In new research published in Nature Medicine, Beth Israel Deaconess Medical Center immunologist Dan H. Barouch, MD, PhD, and colleagues demonstrated that the optimal vaccine elicited robust immune response in Syrian golden hamsters and prevented severe clinical disease — including weight loss, pneumonia and death.
Tag: COVID-19 Vaccine
Experimental vaccine that boosts antigen production shows promise against COVID-19
A bioengineering technique to boost production of specific proteins could be the basis of an effective vaccine against the novel coronavirus that causes COVID-19, new research suggests.
Hackensack Meridian Health Enrolling Individuals for COVID-19 Vaccine Clinical Trial
Hackensack Meridian Health investigators expect to enroll 300 individuals.
COVID-19 Vaccine Candidate Tested at University of Kentucky Shows Positive Preclinical Results
PDS Biotechnology, a clinical stage immunotherapy company, has announced positive results from preclinical testing conducted at the University of Kentucky College of Medicine of its COVID-19 vaccine candidate, PDS0203.
George Washington University to Conduct Clinical Trial for COVID-19 Experimental Vaccine
The George Washington University will participate in a clinical trial for an investigational COVID-19 vaccine.
Scientists Identify Targets for COVID-19 Vaccine Using Cancer Immunotherapy Tools
Cancer researchers at Children’s Hospital of Philadelphia (CHOP) have harnessed tools used for the development of cancer immunotherapies and adapted them to identify regions of the SARS-CoV-2 virus to target with a vaccine, employing the same approach used to elicit an immune response against cancer cells to stimulate an immune response against the virus. Using this strategy, the researchers believe a resulting vaccine would provide protection across the human population and drive a long-term immune response.
NYU Langone Among First to Enroll Patients In Clinical Trial for COVID-19 Monoclonal Antibody Treatment
The first patients were treated as part of a clinical trial testing whether an antibody therapy can safely reduce COVID-19 disease severity. The experimental treatment consists of identical copies of an antibody, a blood protein related to those that occur naturally as part of the human immune system, researchers say.
AAVCOVID Vaccine Program Expands Manufacturing Agreements with Gene Therapy Industry Partners Viralgen, Aldevron, and Catalent
The AAVCOVID vaccine program at Massachusetts Eye and Ear and Massachusetts General Hospital has entered into manufacturing agreements with Viralgen, Aldevron and Catalent in order to support manufacturing of the experimental vaccine for clinical studies in the second half of 2020.
Gene Therapy Program at Penn Medicine Joins AAVCOVID Vaccine Project
The internationally-renowned Gene Therapy Program at the University of Pennsylvania is joining the AAVCOVID vaccine program led by Massachusetts Eye and Ear and Massachusetts General Hospital (MGH), members of Mass General Brigham. AAVCOVID is a unique gene-based vaccine candidate designed to protect against SARS-CoV-2, the virus that causes COVID-19.
In victory over polio, hope for the battle against COVID-19
Medicine’s great triumph over polio holds out hope we can do the same for COVID-19, two researchers say.