employers are calling workers back to the office. However, surveys show that many employees enjoy working from home and do not want…

Data and safety review board reports how it monitored the COVID-19 vaccine trials

Evaluation of three vaccine candidates during the COVID-19 pandemic fell to 12 experts of the federally appointed COVID-19 Vaccine Data and Safety Monitoring Board. This team has now taken the unusual step of publishing details of their review process in The Journal of Infectious Diseases.

FSU expert available to discuss vaccine hesitancy

By: Bill Wellock | Published: June 2, 2021 | 1:16 pm | SHARE: Rollout of the COVID-19 vaccine is continuing, but some people are hesitant to get vaccinated against the disease.Dr. Christie Alexander, an associate professor in the Department of Family Medicine and Rural Health in the Florida State University College of Medicine and a past president of the Florida Academy of Family Physicians, recently participated in an expert panel about how to win over vaccine skeptics.

Why are some Covid-19 vaccines working better for men than women?

If there’s one take-home message for the general public about the coronavirus vaccines approved in the U.S., it’s that they are remarkably effective. But Michigan State University’s Morteza Mahmoudi is raising awareness about an important subtlety: The vaccines developed by Moderna and Pfizer-BioNTech appear to work slightly better for men than for women.

Rutgers Expert Available to Discuss Waiving COVID-19 Vaccine Patents to Increase Global Vaccinations

Rutgers global health expert Richard Marlink is available to discuss the waiving of vaccine patents to help increase global vaccination rates in less developed countries — a move the Biden administration recently supported ahead of negotiations with the World Trade…