The transatlantic slave trade may have introduced new pathogenic viruses from Africa to North America that affected Indigenous communities, shows an analysis of ancient DNA published in eLife.
PHILADELPHIA – For their landmark research that set a foundation for the mRNA SARS-CoV-2 vaccines, Drew Weissman, MD, PhD, the Roberts Family Professor of Vaccine Research, and Katalin Karikó;, PhD, an adjunct professor of Neurosurgery at the Perelman School of Medicine at the University of Pennsylvania and a senior vice president at BioNTech, have been selected to receive the 2021 Albany Prize.
People who are HIV positive and living in high tuberculosis-transmission regions of the world are much more likely to finish a TB-prevention regimen lasting just three months – half as long as the standard treatment, a large clinical trial in Africa has found.
For more than 40 years, UCI infectious disease researcher Michael Buchmeier has studied coronaviruses, and he’s one of the leading experts on SARS-CoV-2, the version of the virus causing the COVID-19 pandemic. As a more lethal mutation of the virus, called the delta variant, sparks another wave of cases, he offers his expertise about this threat.
Scientists at Children’s Hospital of Philadelphia (CHOP) have identified two proteins that could be used for a potential vaccine against nontypeable Haemophilus influenzae (NTHi). Working in a mouse model, the investigators found that administering two bacterial adhesive proteins that play a key role in helping the bacteria to latch on to respiratory cells and initiate respiratory tract infection stimulated protective immunity against diverse NTHi strains, highlighting the vaccine potential.
In a large observational study, Mayo Clinic researchers have shown that two monoclonal antibodies administered separately helped prevent hospitalization in high-risk patients who became infected with COVID-19. The study also showed more hospitalizations were observed among patients with more comorbidities. The findings appear in The Journal of Infectious Diseases.
NEWS STORIES IN THIS ISSUE:
– Johns Hopkins Medicine Celebrates Its Contributions to Keto Therapy as Diet Turns 100
– COVID-19 News: Can Dietary Supplements Help the Immune System Fight Coronavirus Infection?
– Johns Hopkins Medicine Helps Develop Physician Training to Prevent Gun Injuries, Deaths
– COVID-19 News: Study Says Pandemic Impaired Reporting of Infectious Diseases
– Johns Hopkins Medicine Helps Create Treatment Guide for Neurodegenerative Disorders
– Johns Hopkins Pediatrics Says, ‘Get Kids Required Vaccines Before Going Back to School’
Researchers at Johns Hopkins Medicine have shown that a type of echocardiogram, a common test to evaluate whether a person’s heart is pumping properly, may be useful in predicting which patients with COVID-19 are most at risk of developing atrial fibrillation — an irregular heartbeat that can increase a person’s risk for heart failure and stroke, among other heart issues. The new findings, published online May 30 in the Journal of the American Society of Echocardiography, also suggest that patients with COVID-19 who go on to develop atrial fibrillation more commonly have elevated levels of heart-related proteins called troponin and NT-proBNP in blood test samples.
Penn State researchers are leading a multi-country collaboration to develop a surveillance modeling tool that provides a weekly projection of expected COVID-19 cases in all African countries.
UC San Diego School of Medicine researchers discovered that SARS-CoV-2, or at least its genetic signature, abounds on hospital surfaces, often co-locating with one particular type of bacteria.
With the dangers of Covid-19 waning, and summer nearly upon us, another infectious disease danger remains present for our Long Island population and the region – tick-borne illnesses. Stony Brook experts have been sharing their tick expertise with the community…
In previously unstudied gopher tortoise aggregations, researchers found that overall, 42.9 percent had circulating antibodies to an infectious bacterium that causes upper respiratory tract disease. Physical examination showed that 19.8 percent had clinical signs consistent with upper respiratory tract disease and 13.2 percent had some form of physical abnormality. None of the tortoises tested positive for Ranavirus or Herpesvirus, which represents important baseline data, since these viruses are thought to be emerging pathogens of other tortoise and turtle species.
People who received a flu shot last flu season were significantly less likely to test positive for a COVID-19 infection when the pandemic hit, according to a new study. And those who did test positive for COVID-19 had fewer complications if they received their flu shot.
The global fight against tuberculosis is gaining some powerful tools. Precision medicine — already used to personalize diagnosis and treatment of noncommunicable diseases such as cancer — and health care technologies such as telemedicine have the potential to advance the prevention and treatment of tuberculosis, says Zelalem Temesgen, M.D., an infectious diseases expert and medical director of the Mayo Clinic Center for Tuberculosis.
Mayo Clinic’s Coronavirus Map tracking tool, which has county-by-county information on COVID-19 cases and trends nationwide, now offers predictive modeling that forecasts where hot spots will emerge over the next 14 days.
A new SARS-CoV-2 vaccine candidate, developed by giving a key protein’s gene a ride into the body while encased in a measles vaccine, has been shown to produce a strong immune response and prevent SARS-CoV-2 infection and lung disease in multiple animal studies.
Reports on variants of the coronavirus that causes COVID-19 have swept the news over the past few months, but what exactly is a virus variant?
UC San Diego School of Medicine researchers are using stem cell-derived organoids to study how SARS-CoV-2 interacts with various organ systems. Their findings may help explain the wide variety in COVID-19 symptoms and aid the search for therapies.
In a study published in Open Forum Infectious Diseases, researchers at Children’s Hospital of Philadelphia (CHOP) describe the array of rashes seen in MIS-C patients at their hospital through late July 2020, providing photos and information that could help doctors diagnose future cases.
Advances in the fields of biomaterials and nanotechnology could lead to big breakthroughs in the fight against dangerous viruses like the novel coronavirus that causes COVID-19. In APL Bioengineering, researchers from the Indian Institute of Science describe possibilities being explored by scientists, combining biomaterials and nanotechnology, to make vaccines more effective and build surfaces that could fight and kill viruses on their own.
After years of paltry funding, research on the possible role of microbes in the causation of Alzheimer’s disease will now get a major infusion of grants from the NIH’s National Institute on Aging
U.S. public health officials have reported that Black communities are disproportionately affected by the COVID-19 pandemic, with higher infection and mortality rates than the general population. Now as the number of COVID-19 cases across the U.S. surge, Mayo Clinic researchers are working closely with Black churches on disparities in emergency preparedness and providing access to culturally relevant, evidence-based health information.
Researchers from the National University of Singapore have utilised a ground-breaking AI platform to find an optimal combination of available therapies against COVID-19. The research team identified the drug combination from over 530,000 possibilities within two weeks, cutting down the number of tests typically needed by hundreds of thousands.
Irvine, Calif., Dec. 8, 2020 — University of California, Irvine public health experts are providing consulting services to Pacific Symphony to enable the Orange County ensemble to once again play music together – which hasn’t happened since early March because of the coronavirus pandemic. In the past months, Pacific Symphony has held online events – including virtual concerts, living room concerts on video, internet interview programs, and KCET and PBS SoCal’s “Southland Sessions Presents Pacific Symphony” series – featuring offerings from the orchestra’s archival vaults.
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Tuesday.
DALLAS – Nov. 12, 2020 – UT Southwestern researchers have discovered a mechanism that cells use to degrade microRNAs (miRNAs), genetic molecules that regulate the amounts of proteins in cells.
With thousands of new cases logged daily and a vaccine to fight COVID-19 still in development, UCLA Health infectious disease experts are encouraging people to continue to wear masks as the best method of protecting against virus transmission.
UNC-Chapel Hill scientists discovered that many rhinoviruses need a human protein called STING to make copies of its RNA, opening the door to a new strategy for controlling infection of these pesky and at times very dangerous pathogens.
Dr. David Eisenman is director of the UCLA Fielding School of Public Health’s Center for Public Health and Disasters and professor-in-residence of community health sciences at the UCLA Fielding School of Public Health. Dr. Jonathan Fielding is a distinguished professor…
Irvine, Calif., Oct. 1, 2020 — Uneven population distribution can significantly impact the severity and timing of COVID-19 infections within a city or county, leading individual communities to have vastly different experiences with the pandemic, according to a recent study led by the University of California, Irvine. Findings published in Proceedings of the National Academy of Sciences show that the heterogeneous spatial features of interpersonal connections may produce dramatic local variations in exposures to those with the illness.
As the COVID-19 pandemic continues with no end in sight, the annual flu season emerges once again. Cases of the flu have already begun to surface around the nation, and there are some reports of co-infection with COVID-19. Johns Hopkins Medicine experts say now is the time to take action to fight against the flu. Doctors recommend that everyone age 6 months and older get the flu vaccine each year to prevent infection from the virus or reduce the severity of the illness.
A bioengineering technique to boost production of specific proteins could be the basis of an effective vaccine against the novel coronavirus that causes COVID-19, new research suggests.
Irvine, Calif., Aug. 10, 2020 — Scientists at the University of California, Irvine have unveiled a public website that provides up-to-date statistics on coronavirus infections in Orange County, with comparisons to neighboring and other California counties. The site displays information collected from the California Open Data Portal in an easily comprehended format, giving visitors quick access to the most relevant data on hospitalized patients with COVID-19, intensive care unit patients, new daily cases and new daily deaths caused by the disease.
The leadership team at Texas Biomedical Research Institute is excited to announce the addition of Akudo Anyanwu, M.D., M.P.H. to its administrative leadership team as Vice President of Development.
New Brunswick, N.J. (Aug. 3, 2020) – Rutgers University–New Brunswick Professor Robert E. Kopp is available to discuss a major study released today on the global consequences of climate change on death rates. The study by the Climate Impact Lab,…
A prominent Australian pharmacologist has called for a new approach to treating COVID-19 as hopes fade of finding an effective vaccine or antiviral before the end of the year.
Researchers at University of California San Diego School of Medicine and UC San Diego Health have launched a clinical trial to assess the safety and efficacy of convalescent plasma (CP) to prevent COVID-19 after a known exposure to the virus.
In response to the high demand for one of the fastest-growing jobs in the U.S., FAU has launched a new, online public health certificate course on COVID-19, contact tracing and risk-reduction. The five-week, 15-hour course does not require a college degree and is scheduled from June 29 to Aug. 7. The program is open to the general public for adults age 18 and older with a high school diploma or equivalent and a variety of work experiences and educational backgrounds.
UVA Health has partnered with the Virginia Department of Health and other hospitals around the state to determine how many Virginians have been infected with COVID-19 – and how many remain at risk.
Necessity being the mother of invention, Houston Methodist clinicians, researchers and staff have collaborated on a number of clinical device and research innovations in response to COVID-19. Houston Methodist Academic Institute leadership has continually emphasized translational research in new technologies.
Researchers at UC San Diego Health report in newly published findings that olfactory impairment suggests the resulting COVID-19 disease is more likely to be mild to moderate, a potential early indicator that could help health care providers determine which patients may require hospitalization.
With support from Amazon Web Services, UC San Diego Health physicians are using AI in a clinical research study aimed at speeding the detection of pneumonia, a condition associated with severe COVID-19.
UC San Diego Health makes measurable progress addressing COVID-19 testing shortage through multiple partnerships and rapidly growing in-house testing. Success has meant more testing for more patients, first responders and other health systems.
Researchers at four University of California Health medical centers have begun recruiting participants for a Phase II clinical trial to investigate the safety and efficacy of treating adult patients with COVID-19 with remdesivir, a drug that has shown promising activity against multiple viruses.
One-third of Americans do not have access to paid sick leave. Only the U.S. and Japan do not mandate a national sick leave benefit. Currently, seven states in the U.S. mandate that employers provide paid sick leave benefits. Given the latest information from the U.S. CDC regarding the potential impact that the coronavirus could have on the nation, researchers urge that it is critical to consider the role paid sick leave has in stopping the spread of a contagious virus.
In a letter to the Food and Drug Administration (FDA), AACC is urging the agency to allow clinical laboratories to develop coronavirus tests without going through FDA review. Lifting this regulatory requirement is key to ensuring that all patients have access to high-quality coronavirus testing and that healthcare workers have the tools they need to control the spread of this disease in the U.S.
Doctors from the University Hospitals (UH) Roe Green Center for Travel Medicine provide the following health tips for vacationers thinking about a cruise in light of the novel coronavirus (COVID-19) outbreak. 1. As always, the best infection control measure is…
Experts believe that tuberculosis, or TB, has been a scourge for humans for some 15,000 years, with the first medical documentation of the disease coming out of India around 1000 B.C.E. Today, the World Health Organization reports that TB is still the leading cause of death worldwide from a single infectious agent, responsible for some 1.5 million fatalities annually. Primary treatment for TB for the past 50 years has remained unchanged and still requires patients to take multiple drugs daily for at least six months. Successful treatment with these anti-TB drugs — taken orally or injected into the bloodstream — depends on the medications “finding their way” into pockets of TB bacteria buried deep within the lungs.
Experts from the University of Alabama at Birmingham are avaliable to comment on the state of COVID-19, including the development of an investigational compound at UAB, next steps for a vaccine, what the state of the outbreak looks like, what…
Wearing a surgical mask is unlikely to protect healthy people from the novel coronavirus that originated in China, and influenza likely poses a much greater threat to Americans, according to José Cordero, professor of epidemiology and biostatistics in the University of Georgia’s College of Public Health.